Cbre002671.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070085.1:25552737-25554242[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 1.5 57 4.3 0.4 3 17 55 69 54 69 0.93 2 11 0.00055 0.021 15.1 3.3 2 23 185 207 184 207 0.96 3 11 7.4e-05 0.0028 17.8 0.7 2 23 220 242 219 242 0.94 4 11 8.3 3.2e+02 1.9 0.1 3 9 254 260 253 262 0.87 5 11 0.00051 0.02 15.2 1.6 2 23 279 301 278 301 0.91 6 11 0.00016 0.0062 16.7 0.1 2 23 310 332 309 332 0.96 7 11 0.012 0.45 10.9 3.6 1 23 339 361 339 361 0.98 8 11 3.2e-05 0.0012 19.0 1.0 1 23 367 389 367 389 0.97 9 11 1.6e-05 0.00062 19.9 2.8 1 20 395 414 395 417 0.93 10 11 0.061 2.3 8.6 0.3 1 23 422 446 422 446 0.93 11 11 0.15 5.6 7.4 1.4 5 21 454 470 451 474 0.89
Sequence Information
- Coding Sequence
- ATGAAAAAGATTCCTTGTCGCGTTTGCCTGACGACCGGCAGTCCGCGCATCGATATGTTGTCGAATCCGCTCCCCAAATACCCGGGAGCCGACGTTTCGTTGCTGGAGATGTTCGCACTCGTCACCGAAATCGCAATGCAAGTCGGAGAAAACAGTATTTTATGCAGCAATTGCCAGAAACGGCTCACCGATGCCTACAACTTTCGTTGCGAGGCCCAGCGCTCGAATGTTTTGCTGGAAACCATCATTTTGCCACAAAAAGAGGAATATTCCGTTGCAGTAAAGGAAGAAGGCGCGGACTACGAGGACTACGAAGCACTTGAGAATGTCGAGACCCACATCAAAGACGAAAGTTTTGCAGCACCACCGGCACCGCCGCCACTCACAAAGAAGGAAACTCCCGTTGTGGTAAGGCGCCGACGAAATCGAGCATCATCGATCCCCTTGCCGCCCGCCACTTTGACACGATTCCATTGTCGCTACTGCTTCGGACACTTCCCGAACAGCTTGAAAAAGCACGAAGCTGAACACATTGTCGCAAACGGCGGCTTGGAATGTCACCATTGTGGCAAGAAATTCCGCATCCGGAATCTCATACGAGAACATTTGCGAATGGTTCATTTCACGGACAAATCGGATCCGAATCGCGTACGCTGGACATGCGACTTGTGCGGACGCTCGTATTCGGAAAAGGCGTCGTTGCGCAATCACAAACGCGACAAACACTCGGACAACccaaaaattcaccaaaaagTACTGTGCCCGCTCTGTGGCAAGGCAGTGCGTTGCGTTTCCGTGCACATTTATCACATGCACGAACAACACGATCTCCTTACGTGCGACTTGTGTCAGAAGCAGTTCAAGACAAAAATGACCCTCAAAGCACATTTCCAGGCGCGTCACATGGAAAAGAAACCGCCGGAGATCCCGTGCCCCGAATGCTCGAAAATGTTCGGTACCGAGTCGCAGGTCAAGGATCACTTGCAACGCGTTCATTACACCGTCGGACAAAAATTCCAATGCGAAATCTGCTCCACCAAATTCAAGTCGATGCAAAGTTACAAGTTCCACATGAAAATGCATCAGGCGAGTTTGGATCACAGATGCGAGGTGTGCGGAAATGGGTTTAAAACGCGCGCCTATTTATTGCAACACATGAAAGCGCATTcggaagagaaaaattacacATGCGACGTCTGTCACAAGAGTTTCAAGCGTTCCGGCCAACTTGTCAAGCACAAATGGACACACGAGGACCGCAGATTCTACTGCGAATATTGCCCGAACGAGAGTTTCATCGATGCCACCACGCTCCGGATGCACAACGAGAAAGTCCATCTTGGTATTCGGTACAAATGCGAGTGCGGCAAGGAATACGGCATGAAGAAACACTTGCGACAACACCAAACGGCACAGAATCACGACAAAAACAAGTGGTCGAAAGTAATTCCGATTGGCGTCGAACTTGAAAGTAACTCTGGCTATTGGTCATCATCAAATCAGTAA
- Protein Sequence
- MKKIPCRVCLTTGSPRIDMLSNPLPKYPGADVSLLEMFALVTEIAMQVGENSILCSNCQKRLTDAYNFRCEAQRSNVLLETIILPQKEEYSVAVKEEGADYEDYEALENVETHIKDESFAAPPAPPPLTKKETPVVVRRRRNRASSIPLPPATLTRFHCRYCFGHFPNSLKKHEAEHIVANGGLECHHCGKKFRIRNLIREHLRMVHFTDKSDPNRVRWTCDLCGRSYSEKASLRNHKRDKHSDNPKIHQKVLCPLCGKAVRCVSVHIYHMHEQHDLLTCDLCQKQFKTKMTLKAHFQARHMEKKPPEIPCPECSKMFGTESQVKDHLQRVHYTVGQKFQCEICSTKFKSMQSYKFHMKMHQASLDHRCEVCGNGFKTRAYLLQHMKAHSEEKNYTCDVCHKSFKRSGQLVKHKWTHEDRRFYCEYCPNESFIDATTLRMHNEKVHLGIRYKCECGKEYGMKKHLRQHQTAQNHDKNKWSKVIPIGVELESNSGYWSSSNQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -