Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: -
Assembly: GCA_036172545.2
Location: CM070086.1:12499548-12503130[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.023 0.86 10.0 0.1 2 23 229 250 228 250 0.97

2 12 0.95 36 4.9 0.1 2 23 291 313 290 313 0.88

3 12 0.55 21 5.6 0.0 2 21 329 348 328 349 0.93

4 12 1.6 61 4.2 0.5 2 19 454 471 453 473 0.90

5 12 2.4 93 3.6 7.1 3 23 486 507 485 508 0.95

6 12 0.021 0.79 10.1 1.6 1 23 516 538 516 538 0.97

7 12 0.00095 0.036 14.3 0.5 1 23 544 567 544 567 0.97

8 12 0.22 8.5 6.9 0.0 2 23 607 628 606 628 0.94

9 12 5.6e-06 0.00022 21.3 0.2 1 23 637 659 637 659 0.97

10 12 0.42 16 6.0 5.9 1 23 667 689 667 689 0.94

11 12 1.5e-06 5.6e-05 23.2 1.0 1 23 695 717 695 717 0.98

12 12 0.57 22 5.6 0.3 1 13 722 734 722 735 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.023	0.86	10.0	0.1	2	23	229	250	228	250	0.97
2	12	0.95	36	4.9	0.1	2	23	291	313	290	313	0.88
3	12	0.55	21	5.6	0.0	2	21	329	348	328	349	0.93
4	12	1.6	61	4.2	0.5	2	19	454	471	453	473	0.90
5	12	2.4	93	3.6	7.1	3	23	486	507	485	508	0.95
6	12	0.021	0.79	10.1	1.6	1	23	516	538	516	538	0.97
7	12	0.00095	0.036	14.3	0.5	1	23	544	567	544	567	0.97
8	12	0.22	8.5	6.9	0.0	2	23	607	628	606	628	0.94
9	12	5.6e-06	0.00022	21.3	0.2	1	23	637	659	637	659	0.97
10	12	0.42	16	6.0	5.9	1	23	667	689	667	689	0.94
11	12	1.5e-06	5.6e-05	23.2	1.0	1	23	695	717	695	717	0.98
12	12	0.57	22	5.6	0.3	1	13	722	734	722	735	0.91

Sequence Information

Coding Sequence: ATGACGCAAGAGCTCAACGTGGTCATCAACGTCGCCGAAAATAAGCCCCTGCACACGCAACTTGCGACAAAAGATGAATTACACGAACTGCACATCGAATCGGAGAAACTTGTCTTGGACAAAAACAACTTAAACTTGATTGCTTCGTGTGCCAATTGCTCTCACAACATCCAGTTAAACATTTATTGGCATTCCAGTGACGTCAAAACAAGAGACATGGGCTTCGAGATGCAAATTTGCGCAACAGACCTGAAAGAGGACTTCATAAAAGTCAATCCGGCATGGGATGAGCCATGCGTACTGATAAAAGAAGAACCCGAAACGGAGTCAGAAGACTCGGATAACGATCGAAGTCGgagaaaacgacgaaaaatccGGTCTTCATCGTCAGAGGAGAGTTCGGAAAGTTCAAAATCGGCATCGCCGCCGCCTGTGAAGGTGCGTAAGAAGCGAAAAACGAAGGAATATCGTCCGAAGATGCGAAAGGAAGATTTGCCGGAGATGGTTTTGTATCCGGGAATGACATATTTGTTGCCAGCTGGTCTGGATTTGCCTTCGTTGAAGGATATTAGAGCTCCGTATTTCCATGCGGCGGCCCAAAAAGACGGATCAACCGTTTatatcgagaaaaaaagacagaaaaagtGGCCTGTACGCGTAACGAACTACGATCCTCGTATGACCCGATGTGACATTTGTGATTATGAGGTCCCGAGTTCGGATCGGATGACGGCGCACCGTCGAGGGCACATGTTTTTCAAGTTTAGCGATGTCGAGTGTCGTGCTTGTGGTATATTTTGCGGGTCAAAACCCGAAGACAAGGTGAATCATAGTTTTTTCTGTCCCGGCAAGGATTGTTTGAATGGCTTGCAGTGCATCGAGTGCGACTATGAGGCGCCCGAATACAAATCTTTAAGGGCTCACATGAAAAATAAGCATAAAGGATACAATCCGGCACCCGAAACGAACCGCGATAAGCAAGTTGAGTGTCCGATGTGCAATACCTGGCTAGCTGACGAATATGCCCTCAATACGCACATGAAGTCAAAATGTCGCGCTGCTGACGAGTACAATGCCAGTACAAAGGCGCAAATGGACGAGTATCTTTCGTTGTTGGATTTGCCGAAAGATGCGGTGCTTCCGGATCTTTTTAATCTCAAGGCGCCGCACAGTCGAATGCATCCGCAGCCCGATGGCACGAGTATTTACATCAGCAAGGGAATAAATCACCTGAACGTGATGAATTTCGATCCGAGATGCGAAAAATGCGATTTGTGTGGACGAGGACATTTGAAGAGGAAAGCCGATATGGTTGAACATCGCTTAAAAGATCATTTCTTTCCGGCTCACGCTGATAGTAGATGTCAAGGATGCGGCAGGGAACTCCGAAGTGAAGAAGATAAGACCAATCATTCCCATTTTTGTGGCAAAAAGAAGCAAATTCGCGTGAATTATTGTTTGAAATGCAATTTGCAGTGCAATACGTACTCGAAGTTTGCGAagcatttgaagaaatttcatcaTGGCGAGGGATTGGacaaaaaattcatgtgcCATTTGTGTTCAAGTACCTTCGACTACGAGCGAGAACTGCAACTTCACGTCATTCGTCACATGGATCCGAAACCGTTCAAGTGCGATCACTGCGATGCCGACTTCAAAGGACGTCTTGGGCTCGAAACTCACATGATTCGCGTTCATTTCCCGCAAGAAGCCAAACAAATTTGCAACGCTTGTACGCCCCCGATGCTCTTCGGCAGCGTTAGACCGTACAAAAGTCACTTGAACATGGTGCACTTCAATTCCAAGGAAAAAGTTCCGTGTCCCATTTGCAATATTCCCATCAGAAAAACGGGACTTCAGTGGCATATCACGCGACAACACACGCAACACGAGTTCAAGGACAAGTACGAGTGCACCGTTTGCGGCAAAATTTTCGTCAGCAAGTTCAATTTGGAGGTTCATTCCCTTGTTCACATCCCAGAGGAGCAACGACAACACAGATGTCAGTTTTGCGATAGACGATTCAACTCCAAACAGAATTGCGTCGAGCATGAAAGGGGTCATActggcgAAAAACCATACAAATGTGAGACCTGTGGAAAAGCTTATGCCCGTAAACAAACTCTCAAAGACCATCAACGAGAACACACAGGTCAGGGTTACGATTGTTCCGTGTGCAGTCGAATGTTTACCGATCGCGGGATCTga
Protein Sequence: MTQELNVVINVAENKPLHTQLATKDELHELHIESEKLVLDKNNLNLIASCANCSHNIQLNIYWHSSDVKTRDMGFEMQICATDLKEDFIKVNPAWDEPCVLIKEEPETESEDSDNDRSRRKRRKIRSSSSEESSESSKSASPPPVKVRKKRKTKEYRPKMRKEDLPEMVLYPGMTYLLPAGLDLPSLKDIRAPYFHAAAQKDGSTVYIEKKRQKKWPVRVTNYDPRMTRCDICDYEVPSSDRMTAHRRGHMFFKFSDVECRACGIFCGSKPEDKVNHSFFCPGKDCLNGLQCIECDYEAPEYKSLRAHMKNKHKGYNPAPETNRDKQVECPMCNTWLADEYALNTHMKSKCRAADEYNASTKAQMDEYLSLLDLPKDAVLPDLFNLKAPHSRMHPQPDGTSIYISKGINHLNVMNFDPRCEKCDLCGRGHLKRKADMVEHRLKDHFFPAHADSRCQGCGRELRSEEDKTNHSHFCGKKKQIRVNYCLKCNLQCNTYSKFAKHLKKFHHGEGLDKKFMCHLCSSTFDYERELQLHVIRHMDPKPFKCDHCDADFKGRLGLETHMIRVHFPQEAKQICNACTPPMLFGSVRPYKSHLNMVHFNSKEKVPCPICNIPIRKTGLQWHITRQHTQHEFKDKYECTVCGKIFVSKFNLEVHSLVHIPEEQRQHRCQFCDRRFNSKQNCVEHERGHTGEKPYKCETCGKAYARKQTLKDHQREHTGQGYDCSVCSRMFTDRGI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -