Cbre008853.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:32306831-32309735[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.2e-06 0.00016 21.7 2.7 1 23 159 181 159 182 0.95 2 13 0.75 29 5.2 0.1 1 23 269 292 269 292 0.93 3 13 0.0006 0.023 14.9 1.2 2 23 298 320 297 320 0.97 4 13 0.015 0.57 10.6 3.0 2 23 328 350 327 350 0.94 5 13 0.00072 0.028 14.7 1.0 1 23 356 378 356 378 0.96 6 13 0.0043 0.17 12.2 0.4 1 21 384 404 384 405 0.94 7 13 0.00032 0.012 15.8 4.9 1 23 556 579 556 579 0.98 8 13 0.011 0.4 11.0 0.1 1 23 668 691 668 691 0.97 9 13 7.1e-05 0.0027 17.9 5.7 1 23 696 719 696 719 0.97 10 13 0.00067 0.026 14.8 2.3 2 23 727 748 726 748 0.97 11 13 8.5e-07 3.2e-05 23.9 1.4 1 23 754 776 754 776 0.98 12 13 1.6e-05 0.00062 19.9 3.1 1 23 782 804 782 804 0.98 13 13 2.4e-06 9.1e-05 22.5 1.5 1 23 809 831 809 832 0.96
Sequence Information
- Coding Sequence
- aTGGATCCCGCAAATTTAGAGGCCTTATGTCGTCTCTGCTTGcaaaaattgccgaaaaaacGCAAGGAATGCTACGAGTTCGACGAGTCCTTGGAAAAATATCCCGACACAACGTTCGCCGAAGCATTTCTCAGCTGCACGGGATGCAATATCCAGGAGCATGAGCCCCAACATATGTGTTTGTCATGCGGAACGGAGCTAATGATGGCCTTCGATTTACGTGTCAAGTGCTACCAAACGCAAGAAGTGCTCGATAAGCTATTTGAGACTGCCGTCAATGAGGAACCTTTGCTCGAAGAGCCTCCTTTCGAGTATGTCGAAGGCATTCCGACATCAAATTACGACGAATACGGTCAAGAAAGCATCATGGATGAGGAAATCGAGTACAAACCGGAGATAAAACCCACAAAAATTGTCGTcattaagagaaaaaagtcaGATTTGAACATAAAATCCCTGCCAGAAGTCATGAATTTCCCCTGCGAATACTGCGGAACGACTTTTAGAACTGAATCTGCGCTTAGAATTCATCACGAAACACATCATTCGGACCAAAAACGACTTGAATGTCCAAATTGCCTGCAACTTTTCTTCCCAACGACGTTCGAACCACACATTAAAGTCTGTACGATGCTTGATGTCGACTCAAAAAACGTCTCCGATAAACGACAAAAGGCCAAAAACTCTTCAAATCGCAAAGAAGTGTGTCCCATTTGCGCGGAAATACGTTCGCAGTACCACATTAAATGGCATATTGAGCGATCGCAGCAAATAGACGCCGAAGGCAACGTCATCACGCATCCTTACATCTGCGATATTTGTGGGGCACGAAAAACGGCGAAAAGTTACATCCTCCAGCACATCCGGAACGAACATTTGAACAAATTCGTGAAATGTCGTTACTGCCCGGCGGAATTTAAGCATCCGAGTACGCTTTATTCGCACGAAAGACGCGAACATACCGACAAATGTCCCCTGCTAAAGTGCAAATATTGCGATTTTATGTCGGCGACGCACTCCTCGTTGCGAGTTCACACCTACAGCAAGCACACGGGCGAGAAAAAACACGAATGCAACATTTGCTTTGCGAGATTCGTGACGAAATGGAAGCTGCAGGAGCATATGGGGAGTCATAGTACGGAAACGCCGTTCTCTTGTGAGGTCTGCGATGGCAAATTTAAGACGAAAGAAGGCGTGCGACGACATCAAACGAAGatgacGGAGACAAAAACGTGTCGTGCATGTCTCAAATCTCTCACGGATGATGGAAGAAATTTATCAGATCGCATTGAAAAAACGGAATTAGTCATTTCCTATCGTCAAGCCTTTGAAAAATGCTCTGGATATGAGGTCACAGATGACGAACCACAAGAAATTTGTAACGAATGTGCGTCAGAATTGCGATTTTCGCttaatttcaagcaaaaatgtgaagaaacTCAAGGAAAATTGGCAAATTGGTTGAGATGCAAGCAAGAAATTCGAGAAACTGTCgtcaaaatggaaatttttgcgGAAAACATCAGTGTTGAAGAGGATTTTGATGATAGGCAAGatgattttagtgaaaaacaAGATGATGTAGCTGAAAAACAAGATGATTTAGCTGAAAAACAAGTCGATATTACTTGTAAAAAAGACGATTCGAGTAAACAAATTAAGAATTTCAAGTGCTCTCTATGCGGAAAATGCTACAAAACTCGTCAAAAAATGTTGGATCACATGAATCGATCGCATTTGGAGAACAAAACCGAAACCTGTGAGTACTGCAAGCGGAAACAACATCCACAAGAGCTCGAAACTCATTTAAACCTTTGTTATATCGCGAGACTGAAGACAGGGAAGACAAAACGAAAAACCGGTTACACGAAAAAagagtcaaaagtaaaaaattgcaaaactcGCACCATCAAAAGCCGCATTTGTCCAATTTGCGGCATGCTGGAGTCCATTTCTCACATTTCCATGCACATTGCATGCAAAATGCCGATAACCAAGAATTTTGTTTGCGACATTTGCGATGCTCAATTGACAACGATTCAAAGTATTCGGCGTCACATGTCGACAGTTCACCTGAAACTCGGTCACAAGTGCAAAAAATGCTCGGAATCCTTCGAAACGTCGCATCAACTGAACAAACACACGCGAATCGTGCATCCTGGCGTCTTGGCAATCATCAAATGTGAATTTTGTGGCGTCACATTCAACAATTATGCGTGTCTCCGGAAGCATCGTGCCCGTCATACCGGCGAAAAGTTCCATAAATGCAACGTTTGTGGCAAAGGGTTCGTGCAAAGTACGTCGCTGAAGAATCACATGGCGTCGCACAGCGATGAGCGTCCCTATCCGTGCGAATATTGCGGCTTGGCGTTCAAAACGACGAAACATCTGCGAAATCATCGGAAAAATCACGAAACGCACGAATACGAGTGCCCGGTTTGcgagaaaactttttccacGAATCAGTATTTGAGGGAGCATCTGGCGAAACATCATCCGGAGTACGAGTTGCCGCCCAAAGGAGCgattatgaacaaaaaataccgGATCATGATGAAGGAAAAGCAGTTGCGGGAGGAGGCGTTGAGGCAGGGAATGCACTCGAAGCAAGTCGAGAAGATTGTTGTCACGGAGGTGCCGTCGTTGGAGGAAATGTTGCTCGTGCAGAAGCATTTTACGGAGAAATAA
- Protein Sequence
- MDPANLEALCRLCLQKLPKKRKECYEFDESLEKYPDTTFAEAFLSCTGCNIQEHEPQHMCLSCGTELMMAFDLRVKCYQTQEVLDKLFETAVNEEPLLEEPPFEYVEGIPTSNYDEYGQESIMDEEIEYKPEIKPTKIVVIKRKKSDLNIKSLPEVMNFPCEYCGTTFRTESALRIHHETHHSDQKRLECPNCLQLFFPTTFEPHIKVCTMLDVDSKNVSDKRQKAKNSSNRKEVCPICAEIRSQYHIKWHIERSQQIDAEGNVITHPYICDICGARKTAKSYILQHIRNEHLNKFVKCRYCPAEFKHPSTLYSHERREHTDKCPLLKCKYCDFMSATHSSLRVHTYSKHTGEKKHECNICFARFVTKWKLQEHMGSHSTETPFSCEVCDGKFKTKEGVRRHQTKMTETKTCRACLKSLTDDGRNLSDRIEKTELVISYRQAFEKCSGYEVTDDEPQEICNECASELRFSLNFKQKCEETQGKLANWLRCKQEIRETVVKMEIFAENISVEEDFDDRQDDFSEKQDDVAEKQDDLAEKQVDITCKKDDSSKQIKNFKCSLCGKCYKTRQKMLDHMNRSHLENKTETCEYCKRKQHPQELETHLNLCYIARLKTGKTKRKTGYTKKESKVKNCKTRTIKSRICPICGMLESISHISMHIACKMPITKNFVCDICDAQLTTIQSIRRHMSTVHLKLGHKCKKCSESFETSHQLNKHTRIVHPGVLAIIKCEFCGVTFNNYACLRKHRARHTGEKFHKCNVCGKGFVQSTSLKNHMASHSDERPYPCEYCGLAFKTTKHLRNHRKNHETHEYECPVCEKTFSTNQYLREHLAKHHPEYELPPKGAIMNKKYRIMMKEKQLREEALRQGMHSKQVEKIVVTEVPSLEEMLLVQKHFTEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -