Cbre000660.2
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070085.1:6712797-6717934[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00093 0.035 14.3 0.4 2 23 304 326 303 326 0.95 2 12 0.047 1.8 9.0 0.9 3 23 366 387 365 387 0.94 3 12 0.84 32 5.1 2.2 2 23 501 523 501 523 0.91 4 12 0.19 7.4 7.1 0.3 3 20 562 579 561 581 0.94 5 12 1.9 74 3.9 1.9 3 23 596 615 595 615 0.89 6 12 0.053 2 8.8 6.3 1 23 621 643 621 644 0.93 7 12 0.089 3.4 8.1 1.3 1 23 651 675 651 675 0.97 8 12 0.004 0.15 12.4 4.0 1 21 680 699 680 700 0.92 9 12 4.4e-07 1.7e-05 24.8 2.7 2 23 720 741 720 741 0.98 10 12 0.012 0.47 10.8 3.0 1 23 749 771 749 771 0.96 11 12 0.0003 0.011 15.9 0.9 1 23 777 799 777 799 0.98 12 12 0.00037 0.014 15.6 5.0 1 23 804 826 804 826 0.99
Sequence Information
- Coding Sequence
- ATGGCTCGAAACGTGAATATTTTGTtggaaattgacaaaaatggggAATATATGTTCCAAATTCTCTCGAATACGGATCTCGCATGGAAGATGCAGTCAGGAGAAAAGCGTTTCAAGACGATTAGCAGGAATCCCTTGAGTCGCGAGCAAGAAACATGTCAACAATGCTTCGAAACAATAAGTATCAGAATGTTTTGCGAAGATCAAGGAGCGGAATTCGAGtcagttttcattaaaaatgaaactcCGTTGGatattaaagaagaaaaagtcgaAGAACAAAAGCCTGTATCTCAAAAAGTGTCTCAGAAAAATGTTATTGTTTTGAAACCGAGTCCCTTTGAAGGTTTTTCGAAGATtgtttcgattaaaaaaccagaaaaaagatttcttccaattcaaaatgttgttgttaaaCGAATTATCAAACCAAATGAAACAACTTTAAAGGAAATATCcttgaaaaatctgaaaattgttaaaatagtACAAAATACTCAGAAAACTGTTGTTTCTCCCGAAGTTAAAATACCCGACTCGTCAGTAAATGccttaaaatcacaaaaagaaagagtttctgagaaaaattttactgtaGAGAAGGAAAAagatgttcaaattttatctcccataaaagaaattatcgACTTGGAAGCTGAAGAAGAAgtaacaacagaaaaaattattgaaaaaacatcATCTTTGCCCTCAAAAGTCACACGAAAAGTCattgaaaaagcaaaaactcaacaaatttttattcctgATGGTGTTGAATTGCCAGATTTATCGAAATTTGTTCCTCCCTTTAGTTTCTCTGTAAATCAATCAGATGGAAGTACATCATATGTGTCACAAGAACTCCAAAATGGCACTCTTTGGATCACAAATTTCGACTTGAAtgcattaaaatgtgaaatttgtgaCGAAATATTCTCTTCTATTGGCGGATTATGCGTTCATCGACgcgataaacatttttttcaacccaACTCCATCGAATGTGCTGCTTGTCAAGAAATTCGCCAATCAAATCTGGAAAAACTTCGACATACTTTGTATTGTAGAAAACGAGAGGAAATTAAAGCTGGTTATTGTTACATTTGTTCGAAGCAATTTGACGGTCAATTAAAGCTTAGTCGCCATCTGaaagaaaatcacaaaaaagttCTTGAATTTCTTCCAAACGCTGAATTGCTAACGAAATGTTACATGTGCAGAAAAATGATCAGAACGAGATACCAAAACGAGCACTTGAAACATCATCGTAACGAAATGAAGGCAGcccaacaaaaaatcatagaaaaagagaaatatcAAGCGAATTTGTCGGATATCGCAAAATTTCAAGTTGTGCCGGAAGGAGTTGAATTACCATCGACGACTTTATTGCGAGAGACACGATATTCGATGAAGCATCCGCAACCAGATGGAACAATTGCCTATTTAGAAAGTCAGGGCGACAATCTTTGGATAACGAATTTCGACTTGACAAATCGTCAATGCGacttgtgtgaaaaaaaatttccatcaattACGTCTTTGGTATGCCATCGTCgtgattttcactttttccctGCTGATTCAACTGAATGCACTGCCTGCTCCGAACGTTTCTTCGGGGCTTTTACACTAAGTCATTCGCTGTACTGTCGAAAACGGAAAGAAATTCGTGTTGGATTTTGTTACCTTTGTAAGCAACAATTCCAAAATTATGCCTCGCTTGAAAAACATTTGgaggaaaaagtcaaaattcaaaaggaacaaaaagaGATTTATGTCGAttgtgaaatttgtgaaaagaaAGTTTGTAAAAAGCAACTAAAGCAACATATGGCGATTCACGAACGACCGAACATTTTCGAATGTGCTCATTGTGATAGGAAATACACGCGAAAAACGATGATGTTGCAGCATTTGGGACATCATCATTTTCCGTCGTTGTGTAAATATTCGTGCGAGAAATGCGAAaagccaaaatttttcatgaaaagtaACGATTGGCGACGACACATGGACTCGCATGAAGGCAAGAAATTCGTTTGTAATCATTGTGATAAGACATTTACGAAAAATGGATTGATACATCATCGACAACACGTGAAAAATGTCGaattgaaaaaacttaaaggaGACAAAGGGCAAGAGCCTCAAGCAACATGCAACATTTGTGGAAAAGTCTTTAAAAGTGCGTATTGTTTGCGTTCGCACATGAGATCGCATTTACCGAAATCAGAGAGAAAGCACAAATGTCAGTATTGTGAAAAACGATTTAATAGTGTTTCCCAAAAAATCGAACATGAAAGAGATCATACAGgaGAGAAACCTTATGTTTGCACATTCTGTGAAAAAGCTTTTGCGAAGAGACAAACATATACAGATCACGTGAGAGTTCATACAGGACAAGgATATAAATGTGAACATTGTGACAGAATACTAAATGATCACAGTAGTTTTCgtaaacatttgaaaatacACGAAGCAAAGCTGGGTATTAAACTAACGTATTCGAGAGAAGAAAGACGTTTAAAATCGATTGgattgttagaaaaaatgcAAGGAACTACATATTTATAa
- Protein Sequence
- MARNVNILLEIDKNGEYMFQILSNTDLAWKMQSGEKRFKTISRNPLSREQETCQQCFETISIRMFCEDQGAEFESVFIKNETPLDIKEEKVEEQKPVSQKVSQKNVIVLKPSPFEGFSKIVSIKKPEKRFLPIQNVVVKRIIKPNETTLKEISLKNLKIVKIVQNTQKTVVSPEVKIPDSSVNALKSQKERVSEKNFTVEKEKDVQILSPIKEIIDLEAEEEVTTEKIIEKTSSLPSKVTRKVIEKAKTQQIFIPDGVELPDLSKFVPPFSFSVNQSDGSTSYVSQELQNGTLWITNFDLNALKCEICDEIFSSIGGLCVHRRDKHFFQPNSIECAACQEIRQSNLEKLRHTLYCRKREEIKAGYCYICSKQFDGQLKLSRHLKENHKKVLEFLPNAELLTKCYMCRKMIRTRYQNEHLKHHRNEMKAAQQKIIEKEKYQANLSDIAKFQVVPEGVELPSTTLLRETRYSMKHPQPDGTIAYLESQGDNLWITNFDLTNRQCDLCEKKFPSITSLVCHRRDFHFFPADSTECTACSERFFGAFTLSHSLYCRKRKEIRVGFCYLCKQQFQNYASLEKHLEEKVKIQKEQKEIYVDCEICEKKVCKKQLKQHMAIHERPNIFECAHCDRKYTRKTMMLQHLGHHHFPSLCKYSCEKCEKPKFFMKSNDWRRHMDSHEGKKFVCNHCDKTFTKNGLIHHRQHVKNVELKKLKGDKGQEPQATCNICGKVFKSAYCLRSHMRSHLPKSERKHKCQYCEKRFNSVSQKIEHERDHTGEKPYVCTFCEKAFAKRQTYTDHVRVHTGQGYKCEHCDRILNDHSSFRKHLKIHEAKLGIKLTYSREERRLKSIGLLEKMQGTTYL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -