Ctho004732.1
Basic Information
- Insect
- Cyclargus thomasi
- Gene Symbol
- -
- Assembly
- GCA_026546445.1
- Location
- JAOTAV010028732.1:4500-15330[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00038 0.027 15.2 0.2 2 23 136 157 135 157 0.93 2 11 0.00013 0.0094 16.7 0.2 1 23 163 185 163 185 0.96 3 11 0.00031 0.022 15.5 0.1 1 23 282 304 282 304 0.98 4 11 0.3 21 6.1 0.4 2 23 311 333 310 333 0.94 5 11 0.0014 0.1 13.5 0.0 3 23 379 400 377 400 0.90 6 11 0.03 2.1 9.3 0.1 1 23 416 438 416 438 0.96 7 11 7.8e-06 0.00056 20.5 0.2 1 23 467 489 467 489 0.98 8 11 0.00059 0.042 14.6 0.2 1 23 495 517 495 517 0.97 9 11 0.00033 0.024 15.4 0.3 1 23 523 545 523 546 0.95 10 11 0.0065 0.46 11.4 0.5 1 23 559 581 559 581 0.96 11 11 0.002 0.14 13.0 0.1 1 20 740 759 740 762 0.93
Sequence Information
- Coding Sequence
- ATGGAAGGAGAGGATTTCAAGTTGCAGTGGGAGGAGGATGATAAGCCGAACATGGTAGTGACTGAAGAAGTGATATGTGGTTTGGAGAATGTACAAAATGTGTCCTACACGAATATGACGGCCGAAGAACTAATGGCACACCCTCATCAGACTGCAGCAGAGAATTTGATGTATTTATCCCAAGATGTGGTCTACACAGACAATGCACATTTAGTTGAAGACCCCAATGTAGAGTGTGTGACGGAGGAGGTCATAACTGATGACTGGGTCCTAGCTGGAGGCCAAGAGAGGGTGGAAGTGCCTTTGGAACAGCTGACTCATCCTGTGTCAGAAGTAAAAATAGAAAATGATGTTGATGTGCCACTTCCTACGGATCAGGATGAGTACACAGCTATGCGTCCATGGCCGTGCGACTTCTGCTCCCGTCGGTTCCGCAAGAAGGCAGCCCTGATGAACCACATGGTGGCGCACCAGAGCGACCGGCCCCACGCGTGCAACCTGTGTGGGGTGCGATACGTCCGCAAACCTGACCTCATGGCCCACCTCAAGGTGCATGCTTACCAGCCCGACAACATGACCTTTGTGGAAGATGGTGTCATAGATAATTCGTTACTAAAACCAAGGAAAAAACGTGGACGCCGGAAAAAGGCGCCCCCACCACCAGAGGACGACAGTTGGGAGAACATGACGTCAGCGCGCACGCAGCAGTGGTCGCGCCGCGTACGCACCCCGCCCAAGCCGCTACCGCCGCCGTCCCCGTGTTCGCCGTCACCGCGTTCGCCGTCACCGCCGCCGCTGCCGGCACGGTCACCGTCGCCGCCGCCCGCGGATCCGGCGCGACCGTTCGTCTGCCGTCAGTGCGGCGTCGGCTTCGCGAGGGAGAAGGCGCTGCAAAGTCACTCGAGGATCCACGGCGGCGACTCGCCCATAGAGTGCAGCGTGTGCGGCGAGCTGTGTTGGTCGCGTGACGCGCTGCGGTCGCACACGCGAGCGCGACACCCCGACATGCCGGCGCGCACCGAACCCCCGCCGCAGGACTTTGGCGACACAGACTCTGACGACGACATGGAGTACCAGATGTCGCCGGTCGCGGCAGCAGAGAGCCGCGATAACGTTCGCGGCCCAGAGCTGTTCTGCGGCGAGTGCGGCGTCGCCTTCCAGCGCGCCGACCTGCTGCGACGACATGTCGCCGCTGCACACAGCTACAAGCGGCAGCAGCACGACAGCAGCGGCACGTGGGAGCAGCACACGTGCGATGTGTGCGGGGAGGCGTGCGGGGACGCACTCACGCTGCTCGCGCACGCGGAGAGACACGCCGAGCGACCCCGGGCCGCGCAtaaGCTAAAAAAAATGTCTCGTGGACGTCACACGACGACATCAGCTTCCGGCATCAGACAGTTTCCGTGTAAAGAATGCGGTAAGGTGTTTGGTTCGCGCAGCTCGCAACAAATCCACGTGCGCATCCACACGGGCGAGCGGCCGTACGCGTGTCGATTCTGCTGGAAGGCGTTCGCGGATGGCGGCACGCTAAGGAAACACGAGCGTATACATACCGGTGAGAAGCCGTACGCGTGCGCTGTGTGCCCGCGCGCGTTCAACCAGCGTGTAGTACTGCGGGAACACGTCCGCAGCCATCACTCCGCACCCGACCGACGCGCATACGGTGGATATCAGTATTGTTGCTCTGTGTGCGGCAAACCAATGAACTCTAGTCAGGAGCTAGTTCAACATCTAATACAGCACTGCGACGAAAACACAGCCATGAAAAGACAACCCCAGAACGGGCCTAGAAAATACAAACGTCGACGGAAGCTAAAAACGGACGAGTCGCCGCCGGCGCGGTGGCGGGCCCAGTCGGAGTCGCCGGCGCAGTCGCCATTACGGCCGCCGTCACCTTCACCGCCGCCGTCTCCGTTACCGTCACCGTCCCCGCCGCCGCGCCGCCGCCGACGACGCCGCGTACCGCCGCCCCGGCCCCGCATGATTCATACAGAGGAACCCCGACCGCGCACTAAACAGGTGCGCGGTCGCCGCCCACCACGACACCCTGCGGACGACCTACTCGCGATCGGGCCACATTCGCCGTCGCCGCCGCCGGCAGCGTCGCCGTCGTCGTCGCCGGTGCGCGACAAGACGCCGACGTCGCCGCCACCGTCACCAGTGCGCGTTAAGTCGGCTTCGCCGTTGCCGTCACCGTCACCAACACTCGAGGGACCGTTCAAGTGCGAGATGTGCTCGGAGATGTTCCCGCGGCGGGACGCCCTTCTCCTACACGTTCCCGTACACATATGA
- Protein Sequence
- MEGEDFKLQWEEDDKPNMVVTEEVICGLENVQNVSYTNMTAEELMAHPHQTAAENLMYLSQDVVYTDNAHLVEDPNVECVTEEVITDDWVLAGGQERVEVPLEQLTHPVSEVKIENDVDVPLPTDQDEYTAMRPWPCDFCSRRFRKKAALMNHMVAHQSDRPHACNLCGVRYVRKPDLMAHLKVHAYQPDNMTFVEDGVIDNSLLKPRKKRGRRKKAPPPPEDDSWENMTSARTQQWSRRVRTPPKPLPPPSPCSPSPRSPSPPPLPARSPSPPPADPARPFVCRQCGVGFAREKALQSHSRIHGGDSPIECSVCGELCWSRDALRSHTRARHPDMPARTEPPPQDFGDTDSDDDMEYQMSPVAAAESRDNVRGPELFCGECGVAFQRADLLRRHVAAAHSYKRQQHDSSGTWEQHTCDVCGEACGDALTLLAHAERHAERPRAAHKLKKMSRGRHTTTSASGIRQFPCKECGKVFGSRSSQQIHVRIHTGERPYACRFCWKAFADGGTLRKHERIHTGEKPYACAVCPRAFNQRVVLREHVRSHHSAPDRRAYGGYQYCCSVCGKPMNSSQELVQHLIQHCDENTAMKRQPQNGPRKYKRRRKLKTDESPPARWRAQSESPAQSPLRPPSPSPPPSPLPSPSPPPRRRRRRRVPPPRPRMIHTEEPRPRTKQVRGRRPPRHPADDLLAIGPHSPSPPPAASPSSSPVRDKTPTSPPPSPVRVKSASPLPSPSPTLEGPFKCEMCSEMFPRRDALLLHVPVHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00935068;
- 90% Identity
- iTF_00744994;
- 80% Identity
- -