Basic Information

Insect: Cyaniris semiargus
Gene Symbol: ZEB2
Assembly: GCA_905187585.1
Location: LR994567.1:12886463-12895135[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00095 0.072 14.0 4.2 1 23 241 263 241 263 0.99

2 12 4.2 3.1e+02 2.6 0.0 1 23 270 293 270 293 0.88

3 12 0.19 15 6.8 1.9 1 23 297 319 297 319 0.97

4 12 0.0052 0.39 11.7 0.5 1 23 324 347 324 347 0.97

5 12 0.01 0.76 10.8 0.5 1 23 543 566 543 566 0.96

6 12 2.5 1.9e+02 3.3 1.9 1 22 574 595 574 595 0.90

7 12 0.00099 0.075 14.0 0.0 2 23 606 627 605 627 0.95

8 12 0.11 8.1 7.6 1.0 1 23 630 653 630 653 0.91

9 12 8e-05 0.006 17.4 0.8 2 23 672 693 672 693 0.97

10 12 5.4e-06 0.00041 21.1 0.3 1 23 699 721 699 721 0.98

11 12 1.5e-06 0.00011 22.9 1.4 1 23 727 749 727 749 0.94

12 12 1.5e-05 0.0012 19.7 1.8 3 23 757 778 755 778 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00095	0.072	14.0	4.2	1	23	241	263	241	263	0.99
2	12	4.2	3.1e+02	2.6	0.0	1	23	270	293	270	293	0.88
3	12	0.19	15	6.8	1.9	1	23	297	319	297	319	0.97
4	12	0.0052	0.39	11.7	0.5	1	23	324	347	324	347	0.97
5	12	0.01	0.76	10.8	0.5	1	23	543	566	543	566	0.96
6	12	2.5	1.9e+02	3.3	1.9	1	22	574	595	574	595	0.90
7	12	0.00099	0.075	14.0	0.0	2	23	606	627	605	627	0.95
8	12	0.11	8.1	7.6	1.0	1	23	630	653	630	653	0.91
9	12	8e-05	0.006	17.4	0.8	2	23	672	693	672	693	0.97
10	12	5.4e-06	0.00041	21.1	0.3	1	23	699	721	699	721	0.98
11	12	1.5e-06	0.00011	22.9	1.4	1	23	727	749	727	749	0.94
12	12	1.5e-05	0.0012	19.7	1.8	3	23	757	778	755	778	0.97

Sequence Information

Coding Sequence: ATGTTGGCTTGTCGAATATGTTTGGTTACGGACTTACGATTATACGATATAAACACTACGTACAATCTAAAAACGGCGTACGAAACATTATCTGGATCACAGATATCAAGAGAAGATGGTTTGCCCCAACATATCTGCAGCTACTGCAGCATAATGCTAGTGAAATGCTCATCCTTCCGAGACAAATGTTGTTACACCCAAGAAGTGTTGAAGTATCTTATTGGAAACCATTCTGAGATCACACAAAATCATATTACGTCAATCCAACAGTCCAATCCAATAAAAGGCTTTATAAGGCTGTCTAGAAGCGACACATTACCACTGATTGAGATGGAGTACAAGGAACCAATCGAGAATAAAGCTGTACCTGTACCCATCAAGGAAGAGTACAACCTAGATTTAGATAGCTTAGTCAAGATAGAAGAATGTCTTGTAGAGAAAAAGGTTGAAGAAACAATAGATAAAGTCAAGAAAACCAGGAAGAAAAAGAAAAAGTCAAAGGACTTTAAGATTGAGCCCGACTTGTGTAGTATAGAGATCGATAACCCTGGAAATGCCAATGCTGACTATGAAAGTGACAGGGATCAAGATAATCATATTGAAATGGATGAAGAAAGTGTTGAAGATTTAAAAGAGGCTAAGCTGATAATACTGAGCGTGGAACAGCAGTTCCAAGAGTTGGAGGCTCGGAAGACCTCGGCCAACTACACAAAGTCCAAGTACCAGTGTCATCGGTGCTTCCGCGGGTTCATATCGGAGTCCACGTTCAATAATCACTTGATGAAACATGATCCAAAGAGCGGCGATCACGAGTGCGTTGTGTGCGGCGTGCGGTGGGCGGAGCCGCGTCTGCTGCGCGCGCACGTCATCGCCGCCCACGCCCGCAAGTTCCAGTGCACGCTGTGCGACCACGTGTCGCGCTCCGCCTATCGAGCAAAGGAGCACTACAAATGGCACAATGGTTTCAAATTCAAGTGTAAATTATGTGAAGCCACGTTCGGCAAGTCGACGTCGGCGCTGACGCACATGCGGCTGGCGCACCCGTCGCGCCACTCGTGCGAGGTGCTCTATCTCGCTCCCTCCCCCCTGTGTGTATATGTCTGTCTCACGCGGCGTTCGACGTCGGCGCTAACGCACATGCGGCTGGCGCACCCGTCGCGCCACTCATGCGAGGTGCTCTATCTCGCTCCCTCCCCCCTGTGTGTATATGTCTGTCTCACACGGCGTGTATGTCGCAGCAAGTCGACGTCGGCGCTGACGCACATGCGGCTGGCGCACCCGTCGCGCACTCATGCGAGGTGCTCTATCTCGCTCCCTCCCCCCTGTGTGTATATGTCTGTCTCACGCGGCGTGTATGTCGGCAGCAAGTCGACGTCGGCGCTAACGCACATGCGGCTGGCGCACCCGTCGCGCCACACATGCGAGGTGCTCTATCTCGCTCCCTCCCCCCTGTGTGTATATGTCTGTCTCACACGGCGTGTATGTCGCAGCAAGTCGACGTCGGCGCTGACGCACATGCGGCTGGCGCACCCGTCGCGCCACTCATGCGAGGTGCTCTATCTCGCTCCCTCCCCCCTCAAGTCGACGTCGGCGCTGACGCACATGCGGCTGGCGCACCCGTCGCGCCACTCGTGCGAGGTGTGCGGGGAGTCCTTCGTCGGAGACCTCGGCCTGAGAATGCACAAACGACGCACACATAAGTTCCTAACCGACAACACCTTCCTGTGCGTCCACTGTCAGGCGCGGTTCCAGTGTCAGGAGGCACTGACCAAACATCAGGAGACCACCGCTGACGGAGTCTGTGACACTAACATACCGTGTCTCCAGTGCGGGCAGGGCTTCGCCTCGGAGGAGCTGCTCCAAACACATCTAAAGGAGCATCAATCATTCTCTTGTGATGAGTGTTCGTGCACGTTCACCAGCGAGCTGTCGTACGGCGTGCACGTGGAGCGCGTGCACCTGGGCGTGCGCAAGCGCAGCACGGGCGCCGCGCGACGACCGCTCGACACCGCCGTCTGCGAGGTCTGCGGCAAGGCGTGTGTCAATATGGCGACACTGCGGTACCACCAGCGCACACATACGGGCGAGAAACCGTTCGCTTGCCCCGACTGCCCCAAGCGCTTCTCCGTATACCAAAGACTACAGATCCACATCCGCACGCACACGGGCGAGTCGCCGTACAAGTGTCCCTACTGCCCCAAGGCGTTCAAACACAAAGCCGCGCTCAACAGACACGACCGGGTCCACTCGGGGGCGAGGCCCTACGGCTGCCCGCACTGCGGCAAGACCTTCACGCAGTCCAACTCGCGCAAGATGCACATCAACACCGTACATCTCAAGCTGCCGGCGCCCTACCGCAACCGGAAGTCCACTTAG
Protein Sequence: MLACRICLVTDLRLYDINTTYNLKTAYETLSGSQISREDGLPQHICSYCSIMLVKCSSFRDKCCYTQEVLKYLIGNHSEITQNHITSIQQSNPIKGFIRLSRSDTLPLIEMEYKEPIENKAVPVPIKEEYNLDLDSLVKIEECLVEKKVEETIDKVKKTRKKKKKSKDFKIEPDLCSIEIDNPGNANADYESDRDQDNHIEMDEESVEDLKEAKLIILSVEQQFQELEARKTSANYTKSKYQCHRCFRGFISESTFNNHLMKHDPKSGDHECVVCGVRWAEPRLLRAHVIAAHARKFQCTLCDHVSRSAYRAKEHYKWHNGFKFKCKLCEATFGKSTSALTHMRLAHPSRHSCEVLYLAPSPLCVYVCLTRRSTSALTHMRLAHPSRHSCEVLYLAPSPLCVYVCLTRRVCRSKSTSALTHMRLAHPSRTHARCSISLPPPCVYMSVSRGVYVGSKSTSALTHMRLAHPSRHTCEVLYLAPSPLCVYVCLTRRVCRSKSTSALTHMRLAHPSRHSCEVLYLAPSPLKSTSALTHMRLAHPSRHSCEVCGESFVGDLGLRMHKRRTHKFLTDNTFLCVHCQARFQCQEALTKHQETTADGVCDTNIPCLQCGQGFASEELLQTHLKEHQSFSCDECSCTFTSELSYGVHVERVHLGVRKRSTGAARRPLDTAVCEVCGKACVNMATLRYHQRTHTGEKPFACPDCPKRFSVYQRLQIHIRTHTGESPYKCPYCPKAFKHKAALNRHDRVHSGARPYGCPHCGKTFTQSNSRKMHINTVHLKLPAPYRNRKST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -