Cbre013147.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- ZEB2
- Assembly
- GCA_036172545.2
- Location
- CM070087.1:30449291-30451330[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 3.4 1.3e+02 3.1 1.0 1 21 203 223 203 224 0.82 2 12 0.0088 0.33 11.3 1.1 2 23 305 326 304 326 0.96 3 12 0.34 13 6.3 0.0 2 19 335 352 334 354 0.91 4 12 1.2 45 4.6 2.5 2 23 366 388 365 388 0.95 5 12 0.89 34 5.0 1.1 2 23 402 422 401 422 0.91 6 12 7e-05 0.0027 17.9 1.7 1 23 430 453 430 453 0.96 7 12 0.00089 0.034 14.4 5.0 1 23 460 483 460 483 0.97 8 12 0.022 0.85 10.0 0.6 2 23 492 514 491 514 0.94 9 12 7.9e-05 0.003 17.7 2.0 1 23 523 545 523 545 0.93 10 12 0.084 3.2 8.2 0.5 5 23 556 574 554 574 0.91 11 12 3.8e-05 0.0014 18.7 0.4 2 23 583 604 582 604 0.97 12 12 1.8e-05 0.00068 19.8 1.7 1 23 610 632 610 632 0.98
Sequence Information
- Coding Sequence
- atgtgttcaaaaacggtcaatttgaTCGTCCGTCACTCGGGAAACAACGATTTTCGCGTTGAAATCGCCGAAAACCCGGAAAATCCGCACACACACAAAGTCGAAAAGGATTCCCGGACAAATGAAAATCTCCAGATAAATTGCACAAAATGCCATGAAAGTATTCAGCTCAAAGTATTTTTCGAAAGCAACAACGTCGACGACGTCGAATCATTTTGGGCGCCCAATTCCCCACCTTTTGTCAAATGCGAGCCCGAAGTCGTGataaaaaaggaagaagatgACTTTGAGATCCCCATGGTCGAAGAGGAGGATGAGGAGCAAGTTTCCGAAGAAGCCGATGACGAAAACGACGAAGATTTTACCATTTCCGACAGCGAAGATGACCTCCCAATTGCGAAATTAACCTCGTCCAGCGTTGTCAAAGAAGGAAAACAAACGCTGTACAAACGAAAATACGGAAATCAAGAAGAAATCATCACGAATTACGATTTATCGAAGAAAGTTTGCGACATTTGTGGGTATAAGAAGCGAACAAATGCCTCGCTTTGGCATTTTATGCGTCACCGCGCGcatcatttcatcgaaaaagagGGAGTTGGCGTCTACAAATGCATCGGATGTCAGAAAAAATTCGACACTCTCGATAAAATTCGGTTTCACACGCGAACCTGTGCTGCTGGCTTGACTCTCGTGACGGAACAGCAAAAGACGGGCACCTTGAAACAACGAAAACCAGCGATTCATTGGAAAGATCGCGTTCCCGAAGGCATTGTTTTGCCGGAAAATGTCGAAAAGTTCCCCGTTCCGTTCTACAAATGCGTCGATCAGCCCGACGGCAGCAAAATTTGGATCGAAAAGTCGCAGTCGACGAAGGGATTGCGAATTAGTAACTTCGATACGCGACTTTTGACATGCGATTTGTGCGAAACTACCGTCAAATATCGCTCCATGTACATCCGACATCGCAAGTTACATCTCTTTCAGCAAGAAAATGACGACAAATGTCTCGGTTGCGACCAAATATTTCCCACTGCAGACGATCGCGTTGCTCATACTTACTTCTGCCCGAAATGGAAAAGTGTGGATATCACCAAATGCAGTGCTTGCGGCTTCGTCTGCGGCGGTTATCAACAGTTACGAAGTCATATTCACAGCAATCACGGCAAAAATAAGGAAGCGTACAAcacaaaatccaaaataatgtGTCACATTTGCTCCCAGGAGGTGCGTCGCAGTAAAATGTATGCCCATCTCTTGCGTCACGAGCATCCGGAGGGACGTCCTTACGCTTGCGCTCACTGCGATCGTCGTTTTTCCGGTCgaaataacctcaaaatcCATCTCATCAAGTTCCATTTCAAGTCAATGGCGGAATATCAGTGTCACGTGTGCCCCCTTTGCTTCAAGGGGCGCCAAGAATACGAGAAACACATGTATTCGCGTCACAAAATcggcaaaaatcaaaatgtcacGTGCAAGCTATGCCAAAAAGTACTCGCGAACGACAGTTCCTTGCATGCGCATAACCGCGCGATGCATACGGACGCTTCGGAGAAGCAAAAATTCGAATGCCCGCATTgcgaaaagtttttcttcaagaaaCGCAACTTGGAGGCACACATTCCAACGCATCTCCCGGAGAGCGAAAGGCCGTTCAAGTGTTGGTGCGGCCGTGGATATGCCACGAGAGACAAATTGACGAAACATAATCTCGAACATACGGATCCGACGAAACTTTTGTCCGTTTGCAGCGTTTGCGGGAAGGCTATGAAGAGTAAACAGTCGTTAAAAGTCCATATGCGGATCCATACGGGCGAACAGCCGTACGAATGTAACTTTTGTTCGCGAAAATTCGCAGATCGCGGCAATTATCGGGTCCATATGAAGCAGCACGAGAAGGAGCTGGGACTCAAATTGACTTTTACGCCCGAAGAACGACGTTTAATGAAGCTTCACGTCTTAAAACCAGACCAAATGCTCGAAAATCCAGGTAGATCGGGCACCGAGGAAGTCAATCAAATCGCAAAATATCTCTAA
- Protein Sequence
- MCSKTVNLIVRHSGNNDFRVEIAENPENPHTHKVEKDSRTNENLQINCTKCHESIQLKVFFESNNVDDVESFWAPNSPPFVKCEPEVVIKKEEDDFEIPMVEEEDEEQVSEEADDENDEDFTISDSEDDLPIAKLTSSSVVKEGKQTLYKRKYGNQEEIITNYDLSKKVCDICGYKKRTNASLWHFMRHRAHHFIEKEGVGVYKCIGCQKKFDTLDKIRFHTRTCAAGLTLVTEQQKTGTLKQRKPAIHWKDRVPEGIVLPENVEKFPVPFYKCVDQPDGSKIWIEKSQSTKGLRISNFDTRLLTCDLCETTVKYRSMYIRHRKLHLFQQENDDKCLGCDQIFPTADDRVAHTYFCPKWKSVDITKCSACGFVCGGYQQLRSHIHSNHGKNKEAYNTKSKIMCHICSQEVRRSKMYAHLLRHEHPEGRPYACAHCDRRFSGRNNLKIHLIKFHFKSMAEYQCHVCPLCFKGRQEYEKHMYSRHKIGKNQNVTCKLCQKVLANDSSLHAHNRAMHTDASEKQKFECPHCEKFFFKKRNLEAHIPTHLPESERPFKCWCGRGYATRDKLTKHNLEHTDPTKLLSVCSVCGKAMKSKQSLKVHMRIHTGEQPYECNFCSRKFADRGNYRVHMKQHEKELGLKLTFTPEERRLMKLHVLKPDQMLENPGRSGTEEVNQIAKYL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -