Cbre008880.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:32568535-32572075[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00098 0.037 14.3 2.6 1 21 46 66 46 67 0.96 2 13 5.3 2e+02 2.5 0.4 2 14 169 181 168 187 0.82 3 13 0.44 17 5.9 1.7 2 23 200 222 199 222 0.95 4 13 0.00089 0.034 14.4 3.1 2 23 236 257 236 257 0.96 5 13 0.013 0.5 10.7 3.1 1 23 264 287 264 287 0.94 6 13 0.043 1.7 9.1 0.0 2 23 538 560 537 560 0.93 7 13 0.31 12 6.4 3.4 1 20 620 639 620 641 0.95 8 13 0.42 16 6.0 2.2 1 23 650 674 650 674 0.96 9 13 0.00011 0.0041 17.3 1.5 1 23 679 702 679 702 0.95 10 13 0.00073 0.028 14.7 0.8 1 23 709 731 709 731 0.97 11 13 0.00029 0.011 15.9 2.1 1 23 739 761 739 761 0.96 12 13 0.00044 0.017 15.4 3.6 1 23 767 789 767 789 0.99 13 13 5.7 2.2e+02 2.4 4.9 1 23 794 817 794 817 0.88
Sequence Information
- Coding Sequence
- ATGAAAATCTggaaAGATGAGCACGAAACCTCTGAAACAACGGAAGTTTCAACAACTACAAAGCCTCAACTTGCCACACAAATTACTGTGAGAAAAGCCATTCATCCGTTAGAGAAAAATTCCGTTCATTACATTCACAAATGCGAAAATTGCAACAGAAAATTCCGGTTAAAAAAGCATCTAGCGGATCATTTACGGgcaaaaacttgtcaaaaacaGATGATAATTGGCACGAACATTCACGTCGTTCGTTGTTTGTCTTACTTGCCCGAAGGACTTCGATTACCGGATTTAAACACAATTCGCAGTCCTTATAATCAGCAAATTCGACAAGATGACGGCACAATTACTTACATCAACAAAACTTCGGTAACTTCTTACCTTTGGGTCACGAATTTCGACGTTCACGAGCCAAAATGTGAGATTTGTCAGAAGAAACTTTTGGGAGTCGCACGAAAAATGAATCATCGGGCTTCGATGCATTTCTTTCCGGGCAACAAAAAGACCTGCAATGGCTGTGGAAAGTTAGTCAACAACAAGGaggatcaaaaatttcacacttTGTACTGTTTAGGCAAAGATACAATTCGCACGGATTACTGCTACGAGTGCAAAATGAGGTTTAATGACGACGAAGCGTGTCAAAAACACATCAAACGAGCTCATTACTGGCCAAGGGACGAAGAAAATGACGACGAGAGTGCTTATTGCCACATTTGTGAACGAATGTTTGCCTCAAAATTCATGCTGCGTCGTCATAATTTGCGACACAAAGCTAGTCAGATGCTGTTTTTATGCGAGCATTGCCATTTTGTCACGAGTTCGAAGGAAAAATTGGAATCCCATTTGATTTCAATGCATTTTCCGCAACTAAAACCCATGAAAACGACCGAAACTGACACAAATCCTGATGAAATCCATGAAATTTCGTCAGTTTTCGTGCctgaaatgaattttgaagaCATTATTGCGATCGATTCCGACGGATCTGAGGAAAAAACAGTATCTGAAGGTGAATTTGAAGACTGTGAAGAAACAACTATTGATAATTCATACTCGTTCGAGCCGACAAAGTCACCAAATGAAGCTGATTTGAACGTAAAATGCACCATTGTTCGACTAAATGATGATGGATCGAAGACTAAACATGATGTGCAGCACGTGAAATTGTATAAAAGAGATACTCCCAAAATTTCCGTGAAAGTTGTTCAAGCAGAGGAACTCAAGGCATCTAAAAGGACAAATCAATCTCGAACAGTTTCCGTCAAATATCCAGAAATGCCGATAAAAGTCGTGAATTTGGATCAAATTCCCGttaaaattgccgaaaaaaagctgaaaatggtaaaaaataattttcgcagCTTTTTCGAAGATACAGACGATTTCGAAAATGACCCCTCAGGCACTTCCAGTGATTATTCGAATCAATATTTGACCTCTTTGATGACCTTGAACTACCTTCCGAGTTATGTCACGTTGCCAGTTGTTAAAGATCTCGAACGacctttttatttgttgcaCGAACAAGAAGACGGCTCCTACACttatttacatcaaaaaacGGCTGTTTCGAAAATTTGGATTACGAATTTCGATTTGCAGTGTCTCGAATGCGATATTTGTGCGGAATCGTTTCCGAAAGAGGAACTTTTGGCTTTACATCGAATGGAAGAGCATTTCTTCCCGGCAGACACAATTTTATGCAATGCCTGTGAAAAAACCTTTGAAACGCGTCAGGCGAGGGAATTTCACTCGTTATATTGCGTGGAAAAAGATTCAATTGACATCAGTGGAATACAAGAAGCGAAAATCCTAAAAAgcaataatgaagaaaatgacacaaaaaataggaaattttcCTGTAATCATTGCGATTTTTCAGCTAGTTTGGCGTTTCATTTGCTGCGACACCTTTTATGCATTCATTTCCCTACTTTTGCTAATTTTGAGTGTTCCGAGTGCAATCCAAAGcggtattttttgacaaaagccAAGTACAAGAGACACATGACGACGCACGAAACGAGCAAATTTGAGTGTCATTTTTGTGGCAAGGAATTCAATTCACGAGGAGTTTTGCGTAATCACATTACGTATGTGCATAAGCAGACAGACGAAAAGTATCCATGTGAGATTTGTGGAAAGATTTTCCTGGCGAAGTCAAATCTGCATAATCACAAGTTGTCGCATTTGCCGGAGAATGAGAGGCCATACAAGTGTCAAGTTTGTGGCAAACGTTTTAATCATCCGAAGATACTGAGGGAGCATATGTACGATCATACAGgAGAAAAACCCTACAAATGTCAATATTGCGAGCGAACTTTTTCGCGCCTTCAAACGAGACGCGATCACGAAAGAACTCACACCGGCAAAGGATACATTTGCGAATATTGTGATCGAAGCCCATTTTGGGACCACAGCAGCTTCCGAAAGCATTTAAAATCACATGAGCTCACGATGAACAAAAAACTAACATACACCAAAGAAGAAAGGCGCTTAAAAACGATTGGACTTTTAAATGAATACGAAACGGATGGCGGAAcgacttcataa
- Protein Sequence
- MKIWKDEHETSETTEVSTTTKPQLATQITVRKAIHPLEKNSVHYIHKCENCNRKFRLKKHLADHLRAKTCQKQMIIGTNIHVVRCLSYLPEGLRLPDLNTIRSPYNQQIRQDDGTITYINKTSVTSYLWVTNFDVHEPKCEICQKKLLGVARKMNHRASMHFFPGNKKTCNGCGKLVNNKEDQKFHTLYCLGKDTIRTDYCYECKMRFNDDEACQKHIKRAHYWPRDEENDDESAYCHICERMFASKFMLRRHNLRHKASQMLFLCEHCHFVTSSKEKLESHLISMHFPQLKPMKTTETDTNPDEIHEISSVFVPEMNFEDIIAIDSDGSEEKTVSEGEFEDCEETTIDNSYSFEPTKSPNEADLNVKCTIVRLNDDGSKTKHDVQHVKLYKRDTPKISVKVVQAEELKASKRTNQSRTVSVKYPEMPIKVVNLDQIPVKIAEKKLKMVKNNFRSFFEDTDDFENDPSGTSSDYSNQYLTSLMTLNYLPSYVTLPVVKDLERPFYLLHEQEDGSYTYLHQKTAVSKIWITNFDLQCLECDICAESFPKEELLALHRMEEHFFPADTILCNACEKTFETRQAREFHSLYCVEKDSIDISGIQEAKILKSNNEENDTKNRKFSCNHCDFSASLAFHLLRHLLCIHFPTFANFECSECNPKRYFLTKAKYKRHMTTHETSKFECHFCGKEFNSRGVLRNHITYVHKQTDEKYPCEICGKIFLAKSNLHNHKLSHLPENERPYKCQVCGKRFNHPKILREHMYDHTGEKPYKCQYCERTFSRLQTRRDHERTHTGKGYICEYCDRSPFWDHSSFRKHLKSHELTMNKKLTYTKEERRLKTIGLLNEYETDGGTTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -