Basic Information

Insect: Cydia amplana
Gene Symbol: Bcl11a
Assembly: GCA_948474715.1
Location: OX419679.1:5387546-5391791[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.22 12 7.1 4.7 1 15 175 189 175 200 0.78

2 15 4.4e-06 0.00024 21.9 2.4 1 23 206 228 206 228 0.96

3 15 3.9e-06 0.00021 22.0 0.5 1 23 234 256 234 256 0.98

4 15 5e-06 0.00027 21.7 5.3 1 23 262 284 262 284 0.98

5 15 0.0015 0.081 13.9 1.3 1 23 319 341 319 341 0.97

6 15 0.00066 0.036 15.0 2.2 1 23 347 369 347 369 0.93

7 15 0.0012 0.066 14.2 5.6 1 23 375 397 375 397 0.97

8 15 2.5e-05 0.0014 19.5 0.2 1 23 403 425 403 425 0.98

9 15 0.00044 0.024 15.6 3.8 1 23 431 454 431 454 0.96

10 15 1e-05 0.00055 20.7 1.1 1 23 462 484 462 484 0.97

11 15 0.00036 0.02 15.8 0.8 1 23 501 523 501 523 0.97

12 15 3.6e-06 0.00019 22.1 4.4 1 23 529 551 529 551 0.98

13 15 9.6e-06 0.00052 20.8 1.7 1 23 557 580 557 580 0.96

14 15 0.00026 0.014 16.3 0.1 1 23 586 608 586 608 0.96

15 15 0.0034 0.19 12.7 3.3 1 23 614 637 614 638 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.22	12	7.1	4.7	1	15	175	189	175	200	0.78
2	15	4.4e-06	0.00024	21.9	2.4	1	23	206	228	206	228	0.96
3	15	3.9e-06	0.00021	22.0	0.5	1	23	234	256	234	256	0.98
4	15	5e-06	0.00027	21.7	5.3	1	23	262	284	262	284	0.98
5	15	0.0015	0.081	13.9	1.3	1	23	319	341	319	341	0.97
6	15	0.00066	0.036	15.0	2.2	1	23	347	369	347	369	0.93
7	15	0.0012	0.066	14.2	5.6	1	23	375	397	375	397	0.97
8	15	2.5e-05	0.0014	19.5	0.2	1	23	403	425	403	425	0.98
9	15	0.00044	0.024	15.6	3.8	1	23	431	454	431	454	0.96
10	15	1e-05	0.00055	20.7	1.1	1	23	462	484	462	484	0.97
11	15	0.00036	0.02	15.8	0.8	1	23	501	523	501	523	0.97
12	15	3.6e-06	0.00019	22.1	4.4	1	23	529	551	529	551	0.98
13	15	9.6e-06	0.00052	20.8	1.7	1	23	557	580	557	580	0.96
14	15	0.00026	0.014	16.3	0.1	1	23	586	608	586	608	0.96
15	15	0.0034	0.19	12.7	3.3	1	23	614	637	614	638	0.95

Sequence Information

Coding Sequence: ATGGAGGAGTTACATTCGTGTAGCTGCTGCCTGGTACGGCCCCCGGAGAAGGGGCTCAAGACGCTGTATAAACATCTCGGCAAAACAGAAATATATTACGACATGCTAAAAGACTGCTTCGACATAAATCTTGGCATAGGGAATGAGGAGTGCGGGATCTGCGATGTGTGTGTGGGGCGGCTGCGGGAGGCGAGCGACTTCAAGCTGCAAGTGAAGCGCAGCCAGGCAGAATTGCAGGCACGGCTCAAGGGAGTAATCACTGCCAGTGACAAGTTCAAAATAAAGTTGGAGAAAGCTGCTGGAGATGAAAACATCATAGGTGACATCAAGCTGGAGAAGTCTGAGGTGGAGATGGCCGATGGCGAGGTCGTATCAGTGGCCATATACGGCGGAGCACCAGGGCCTTCAGCGGAACCCATTTCTACTGCGTCAAAACGAGTCACTTCCCCAGTGGACGAGCCTGACACCAACCCCGACGACTCCGATCCGGCTCCGGCTCTAAGCCGCGGCCGCGGTAAAGTACACACCTGCGACATATGCCAAAAAACATTCAAGAACCCTAATGCAAAAACCAGACTCATGATCCATCGCCGCTcccacactggggagaagccatacgcttgcaatgtatgcgataaaagattcatacaaaaaagtcatttaaatacacattacgcataccacatgggaaagtttaaattctcctgcgaagtatgcgacaggcgattcgtacaaaagaatgaatttgttatacatatgcggatacacacaggtgcaaaaccgttttcgtgtgatatatgcaacaaaaaatatagacagaaaagtcacttaacagttcataaaaagacacaTTTGAAATTTGATCATAGTCAAGTAGAGCCAGGAGAAATAACAGTATGTAAAACAGAGTTTGCAGATGAAACTAAAGATCAAGTATCCGCAGACCAGCAAATATTCACTTGTGATATATGCAAAAAACAATTTGCAGAAGAAAGCACCTTTTACGCTCATAAAAATAATCATTCCGGGGATTACCCATTCACTTGCGATGTTTGTGAAAGGAAATTCAACACGCAGTTTGCGTTGAAAAATCATAAATTCGATcacaccggagggaaaccttacaagtgtgataaatgcaataaaagatatacatcaaaatgtgctttaaaactacattcaaaacttcatgatgaggattataagtacgcgtgtgttgtatgtaacaaacgattcataaaaaaagacgcgttgagtatacacctgcgcgtacacacgggagaaaagccttataactgtgaaatatgtcaaatgaagtttcgcTATAGATGTAGCTTAAAGAGACATCTATTAGTCCAACACAACCAGGTTATGGACAAACAATTCTGTTGCGATATTTGTGGAAAGCGATTTGCACTACAGGGGACTCTAGCTAAACATATGGATAGACATGCCGAGAAAGAAATGGAAGATAAAGCATTAAGGGAAGGAAGAAAGGAGTATATGTGTGAAATATGTAGCAAACGATTTTCAACAAAAGGTATCCTAAGAAATCACAGTATAACACACTCTGATGAAAAACCTTTTGAGTGTGAAACTTGTCATAAGAAATTTCGGAAGAAGAGAAATTTGCAGGACCACATGATGGTGCATGAGGACTTTAAACAACACGCGTGCGAAGTGTGCGGCCAGCAATTTAGGCACAAATCTGCCTTGACAGTTCATGTTCGAAGAGTTCACTCAACTGTCAAGCCACATGCTTGTGATGTTTGTAAAAAGGCTTTTCCAGTACTTGCTGCATTGAAAGAACACTACCGTGTTCACACTGGGGAAAGACCATATGCTTGCGAAATATGCTACAAGAAATTTCAGCGTCATAGTGGAGTTAAGAAACATCTTATAAGCGTTCACCATGAGAAACCTACTAGATTTATTAAATTAAGAAACATGAATAATTATAACTAA
Protein Sequence: MEELHSCSCCLVRPPEKGLKTLYKHLGKTEIYYDMLKDCFDINLGIGNEECGICDVCVGRLREASDFKLQVKRSQAELQARLKGVITASDKFKIKLEKAAGDENIIGDIKLEKSEVEMADGEVVSVAIYGGAPGPSAEPISTASKRVTSPVDEPDTNPDDSDPAPALSRGRGKVHTCDICQKTFKNPNAKTRLMIHRRSHTGEKPYACNVCDKRFIQKSHLNTHYAYHMGKFKFSCEVCDRRFVQKNEFVIHMRIHTGAKPFSCDICNKKYRQKSHLTVHKKTHLKFDHSQVEPGEITVCKTEFADETKDQVSADQQIFTCDICKKQFAEESTFYAHKNNHSGDYPFTCDVCERKFNTQFALKNHKFDHTGGKPYKCDKCNKRYTSKCALKLHSKLHDEDYKYACVVCNKRFIKKDALSIHLRVHTGEKPYNCEICQMKFRYRCSLKRHLLVQHNQVMDKQFCCDICGKRFALQGTLAKHMDRHAEKEMEDKALREGRKEYMCEICSKRFSTKGILRNHSITHSDEKPFECETCHKKFRKKRNLQDHMMVHEDFKQHACEVCGQQFRHKSALTVHVRRVHSTVKPHACDVCKKAFPVLAALKEHYRVHTGERPYACEICYKKFQRHSGVKKHLISVHHEKPTRFIKLRNMNNYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00871555; iTF_00410542;
90% Identity: iTF_00410542;
80% Identity: -