Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: L
Assembly: GCA_036172545.2
Location: CM070085.1:5732528-5746033[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.3e-05 0.0013 18.9 1.7 1 23 133 155 133 155 0.97

2 18 0.19 7.1 7.1 6.8 1 23 161 183 161 183 0.98

3 18 3.9e-06 0.00015 21.8 3.9 1 23 189 211 189 211 0.99

4 18 2.8e-05 0.0011 19.1 0.2 1 23 217 239 217 239 0.98

5 18 0.031 1.2 9.6 1.8 2 23 348 370 347 370 0.97

6 18 0.06 2.3 8.7 0.3 1 23 467 489 467 489 0.95

7 18 0.00076 0.029 14.6 0.1 1 23 497 519 497 519 0.97

8 18 0.00082 0.031 14.5 1.6 1 23 527 551 527 551 0.91

9 18 0.043 1.7 9.1 0.1 1 23 556 579 556 579 0.93

10 18 0.084 3.2 8.2 4.1 1 23 586 609 586 609 0.98

11 18 0.0013 0.051 13.9 1.9 1 23 641 663 641 664 0.96

12 18 5.8 2.2e+02 2.4 0.7 1 23 805 829 805 829 0.85

13 18 0.00051 0.02 15.2 0.2 2 23 838 860 837 860 0.96

14 18 0.0046 0.17 12.2 0.1 1 23 866 888 866 888 0.98

15 18 8.9 3.4e+02 1.8 0.3 2 23 896 917 896 917 0.92

16 18 0.0074 0.28 11.5 0.2 1 23 1013 1035 1013 1035 0.95

17 18 0.013 0.48 10.8 0.0 1 23 1045 1068 1045 1068 0.93

18 18 5.3 2e+02 2.5 0.8 1 23 1075 1097 1075 1097 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.3e-05	0.0013	18.9	1.7	1	23	133	155	133	155	0.97
2	18	0.19	7.1	7.1	6.8	1	23	161	183	161	183	0.98
3	18	3.9e-06	0.00015	21.8	3.9	1	23	189	211	189	211	0.99
4	18	2.8e-05	0.0011	19.1	0.2	1	23	217	239	217	239	0.98
5	18	0.031	1.2	9.6	1.8	2	23	348	370	347	370	0.97
6	18	0.06	2.3	8.7	0.3	1	23	467	489	467	489	0.95
7	18	0.00076	0.029	14.6	0.1	1	23	497	519	497	519	0.97
8	18	0.00082	0.031	14.5	1.6	1	23	527	551	527	551	0.91
9	18	0.043	1.7	9.1	0.1	1	23	556	579	556	579	0.93
10	18	0.084	3.2	8.2	4.1	1	23	586	609	586	609	0.98
11	18	0.0013	0.051	13.9	1.9	1	23	641	663	641	664	0.96
12	18	5.8	2.2e+02	2.4	0.7	1	23	805	829	805	829	0.85
13	18	0.00051	0.02	15.2	0.2	2	23	838	860	837	860	0.96
14	18	0.0046	0.17	12.2	0.1	1	23	866	888	866	888	0.98
15	18	8.9	3.4e+02	1.8	0.3	2	23	896	917	896	917	0.92
16	18	0.0074	0.28	11.5	0.2	1	23	1013	1035	1013	1035	0.95
17	18	0.013	0.48	10.8	0.0	1	23	1045	1068	1045	1068	0.93
18	18	5.3	2e+02	2.5	0.8	1	23	1075	1097	1075	1097	0.94

Sequence Information

Coding Sequence: atggcaatgaaaatgttttatagaGGTCCAAGCTCACGCTTAGAGActttaattgagaaaattcaaaagaataataatacgGATTCGCCGCCagaatctTATTCGACGCACACCTCCTGCAGTTTTTCGCCTTCGATCGCGGATAGCGACAATGGAGGCATCGCAACGCCCAATTCGAGTGTCAATGATGCTTCAAAAACTCCAGCAGCAGCAGGTGACGACGCGAAAAATCCAACAGAGACAAAATCTGACAACAACACGGAACAACATGGCAAGCATAAAAACAACGAAAGTCGTCATCAGTACaatcaccatcatcatcatcatcatcacaagaACGGTTGCACGAAAACCGGCAAATGCAGTAGCAACGCAGCAGCAAACCACACGGGAACGTATaattgtcaattttgtgaTAAGACATTTCCGCGTCTCGGATACTTGAAGAAGCACGAACAGagcCATGCTGATCATATGCCCTTCCAATGCGAATATTGCAAGCGACTTTTCAAGCATAAAAGATCTCGAGATCGTCATACGAAGCTTCACACGGGCGATCGACGATACAAATGTCTTCATTGTGAAGCTGCTTTTAGTCGaagtgatcatttaaaaattcacatgaaAACGCATGACAATCAGAAACCCTTTCAATGTACCGTTTGTAATCGTGGTTACAACACCGCCGCCGCACTTACGTCTCACATGCAAAACCACAAGAAGCAAATCGCCCTAACGGGCAGTCCAACATTGACTTATAGCTCACGTTACAGTCCCCGTTCGACGGGATCTGCTTCAAGTATCACGAGTGTTACGCCCAAACGTCGTCCCGAATCAGTTGGAGCGACGCCAATTAAATCTCCGCTCGATTTCATGAACTTCCCCAAGTCTTCGAACGGGTTTTCGTGTCTCTACTGCACCAAATCTGACTTTTTGAGTCTCGACCAACTACATTCGCACATCCAATCGATGCACGGAGGTCCCATGAAGACAAATTTATCGTCGCCCGCGAGCATCGGAAGTCCCATTCCGTTCCAAATTCAATGCGAATTTTGCACGATCAAGTGTGCCAACATGCAAGCGTTGTTCAATCACATGCGAAGTACCCATCTGGACAAAATTCAAAGCCCAAATGCGTATTTGGAGCAATTTAAGACAATGTATCCGTACAGTCCTCGTTTACGGGTGCAAAATGGGCAAGATGACACCCCATCAACGCCCGTTATTAAAGAAGAAGCCAAAAATTCACCCGAAAACATCAAGATCGAGGAACAAGATGACGACGAAGAACAAACATCTCCCACAGATTTGAGTCAACCAAAGGCGAAAAAGCCCAAATTAGACGTCAGCAACGAAAAAGATCAATCTCCGAATTCGAATGAAATGCGTCCCGGGACATTTTTGTGCAACCAATGTAACGCAGCATTGCCTAATTTTGAGTCGTTTCGAGCACATTTGAAGTCCCATTTGGACAATGGAGGCTCGTCATTCGTGTGTCAAACATGCGGAAGTTCGTTTGCCGATCAAATCGAGTACGAGAGACACGtaatttcgcattttttggTTCAGGCATCGGAATTTTGTTGTACTCCGCAATGCAATAAGACGTACAATAAGCCTGACGACTTGCAGAAACACTTGATTGACATGCATGCACAAACTTTGTACAAATGTAGTTTGTGTTCGGAGATATTTGAGACGAAAGTAGCTATTCAAGTACATTTTGCAGTGGCTCATTCCAACGAAACGAAGATTTTTAGATGTTCTGCGTGTTCGGATAGCTTTAAAAATGACAGAGATTTTAGaCATCATATCCGTACAAGACACATCAATCCAGGAGCTGTTCAATGCGTGTTTTGTCGTGTTGTTTGCGCTTCGGAGCTCGAAATGCATTTTCATCTTGCTGCTCATGCAAAACAATACAaatgcCCTGCTTGTCCCGAATCATTTCACGTTGAATTTTTGCTCGATCGTCACATGCAAACGCATCATGCTGCTGATCAAAAGTCTCCCATTAACAACAATACCATCGACTATCATTCCCAATACCCGTTAAAATCTCCTTTTTACAACTTTGGTGCATCGAAATTCTATAATCCGTTGCAAGTTGACACTTTGGGCATCAAACATCCGAGTCATTTGTTCCAAGGATTGTACGATTCGATGGCAAAATCGCAACGTTTCATGGATCAACAGCAGAAATCGTACTTGAGTCCCAATAAAGCGTCAATTCCGGGCTTTAATCCTGCTCGTCCCGGAACAAACACAACATATTCGCCCGAAAATGGAACCCGCCCGGAACTTTATTCGCCAAAAAATGCAGGAATTTATTCTCCGCTCAACAGATTTATCGCTACAACGCccgaaatcaacaaaaattcgaTGCCTCCGGCGAGAAACGAAGCGAAAATGTACAGTTGCGGGATTTGCGAAAGAAGCGATTTCAGTACAGAAGCTGAGGTTCACACACATCGCAAGATTTCGCACAATTTGAAGACCGGAGTGAGTCTCAGATGTGCTTATTGTAACGGAGATTTTCGTtcaagaactgaGCTCGAAAACCATATGAAAGTCGCTCACAACACTTCCGGCAAACACAAATGTCTCATTTGTGACGAAATTTTCCCGTCGCCCGCGGTTTTAGCTGAACATAAACTCACCCATTGCAAAGTTGGCAATTCGGGACGTTGTTCGCACTGTTCTGCGGCAATTGATGACATCACAGCGTTCAAAACGCACTTGGCAGAGCACAGCGGACAAGAAATCCCGATTCAATGTATTTGTTGTCGACAAACTTTGCATTCGGAATTCGAGATTAGTTTACATGCGAGatttcatacaaaaacagCAGAAACGAGCGAACACACATGCGCTTTGTGTCTCGATCCGATTCCCTCGACATCCGACAAGAAAATTTGCGAAACTTGTTtgaaaaaacacaatttttccgCAACGAAAATTCTTCCGCCTCATCCTTTCAGACCGTTGCGACGTTCATCGCACGACACCGCATCAACTCCCGCCAATCCCGCGGATTTCGAGTgtaatttgtgcaaaaaatctCTCGTTTCGGAGGCAAAACTACGCGAACATTTGGTCGAACACACTTTCGCCGGTTGCGAAGATCGCGGATTCATTTGTTACATTTGCTCCTCCGTCTTTACCGGTCCCAGCGGATTGTTGTCGCACATGGAAGACATTCACGGCAGCAACGCCAAACCTTACGATTGTTCTCGATGCGCCGCAAAATTCTTTTTCCGCGCTGAACTCGATCATCATGCCGTGATGCACGAACCGCTCgcgaaagaaattgaaaaaccgTCGATTCACGAACCGGAAATCAGCGTGCGAGAGGGATCCGTGTCTCcaaacatcaaaaaagaagTTAATGGCGAGTCGGaggacgaagaagaagaggaatATATTGAAGTCGAAGAACCAAGAACAGAAACTTACAAGCAGGAAAATGGCGAAAGTCCTTCGAAAGaggaagaagagaaaaataatgaagaaaaataa
Protein Sequence: MAMKMFYRGPSSRLETLIEKIQKNNNTDSPPESYSTHTSCSFSPSIADSDNGGIATPNSSVNDASKTPAAAGDDAKNPTETKSDNNTEQHGKHKNNESRHQYNHHHHHHHHKNGCTKTGKCSSNAAANHTGTYNCQFCDKTFPRLGYLKKHEQSHADHMPFQCEYCKRLFKHKRSRDRHTKLHTGDRRYKCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQIALTGSPTLTYSSRYSPRSTGSASSITSVTPKRRPESVGATPIKSPLDFMNFPKSSNGFSCLYCTKSDFLSLDQLHSHIQSMHGGPMKTNLSSPASIGSPIPFQIQCEFCTIKCANMQALFNHMRSTHLDKIQSPNAYLEQFKTMYPYSPRLRVQNGQDDTPSTPVIKEEAKNSPENIKIEEQDDDEEQTSPTDLSQPKAKKPKLDVSNEKDQSPNSNEMRPGTFLCNQCNAALPNFESFRAHLKSHLDNGGSSFVCQTCGSSFADQIEYERHVISHFLVQASEFCCTPQCNKTYNKPDDLQKHLIDMHAQTLYKCSLCSEIFETKVAIQVHFAVAHSNETKIFRCSACSDSFKNDRDFRHHIRTRHINPGAVQCVFCRVVCASELEMHFHLAAHAKQYKCPACPESFHVEFLLDRHMQTHHAADQKSPINNNTIDYHSQYPLKSPFYNFGASKFYNPLQVDTLGIKHPSHLFQGLYDSMAKSQRFMDQQQKSYLSPNKASIPGFNPARPGTNTTYSPENGTRPELYSPKNAGIYSPLNRFIATTPEINKNSMPPARNEAKMYSCGICERSDFSTEAEVHTHRKISHNLKTGVSLRCAYCNGDFRSRTELENHMKVAHNTSGKHKCLICDEIFPSPAVLAEHKLTHCKVGNSGRCSHCSAAIDDITAFKTHLAEHSGQEIPIQCICCRQTLHSEFEISLHARFHTKTAETSEHTCALCLDPIPSTSDKKICETCLKKHNFSATKILPPHPFRPLRRSSHDTASTPANPADFECNLCKKSLVSEAKLREHLVEHTFAGCEDRGFICYICSSVFTGPSGLLSHMEDIHGSNAKPYDCSRCAAKFFFRAELDHHAVMHEPLAKEIEKPSIHEPEISVREGSVSPNIKKEVNGESEDEEEEEYIEVEEPRTETYKQENGESPSKEEEEKNNEEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -