Basic Information

Gene Symbol
salm
Assembly
GCA_905187585.1
Location
LR994567.1:13929458-13939056[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.11 8.5 7.5 0.8 1 15 339 353 339 361 0.84
2 10 0.00016 0.012 16.5 3.2 1 23 368 391 368 391 0.96
3 10 0.15 11 7.1 2.9 1 23 422 445 422 445 0.97
4 10 0.0057 0.43 11.6 0.2 1 23 449 472 449 472 0.93
5 10 0.33 25 6.0 0.1 2 20 485 503 485 505 0.93
6 10 1.2 91 4.3 0.1 2 23 558 580 557 580 0.94
7 10 0.0031 0.23 12.4 2.5 2 23 596 617 595 617 0.96
8 10 6e-08 4.5e-06 27.2 0.7 1 23 623 645 623 645 0.99
9 10 0.22 17 6.6 6.8 1 23 652 675 652 675 0.98
10 10 0.00025 0.019 15.8 0.2 1 23 681 704 681 704 0.91

Sequence Information

Coding Sequence
ATGAGTTGTTGTATATTGACCTGTGTGAATAGTGAAGCATCCAGTGCACCATATGAAGATGTTACCTTTTACAAAATACCTACCGAGTATCACTGGAAGCAGCTATGGCTAGAAGCCATCGGCATACCTGAGTGGCAGCTACGGTCTAATAGTGAAGTATGTTCCGCACATTTCGGAGAGCTTGACTTTACAATTGCAGAGACTGGAGAAAAGATTCTTTTGGAAGGTGCTGTCCCCAGCCTATGTCTTACCTGCAGAGTGTGCCTGGGCATGGACCGAAGGATGTACCACATCAGGGACTACAACTTACATCATGCTTATGAGATGCTTCTCGGAATCATGGTAGAGACCGTTGATCGGCTGCCCAAGATGCTGTGCTGGGAGTGCACCAGCAAGTTAAACTCAATTAAAACATTTAAGGAGAAGGCACTTAGGACACATCTACTTTTATCTGAAAGACTAGCCAAAAACAATATACTAACAGTCAGTGATATAAAATCTATAAACAGAGTTAATTTTAATTTGAGTTCACATCTTACGCTGAAATACAACGAGCCAGATTCCTATGATGTGCACATAGACCACGACCAATTGGATATACTGCAGGAGATTAAAATAGAGTGTTGTAAGTTGACGGAGGAACCCAAGAATGAGGTAGAGGATGTGGACTTCAAGCTAGAAGACGGTGTGAAGGATGAGGTGAATCACAGTTTCAGTGACAGTGACGACATAGAACTCAGTGAGTTGAGGACTAAAAAAGTAAGAAAGCGCAAGGGAAAAGTGAAAAAGGAAGGGACAGAACCAAAGAGGAAAAAGCGGGTAAAGAAAGAAGAGGTTAAGGAAAAGGTAGAAGATGAGGATGAATTGGAAAAATTACAGCGTGGGACGGTGAAGCGGCGCGTGCGCAGCTACGATATCAGCGACAGCCACTTCGACACGCGGCCGCTCACGCTGGAGGAGCAGCTGGCGGAGCTGCAGGCGCGCGCGCGCTCCGCCTCATACCTCGCCGCGCCGTACAAGTGTGATGTGTGCTACAAGGGATTCAAGTCAGCAGACACGCATGGGCTACACGTGGTGCGGCATAGCGAGAAGTACGGCGAATTCGAGTGCTTCATCTGCAAGCGGCGGTTCAAGAACGCGCGGCACCTGCGCCTGCACGTGTCCAGCCTGCACACCGAGCAGTTCAGCTGCAAGGCCTGCGACTTCGTCACGAGATGCCGAGGCATAGCGATTGACCATCAGAAGTGGCACTCGGGCAACACATACGAGTGCCCGCATTGTCTGTCCAAATTCGGCAAATTCACGTCGTATATGTCGCATTTACGGATCAAGCATTCATCGCGGTTCGCCTGCGAGCTCTGCGGATACACGTTCGTCAGCAATCGCGGCGTAGAAATGCACAAGGCCAAGCGACACAAACTGCAGGACGCAAAGATGAAGCTGGAAGGTCCGTACTGCGAGGAGTGCAAGCTGCAGTTCGCCAACGACGAGGCGTACCTGCGGCACCTCACGCAATCCTCCGTACACAGCAGCGACAATGACCCTAACCGCATCCGCAACGACTGGGGCTGCAAGGAACAGCTGGGCGTGGTGCGGCGCACGCGCAAGCGGCGCGCGCCCGGCGTCGTCACGCACTGGGTGGAGAACACCGACAGACCCAAGCAGAACATACCGTGCGAACAGTGCGGCGAGCAAATGGACAGCTACCGGTCGTACGCGCAACACTTCCGCATGGCGCACCCCGGCCTCAACCGCACCAAGTTCTCGCGCGTCACCGGCGCCTGCATGTGCGAGCAGTGCGGCAAGATGTTCGCGTGCAAGGCGCTCCTGCTCGACCACATGATGTCTCACTCCGGCGAGAAGCGGTTCAAGTGTGAGACGTGCGACAAGGCGTTCACGAACAAGAACAACCTGGCCGTCCACCAGCGCGTTCACGGCGCGCAGGTCCCCACCTACCGCTGCCCGTACTGCGAGCGACAATTCCACTTCTACCAGAACTGCAACCGCCACGTGAAGACCGTGCACAAGGGCGTGAAGCAGTTCCAGTGCGAGATCTGCGGCAAGGAGTTCACGTCGGCGGCCGGCCAGCGCGCGCACGTCGACCACGTGCACCACAAGAAGCCCCGCCCCAAACGCGTACGCGCACGCGCACCACCCGCCCCGCCCACCGCCTACCGTGACTAA
Protein Sequence
MSCCILTCVNSEASSAPYEDVTFYKIPTEYHWKQLWLEAIGIPEWQLRSNSEVCSAHFGELDFTIAETGEKILLEGAVPSLCLTCRVCLGMDRRMYHIRDYNLHHAYEMLLGIMVETVDRLPKMLCWECTSKLNSIKTFKEKALRTHLLLSERLAKNNILTVSDIKSINRVNFNLSSHLTLKYNEPDSYDVHIDHDQLDILQEIKIECCKLTEEPKNEVEDVDFKLEDGVKDEVNHSFSDSDDIELSELRTKKVRKRKGKVKKEGTEPKRKKRVKKEEVKEKVEDEDELEKLQRGTVKRRVRSYDISDSHFDTRPLTLEEQLAELQARARSASYLAAPYKCDVCYKGFKSADTHGLHVVRHSEKYGEFECFICKRRFKNARHLRLHVSSLHTEQFSCKACDFVTRCRGIAIDHQKWHSGNTYECPHCLSKFGKFTSYMSHLRIKHSSRFACELCGYTFVSNRGVEMHKAKRHKLQDAKMKLEGPYCEECKLQFANDEAYLRHLTQSSVHSSDNDPNRIRNDWGCKEQLGVVRRTRKRRAPGVVTHWVENTDRPKQNIPCEQCGEQMDSYRSYAQHFRMAHPGLNRTKFSRVTGACMCEQCGKMFACKALLLDHMMSHSGEKRFKCETCDKAFTNKNNLAVHQRVHGAQVPTYRCPYCERQFHFYQNCNRHVKTVHKGVKQFQCEICGKEFTSAAGQRAHVDHVHHKKPRPKRVRARAPPAPPTAYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00745139;
90% Identity
iTF_00164457;
80% Identity
iTF_00403895;