Ctho000521.1
Basic Information
- Insect
- Cyclargus thomasi
- Gene Symbol
- -
- Assembly
- GCA_026546445.1
- Location
- JAOTAV010014733.1:18737-24664[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.6 43 5.2 0.0 1 23 174 196 174 196 0.94 2 12 1.4 99 4.0 1.7 1 23 203 225 203 225 0.96 3 12 0.0055 0.39 11.6 0.0 1 23 229 252 229 252 0.97 4 12 3.6e-07 2.6e-05 24.7 1.0 1 23 257 280 257 280 0.94 5 12 0.0005 0.036 14.8 1.6 1 23 286 308 286 308 0.98 6 12 8.6e-09 6.2e-07 29.9 1.1 2 23 321 342 320 342 0.97 7 12 0.097 6.9 7.7 0.4 2 20 348 366 347 370 0.87 8 12 0.0096 0.69 10.8 3.3 3 23 381 402 379 402 0.96 9 12 0.025 1.8 9.5 1.2 1 23 409 432 409 432 0.95 10 12 0.00019 0.013 16.2 2.3 5 23 442 460 440 461 0.94 11 12 1.7e-06 0.00012 22.6 0.4 3 23 472 492 471 492 0.97 12 12 3.7e-06 0.00027 21.6 1.1 1 23 497 520 497 520 0.97
Sequence Information
- Coding Sequence
- ATGGCAGATGTACAAGTTAAAATAGAACCACGGGATCCAGAAGACGAACAGGATGAACCACAAGATCTTACAACTTCGGGACCAAGCTTTCTTAATTTTGTCAACCTCAAGCCTGAACCTTTTGACATCAAAACAGAGCCAGCTAGTGACCATGAGAACCAGTCAAGTGATGATGAAGCCCTTTTGTCTCATACCCAGATAAAGATTGAACCTTGCAGTGATAGCGGTACAGATGATGATGATGATGATGATGATTTCATGGCACCGGAGAGATCTAAACCTAGGAAGCGTAAGGATTCGTCAGACGAAGACTTTACGTTGGCCAGATACAAGAAAAAATTAAATAAAAAGAAAGGGGAGGCTGGCAATATAAAGCCAAGTATGAAAGGAAGATCTAAAGCTGGGCCAGAAATGATATACAAGGATGAAATAATAAGCAAGATAGAGATTGAGACAATAACAGAGGAAGACCGGCAGAATGAACATCAGGAGGTCTTGGAGACTCGGAGGCATATGAGGTTCCTTTGTGAGTGGTGCGCTGTTGGCTTCGTGATTGAAGAAGCTTACCAAGTACACATGAAACTGCATACCCAGGAGAACGGCACCCACGAGTGCGAGCTGTGCCACATGTGGGTGCGCAACGCCGACGTTCTATACCGTCACCGGTTGCGGCACTACCGCCGGTACCGGTGCGTCGTGTGCGGCCTGCGACTGCGGGACAAGGACACCGCCGCCGCGCACATCATGAGCGACCACCAGGGCACCTCGTTCCCCTGCCCGCACTGCGACAAGGGGTTCAAACGGCCTCAATATCTCCGACGTCACATAGCGCAGATGCACACGCGGGCGACCGAGTACAAGTGCCCCGTCTGCGGGCGCGTCTTCTACGAGCGCGGGTGGTTCCGGTGTCATGTCAGATCCCACAACGAGGAAGTCCAGATGTGCGCGTCGCAGAGCCTCCCGTGCACGCAGTGCGGGCGCGTGTTCCGCCAGCGGTCGAACCTCAAGCGGCACATGTTGACGCACGTGCACGAGCCGGTGCCGTGCCCGCACTGTGACGTCACCGCCGACAACCCCGAGTTGCTGCGCGTGCACTGCCTCAAGATGCACCCCGAACTCGTCGGGGATGCGGACACGATATGCGTGCACTGCGGGCGCGCGTGCGCCACCATACCGATGCTGCACCGACACTTGAGACGAATGCACGCTGACAGGACCAAAAGGTTCGAGTGCGACCACTGCTCCCGTCGCTACCTCACGAAGGGCGAGGTGAGGTCGCACATAATGTGGTCCCACCTCCGGCGGCTCGGCGGGCACGCGTGCGAGTGCGGGCGCGTGTTCCGCAACCCCGCGCGCCTGCGGCACCACCAGCGAGTCCACCACCTGCGCCTCACGGAGCCGCGCGACAAACACTGCCCGATCTGCGGCAAGGCCTTCGCGAACCAGCAAGTCCTTACTCGTCACATACGCGGTCACAGCGGCACCACGTATCCGTGCCAGGAGTGTGGGCAGACCTTCAAAACGCAGTCCTACGTCAAGGTGCACTACAAGATCAAGCACTTAAATATGACGCGGGCGCAGGTGAAAGCGGAGAGCAAACGGAAACTCCTCATGGTGGACAACGTGGACGACCCCCCGAAGTTCCGGCGGCCCCCCTCCCCGCGACCCCCCGAACACCCCCCGGATCTGCCGACCCTCGCCTTCGCGGACGTGGGGGGCATCAAGCAGGAGGTCATTGAGGTGCCGAAGTTCGAGACCTTCATAGATATACCACGGTAA
- Protein Sequence
- MADVQVKIEPRDPEDEQDEPQDLTTSGPSFLNFVNLKPEPFDIKTEPASDHENQSSDDEALLSHTQIKIEPCSDSGTDDDDDDDDFMAPERSKPRKRKDSSDEDFTLARYKKKLNKKKGEAGNIKPSMKGRSKAGPEMIYKDEIISKIEIETITEEDRQNEHQEVLETRRHMRFLCEWCAVGFVIEEAYQVHMKLHTQENGTHECELCHMWVRNADVLYRHRLRHYRRYRCVVCGLRLRDKDTAAAHIMSDHQGTSFPCPHCDKGFKRPQYLRRHIAQMHTRATEYKCPVCGRVFYERGWFRCHVRSHNEEVQMCASQSLPCTQCGRVFRQRSNLKRHMLTHVHEPVPCPHCDVTADNPELLRVHCLKMHPELVGDADTICVHCGRACATIPMLHRHLRRMHADRTKRFECDHCSRRYLTKGEVRSHIMWSHLRRLGGHACECGRVFRNPARLRHHQRVHHLRLTEPRDKHCPICGKAFANQQVLTRHIRGHSGTTYPCQECGQTFKTQSYVKVHYKIKHLNMTRAQVKAESKRKLLMVDNVDDPPKFRRPPSPRPPEHPPDLPTLAFADVGGIKQEVIEVPKFETFIDIPR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00164631;
- 90% Identity
- -
- 80% Identity
- -