Ctho025204.2
Basic Information
- Insect
- Cyclargus thomasi
- Gene Symbol
- -
- Assembly
- GCA_026546445.1
- Location
- JAOTAV010005703.1:302-4716[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.042 3 8.8 5.6 3 23 233 254 220 254 0.95 2 10 0.24 17 6.4 0.2 3 23 277 298 275 298 0.90 3 10 0.0017 0.13 13.1 0.4 2 23 321 342 320 342 0.96 4 10 0.0005 0.036 14.9 0.2 1 23 346 368 346 368 0.98 5 10 0.0001 0.0072 17.0 0.1 1 23 373 396 373 396 0.92 6 10 2.7 2e+02 3.1 0.1 2 20 403 421 402 425 0.79 7 10 6.7e-05 0.0048 17.6 0.7 1 23 432 455 432 455 0.97 8 10 0.00012 0.0085 16.8 1.2 1 23 461 483 461 483 0.94 9 10 5.6e-07 4e-05 24.1 1.1 1 23 489 511 489 511 0.98 10 10 1.8e-05 0.0013 19.4 3.6 1 23 517 540 517 540 0.98
Sequence Information
- Coding Sequence
- ATGACAACTAAAAGAAAAGGTCCAATAATAGACCCAGGGATATGTCGATGTTGTGGATCGTTAAAGAAATGCCGATTATTAAATTATGAGTATGAAAACTCTACTTTTAAGGAAATATATTCGGACATGTTCATGGAGTGCTTTGGTTTATTGTTGTCACATTTGGATGGCAAGCCCACTGACAGATTGGTGTGTGCAACTTGTGTACAGCGACTTAGAGAGGCTTGTAGCTTCCGACAACAAGTCATAAAGTGTGAAGAAATATTTGTAAAAGCTAAAGTTTATACTAGGGATGAAAAAGTGGTACAAAACAAAATTGAAACAGAAGATTTACTGTCTCCTATAGAGATACCTTTAATACAAACAACAATAAAGATTGAGAAACAAGAGTATATGATCATCAATGAAAGTTCTCCTGGCCCACCCTTCCCATTGTCGGATGATGACTCACAGTGTGATGACATTGGCATGGGTAAGGCACATGCAATGGGCATATGCATGTGTGGTGCGAACTCATTGGCATTCAGTTTTATTGTAGAAGATTGTTTCAAAAATAATCTACTTTTAGGAAGCATGCAAACAATACAGACAAAGATACGCGAGAAAGACGCATCGCATAAGACGGAATGgaacattcagattctagtcgagaactcctacgtctgccctttcaagtgtcgccacaactatctgctgtgctactactgcgggcaacattttaccgacatagaaacgctgaaggaccacacggaacgaatccacgacccgaagaaattcaaactgatcgactataagaatatgctcaaaatcgaactcacgagaatcgactgcagactctgcgacgaaaaaatcgatagcttggatcagttcaagcgacacgtcagcgacgtccacgccaagaaatactacttcaaccaccgggattccgtcctaccgttcaagttcaccaaggccgtggtgaggtgtgcgctgtgcgaggcggtgttcccctacttccatgccctaaacaaacatatgaaccagcacttcagtaattacgtgtgtgagcagtgcgggatgggtttcgtcgaccgaggccggttcgtgatgcaccagcagaagcacgagaccaccgagtatccttgtccgacctgtgggaaggtcttcaagtcggcttacaatcgagatctgcacgttgacaggatacataataaaaaagGTAGGgtgtattgtcccaagtgcgatgagatgctgatgtcgtacccgcagaagttgaagcacctggtggaggtgcacggagaagcgccgctcaccttcccctgcggcgtctgcgacaagaccttcgacaccaggcgcagcgtcacgctgcataagcggaaggtgcacttgaaggATTACAGATATGAATGCCAAACGtgcgggcagcgtttcttcacgcgtttcgcgctcaccaaccacatgccaacgcacaccggcgagaggaacttcagctgcaagatctgcgggaagtcctaccctcgcctcaagaccctcaagtaccacatcaggatacacactaacgacagaaggtacagatgccacgtgtgcgggcaggcgttcatacagaactgcagcctgaaggggcacatgaagagccaacatcctgagtatagttaG
- Protein Sequence
- MTTKRKGPIIDPGICRCCGSLKKCRLLNYEYENSTFKEIYSDMFMECFGLLLSHLDGKPTDRLVCATCVQRLREACSFRQQVIKCEEIFVKAKVYTRDEKVVQNKIETEDLLSPIEIPLIQTTIKIEKQEYMIINESSPGPPFPLSDDDSQCDDIGMGKAHAMGICMCGANSLAFSFIVEDCFKNNLLLGSMQTIQTKIREKDASHKTEWNIQILVENSYVCPFKCRHNYLLCYYCGQHFTDIETLKDHTERIHDPKKFKLIDYKNMLKIELTRIDCRLCDEKIDSLDQFKRHVSDVHAKKYYFNHRDSVLPFKFTKAVVRCALCEAVFPYFHALNKHMNQHFSNYVCEQCGMGFVDRGRFVMHQQKHETTEYPCPTCGKVFKSAYNRDLHVDRIHNKKGRVYCPKCDEMLMSYPQKLKHLVEVHGEAPLTFPCGVCDKTFDTRRSVTLHKRKVHLKDYRYECQTCGQRFFTRFALTNHMPTHTGERNFSCKICGKSYPRLKTLKYHIRIHTNDRRYRCHVCGQAFIQNCSLKGHMKSQHPEYS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00404103;
- 90% Identity
- -
- 80% Identity
- -