Cbre000531.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070085.1:5506735-5520678[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.001 0.04 14.2 3.1 1 23 244 266 244 266 0.97 2 11 0.0018 0.067 13.5 8.1 1 23 272 294 272 294 0.94 3 11 8.1e-05 0.0031 17.7 5.7 1 23 300 322 300 322 0.98 4 11 0.00018 0.0069 16.6 2.4 1 23 328 350 328 350 0.97 5 11 1.1e-05 0.00041 20.5 0.8 1 23 356 378 356 378 0.97 6 11 1.4e-05 0.00053 20.1 0.5 1 23 384 406 384 406 0.96 7 11 0.00015 0.0056 16.9 0.8 1 23 411 433 411 433 0.96 8 11 0.0012 0.045 14.0 0.1 6 23 444 462 439 462 0.89 9 11 0.035 1.3 9.4 0.1 3 23 566 586 565 586 0.98 10 11 0.44 17 5.9 5.3 1 23 695 717 695 717 0.95 11 11 0.0093 0.35 11.2 5.4 5 23 730 748 721 748 0.87
Sequence Information
- Coding Sequence
- atgtGCGCCGCTCAGACAAACACGTCAAATCAAACGTTCGGATATACATGGGGCTTCGCGGACAATTCTCGCGGCGAAAGTGTCGTCGAGATCTCGCCAAATATCAACTATACAGTCAGTGATGCGATGCCATACTTGCAGTTGGCGGATGGCAGCAACATCATCATACAGAAACAGGATACAAAGGGTAACATCACGCATACCAACAAGACCGGCGTGCGACGTATGCTGGTAGTGAACAGCGCCGATGCCTTTCCGCAAGGAACAACACAGAGGGTCATAACGACGTCGGGAGGCGCCGCAACAGTGACACATCACAAGAAACACGATGTTCTAAcgaCAACAAATGGTTTGATTGATTCAAAACACACGACAGTCTTGACGTCGAGCGGCAAAGCAGCGGGCGCCACGCAATTCATGAGCCCCTTTGGCCCGATTCAACTTACCGCCGAGGAATGCAATGAAATTCTGTTGAAGCGACAAATGAATGccgcaacgacaacgacgccgCAACACACGGCAACCATTAACACATCGAACGACGGGCATCACTCGATTTCGGTGCAAGTGCAAAAAGTCATTCAGGGCTTGGAAAATGATGAGTCGGAGAGTCCGACGACAATAACGCATTGCAAAATTGAACCAAACATGGAAATTACGCCGAAAATTGAGCAAACTGACGAGATGCAAGACAGTATGAACAATTCGGCACAAGCCAAGGAACGTCCTTATGCGTGCGatcaATGCGGCAAATCCTTCTTGCTAAAACACCATTTGACGACACATGCTCGTGTCCATACCGGCGAACGCCCTCATGTTTGTCCCCATTGCGGCAAGGATTTCGCTCACAAACATTGCTTGAACACCCATTTGGTGCTCCATTCAACTGAACGTCCTTTCCAATGTCAGGAATGCAAAAAATCTTTCACGCTCAAGCATCATTTGTTGACACACGCTCGCGTTCATAGTCGCGAAAGACCTTTCGTGTGTCAAGAATGCGGAAGATCGTTCCCATTGAAACGTCATTTAGTGACTCACACGAAATTTCACGCCGGAGAACGACCTTTTGTGTGTGAAGagtgCGGAGAATCATTCGCTCAAAAGGATCATCTTGTAATGCATTCACGTTTTCATGGGTCTGTTAATCCATTTGTTTGCAatgagtgTGGACAAACGTTCCCCCGAAAATTCCAACTTGTGAATCACGGAAAGCTTCATGGAAAAGTTCCGCATGCTTGTACGGTTTGCGGCAAAGAATTTTTGCAGAAACGAACGTTAGCAGCTCATATGCGTCTTCATACGGGAGATCAACCGTATCCTTGTATCGCTTGCGGCGAAGGTTTCCGTACCAAAAGTGAACTTAACCAACATAATCGCTCCGTGCACAATGGCGTGAATCCGAATTCGAGCAATACGACAATTGTGCCCGTGAATCGTATTGTGACGACAGTTGCTGCGAgtcaacagcagcagcagcaacaacagcaaacGCAGCAGATTCAGATTCAACAGgttcaACCACAGCAAATTCAACAAGATCATCATACCGTCGAGATCCAAACCGTTCAACATCATGTCACGCAAAATCATCAACCGCAAACAATTACCGTCGTTAGCGGCAATCAAAATTTGCTCCATCAGATCAGTCAAGCACAGCAACAACAAGAGGCTTCGCCGCAACGCCCTCAGCACGGATGTCGTGAATGCGGATCTGCATTCCTTACCAAAGAAGCGCTCGCCTTGCATATGCGCCTTCACACGGGAGACAAGAGTCTCATGACAGACTTGTGTGCATTGACAGCTGCGATTCCCGGATTGTCCTTCCAAGgagTTCCAACATCGCCCGTTCCCGTGCAAATTGTGTCATCAACAGGACAAGTTATCGGCCAAACGCAAATCAGTCACAGTTCGCCGCAACAACAAGTTCAAGTACAAACGACGCAAACGTCTCAACCGACACAAATCAAGTACGAAACGGTACAAATGATTCCGCAGCAACAAGTACAAgtgcaacagcagcagcaacagcaaccGCAAACGCAGACAATTATCCAACAAGTGACGCAACAGAAGCCAAAATCGCATTTCTGTGGGCATTGTCAAAAAGGATTTGCTGCTAAACATGGTTTGTTATTGCACAATAAACGTCATCCGAATGGTACTTGCACTATGAGATCACACGTTTGTGAATGCGGAAAGGCTTTCTTCCAAAAGAATCATCTCATGTTGCATCAGAGACAACATATGGAGCAAAAGCCTAACATTCAACAAttGCAACAAGTTCAAGGCAACGAAGTAATCGTCACGCAAGGCGGTCAACAAATCCAAACGAACGGCGCTCATCAACAAGGACAAATTCGCATCATCAACAACCAACAGATGCAGCTACAGGTGTTGCCAGACAACAACCAGCAAGTAATTAAATACGAAATTATCCAGCACGAGGGTCGCCAGTCGATTGAATGA
- Protein Sequence
- MCAAQTNTSNQTFGYTWGFADNSRGESVVEISPNINYTVSDAMPYLQLADGSNIIIQKQDTKGNITHTNKTGVRRMLVVNSADAFPQGTTQRVITTSGGAATVTHHKKHDVLTTTNGLIDSKHTTVLTSSGKAAGATQFMSPFGPIQLTAEECNEILLKRQMNAATTTTPQHTATINTSNDGHHSISVQVQKVIQGLENDESESPTTITHCKIEPNMEITPKIEQTDEMQDSMNNSAQAKERPYACDQCGKSFLLKHHLTTHARVHTGERPHVCPHCGKDFAHKHCLNTHLVLHSTERPFQCQECKKSFTLKHHLLTHARVHSRERPFVCQECGRSFPLKRHLVTHTKFHAGERPFVCEECGESFAQKDHLVMHSRFHGSVNPFVCNECGQTFPRKFQLVNHGKLHGKVPHACTVCGKEFLQKRTLAAHMRLHTGDQPYPCIACGEGFRTKSELNQHNRSVHNGVNPNSSNTTIVPVNRIVTTVAASQQQQQQQQQTQQIQIQQVQPQQIQQDHHTVEIQTVQHHVTQNHQPQTITVVSGNQNLLHQISQAQQQQEASPQRPQHGCRECGSAFLTKEALALHMRLHTGDKSLMTDLCALTAAIPGLSFQGVPTSPVPVQIVSSTGQVIGQTQISHSSPQQQVQVQTTQTSQPTQIKYETVQMIPQQQVQVQQQQQQQPQTQTIIQQVTQQKPKSHFCGHCQKGFAAKHGLLLHNKRHPNGTCTMRSHVCECGKAFFQKNHLMLHQRQHMEQKPNIQQLQQVQGNEVIVTQGGQQIQTNGAHQQGQIRIINNQQMQLQVLPDNNQQVIKYEIIQHEGRQSIE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -