Basic Information

Insect: Cydia amplana
Gene Symbol: THAP3
Assembly: GCA_948474715.1
Location: OX419680.1:3873291-3894486[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.035 1.9 9.6 0.7 1 23 395 418 395 418 0.93

2 10 0.55 30 5.8 0.2 1 23 422 444 422 444 0.92

3 10 0.006 0.32 12.0 1.0 1 23 449 472 449 472 0.98

4 10 0.004 0.22 12.5 0.7 1 23 476 499 476 499 0.96

5 10 9.9 5.3e+02 1.9 0.1 2 21 512 531 512 532 0.85

6 10 0.14 7.5 7.7 0.2 2 23 585 607 584 607 0.96

7 10 0.013 0.73 10.9 0.5 2 20 623 641 622 644 0.92

8 10 2.7e-05 0.0015 19.4 2.5 1 23 650 672 650 672 0.99

9 10 0.00034 0.018 15.9 2.8 1 23 679 701 679 701 0.98

10 10 0.00011 0.0057 17.5 2.1 1 23 707 730 707 730 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.035	1.9	9.6	0.7	1	23	395	418	395	418	0.93
2	10	0.55	30	5.8	0.2	1	23	422	444	422	444	0.92
3	10	0.006	0.32	12.0	1.0	1	23	449	472	449	472	0.98
4	10	0.004	0.22	12.5	0.7	1	23	476	499	476	499	0.96
5	10	9.9	5.3e+02	1.9	0.1	2	21	512	531	512	532	0.85
6	10	0.14	7.5	7.7	0.2	2	23	585	607	584	607	0.96
7	10	0.013	0.73	10.9	0.5	2	20	623	641	622	644	0.92
8	10	2.7e-05	0.0015	19.4	2.5	1	23	650	672	650	672	0.99
9	10	0.00034	0.018	15.9	2.8	1	23	679	701	679	701	0.98
10	10	0.00011	0.0057	17.5	2.1	1	23	707	730	707	730	0.93

Sequence Information

Coding Sequence: ATGCGGTGCAGTGTGCAAAACTGTTGCAACGATACGAAACGAACAACCAAAAGCCATGGGATTACATTTCACTTGTTTCCCAAAGAGCCAAATCTCCGGAGTGCCTGGATGGAGGCACTAGGCATGTCAGACTGGGAGCCGAAGGACCGCAGCACGATATGCTCGGAGCACTTCCGGAATGATGACTTTTATGAGACCAGGTGTGGGTTACGGAAGATCAAGAATGGAGCTGTGCCTGTGTCTGCTCAGGATTTGGCCAATGATCTGGACGCACCAGCTGCTTTAAGGGTGTGCAGGATATGCCTGGCAACGGACTGCAAGATGTACAACATACGGGATCACAAGCTGGAGCAGGCCTTCACAGAAGTCAGTGGGATGACAATGAGTGAGGAAGACAAATTGCCTCAGCGCGTCTGCTGGGAGTGCGGCCATCGACTGTTAACAGCTGCCAGGTTCCGGAGCAAAGTTCTTAGAGCGCATGACCTCCTTACTGGTCTTCCTCACGCCAGTCCATATATCACAATACGCGATATCCGGTCAATAAACCGACGGCAAAACCAACTAAGATCTCACCTGACATACAAATATTATGATCCTAACGATTACCACATACACATAAATGATGATGAAATCATCGTCAAATCAGAAATCAAAGATACTGAAGATCTAGAACAAAAAGTACCGCCTATCGCTGAAGTAGAACTTGTAAAAGATGAAAAAAACAATACGGAATTATTTTATCAAGAATTTGATAATTATGATGATAATTTTGAATATAATAATGATGCAAGTTATGTGGAAGGTAACCAAGTGAATGAAGATAGTGACGATAAAGTGTTAAGTGAAGTGTATGTGAAGAAGAAGCGGAAAGTGAAGAAGGTTAAAGTGAAGAAGAAAGAGAAAGTAGTGAGGAAGAAAGAGGAGGAGGATAATCCAGTGACTACTATGGATAAATACAAAAACTCTGACGTCAAACGGCGCAAGACCACCGACGGGCTCGACGAGTCCCTCTTCACGATCACTACGCTCAGCTACGACGAGCAAATAGCCGAGATACAGAAACGACAGGAGAGCACCAACTACAAGAGCGCGCCGTACAAGTGCGCCGTGTGCTATAGAGGGTTCCTCGTACGGGACAGATATGATGCGCACGTCGTGAGGCATAGTGAGCAATCCGGAGCGTACGAGTGTTTCATATGCAAGAGTCGGTTGAAGAGCGCGCGAGCGCTGCGAAAACACCTCACAGCGCAACACACGGAGAAGTTCAGTTGTAAGGGCTGTCCGTTCGTCACCAGGAACAGGGGCGTCGCCCGAGAGCATGAAAAATGGCACGCTGGCACTAAGTACCAGTGCCCGCACTGTCCGAGCGAATTCGATAAGCTGACTACATACATGGGCCACATAAGGATAAAGCACGTGTCTGACTTCGTGTGCGAGCTGTGCGGGTACACGTTCGTCAGCAAGAAGGGCATCGACGTTCATAAGAAAAAGAAACACCGGCTGCAGGACAAGACGGTAGAATTAGAAGGCCCGTACTGCGAGACGTGCGAAGTTCGTTTCGTGTCAGAGGAGGCCCACGCGCGACATCTCAAGCTGTCGTCGCGACATAGCAGCGATAGCGACCCCAATCGCATCCGTAACGACTCGCAGAGCATCAACGCGGAGAAGAACGGTCGAGTGGTGCGGAGAGTTGAGAGGAGACCTGTCATACACGCGCGCGACGGAGAGAGACAGGACACCGCCGGACCCGTCACCTGCGAACAGTGTGGCATCCAACTACGTGACTTGAGACTGTACGCCCAGCACTTCCGACGCGCGCACCCGGACAAGAATCGAACCAAATACCCCGCGATGAAAACACCCTGCATGTGCGAGCAGTGCGGACGCATCTTCCAGAGTATGGCCCTCCTAAAAGACCACATGTGGGTGCACACCGGTGAGAAACGTTTCAAGTGCGACCGCTGCGAGAAGAGCTTCACCCAGAAGACGAACCTGGTGTTCCACATGCGGGTCCACAGCGCCACGCGGCCCAGCTACGAGTGCCCCCTGTGCGGGAAGCACTTCGCCTTCTTCAATAACCGGCGGAGGCATATGTTTATCCACACCGGCCTAAAACCATACAAGTGCGAAACATGCGGCAAATGCTTCACCACCGCCGGCGAGCAGCGCGCGCACGTAGAGCACGTGCACCTGAAGAAGCCGTGGCCGAAACGTCAGAGGCACCGGGAGGCCGAGCCCGCGCCCTGGCAGAAATGTCTTGACCCTATGGAAGACTAG
Protein Sequence: MRCSVQNCCNDTKRTTKSHGITFHLFPKEPNLRSAWMEALGMSDWEPKDRSTICSEHFRNDDFYETRCGLRKIKNGAVPVSAQDLANDLDAPAALRVCRICLATDCKMYNIRDHKLEQAFTEVSGMTMSEEDKLPQRVCWECGHRLLTAARFRSKVLRAHDLLTGLPHASPYITIRDIRSINRRQNQLRSHLTYKYYDPNDYHIHINDDEIIVKSEIKDTEDLEQKVPPIAEVELVKDEKNNTELFYQEFDNYDDNFEYNNDASYVEGNQVNEDSDDKVLSEVYVKKKRKVKKVKVKKKEKVVRKKEEEDNPVTTMDKYKNSDVKRRKTTDGLDESLFTITTLSYDEQIAEIQKRQESTNYKSAPYKCAVCYRGFLVRDRYDAHVVRHSEQSGAYECFICKSRLKSARALRKHLTAQHTEKFSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCPSEFDKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLQDKTVELEGPYCETCEVRFVSEEAHARHLKLSSRHSSDSDPNRIRNDSQSINAEKNGRVVRRVERRPVIHARDGERQDTAGPVTCEQCGIQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCDRCEKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPYKCETCGKCFTTAGEQRAHVEHVHLKKPWPKRQRHREAEPAPWQKCLDPMED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00325875;
90% Identity: iTF_00412020;
80% Identity: iTF_00409348;