Basic Information

Gene Symbol
-
Assembly
GCA_963556715.1
Location
OY750816.1:2883425-2899671[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.3 19 6.9 2.9 1 23 327 350 327 350 0.98
2 24 2 1.3e+02 4.3 0.5 2 23 358 380 358 380 0.94
3 24 0.00057 0.037 15.5 2.6 2 23 412 434 412 434 0.96
4 24 0.009 0.58 11.7 0.1 2 23 443 465 443 465 0.92
5 24 0.22 14 7.4 0.2 2 21 474 493 473 494 0.92
6 24 4.2 2.7e+02 3.3 0.0 3 23 507 528 505 528 0.90
7 24 0.0035 0.23 13.0 0.5 1 23 533 556 533 556 0.96
8 24 0.19 12 7.6 4.2 1 21 587 606 587 611 0.90
9 24 0.072 4.7 8.9 2.1 1 21 618 637 618 642 0.90
10 24 0.15 9.7 7.9 2.0 1 21 649 668 649 673 0.88
11 24 0.037 2.4 9.8 0.1 1 16 680 695 680 696 0.89
12 24 0.15 9.7 7.9 2.0 1 21 735 754 735 759 0.88
13 24 0.037 2.4 9.8 0.1 1 16 766 781 766 782 0.89
14 24 0.15 9.7 7.9 2.0 1 21 821 840 821 845 0.88
15 24 0.31 20 6.9 0.2 1 13 852 864 852 866 0.86
16 24 0.037 2.4 9.8 0.1 1 16 920 935 920 936 0.89
17 24 0.15 9.7 7.9 2.0 1 21 975 994 975 999 0.88
18 24 0.00077 0.05 15.1 7.3 1 23 1006 1028 1006 1028 0.97
19 24 2.7e-06 0.00017 22.8 0.7 1 23 1034 1056 1034 1056 0.99
20 24 0.00043 0.027 15.9 0.7 1 21 1062 1082 1062 1083 0.96
21 24 0.00043 0.027 15.9 0.7 1 21 1096 1116 1096 1117 0.96
22 24 0.00043 0.027 15.9 0.7 1 21 1130 1150 1130 1151 0.96
23 24 0.0018 0.12 13.9 2.6 2 23 1165 1187 1164 1187 0.93
24 24 2.2e-05 0.0014 20.0 0.4 2 23 1195 1217 1194 1217 0.96

Sequence Information

Coding Sequence
ATGCCTTTACCTTTAGTATTAGTGAACATGGACACAGTGAAATTGGAGGAACAATCGGAGTTGAAGGCATGTCGGATTTGCCTGGCTTGGGATGTCAAATTGTATCACATTCGCGAGTCTGGCTTAGATCAAATGTTCTCGGAAATTATGGGAATTTCGATTACAGCATCAGATGGGCTACCTCAACACTTATGCAGCTGGTGTCGCACACTGCTGCTAAAAGCAGTGAGGCTGCGAGCTTGCTCAAGACGATCAGACGGCTTGCTACGACAAGCGCTCACACAGCAACAGTCAATAACAAACGAATACATCCGGACTATAGACCGTTCTATACACAAATTGACACGCACACTCTcgcaaaacttaaaaactaccaTCCAGTATTACTTTGGACAAGACGAAACATTGGATAGTGTAAATGTCCATCCAGATATCGATATCATCAAAGATGAGATAGAACCAAACGAAAATGATTTGAACAGTAAACATGATAAGGTAGAAACAGATATATTACAGATTAATATAATGGAAACTGACATCAAAGCGTTTGATTTAAATTGCGACGCTACAGCAGACAGTGATTCTGATGAAGATTCTAAAATGAATCTTCgagaatataaatataaaatggaaaattttgagTCAAAACCTGCATTAGTCGAAGTTAAAATAGGAACGAGATTAGATAAACGTATAAAGAATGTCTCAAAAAGACTAAAGGAAGTTAATGTAGAaacatttcaaaataaaaagcGAGAATCGAAAGCCAATAAAGTAAGAAAGAAACATAAGGAAACAAAAGAAGTAAAAACAAAAGCTGTTAAAGAAAAAGATTCAGAACCAGGAAGGTTTTTTACAATAGAGGATATAGAAGAGTTTGTAAAAAAGCATAATTTTGAAATACAGTATTTGACTGAGGAAGAAATGGCGGAGGATATGGAAAGGAGAAAAATGTCGGATCGGTATAAGCATTGCAAGTTTAAATGTAACTTGTGTTATAAAGGCTTTCTGACCACCACTACTTTTGATAATCATATGAAGAAAGATCATGATccgCGTAACGCAAAGAACGAGTGCCGATTATGCCGCGTCAGCTACCGGTACGGGTTCTACCTCAAACAGCACGTGCAGAATGCGCACCGGCTGCGGCTGCGCTGCGCCGAGTGCGGCGAGGGCGTTTGGGGCAGGAAAGAGTGCGTCGCGCACGCGGCGCGCCACGCCGGGACCACGCGGCAATGCAAGTACTGCGGGAAGCATTTCCTTAAGAAATCGTCGTACACATGGCATATGCGAGCAGCACATCCCGTCGAGAACTCTGCGCGCGGCTCGTGCGAGCTATGTGGGGAGATCTACACAAGTGCCAAGGGACTCAAGGCGCATAAACTACTTGCACATAATAAGCGCTCTGCGCCCGAGTTAGAGTGCGGCAGCTGCCGCGCACAGTTCGACAATAAGGAGGCTCTGACGAAACACAGACAGCAGCAAGATGACGGCAAGTGTGATCCGGACTTAAGCCCGTGTGCGGCGTGCGGCGCGGGCTGCGCAGGCGCCGAGGCGCTGCTACGGCACATGCATGCGGCGCACAATGTCGAAATCTTCACCTGTGACCTCTGCAACAAATCCTTTCTATCCAAGCCTTCGCTCTCGACCCACATAGACCGCGTCCACCTCGGCATAAGGCCGTTACAGCACCACCAGCTCACTCATTACAAGAAGCATAGCAATCGCCCCGTGCAGCACAAGAGGCGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGCTCACTCATTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGAAAGGCCTACACGCTCGCACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGGCGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGCTCCCACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGACCTACACGGTAAACGCAACACTTACACCTACGAACATAAATCGCGTCCACCTCGGCATAAGACCGTTACAACACCACCAGCTCACACAGTACAAGAAGCACAGCAAGCGCCCCGTGCAGCACAAGAGGCGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGCTCCCACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGACCTACACGGTAAACGCAACACTTACACCTACGAACATAAATCGCGTCCACCTCGGCATAAGACCGTTACAACACCACCAGCTCACACAGTACAAGAAGCACAGCAAGCGCCCCGTGCAGCACAAGAGGCGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGCTCCCACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGGTAAAAGCAACACATACACCTGCGAGTAATGCAAACACATACACCTGCGATAATGCAAACACAGACACACATCGCGTCCACCTCGGCATCAGGCCGCTACAACACCACCAGCTCACACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGACCTACACGGTAAACGCAACACTTACACCTACGAACATAAATCGCGTCCACCTCGGCATAAGACCGTTACAACACCACCAGCTCACACAGTACAAGAAGCACAGCAAGCGCCCCGTGCAGCACAAGAGGCGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGCTCCCACAGTACAAGAAGCACAGCAAGCGGCCCGTGCAGCACAAGAGACGGGGGCACGACCACATGTGCGAGCACTGCGGGAAGGCCTACACGACACATCAGTTTCTGAAGAATCATCAGATGACGCACACGGGTGAGCGGCCTTTCAAGTGCGACCGCTGCCCTAAAGGGTTCACCACTGCTGTGCAGCTCACGTGGCACACCAGAACACACACGGGGGAGCGTCCATTCCAGTGCGACCAGTGTCATCAGGCGTTCAGTCTCGAAGGCAACCTCAGGAGGCACCGCAAAGCGGCGTACAGCCTTGGAACACACACGGGGGAGACTCCGTTCCAGTGCGACCAGTGTCATCAGGCGTTCAGTCTCGAAGGCAACCTGAGGAGGCACCGCAAAGCGGCGTTCAGCCTTGAAACACACACGGGGGAGACTCCGTTCCAGTGCGACCAGTGTCATCAGGCGTTCAGTCTCGAAGGCAACCTGAGGAGGCACCGCAAAGCGGCGTACAGCCTAGGAACACACACGGGGGAGACTCCGTGTCAGTGCGAACAGTGTCATCAGGCGTTCAGTTTAGAAGGCAACTTAAGGAGGCACCGCAATGCGGTGCACCTAGGCCTCCGAAAGAATGTGCCGTGCCCTCGCTGCGAGAAAACCTTTTCCACTAACTCCACCATGAAGCTGCACGTCAGAACAGTGCACGACGGAGCGCCCTGGCCGCGCCGGGACCGCAGGCCGAGGAAACAGCCGCCGCAGATAACAGAATAG
Protein Sequence
MPLPLVLVNMDTVKLEEQSELKACRICLAWDVKLYHIRESGLDQMFSEIMGISITASDGLPQHLCSWCRTLLLKAVRLRACSRRSDGLLRQALTQQQSITNEYIRTIDRSIHKLTRTLSQNLKTTIQYYFGQDETLDSVNVHPDIDIIKDEIEPNENDLNSKHDKVETDILQINIMETDIKAFDLNCDATADSDSDEDSKMNLREYKYKMENFESKPALVEVKIGTRLDKRIKNVSKRLKEVNVETFQNKKRESKANKVRKKHKETKEVKTKAVKEKDSEPGRFFTIEDIEEFVKKHNFEIQYLTEEEMAEDMERRKMSDRYKHCKFKCNLCYKGFLTTTTFDNHMKKDHDPRNAKNECRLCRVSYRYGFYLKQHVQNAHRLRLRCAECGEGVWGRKECVAHAARHAGTTRQCKYCGKHFLKKSSYTWHMRAAHPVENSARGSCELCGEIYTSAKGLKAHKLLAHNKRSAPELECGSCRAQFDNKEALTKHRQQQDDGKCDPDLSPCAACGAGCAGAEALLRHMHAAHNVEIFTCDLCNKSFLSKPSLSTHIDRVHLGIRPLQHHQLTHYKKHSNRPVQHKRRGHDHMCEHCGKAYTLTHYKKHSKRPVQHKRRGHDHMCEHCGKAYTLAQYKKHSKRPVQHKRRGHDHMCEHCGKAYTLPQYKKHSKRPVQHKRRGHDHMCEHCGKTYTVNATLTPTNINRVHLGIRPLQHHQLTQYKKHSKRPVQHKRRGHDHMCEHCGKAYTLPQYKKHSKRPVQHKRRGHDHMCEHCGKTYTVNATLTPTNINRVHLGIRPLQHHQLTQYKKHSKRPVQHKRRGHDHMCEHCGKAYTLPQYKKHSKRPVQHKRRGHDHMCEHCGKAYTVKATHTPASNANTYTCDNANTDTHRVHLGIRPLQHHQLTQYKKHSKRPVQHKRRGHDHMCEHCGKTYTVNATLTPTNINRVHLGIRPLQHHQLTQYKKHSKRPVQHKRRGHDHMCEHCGKAYTLPQYKKHSKRPVQHKRRGHDHMCEHCGKAYTTHQFLKNHQMTHTGERPFKCDRCPKGFTTAVQLTWHTRTHTGERPFQCDQCHQAFSLEGNLRRHRKAAYSLGTHTGETPFQCDQCHQAFSLEGNLRRHRKAAFSLETHTGETPFQCDQCHQAFSLEGNLRRHRKAAYSLGTHTGETPCQCEQCHQAFSLEGNLRRHRNAVHLGLRKNVPCPRCEKTFSTNSTMKLHVRTVHDGAPWPRRDRRPRKQPPQITE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-