Basic Information

Gene Symbol
Znf784
Assembly
GCA_947568885.1
Location
OX387701.1:1423567-1444681[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.0074 0.46 11.6 1.2 1 23 316 338 316 338 0.99
2 23 6.7 4.1e+02 2.3 3.2 1 23 345 368 345 368 0.93
3 23 0.032 2 9.6 3.8 1 23 399 422 399 422 0.98
4 23 0.00023 0.015 16.4 0.7 2 23 431 453 431 453 0.95
5 23 0.15 9.1 7.6 0.9 2 21 462 481 461 482 0.92
6 23 0.086 5.4 8.3 0.3 3 23 495 516 494 516 0.89
7 23 2.9e-05 0.0018 19.2 0.6 1 23 521 544 521 544 0.97
8 23 5.6 3.5e+02 2.6 1.1 2 12 571 581 570 587 0.83
9 23 4.7 2.9e+02 2.8 0.1 2 11 613 622 612 625 0.84
10 23 4.7 2.9e+02 2.8 0.1 2 11 697 706 696 709 0.84
11 23 4.7 2.9e+02 2.8 0.1 2 11 781 790 780 793 0.84
12 23 4.7 2.9e+02 2.8 0.1 2 11 865 874 864 877 0.84
13 23 4.7 2.9e+02 2.8 0.1 2 11 949 958 948 961 0.84
14 23 4.7 2.9e+02 2.8 0.1 2 11 1033 1042 1032 1045 0.84
15 23 4.7 2.9e+02 2.8 0.1 2 11 1117 1126 1116 1129 0.84
16 23 4.7 2.9e+02 2.8 0.1 2 11 1201 1210 1200 1213 0.84
17 23 4.7 2.9e+02 2.8 0.1 2 11 1285 1294 1284 1297 0.84
18 23 4.7 2.9e+02 2.8 0.1 2 11 1369 1378 1368 1381 0.84
19 23 4.7 2.9e+02 2.8 0.1 2 11 1453 1462 1452 1465 0.84
20 23 0.046 2.8 9.1 3.4 2 23 1537 1558 1536 1558 0.97
21 23 0.00039 0.024 15.7 0.3 1 23 1564 1586 1564 1586 0.96
22 23 0.002 0.12 13.4 0.7 2 23 1593 1614 1592 1614 0.97
23 23 0.00015 0.0092 17.0 2.4 1 23 1620 1643 1620 1643 0.96

Sequence Information

Coding Sequence
ATGGACACAGTGAAAGTGGAGGAACAGTCGTTGTTGGCATGTCGTATTTGTCTGGCTTGGGACGTGAAATTGCATCATATCCGTGAGTCGGGATTAGATCGAATGTTTTCGGATATTATGGGAACTTCGCTATTAGCATGGGATGGGCTGCCACAACACCTGTGCGTGTGGTGCCGCGCGCAGCTGGCGCGGGCGCAGGCGCTGCGCGCACGCTGCAGCCGCGCCGACTCGCTGCTCAAGCAGGCACTCGTGCAACAGCATATTATAACAAACGAATATATCCGCACAATTAATCGTTCAACGCACAAATTCACGCACACACTCTCAACCAAAATATTTAATGAAGACGCTACTTATTATTATAACTACGACACACAGGCGAATTTATACAACTCATGTTTCATAAATAACAATGGACAAATTAATGCCGATATGGAAAATGATAACATAAATGTCGATTTACAAAATGATTCATGTTCAGAGTTAGACGTAGACAAATTAGAACGTGAGCATGATATCAATGTTAGATTAAATGATAATATCAGTAACATAGATGAAAATATAAATTTACCTGAAGAAGAAATAGTTGAAAGTTTAGATTTACAGTTTAAAAAGGTAAAATCCAAGAAAAACAGACTGTCTAGAAAAAGACATGACAAGAAGATTAAAGTTACAAAGCAAATAGAACAAATAGAAATAGTTGACACTTGTTCAGATAAAGAAATAGACATAAATAGAAAAAGACCGACTAGACGAAAAATGAAAGAGCAAGAAATGGACAAAGTAAGAAAAAGGAAAGAGCGCTCAAAGCAAAAGTTTTGTACTGAACATGATTTCAAAGAATTTGAGAAGAAATACGATTTCCAAGTGCAGTGTTTGACTGAAGAAGAAATGGAGAAGGAGATGGAGAAAAGAAAAGAATCTGACAAGTATCTTAAGGGAGAGTACAAGTGTGAGTTGTGTTATAAAGGGTTCCTGACGTCGGTCACGTACGAGAACCACATAAAGACTCATGATCCGGCACGCGGCCAACACGCCTGCCGGCTGTGCCACGTGCGGTACCAGTTTCCAGTGAAGCTTCGCCAGCATGTGCAGAATACCCACCGGCTAAAATTCCGATGCGCGCGGTGCAACGAACTCGTGCGCGGCAAGGCGTGCGCCGTGTTACACGCGGCGTACCACGCGGGTACCACGTTCCAGTGCGCGCATTGCGACAAACAGTTTCTTAAAAAAACATCGCGCACTTCACACATGCGCATGGCTCATCCAGTCGAGAACGCGGCCGGGGGCACCTGCGAGGTGTGTGGGGAGACCTTTACCAGCCGCACGGGCCTTAAGGCACACAAGACCCGAAGCCACAAGAAGGTTAATTTGCCTGAACTTAGATGCCGGAAGTGTAGGACACAGTTCGACAACATGGACGCTCTGAAGAAGCATAAAGAAACGTATCCGAACAGCAAGTGTGATTCCAGCCTGAGCGCGTGCTCGCAGTGCGGGGAGAGCTGCGCGAGCGCCGACGCTCTGATCCTGCATGCGCACGCGCAGCACGGCGTGCAATTGTACACCTGCGATACTTGCACGAAATCCTTCACATCGAAGCCGTCGCTCGCGACGCACATCGACCGCGTGCACCGGCTGCTGCGGCCGCCAAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCGTGAGTATAGACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCACTCTGTTACCACCGGCTGCTGCGGCCGCCCAAGGCCGACTACAGCGACGGCGGCCGCCGCTCGCAGCCCGACTGGCTGCACTGGGCCTCCGTGTGCGAGCACTGCGGGAAGCGACTCTCCTGCCTGGCGACGCTGAAGATACACATGAACAAACACACGGGGGAGAGACCGTACAAGTGCTCGCTGTGCCCCAAGGCCTACATGACGCCCTACGGACTTAACAACCACCAAGCGTTTCACACAGGTGTGAGGAAGTGGCAGTGCCCGGATTGTCCCGCCACCTTCATGCACCAGTCTTCCGTCTACCAGCATAAAAAGATACACACAGGCGAGCGGTCCCACCAATGCACAATCTGCGAGAAATACTTCACGCAGTCGGGGTCGCTCTACACGCACATCAAATATGTGCATATGAAGGAGACACCTCCTCCGCGCAAGCGCAACAAGAAACCTGTCCAACATTAG
Protein Sequence
MDTVKVEEQSLLACRICLAWDVKLHHIRESGLDRMFSDIMGTSLLAWDGLPQHLCVWCRAQLARAQALRARCSRADSLLKQALVQQHIITNEYIRTINRSTHKFTHTLSTKIFNEDATYYYNYDTQANLYNSCFINNNGQINADMENDNINVDLQNDSCSELDVDKLEREHDINVRLNDNISNIDENINLPEEEIVESLDLQFKKVKSKKNRLSRKRHDKKIKVTKQIEQIEIVDTCSDKEIDINRKRPTRRKMKEQEMDKVRKRKERSKQKFCTEHDFKEFEKKYDFQVQCLTEEEMEKEMEKRKESDKYLKGEYKCELCYKGFLTSVTYENHIKTHDPARGQHACRLCHVRYQFPVKLRQHVQNTHRLKFRCARCNELVRGKACAVLHAAYHAGTTFQCAHCDKQFLKKTSRTSHMRMAHPVENAAGGTCEVCGETFTSRTGLKAHKTRSHKKVNLPELRCRKCRTQFDNMDALKKHKETYPNSKCDSSLSACSQCGESCASADALILHAHAQHGVQLYTCDTCTKSFTSKPSLATHIDRVHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSYRLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSVSIDSVTTGCCGRPRPTTATAAAARSPTGCTGPPCASTAGSDSPLCYHRLLRPPKADYSDGGRRSQPDWLHWASVCEHCGKRLSCLATLKIHMNKHTGERPYKCSLCPKAYMTPYGLNNHQAFHTGVRKWQCPDCPATFMHQSSVYQHKKIHTGERSHQCTICEKYFTQSGSLYTHIKYVHMKETPPPRKRNKKPVQH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-