Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: -
Assembly: GCA_036172545.2
Location: CM070086.1:15575823-15579757[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.8e-05 0.0007 19.7 0.8 1 23 137 159 137 159 0.97

2 15 8.7e-05 0.0033 17.6 0.4 3 23 167 187 166 187 0.99

3 15 5e-06 0.00019 21.5 0.4 1 23 317 339 317 339 0.98

4 15 0.003 0.12 12.7 3.9 1 23 345 367 345 367 0.97

5 15 0.0011 0.043 14.1 1.0 1 23 414 436 414 436 0.97

6 15 1.8 69 4.0 0.1 1 23 460 482 460 482 0.93

7 15 0.038 1.5 9.3 0.1 2 23 489 511 488 511 0.94

8 15 2.2 83 3.7 1.4 2 19 519 536 519 537 0.95

9 15 0.0036 0.14 12.5 3.9 1 23 547 569 547 569 0.97

10 15 0.76 29 5.2 0.8 2 23 575 596 574 596 0.93

11 15 9.2e-06 0.00035 20.7 2.3 1 23 602 624 602 624 0.98

12 15 0.00096 0.037 14.3 0.2 3 23 632 652 630 652 0.97

13 15 2.3e-05 0.0009 19.4 0.2 1 23 658 680 658 681 0.95

14 15 0.058 2.2 8.7 1.0 1 23 695 717 695 717 0.95

15 15 0.0045 0.17 12.2 0.1 1 23 986 1008 986 1008 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.8e-05	0.0007	19.7	0.8	1	23	137	159	137	159	0.97
2	15	8.7e-05	0.0033	17.6	0.4	3	23	167	187	166	187	0.99
3	15	5e-06	0.00019	21.5	0.4	1	23	317	339	317	339	0.98
4	15	0.003	0.12	12.7	3.9	1	23	345	367	345	367	0.97
5	15	0.0011	0.043	14.1	1.0	1	23	414	436	414	436	0.97
6	15	1.8	69	4.0	0.1	1	23	460	482	460	482	0.93
7	15	0.038	1.5	9.3	0.1	2	23	489	511	488	511	0.94
8	15	2.2	83	3.7	1.4	2	19	519	536	519	537	0.95
9	15	0.0036	0.14	12.5	3.9	1	23	547	569	547	569	0.97
10	15	0.76	29	5.2	0.8	2	23	575	596	574	596	0.93
11	15	9.2e-06	0.00035	20.7	2.3	1	23	602	624	602	624	0.98
12	15	0.00096	0.037	14.3	0.2	3	23	632	652	630	652	0.97
13	15	2.3e-05	0.0009	19.4	0.2	1	23	658	680	658	681	0.95
14	15	0.058	2.2	8.7	1.0	1	23	695	717	695	717	0.95
15	15	0.0045	0.17	12.2	0.1	1	23	986	1008	986	1008	0.95

Sequence Information

Coding Sequence: atggaacaaaatatCGAGTGTTACACAACGTTGGAGTGGACCACGGAGGAAGTTCCGCACGAAGGACAAGCAAATTCCGGGAGTTATATCGTGGAAACgggaaatttgaatgaaattgacCCGAATCACTTGATTTACATGACGGAAGACGGGCAACGGATCGGCATGGATGACCTTATCGAGGAGGAACAAGGCAGTCCGCAGGAAGATGGCACTTCCGTTGACACATATACGCAAGAGGAATGCGAAATTACGGAAGAAGTAGTCACCCAGGATTGGGTTCAAGGCGACGATTGTGTCCAAGAAGTCACGGTAATCGATCAAATCGACCCCGTAGAGCAGAATTTAAACGCTTCCGATATAATTCCCTTGCCCGAAGCACAAGACGAGTACACAGCGTCACGCCCTTACCCCTGTGACTTTTGTTCCCGTCGTTTTCGCAAGAaagcaaatttaatgaatCACATGATTGCCCATCAAAATGATCGTCCGCACGGATGTAACTTGTGCGGAGCCCGATATATCCGAAAAAGTGACTTATTGAACCACTTGAAGACCCATGCCTACACCGAAGACGGTTACAACCAAGAAGATCAGGATCTGGTGAACTTTTTGGACGAAGAATTGAACGACAGTGCCAACAGAAATTCGCATAGCGGCAAGATGAACATCGATTTGGAAGAACTTTTGCTTAGTCCAGGCACTTTTAACAGTTCAATCAACTCTTTTTCGCACCAACAGCGCTCCAGTAACGCAAATCGCATGAAAAAACCCATGAGTCGTCCGATCACGAAGGCAAGACAATTGCCCCTGCACAGtacaaaagtacaaaaaaagagaCCAAAACCCAAAACGCACACAATGCGGATGCCAACAAAGCTGAATGTGAGTAACGATGAGGCTGAAGAGGCACCTACGAAGTTTCCCGTTACAAATCCGTCAAAACCGTTCGTTTGTCAAAAGTGTGGAGTGGCATTTGCGCGATCCAAGGCACTCACGTCGCATATGAGATTCCATACAGGTGATATTTTGCACGAATGCACCGTTTGTGGGCAACAATTTTACGATAAAGTGCTTTATCAGAAGCATCATGCGAAGCATTTTGACGAAACAATCGATCCGCCGGATCTAGATTCGTTATCGACGTTCAAAGAGCAACCTGTTGTCGTGAAAGACGAATATGATGAAgaagcAACTGAATCCGAACGAGAAGTCGGCGGAAACTACGAAGACACACTATTCGAATGTCAAATGTGCCTAATTTCCTTCCATCGCGCCgatttattcgaaaaacaCATGATGGCTCACGAAACTTCCGctctcatcaaaaaatctcacgaCTTTAGCAACTCTTCGTTAGACGTTTCCCGCGAAGGTCACTTTTGCAACGTTTGCGGCGATCAATTCGAAGAAGCCCTGGATTTATTGGCACACGCAGAAGTTCACGCGAGATTCCAACCGCTCAAGTGCCTTTTGTGCGGCGAGCAATTCAACGTCGAGTCCGAAATAAAAATGCACATAAACGAGATGCATCGCGCAGAATTGACTGAAAACACGTGTCGCTTATGCGGAAAGCTATGCAAAGATGGTCGAACCTTGATGCGTCATTCGTGGGATCATTCAACGGGCGACGGGAATTTTTCGTGTGCTCGATGTGCGAAAACGTTTCACAACAAAGCCCGTCTCAAGCGACACATGACTTCGCATAAAAACAAAACCGTGATGTGTGATACGTGCGGCAAGGAGCTGCAAGATGGGCGAAGTTTGATGAATCACAAGCATTTGCACACGAAAAGCAACCAATTTCACTGCACGGAATGCGGCAAAACGTTCGGAAGTCGCAGTTCGCAGCAAATTCACATGCGAATTCACACCGGAGAGAAGCCCTATGGGTGTCGTTATTGCGAAAAGGCCTTTGCGGATGGCGGAACATTGCGAAAACACGAGAGAATTCACACGGGCGAGAAACCCTATGCATGTCCCGTGTGCCCACGTGCCTTTAATCAACGTGTTGTCTTGCGCGAACACATCCGCTCGCATCATTCAGCTCCTGACCTGAAACTAGGGACTTCTGTGGCGCCCTATTTCTGTCCCGTTTGTTGTGATTCCTTCACCAATTCGCAAGACCTCATCAAGCATCTCATTGAACACAGCGATGCCAATACCCAAGCGAAGCGACAACCCCTACAAGGTCCCCGCAAATACAAAAGACGTCGAAATTTGGAAACTTTCGTCGGAAAACGCGCAAATCCCGTTCGCAAAAGTTCCTCCATGGATTTCGACGACGACAACTTGGATGACGAAACCACGACGTCGCAAGAAATGTCGATCGAGGACTACGCCGCCTACAGTTTTCGTACATTAGTGCCATTAAAACCGATTCTCGAGGATTTCCGTCTTCCGGAACAGTTTGTGCCGGAAAATGAGCGTCCCAAAGCCGTTTTTAGCAATAACTCCAAGACATCAAGACCAAAGATGATCCACACAGAAAAAACGCGAGTCGCTACTAATGATGGGAGTAAGAGGAAAACACGTTCGTTCATCAGCAAGACAACCAAAGACGTGGATTATTTGACTTTGGCACCGCCTCCGTCGAAATTGAAGCCCGATGACGAATCGTTTCCCTTGCTGGACGACGGAAAACCCTTGACTGTCGATGCGCCATTAACTGTGGATGAAGAACTTCTGCGAGAAATCGGCAAAtccacgaaaaatttcaacagtGACGTCGTCAATGACTTGAAAGAGATCCTTCAGTCGCCCGCGAAAGTTCCAAAAGTCGAAGTAGAAGAGGAAGAAAGTCCAGGAACAACGAGACGTTCGCGTCGTTCTATCAAACCAACGTTAAAAGCAATGGAATCTCCCTCCATTCGCACGTCTTATAGCAGTCGCATTCGCATCCAACCACGCAAAGAGGTAGAAATCAAACAAGAAGTTGATCTGGAAGACGAGCAACACGACTGCGAAATGTGCGGAGATAGTTTCCCGTCAAAGGGATTGTTGTTAGCACATGCCCAAATTCATatgtag
Protein Sequence: MEQNIECYTTLEWTTEEVPHEGQANSGSYIVETGNLNEIDPNHLIYMTEDGQRIGMDDLIEEEQGSPQEDGTSVDTYTQEECEITEEVVTQDWVQGDDCVQEVTVIDQIDPVEQNLNASDIIPLPEAQDEYTASRPYPCDFCSRRFRKKANLMNHMIAHQNDRPHGCNLCGARYIRKSDLLNHLKTHAYTEDGYNQEDQDLVNFLDEELNDSANRNSHSGKMNIDLEELLLSPGTFNSSINSFSHQQRSSNANRMKKPMSRPITKARQLPLHSTKVQKKRPKPKTHTMRMPTKLNVSNDEAEEAPTKFPVTNPSKPFVCQKCGVAFARSKALTSHMRFHTGDILHECTVCGQQFYDKVLYQKHHAKHFDETIDPPDLDSLSTFKEQPVVVKDEYDEEATESEREVGGNYEDTLFECQMCLISFHRADLFEKHMMAHETSALIKKSHDFSNSSLDVSREGHFCNVCGDQFEEALDLLAHAEVHARFQPLKCLLCGEQFNVESEIKMHINEMHRAELTENTCRLCGKLCKDGRTLMRHSWDHSTGDGNFSCARCAKTFHNKARLKRHMTSHKNKTVMCDTCGKELQDGRSLMNHKHLHTKSNQFHCTECGKTFGSRSSQQIHMRIHTGEKPYGCRYCEKAFADGGTLRKHERIHTGEKPYACPVCPRAFNQRVVLREHIRSHHSAPDLKLGTSVAPYFCPVCCDSFTNSQDLIKHLIEHSDANTQAKRQPLQGPRKYKRRRNLETFVGKRANPVRKSSSMDFDDDNLDDETTTSQEMSIEDYAAYSFRTLVPLKPILEDFRLPEQFVPENERPKAVFSNNSKTSRPKMIHTEKTRVATNDGSKRKTRSFISKTTKDVDYLTLAPPPSKLKPDDESFPLLDDGKPLTVDAPLTVDEELLREIGKSTKNFNSDVVNDLKEILQSPAKVPKVEVEEEESPGTTRRSRRSIKPTLKAMESPSIRTSYSSRIRIQPRKEVEIKQEVDLEDEQHDCEMCGDSFPSKGLLLAHAQIHM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -