Cbre006066.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:10956948-10959735[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 3.5 1.3e+02 3.1 0.4 1 16 35 50 35 52 0.83 2 12 5.6e-06 0.00021 21.3 1.1 1 23 77 99 77 99 0.96 3 12 7.6e-05 0.0029 17.8 0.8 1 23 219 242 219 242 0.97 4 12 0.0014 0.053 13.8 1.3 3 23 252 273 250 273 0.95 5 12 0.13 5 7.6 0.8 1 23 303 326 303 326 0.92 6 12 0.00027 0.01 16.0 1.7 2 23 345 366 345 366 0.96 7 12 0.0057 0.22 11.9 1.8 3 23 375 395 373 395 0.97 8 12 0.0063 0.24 11.7 0.9 1 23 400 425 400 425 0.95 9 12 0.0016 0.059 13.6 0.5 1 23 431 454 431 454 0.93 10 12 1.4 54 4.3 1.5 3 15 481 493 480 503 0.84 11 12 4.3e-05 0.0016 18.6 1.3 2 23 511 532 510 532 0.96 12 12 0.0039 0.15 12.4 0.6 1 23 537 562 537 562 0.96
Sequence Information
- Coding Sequence
- atgacgagtTTCCTTCCAGATCTGAAGGAATTTCCGAATTTcttgtcaaataaaattgcattttcggAAGAAACCAACAAAATTAGTACTCCAGAAACTTTCTACCGATGCGGCATTTGTCAATCtcgtttttttcacttaacaTCCTTCATCGTTTGTTGTGGCAATCACTTACCATTCTCAATAAATTTGAccgataacaacaaaaataccaCAGAAAATCGAGTTTTCACATGCAAAATCTGCGGAAAAACTTTTGTGAGACGACAAACGTATCGAGATCATTTAATTGGACACAAAAATCCCTTGATAAAATGCTGTACAATTTGTTCGACGCAATTCAGTAGCGGAATTATCGCAAGCAAGCACAAGAAAAAGTTTCATCCGGAGCTGTATGAACAGGAATTGCAGAAAAAAGCAACAGAAAGAGCAAAacgaggaaaattaaaaactcatcaCATCAAAAATGAACAAGAAAAACCCCAAATTAAGCATTTTCGAATTATTCTCAGTCGAATGGCTTTGGAtggatttgtgaaaaatgattGGATTTATTTGCCAAAAGAGTCAGTTGAGGATATGAAGAAGAATTACGAAATAAAAtctgaagaaatttcaaatgacaacaaaaatttaaAAGAGAGTAAAAGTACTTTTGACTGTAAAATCTGTGGTAAAACTTTCAAAGAAgcccaaacaaaaaatttacatattcgACGTGTtcacaaacaaattttcgagggtcaaattttttgtcattattgtGGAAAAGATTTTATGGGCAAAGGATATTTATTAAGTCACTTTCGAAATGTGCATTTTGACGAAAACGGTGTCTTCCGAGAAACTTCAAATTCGagaaaatctaagaaaattgATAACAATCGAAATAAGGATAAGCAGTcgtttgtgtgtgaaatttgTGGGGAAGTCAAGGAAACAAAAGGGACCATGATGAAACATAGACACGAAAAACACGGAGTTTTGGATcctgaatataaaattattttacaaaaagACTACGAAGAAAATGTTTGTCCTCATTGTGGCAAACCCTTCACCTCTATCCGAAAATTTAAGGATCACGAAAAATACCACTTGAGAGAACagccaaatttattttgcacaGTTTGTGGCATCAAATGCAAAACTGACATCTTTTTGCGAGCTCATATGCAACGACACAACGAAAAAACGTTTTTCTGCAAGTTCGAAGGTTGTCGCAAAGGATTCGCCGTAAAGTATGACTATCTGACTCACATAAAAAGAGCTCATGGCTCCGGCGAAAGTTTTCCGTGCAAAAGATGCGATCAAGTATTTCGAACATGGAAGTTGAGACGATCGCATGAAGAAGTCGAACACGGCATTGTCAAAGTCAAGTTGCAACGAAATAAACGAATTACGCCGAATGCCAGTTACAAggaaGATGAAGGCGGAAACTGTCGCTTTTGTGGCAaacatttcgataaaaatagtTACAGAAAGCTTCAAAACCACGAatatcatcacaaaaaaataattccgaaCCTCCATTGTGAAATTTGTGGAGCCAAAAGTACTACGGAATACAATCTGAAACGCCATATGGAGCGTCATGGCGACATTAAGTATTATTGTCAGTACCCGGGATGCGGAAAAGGCTATAAAGTGAAACACGATATAAGGATTCATGCTAGACGAGCACATAAAGATGTAAAAGAGCCTTTCAGTTGA
- Protein Sequence
- MTSFLPDLKEFPNFLSNKIAFSEETNKISTPETFYRCGICQSRFFHLTSFIVCCGNHLPFSINLTDNNKNTTENRVFTCKICGKTFVRRQTYRDHLIGHKNPLIKCCTICSTQFSSGIIASKHKKKFHPELYEQELQKKATERAKRGKLKTHHIKNEQEKPQIKHFRIILSRMALDGFVKNDWIYLPKESVEDMKKNYEIKSEEISNDNKNLKESKSTFDCKICGKTFKEAQTKNLHIRRVHKQIFEGQIFCHYCGKDFMGKGYLLSHFRNVHFDENGVFRETSNSRKSKKIDNNRNKDKQSFVCEICGEVKETKGTMMKHRHEKHGVLDPEYKIILQKDYEENVCPHCGKPFTSIRKFKDHEKYHLREQPNLFCTVCGIKCKTDIFLRAHMQRHNEKTFFCKFEGCRKGFAVKYDYLTHIKRAHGSGESFPCKRCDQVFRTWKLRRSHEEVEHGIVKVKLQRNKRITPNASYKEDEGGNCRFCGKHFDKNSYRKLQNHEYHHKKIIPNLHCEICGAKSTTEYNLKRHMERHGDIKYYCQYPGCGKGYKVKHDIRIHARRAHKDVKEPFS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -