Cbre005614.2
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:6338814-6340282[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00033 0.013 15.7 1.8 1 23 113 136 113 136 0.93 2 11 3.2 1.2e+02 3.2 0.2 3 23 155 177 153 177 0.90 3 11 2.3 88 3.7 0.5 6 23 186 203 186 203 0.94 4 11 0.0028 0.11 12.8 0.7 1 23 209 231 209 231 0.97 5 11 0.00049 0.019 15.2 5.4 1 23 239 262 239 262 0.97 6 11 0.00011 0.0042 17.3 2.3 3 23 274 295 272 295 0.96 7 11 0.0081 0.31 11.4 0.5 3 23 303 324 302 324 0.95 8 11 2.9 1.1e+02 3.4 2.8 1 23 330 349 330 349 0.79 9 11 0.00012 0.0045 17.2 1.5 2 23 357 378 356 378 0.97 10 11 2.3e-05 0.00089 19.4 1.8 1 23 384 406 384 406 0.98 11 11 0.0003 0.011 15.9 4.8 1 23 412 435 412 435 0.95
Sequence Information
- Coding Sequence
- ATGGATTTAAGCTTACCTTATTGTCGATTTTGCTTGTCAAACCTTGAAAAAGTCACAGAATTCGTGGATATCCAACAATATTCGGACCTCGTTGATAAAATCATTCAGATTTTTCACTTCAATCCTGTggaaatagataaaaatccatcaattttGTGTCTTGAATGCCATTCTCGAGTACTATCCACCGCCGCGTTCAtcgaaaatgtacaaaaaaatcaaaaagtaataGAGGAAAGTCTCGAACGGAGTGAAAATGTGTTCGTCAAACAAGATCCTGAGCTCCAAATGGATGTTGAATACTTAGAAGAAGCATTTGAAACGAGTTCCGAGTCTTTCATCTGCCACTTgtgtgaagaaaatttctcttcgaagcaatttttgaaGCAACACATGGACGAAGAACACTTGGAAACTtccaaaaaacatcaaaaagttCCTGAAATCGACAAATATCTCATTTGTGAGCTTTGTGACGCGCAAAATTTCCCAACTTTTAGTCAAATGTCGGATCATTATCAAGCCAAACACGGGATTCGAGGGTACGTTCGTTGCTGTAACAAGCAATTCTTCACAAAGAAGTCTGTAGTCAATCATAACGAAGTTCATTTGAATCCTGTCGACTTTATGtgcaaaatttgtcagaaattaTTGCCGGATAAATACACTTTAAGAGATCATGAATTGAGACACAATCCTGACGAAgcgaaaaaattcgaatgcGATCATtgccacaaaaaatttcatgtccaAAAGGATTTAGCTGATCACATAAATCGTCTCCATCGCACGAAAACGGAGCCAGAGAAACgtcaaaattgtaaattgtGCGAAAAATCGTTCGTTTCGAAATATTCTCTCATGACACACAATCGAAGGTTTCACATGGACCTCGAAAAACCAATttgtgAAACATGCGGCAAAGAATGTCTTTCGAAAGCCGACTTAACAGCTCATATCAAAGCTCGTCACACGAAAAGTGTTCGTCATAAATGCGATATTTGCGgaattttcgtcaaatatctgCAAAAACACAAGCAAATTCATGTCGAGTCAAAGTTGCATCTGAAATGCGATATTTGCGGGTTGGAAACGACGACGCACAAGTATCTGCGATTGCATATGAAGATCCATTCCGGTGAAAAACCGTATACTTGTTCAACGTGTAATGCTTCGTTCAAGCGGAAAAACACCTTTGAAGATCACATGAGCATCCATAACGGCATTCCGAGGcatttttgcaacttttgcGGACGATCGTTCAATAATTCGGGCAACAAATCCAGACACATAAAACGCAGGCATTCACAACAAATGgcagaaatgaagaaaaaaatgaaaggaatTAAGGAAAAAGGTCCAAGTTTTGGTCCAAGAAgagaagttttgaaaaaaataaattaa
- Protein Sequence
- MDLSLPYCRFCLSNLEKVTEFVDIQQYSDLVDKIIQIFHFNPVEIDKNPSILCLECHSRVLSTAAFIENVQKNQKVIEESLERSENVFVKQDPELQMDVEYLEEAFETSSESFICHLCEENFSSKQFLKQHMDEEHLETSKKHQKVPEIDKYLICELCDAQNFPTFSQMSDHYQAKHGIRGYVRCCNKQFFTKKSVVNHNEVHLNPVDFMCKICQKLLPDKYTLRDHELRHNPDEAKKFECDHCHKKFHVQKDLADHINRLHRTKTEPEKRQNCKLCEKSFVSKYSLMTHNRRFHMDLEKPICETCGKECLSKADLTAHIKARHTKSVRHKCDICGIFVKYLQKHKQIHVESKLHLKCDICGLETTTHKYLRLHMKIHSGEKPYTCSTCNASFKRKNTFEDHMSIHNGIPRHFCNFCGRSFNNSGNKSRHIKRRHSQQMAEMKKKMKGIKEKGPSFGPRREVLKKIN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -