Cfor019152.1
Basic Information
- Insect
- Cylas formicarius
- Gene Symbol
- ZFX
- Assembly
- GCA_029955315.1
- Location
- JARGXY010000010.1:12463327-12464631[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00034 0.028 15.2 1.3 1 23 12 34 12 34 0.99 2 11 0.00027 0.022 15.6 0.0 1 20 40 59 40 60 0.96 3 11 7e-05 0.0056 17.4 1.7 1 23 73 95 73 95 0.98 4 11 1.3e-06 0.0001 22.9 0.1 1 23 101 123 101 123 0.98 5 11 0.00022 0.018 15.8 1.8 1 23 129 151 129 151 0.98 6 11 4.9e-06 0.0004 21.0 2.8 1 21 157 177 157 180 0.95 7 11 0.0008 0.064 14.1 5.0 1 23 186 206 186 206 0.98 8 11 5.6e-06 0.00045 20.9 1.9 3 23 214 234 213 234 0.99 9 11 6e-06 0.00048 20.8 1.9 1 23 240 262 240 262 0.99 10 11 0.00015 0.012 16.4 0.2 1 20 268 287 268 288 0.97 11 11 1 84 4.3 1.4 1 19 297 315 297 318 0.92
Sequence Information
- Coding Sequence
- ATGACGTTCTCGACGGACGACAAACCGCGCAAGTATCGCTGCGACGTATGCGACAAGCGCTTCCTGGGCACCAACGACCTAAAGAAACACAAAAGGGTGCATACCGACGAACGACCGTACGTATGCAACGAGTGCGGCGTCGGGTTCCGTCAGGGCGGTTCCCTGAAGAACCACATCGCTTGCAAACACTCGCCAGGACTGCAGAGCAAAGAGGTGTTCGTGTGCGAGTACTGCAACAAACACTTCCCGATAAAGGAAAGGTTGCGACTGCACCTGCGCGTCCACACAGGCGACCGTCCGTACGATTGTGACGTGTGCGACAAAAAGTTCGCGCGCGGCGGCCAGTTGGCGCAGCACATGCGCGTTCACACCAAAGACAAACCGTACGTTTGTCGTTTGTGCGACGCGAGCTTCACGTGCTCCGCCAACCTGAAGCTGCACATGAACCGACACCTCGACATACGTCAGTTCGTATGCGACATCTGCGGCAAATCGTTCTTCAGACGGGACGCGTTGAGGAAACACCTCAATTGTTACCACTCGAACGTGAAAGCGTTCCACTGCGACGTGTGCGACAAAGACTTCAAGGGACACCTGCAACAGCACATGAGAACGCACGTGAACGAAAAACCGCACGGCTGCGCGCACTGCGGCGCGAGGTTCGCGCAGAGATCGCACTTAACGGTCCATCAGAGGATACACAGCGGCGAGAAACCTTACCGCTGCCAGGTGTGCTGGAAAGCGTTCGCGCACTCTACCGCGCTCAAGCTCCACACCAGGAGGCACACCGGAGAAAAGCCGTTCCAGTGCGCAGTGTGTAACACGGGGTTCGCACAGCTACCGCACTTGAAGAAGCACATGGTATGCATCCACAAGAGTGACAAGCCGTACTGCTGCGGTTCGTGCAGGGGCTTCTACAAGACGAAGAGCGAGCTCGAGGGTCACGAGACGCGGTGCAAGCAAAAGAAAAAAGGCGATACGTCTAAAGGTCACGACCCGAAAGTAGAGCCGCCGATGTCTTTGCAAAAGATGCGGCTCCTGTTGGCCGTCTTGCTGAAGAAGATATCGACCAGGGAGCGACTCGACGAGCTGGGGTTCAACAAGAGGCTGATCGACGACATCCTGGTGGATTCGATCGAGAATTCGGGCAGGAAACCCTGCGCCGAGGACGGACTGTCGATTGCTGAAAAGTTAAAGAGGAACATCCAGATTTTGCTGGAGTGGACCGTGCCGGATTACTATATGGAGAAGTTTAAGACCGAGCAGAGGTCCACTGAAGAGTTGCTCGAAGAGTTGACCTCGTAG
- Protein Sequence
- MTFSTDDKPRKYRCDVCDKRFLGTNDLKKHKRVHTDERPYVCNECGVGFRQGGSLKNHIACKHSPGLQSKEVFVCEYCNKHFPIKERLRLHLRVHTGDRPYDCDVCDKKFARGGQLAQHMRVHTKDKPYVCRLCDASFTCSANLKLHMNRHLDIRQFVCDICGKSFFRRDALRKHLNCYHSNVKAFHCDVCDKDFKGHLQQHMRTHVNEKPHGCAHCGARFAQRSHLTVHQRIHSGEKPYRCQVCWKAFAHSTALKLHTRRHTGEKPFQCAVCNTGFAQLPHLKKHMVCIHKSDKPYCCGSCRGFYKTKSELEGHETRCKQKKKGDTSKGHDPKVEPPMSLQKMRLLLAVLLKKISTRERLDELGFNKRLIDDILVDSIENSGRKPCAEDGLSIAEKLKRNIQILLEWTVPDYYMEKFKTEQRSTEELLEELTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -