Ctho022681.1
Basic Information
- Insect
- Cyclargus thomasi
- Gene Symbol
- -
- Assembly
- GCA_026546445.1
- Location
- JAOTAV010015703.1:8207-10603[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 1.9e-05 0.0014 19.3 4.0 1 23 14 37 14 37 0.95 2 19 0.0035 0.25 12.2 1.6 2 23 43 65 42 65 0.94 3 19 0.00012 0.0086 16.8 0.1 2 23 74 96 74 96 0.97 4 19 3.8e-05 0.0027 18.4 0.4 2 23 105 127 104 127 0.93 5 19 2.4e-05 0.0017 19.0 0.5 2 23 135 157 134 157 0.96 6 19 1.1e-06 8e-05 23.2 1.0 2 23 165 187 164 187 0.96 7 19 1.4e-05 0.00098 19.8 4.0 1 23 193 216 193 216 0.97 8 19 0.0049 0.35 11.7 0.2 3 23 261 282 260 282 0.95 9 19 0.027 2 9.4 2.3 1 23 312 335 312 335 0.94 10 19 0.069 4.9 8.1 0.4 2 21 343 362 342 363 0.93 11 19 0.029 2.1 9.3 0.6 3 23 373 394 372 394 0.95 12 19 0.017 1.2 10.0 3.2 1 23 417 440 417 440 0.97 13 19 3.8e-05 0.0028 18.4 0.5 2 23 447 469 446 469 0.97 14 19 1.9e-05 0.0014 19.3 3.1 2 23 476 498 475 498 0.92 15 19 0.034 2.5 9.1 1.3 1 23 504 527 504 527 0.91 16 19 0.12 8.9 7.3 2.7 2 23 535 557 535 557 0.96 17 19 0.092 6.6 7.7 0.0 1 23 564 587 564 587 0.91 18 19 0.0006 0.043 14.6 0.2 1 23 594 617 594 617 0.98 19 19 0.00082 0.059 14.2 2.3 5 23 633 652 630 652 0.91
Sequence Information
- Coding Sequence
- ATGTCAAGCAATGAAAACTCTTGTGACAAGCCCAAGGAGTACATTTGCGACTACTGCACCCGCACCTTCACGCGCTACTACAACCTGCAGACGCACATCGAGAACTGCCACCTCAACTCCTCATGCTGCTGCGAGATCTGCTACCAGAGCTTTGGGAGCCCGGCCGGCCTGCAGCAGCACCTTAGCCGCGGTCACAACCGCTTCGGCCAGGGGCTGCCGGAGTGCGACATATGCGGCAGGATATACGCCAGGAAGCAGAATATCGCCACCCACATGCTCACCACCCACCTGCTCAGCTACCGCCCTGAGATCCGCTGCGACCTCTGCTACAAAGTTTTCACCACCGAGCGTAACCTCCGCCGCCACGCCGCCATGCTTCACAACCCCGACTTCGCGTATCTCACCTGCGACACCTGCAAGAAGATCTTCAAGGGCAAGGATTCCCTGATCACTCACATCCAAACCGTGCACGCCCCGCTCAAGGATCTCATCAAATGTCAGGAGTGCGACAAAATCTACACCAACAAGAGAAATCTGAAACGTCACATCGAGATGAGTCACGAGAGGAGAGTCGAGTTCAAATGCTCGAGGTGCACGAAATCATACACTTCTAAGCAAAGTTTGAAACGACACCAGCAGAGCGTGCACTCGGAGAACCACGACGATCGCTCGTCTCAACTGTGTCCCACTTCAACTGAAGGCAAGGACGACACCAATTTATCGACAGAGATGGAGGAGTACGAGAGAAACGGTGAATCTCGACACAAAGATCAGGTTGCTTGTGAAACATGTTCTGCATCGTTTTATGAGGAAGCGCAGCTAAGAAAGCATATAAAAGAAACTCATACATTCCAAGACTTCTACAAATATTGTAAGAAAGTTCTCCTGCTGAGATCAAAAAACCAGACCACCGAAAGCGGAAACAAGAAGTGGCACTACTGCGATATGTGCTCGGAGTACTTCGCAACTGAGGTCGAGATGAAGCACCACATGGGGTCGAGGCATGGCAGAGCTTTCCAACCGTCCACGTGCAACGTTTGCTTCCGACGGTTCTATACGAGAGAGTCGATCGCCGAACACAGGAAGGTATGCATCCCACCCCCGGACGCCAACCCCTGCGCTCACTGCGACAGGCTGTTCACCGACGTTTCGAGTCTTGAATTTCACATTAAAATATTTCACCCGAGAGCGCAGATCGCAGACTCCAACGTCTCGTCGACGTTCGTGGAGGAGCCGGCCGAGACGGTTTTCAAATGCAGCCGCTGCGAGCGAGTGTACTACGCCGAGCGCTCCCTCCGACACCACATCAAATTGAAGCACACCCTGGACGAGGAGGTGCAGTGCCAGTTGTGCGGCCGGGTCTGCAGCAACGAGTACTACCTCGCGTCGCACATGAAAATAGTGCACAACGACGACGACTGGTCCAAGTGCAAGTACTGCGGGAAGCAGTTCAAAACTAAGAGGAACATACGCCGCCACATCGAGTTCACCCACCTCGGCCGGCAGAGGTACAAATGCATCGCCTGCGACACCCTGTTTAAGGAGAAGCGGAGTCTCCGGAAGCACGTGCGCATCAAGCACCCGAACTCCGACCTGTTCCCGCAGTGTCACATCTGCATGAAGCGGTTCGAGTCGGCCAAGTCGCGCAAGATCCACCTGAAGCTACTGCACTCGTTCAACGTGAGCACGTTCCCGTGCGGCGCGTGCACGATGTCGTTCGCATCGCAGGCGGCGCTCGACGAGCACCTGGCGGCCGAGCACCTCGCCGACAGCGAGATCTACAAGTGCGAGGACTGCGGTCTCGTCCTGGAGGGCCAGGCGATGTACGAGCGACACCGGCGCTCGCGGCACGCGGGGCCCGGTGGTGGACGTCCCGGCCGGCCGCCGCGCTGCATCCTCTGCGACAAAGACTTCAGCTCGCGGAAGACCCTGAAGAGGCACATCAAGAACTTCCACAAGGAGTTCGACGACGAGGAGCTGGCGAGCCTGTGTCGGGGGCGGCCCGCCGGCGTCGACTGCCCTGACTGCATCAAGAACTTCAGCGACGACTACTACTACGACGTGTGCCAGAAGATCGAGGGTTTGCCCGACGCGGTGGTGTTCAAGTGCGAGTTCTGCAAGGCCTCCTACGGCCGCTTCGAGTTCCTAGTTCTGCGGCACAAACAAAGCTTCGATATGAGCAGGAGCAGGAGCTACTTGAGCGAATTGTGCACGGCGGAGATGAGCGAGGAGTCGGGGCAGTCGGACGACGATGTGGGGCCCCCGCCGGCGCCGGACAGCGAGACGCCCATGGAGCCGGAGAGCACCACTGCTGATGTGAAAGTCGAGTCCTCTCAGATTCTCGATTGTGACATCAAGTCGGAGCCGCATTCCCCGAAGAGTTGTGATGTTGACTAA
- Protein Sequence
- MSSNENSCDKPKEYICDYCTRTFTRYYNLQTHIENCHLNSSCCCEICYQSFGSPAGLQQHLSRGHNRFGQGLPECDICGRIYARKQNIATHMLTTHLLSYRPEIRCDLCYKVFTTERNLRRHAAMLHNPDFAYLTCDTCKKIFKGKDSLITHIQTVHAPLKDLIKCQECDKIYTNKRNLKRHIEMSHERRVEFKCSRCTKSYTSKQSLKRHQQSVHSENHDDRSSQLCPTSTEGKDDTNLSTEMEEYERNGESRHKDQVACETCSASFYEEAQLRKHIKETHTFQDFYKYCKKVLLLRSKNQTTESGNKKWHYCDMCSEYFATEVEMKHHMGSRHGRAFQPSTCNVCFRRFYTRESIAEHRKVCIPPPDANPCAHCDRLFTDVSSLEFHIKIFHPRAQIADSNVSSTFVEEPAETVFKCSRCERVYYAERSLRHHIKLKHTLDEEVQCQLCGRVCSNEYYLASHMKIVHNDDDWSKCKYCGKQFKTKRNIRRHIEFTHLGRQRYKCIACDTLFKEKRSLRKHVRIKHPNSDLFPQCHICMKRFESAKSRKIHLKLLHSFNVSTFPCGACTMSFASQAALDEHLAAEHLADSEIYKCEDCGLVLEGQAMYERHRRSRHAGPGGGRPGRPPRCILCDKDFSSRKTLKRHIKNFHKEFDDEELASLCRGRPAGVDCPDCIKNFSDDYYYDVCQKIEGLPDAVVFKCEFCKASYGRFEFLVLRHKQSFDMSRSRSYLSELCTAEMSEESGQSDDDVGPPPAPDSETPMEPESTTADVKVESSQILDCDIKSEPHSPKSCDVD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00935020;
- 90% Identity
- -
- 80% Identity
- -