Ctho007093.1
Basic Information
- Insect
- Cyclargus thomasi
- Gene Symbol
- ZFY
- Assembly
- GCA_026546445.1
- Location
- JAOTAV010041924.1:10993-13839[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00012 0.0084 16.8 2.4 1 23 163 186 163 186 0.97 2 19 4.6e-05 0.0033 18.1 0.4 1 23 195 218 195 218 0.96 3 19 0.017 1.2 10.0 0.6 2 23 231 253 230 253 0.97 4 19 0.00092 0.066 14.0 1.9 1 23 262 285 262 285 0.96 5 19 0.00012 0.0085 16.8 2.5 1 23 296 318 296 319 0.95 6 19 1.7e-05 0.0012 19.5 2.6 1 23 341 364 341 364 0.98 7 19 1.1e-05 0.00077 20.1 1.8 2 23 374 396 373 396 0.97 8 19 0.016 1.2 10.1 0.9 2 19 401 418 401 420 0.94 9 19 0.008 0.58 11.1 1.5 2 21 426 445 426 448 0.94 10 19 0.071 5.1 8.1 2.7 1 23 456 479 456 479 0.95 11 19 0.00031 0.022 15.5 3.6 1 23 484 507 484 507 0.96 12 19 0.0063 0.45 11.4 0.3 2 23 519 541 518 541 0.96 13 19 0.00015 0.011 16.5 1.2 1 23 562 585 562 585 0.97 14 19 0.031 2.2 9.2 0.2 2 23 592 613 591 613 0.94 15 19 0.0011 0.076 13.8 1.5 2 23 618 639 617 639 0.97 16 19 1.4 99 4.0 1.4 2 23 646 669 645 669 0.93 17 19 4.2 3e+02 2.5 0.8 1 23 676 698 676 698 0.84 18 19 0.012 0.83 10.6 0.1 1 23 705 727 705 727 0.97 19 19 2.5 1.8e+02 3.2 3.9 1 23 733 756 733 756 0.96
Sequence Information
- Coding Sequence
- ATGGAGGTTATGAATGAAAGTATTGATATAAAACTGGAGCCAGACGATGATGATGATCCTAGAAAGGATCCAACATCGTTCCTGCCTGAGGAACCAATGTCGTACGAAATAAAACCAAAAAAGAAGAAGAAAAAGAAAAAACAGATAGATCCCTTTGGTGATATTGAAGAGAGAGTCAAGTTGCCGACTCCGACAGTGTACGAGCCAGCCAGCGATGAAGTAGTGGAATACGTGCCAGCTACGGAAGTGATTTTGCCCACTGAAACTGGATACGAACCGGGTATTGCTATTAAAGTTGAAAATATTGAGGTTGAAGTTGATTATAATGATTTTGCCAATGTATCCATGCCGGATGATCCGCAAGGGGAAGGAAGCGAACTGATGGAGGTGAAGTTCGAACAGCAGAACAATGCCCTACATCCAATCTTTGATGAGATACTAGACAATACAAAGAAGATGATCCAAGAGAATACTTCAGCTCAGAACTTTGTATGTGAGATATGCCACCTTGTCTTCCGGAAGGAGAGAACATTGAGAGTGCACCAACAAAGGAAGCACAAGTTGCTGAAAACAGCATTCAAACACATCTGTGATGACTGCGGCATGTCTTATGAAGTTAAAAACAGTCTGATAGCTCACATCAGAAGAAAACACGGTCCTGGCGCAGAAATAGGCGATAGTGAAGAAAAAACTTGTGACATTTGCTATCTAGTCTTTAAAGGAATACCAAGACTCCGTATGCATATGCGTAGAAAGCATGGATCGTTTGAAGACTCGTTTGAGCACGCGTGCAAATACTGTGGTCTTACTTACGATAAATTGACTAGTCTGTCTGTGCATATAAAACGAAAACATTCCAAAGTTAAAACAACTGAAAACCAATGGTTCAGCTGTCCATTTTGTCCGAAAGTTTATACGAAACGTGAGACTTATGCAAGACATGTGCAGAGACATCATATTATCGATGAGAGGCTTAACCAGGATATGTTGAACGCTATGGTGGATGAGAACTCAGGGGAATTCACTTGCAGTGAGTGTAAACTAGTGTTTTCCACTTTTAACTCCCTAAAACTACACATGAGAAGGAAACATAATGCATTTACGGAGAAATTTAGACTTAAATGCAAGCTTTGCGGTCTATCCTATGATAAAAAAGAAAGTTTGAAGAGACATATACGAAGGAAACATGACCAGGGTGCTTACTGCGAGGTCTGCAATAAGCAGTTTGTTACAAGAGAACAGTACTTAAACCATTCACATGAGAAGACCATTAATGAGTGTCATTTGTGTAACTTTATATTCGCCTCTCCGGGAGGGCTAGCTAAGCACTTGCGTTGCACTCACAATAAGGACTCGCCGAAAAAGTACTTCTGTAGTACGTGCAACGAAGGATTCCATGATAAGAGGCAGCTGAAGCCACATTACTTGAAGGTGCATTTAAAAGTATCCTACACATGTCGCTATTGCAACAAGATATTTAAAGCCAGAGAGAGTTTCAAGCGACATGTGCGTTTCCAACATCAAGTTAAAGAAGAACATACCTTGAACGGTCAAAAGTGTGACCAGTGCGCTGAAGTATTTGTCGATGAATTAGAATTGTGTCGCCATGTCAAAATCGCGCATGGCAATGAAGATAATTTGGAAAAAACACAGGTCAAAACTGAAGAATTAGAAAAACAAATGCACCAGTGCCCAAAGTGCACGGAAAGTTTTGAAGTATTTGAAGAATTGAGAGCACATTATAATACAAGTCATCAGATAGTTGAAGAGACTCAATGCCAGATTTGCGGTGAAATGGTTATGTCGAATGACCTACAGAAGCATATAAAGGCCAGTCACGAAGAAACATTGACATGTACATACTGTGATTTCGAGACCAACAGCAAAACAAGTTTGACTCAACACTTATTACGGCACAAAAATGCTAAAACCTTAACTTGTGATTTCCCGAATTGCAAATACAACTCATACTACGAAAGCGCTATGAAAAAGCATAAGCAGAAACATAGTGAGCAGGGTGTGAAATTCCAATGTACGCAATGTCCGTTCCAAACTATGAATAAATATATACTACGGTACCATGAGGAAGCCCATGCTACGGGGAAAAAGAGATATGTCTGCGACCAGTGTGACTACGCAACAATATTGCCAGCAAATCTGGTACAGCATAAATACAAGCATTCTTCAGAAAAGCGGTTTAGATGCGAGTTTTGTCAGTTTGCAACGAAGTATAATACCTCACTGCGTTTTCACGTTAAGAAAAAACATTGTGATCTCCCTACTTAG
- Protein Sequence
- MEVMNESIDIKLEPDDDDDPRKDPTSFLPEEPMSYEIKPKKKKKKKKQIDPFGDIEERVKLPTPTVYEPASDEVVEYVPATEVILPTETGYEPGIAIKVENIEVEVDYNDFANVSMPDDPQGEGSELMEVKFEQQNNALHPIFDEILDNTKKMIQENTSAQNFVCEICHLVFRKERTLRVHQQRKHKLLKTAFKHICDDCGMSYEVKNSLIAHIRRKHGPGAEIGDSEEKTCDICYLVFKGIPRLRMHMRRKHGSFEDSFEHACKYCGLTYDKLTSLSVHIKRKHSKVKTTENQWFSCPFCPKVYTKRETYARHVQRHHIIDERLNQDMLNAMVDENSGEFTCSECKLVFSTFNSLKLHMRRKHNAFTEKFRLKCKLCGLSYDKKESLKRHIRRKHDQGAYCEVCNKQFVTREQYLNHSHEKTINECHLCNFIFASPGGLAKHLRCTHNKDSPKKYFCSTCNEGFHDKRQLKPHYLKVHLKVSYTCRYCNKIFKARESFKRHVRFQHQVKEEHTLNGQKCDQCAEVFVDELELCRHVKIAHGNEDNLEKTQVKTEELEKQMHQCPKCTESFEVFEELRAHYNTSHQIVEETQCQICGEMVMSNDLQKHIKASHEETLTCTYCDFETNSKTSLTQHLLRHKNAKTLTCDFPNCKYNSYYESAMKKHKQKHSEQGVKFQCTQCPFQTMNKYILRYHEEAHATGKKRYVCDQCDYATILPANLVQHKYKHSSEKRFRCEFCQFATKYNTSLRFHVKKKHCDLPT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01248418;
- 90% Identity
- -
- 80% Identity
- -