Cbre002103.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- zfh1
- Assembly
- GCA_036172545.2
- Location
- CM070085.1:21415463-21417274[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 2.5 94 3.6 0.6 1 23 197 221 197 221 0.90 2 12 0.013 0.49 10.8 3.6 3 23 228 249 227 249 0.89 3 12 0.001 0.04 14.2 0.4 1 23 262 285 262 285 0.92 4 12 8.5e-06 0.00032 20.8 2.9 1 23 294 318 294 318 0.98 5 12 1e-05 0.00039 20.5 3.4 1 23 325 347 325 347 0.98 6 12 1.7e-05 0.00066 19.8 0.9 1 23 353 375 353 375 0.96 7 12 7.8e-05 0.003 17.7 0.2 3 23 383 403 381 403 0.98 8 12 0.00015 0.0059 16.8 0.9 1 23 409 432 409 432 0.96 9 12 0.00022 0.0082 16.3 3.5 1 23 438 461 438 461 0.97 10 12 1e-05 0.00039 20.5 0.5 1 23 467 489 467 489 0.98 11 12 1.6e-06 6.2e-05 23.0 1.9 1 23 495 517 495 517 0.97 12 12 0.0015 0.055 13.7 0.6 1 23 523 547 523 547 0.92
Sequence Information
- Coding Sequence
- ATGTCAAATGCAGCGGGAGTCgttaaattcaacattttgaaTCCAGGTTTCACTCAATCTCAGTCCTTTGCCCTCGCAAGTGGTAGTTCTGTCGAAAATGTAGATGTTTGTTTCCTTTGTTGTTCCGATATTGAACAGGGAGTTATTGAAACTGTCtttagTCCCGATGAAGTTGCTTTACATAAAATCCTATTGGATTCATTGAATATCCAGCTGTCGCCTGAAACTAAAATTCTTGCACGATTATGCAAAACTTGCATCTCTCATCTGGAACAGTACCAAGAGCTCTTGTCACAACTGGCAAACATCAAATCTTTGCTGCAAATCGCTTATAAACGAGGTCAAAGTATTTTATCGAAGCGACAGAAATCAGATTTTACATTGCTAAAGAACACAGATTCCTACGGAacgacttttttaatttatcaacagCCCAAGGAAAGCACAATTCCCCAACTTTACATATCGGATGGACCAATTTTGGATGACCAAccggaaaattttgaagatctGGTTCAGTTGACGACCACAACAGTCGCGGATCTCGATCcaaaattaatgtttgaaCGCAAAACTGATTCCGGAAGTTATTTTTGCAAGCAATGTTcggacaatattttttacactCAAGACGAAATCCAATCACATCTTTTATCGGAACATGGATATGCGGTGGCAATTTGTAATATTTGCGATAATTGCTTCTCGGACAGCAATGAGTTGAATCTGCACAAAGTTAATTGTCATTCTGAGGTTCCGCCACTGGTTCCCTTAAAAAAAGACTTTAAATGtactttttgtgataaaattttcaaagaaaaagttttgctgGACGATCATCTTGCTGCGAGTCATAATTCTGAGTCGTCTTCTCGTCCCTTTAAATGTCCCCATGACGGATGCAGCAAAGATTTCACGTCGAAATATACTTTGACGACTCACATGAAAATCCACACCGATCGTCCACGACCCTATAAATGCACGGTTTgcgaaaaatccttttatcaTTCGCAAAATTTAGTGCAACACCTGAAACTCCATTCCAGCACCAAGGAATTTATTTGTTCCGGTTGCAATAAAGCCTTTAGCACGCAACACAACCTCGATGTCCATTTTATCGTCCACacaaagctgaaaaaattCGGATGTGCCATTTGTGACAAAAGATTTGCCCGCAAAGCGGAGGTTCGGGATCATGAACGAACCCATACCGGCGAAAAACCTTTTTCATGTGACTTTTGCAGTGCTACGTTCGCGCAACGATCCAACTTGCTGAGTCACAAAAGAGCAACGCATCTCAACGACAAGCGACATAAATGTTCGCAGTGCAACAAGGGCTTCAAACGACGTCGATTGCTGGATTATCACATAAAATCCGCGCACACGGGCGAACGGCCATATGCTTGTGATATTTGTAACGCCACTTTTGTGATTCCGGAACACTTTAAGAAGCACATGCGAATTCACACGGGAAAGAAACCGTTTACGTGCGAGCTGTGTAAACGGTCGTTCAGTAGCAAGGACAACTTGAAAGCCCACAGATTTGTGCATAGCAAGCAAAAACCGTACGAATGCATGGTTTGCGAAATGGGATTCATGAGAAAAACGCTGCTTTTTACGCATATGAAAAGTCAGGATCACGAGTCGGAGCATTTTGTGGTGAATGAGCCGAAAATCGGGGAAAAGGGAAATATTGTGATTGAAAAAACTGTCACTAAAATCGAGTTGAACCAGGAAGAAGATGATCAAAAGTAG
- Protein Sequence
- MSNAAGVVKFNILNPGFTQSQSFALASGSSVENVDVCFLCCSDIEQGVIETVFSPDEVALHKILLDSLNIQLSPETKILARLCKTCISHLEQYQELLSQLANIKSLLQIAYKRGQSILSKRQKSDFTLLKNTDSYGTTFLIYQQPKESTIPQLYISDGPILDDQPENFEDLVQLTTTTVADLDPKLMFERKTDSGSYFCKQCSDNIFYTQDEIQSHLLSEHGYAVAICNICDNCFSDSNELNLHKVNCHSEVPPLVPLKKDFKCTFCDKIFKEKVLLDDHLAASHNSESSSRPFKCPHDGCSKDFTSKYTLTTHMKIHTDRPRPYKCTVCEKSFYHSQNLVQHLKLHSSTKEFICSGCNKAFSTQHNLDVHFIVHTKLKKFGCAICDKRFARKAEVRDHERTHTGEKPFSCDFCSATFAQRSNLLSHKRATHLNDKRHKCSQCNKGFKRRRLLDYHIKSAHTGERPYACDICNATFVIPEHFKKHMRIHTGKKPFTCELCKRSFSSKDNLKAHRFVHSKQKPYECMVCEMGFMRKTLLFTHMKSQDHESEHFVVNEPKIGEKGNIVIEKTVTKIELNQEEDDQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -