Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: Znf219
Assembly: GCA_036172545.2
Location: CM070085.1:6699851-6702552[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0025 0.096 13.0 0.3 1 23 182 204 182 204 0.99

2 11 3.4e-05 0.0013 18.9 3.3 1 23 210 233 210 233 0.96

3 11 2.7e-05 0.001 19.2 0.8 1 23 239 261 239 261 0.99

4 11 2.3e-06 8.7e-05 22.6 0.4 1 23 267 289 267 289 0.98

5 11 2.1e-07 8.2e-06 25.8 1.1 1 23 295 317 295 317 0.99

6 11 3e-05 0.0012 19.0 3.7 1 20 323 342 323 346 0.95

7 11 0.88 34 5.0 6.4 1 23 352 372 352 372 0.92

8 11 5.9e-06 0.00023 21.3 0.4 3 23 380 400 380 400 0.99

9 11 2.8e-05 0.0011 19.1 1.1 1 23 406 428 406 428 0.99

10 11 0.022 0.83 10.0 1.9 1 23 434 460 434 460 0.92

11 11 0.011 0.43 11.0 1.5 1 19 466 484 466 486 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0025	0.096	13.0	0.3	1	23	182	204	182	204	0.99
2	11	3.4e-05	0.0013	18.9	3.3	1	23	210	233	210	233	0.96
3	11	2.7e-05	0.001	19.2	0.8	1	23	239	261	239	261	0.99
4	11	2.3e-06	8.7e-05	22.6	0.4	1	23	267	289	267	289	0.98
5	11	2.1e-07	8.2e-06	25.8	1.1	1	23	295	317	295	317	0.99
6	11	3e-05	0.0012	19.0	3.7	1	20	323	342	323	346	0.95
7	11	0.88	34	5.0	6.4	1	23	352	372	352	372	0.92
8	11	5.9e-06	0.00023	21.3	0.4	3	23	380	400	380	400	0.99
9	11	2.8e-05	0.0011	19.1	1.1	1	23	406	428	406	428	0.99
10	11	0.022	0.83	10.0	1.9	1	23	434	460	434	460	0.92
11	11	0.011	0.43	11.0	1.5	1	19	466	484	466	486	0.96

Sequence Information

Coding Sequence: atgaAAGTCTTAACACGAAGAAATGCGGCTTTAAAAAATACCGCAGTAACGTCTCGTGCGATACGAGCCTCTGTTATCAATCGTCGTAATTCTGAAAAAACTGCGGAAAAATCGAAACGTACTACAAAAGTAGCTAAAGATGTCGCAAAAACGAACGAGGAAGATGAAAATGCGAAAACAACGACAGAAAAGAccaaagaaaatgtaaaaccaACAACTACAGGGAAAAAACGCGGAAGGCCATTCAAGAAAGATCAACTTTCTTCGCCATCGAAGGAAACAACAAAACCAAAGACAACGAACTCAGTGTTACAAaccaaagaaaataaatccgACAAAACAGCTCCTTCAGAGGAAAATTCTTCGCCATCAAAGGCGGCAACAagaacaagaacaaaaaagaatGAAGCAGAAAAATCGGCTGAAGTTGTTGAAaagtcaattgaaaaaaataacaatgaaaCAAGTAATGGCTTGTTAACCAAAGGACCATTCAGCGGAAGTCAAACCTTGTCAGAAACCAGTAAGAAAAGTGATCGAAAATATCAATGCGGAATTtgtatgaaagtttttttgggATCTAATGATTTGAGAAAACATCTTCGAATTcatagcgaTGAACGTCCTTATTCTTGCCCACACTGCGATAAACGATTCCGTCAAGGAGGATGTTTGAAAAATCACATAGCTTCGCAACATGGAACTGATACTGTCTACACTTGCGATTATTGTTCCAAGACTTTTCCGATAAAGGAACGCCTGAGATTACACATTCGTATTCATACGGgtgaAAAGCCGTACAAATGTGATTATTGTCCAAAAACATTTGCTCGTGGCGGGCAACTCACGCAACATTTGGTTACACACACCGGTTTGAAGAAATTCAAGTGCGATAATTGCGGGCAAAAGTTTTCGTCAGCTGCTAATTTGAGATTGCATCAAAAGACGCATTTAGATGAAAGAGATTTCACTTGCCATCTTTGCGGAAAAGGGTTTTATCGACCTGATGCTTTGAAGAAACACATTTCGTGCTATCATCATAACATTAAGGCTTTTCACTGCAagatttgcaataaaatgttcaaaggaCATTTGCCGCAACATAAGCGCACGCATAAACATATCAAGAAACATGGGTGTTCGACATGCGGAGCAACGTTCTCTCAACGATCGCAACTCGTTGTTCATCAGAGAATTCATTCGGGAGAGAGACCTTatagatgTCAAGTTTGTTGGCAAGCTTTTGCTCATAGTTCCGTATTAAAACTGCATATACGTAAACATACGGGAGAAAAACCATTCAAATGTCCCATttgtgTTCAAACGGGCCTTGGATTCTCCCAATTGCCACACTTGAAGAAACATTTAAAGTCAATTCATGGACAAGATAAGCCCTATATGTGCGAAAATtgcaaagaatttttcaaaacaaagtaCGATATTCAACAACACTCTTTCGAATGTGTCAAAAAGGAGACAGTTGCAAGTGTTGAAGAGCTCATCGATCGAACAattcgaAACAACCATGCAAGTGTTGAGCCTCCCATGCCCGTCGCCCGAATGCGTCTTTTGATTGCAATTTTGCTCAAGAAAATCTCGACAGATGAACGTTTGCGACAACTTGGCTACGAAAAACGTCTTATCGATAATGTTCTGATTGATTCTCTCAAATGTGCAGGACGCAATGCTTGCGAATCGATGGATATGACAGAAGCGCAACGCTTGAAGACAAATGTGCAAGAGTTTCTCGAATGGACTGTTCCCGCACAGTATATGGAAAACTTTAAGCGACAACATCGCAGTACCGAAGAAATTCTTGAGGAATTGactaattaa
Protein Sequence: MKVLTRRNAALKNTAVTSRAIRASVINRRNSEKTAEKSKRTTKVAKDVAKTNEEDENAKTTTEKTKENVKPTTTGKKRGRPFKKDQLSSPSKETTKPKTTNSVLQTKENKSDKTAPSEENSSPSKAATRTRTKKNEAEKSAEVVEKSIEKNNNETSNGLLTKGPFSGSQTLSETSKKSDRKYQCGICMKVFLGSNDLRKHLRIHSDERPYSCPHCDKRFRQGGCLKNHIASQHGTDTVYTCDYCSKTFPIKERLRLHIRIHTGEKPYKCDYCPKTFARGGQLTQHLVTHTGLKKFKCDNCGQKFSSAANLRLHQKTHLDERDFTCHLCGKGFYRPDALKKHISCYHHNIKAFHCKICNKMFKGHLPQHKRTHKHIKKHGCSTCGATFSQRSQLVVHQRIHSGERPYRCQVCWQAFAHSSVLKLHIRKHTGEKPFKCPICVQTGLGFSQLPHLKKHLKSIHGQDKPYMCENCKEFFKTKYDIQQHSFECVKKETVASVEELIDRTIRNNHASVEPPMPVARMRLLIAILLKKISTDERLRQLGYEKRLIDNVLIDSLKCAGRNACESMDMTEAQRLKTNVQEFLEWTVPAQYMENFKRQHRSTEEILEELTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -