Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: -
Assembly: GCA_036172545.2
Location: CM070087.1:11678356-11682936[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3e-05 0.0012 19.0 0.4 1 23 168 190 168 190 0.98

2 12 0.64 24 5.4 5.9 2 23 197 218 196 218 0.97

3 12 0.0022 0.083 13.2 0.4 2 23 223 245 223 245 0.97

4 12 0.011 0.41 11.0 3.1 2 21 303 322 302 323 0.95

5 12 0.045 1.7 9.0 0.3 1 23 332 355 332 355 0.96

6 12 0.0013 0.05 13.9 2.4 1 23 363 385 363 385 0.96

7 12 2.2e-06 8.4e-05 22.6 0.9 1 23 392 414 392 414 0.98

8 12 1.4e-07 5.4e-06 26.4 1.6 1 23 424 446 424 446 0.95

9 12 7.6e-08 2.9e-06 27.2 1.1 1 23 452 474 452 474 0.99

10 12 7.1e-07 2.7e-05 24.2 0.6 1 23 480 502 480 502 0.98

11 12 1.4e-07 5.2e-06 26.4 2.4 1 23 508 530 508 530 0.99

12 12 0.00032 0.012 15.8 2.8 1 23 536 558 536 558 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3e-05	0.0012	19.0	0.4	1	23	168	190	168	190	0.98
2	12	0.64	24	5.4	5.9	2	23	197	218	196	218	0.97
3	12	0.0022	0.083	13.2	0.4	2	23	223	245	223	245	0.97
4	12	0.011	0.41	11.0	3.1	2	21	303	322	302	323	0.95
5	12	0.045	1.7	9.0	0.3	1	23	332	355	332	355	0.96
6	12	0.0013	0.05	13.9	2.4	1	23	363	385	363	385	0.96
7	12	2.2e-06	8.4e-05	22.6	0.9	1	23	392	414	392	414	0.98
8	12	1.4e-07	5.4e-06	26.4	1.6	1	23	424	446	424	446	0.95
9	12	7.6e-08	2.9e-06	27.2	1.1	1	23	452	474	452	474	0.99
10	12	7.1e-07	2.7e-05	24.2	0.6	1	23	480	502	480	502	0.98
11	12	1.4e-07	5.2e-06	26.4	2.4	1	23	508	530	508	530	0.99
12	12	0.00032	0.012	15.8	2.8	1	23	536	558	536	558	0.98

Sequence Information

Coding Sequence: ATGGATTTAAAAGAAGTTACCGTActgaatttggaaaaaatctgTAGAATATGTCTGGAAGTACCGGAAGAAGCGATTCATTTGTCGACAATTGTTTATTCGACGTTTTTGCAGGAAGCGACTTCTTATGATTCGCAGTTAGCGGATTTGATTCAAATGAATatcagCACCGATGACATCCTTCCAAAGCAACTTTGCAACCCATGTGCCGTAAAACTGCaggaatttcacattttccgcacaaaaactctaaaaagtgaagaatacctccgaaaaattgttgaaaatatcGAAACAACCACAGAAAATGCCCCAGAAAATCCAACCAAAGTCCCTTACGAAACCCTCGATCACTATGACGAACCTTTTTACCAAAACGAGGAATATTTACTTAACGAAGAAACTTCTGACAAAAAAGAAATCGATCCAAAAACTTCAGAAACAAACCTTAAAGACGAAGTTTCTACAAAAcgaaacacaataaaaaattccgaaGCAAAATACGAATGTCCCGAATGCAAAAAACCCTTCGTCAATTTGAAAGCCCAACGCGTTCACATGCGCTTTCATAcgggacaaaaattaaaatattgcgaaaaatgcaacaaaggCTTTTTGAAACAAGCTCATCTCGAGTGTCACATGAAGAAACATGGTCAGATACGAAAATGCCCGTATTGTCAGGAGGAATTTgacatgataaaattatttagggcTCACATGAACAGCAATCATCCGACGGAAATGGAAAAGGAACGATCTTTTAAGAGGAAACAGCTTCGAAGCACGAAATATGGGCTTGAAACGGAGAAAAAACTCGCccaaaaaagtgttttatTTTTCCCaaaatctaaagaaattttgaagcaTACCGAAATTCATCACGATTTGGAACCCTTTCCCGACCAATGTCAACATTGTCAAAAGCAATTTCCGTGTCAATCGCTACTGGAGCGCCATCTACGACAACAGTGTGAAAACGACTCAAAACGTTTCGTTTGTTCTTCCTGCCCCCAAAAGTTCTTCTGGCCCGATAGTCTTCAGattcatacaaaaatctaccacgaagaagaggaaaaacggaaattttgTTGCGCCATCTGTAGTCGACTTTTTCAGCGGGCGGAACATTTGCAGCGCCATCTGGCGATTCATAATCCAGTGGCGCAAAAATTCGAATGCAACGTCtgtaaaaagttgtttaagcGAAAGGACAATTTGGGAGTTCATATGAAAATTCATGAGCCGAATCGGGAAATTAAGTCGGAATTTTTGTGTACGTTTTGTGGAAAGAGTTTTTCGAATTCGTCGAATTTGATTGTTCATACGAGACGACACACGGGAGATAAGCCGTACAAGTGTGACATGTGTGAAAAGGCTTTTCCGAGAAGTTCGGATCTGCAAACGCATCGGAGGACGCATAcaggtgAAAAGCCCTTCGTTTGTGAAACGTGCGGCAAAGCATTTTCCCGCTCCAACAAACTTTTGCGACACGAAAGAATCCACAAAAATATCCGTCCTTATCAATGTCCTCATTGCGAACGTAGTTTTACCCAAAGTAACGATTTGACGTTACACATTCGACGACACACCGGAGAAAAGCCTTTTCAGTGCGaagtttgtgataaaaaatttattcatggaACTGCTCtaaaaacgcacaaaaaacAACATGAGCAAAATAATCAAGCTGAAAATTCCGAcacaaaaactgtaaaaaagatcaaaaggcTGGTttcggaaaataaaaaatcagttgAAGAAGTAAACCAATCAGAGGGAAAAACAGCCCAAGTACTTCCTTATAATCCGTCAGCGAGTTATGGCGTGACTTTGTTATCGAATGGAACAGTTTTGATGGCTGAAATTCCGCCAAATACAAATGTGTACAAAATTGAGCAATCTTAG
Protein Sequence: MDLKEVTVLNLEKICRICLEVPEEAIHLSTIVYSTFLQEATSYDSQLADLIQMNISTDDILPKQLCNPCAVKLQEFHIFRTKTLKSEEYLRKIVENIETTTENAPENPTKVPYETLDHYDEPFYQNEEYLLNEETSDKKEIDPKTSETNLKDEVSTKRNTIKNSEAKYECPECKKPFVNLKAQRVHMRFHTGQKLKYCEKCNKGFLKQAHLECHMKKHGQIRKCPYCQEEFDMIKLFRAHMNSNHPTEMEKERSFKRKQLRSTKYGLETEKKLAQKSVLFFPKSKEILKHTEIHHDLEPFPDQCQHCQKQFPCQSLLERHLRQQCENDSKRFVCSSCPQKFFWPDSLQIHTKIYHEEEEKRKFCCAICSRLFQRAEHLQRHLAIHNPVAQKFECNVCKKLFKRKDNLGVHMKIHEPNREIKSEFLCTFCGKSFSNSSNLIVHTRRHTGDKPYKCDMCEKAFPRSSDLQTHRRTHTGEKPFVCETCGKAFSRSNKLLRHERIHKNIRPYQCPHCERSFTQSNDLTLHIRRHTGEKPFQCEVCDKKFIHGTALKTHKKQHEQNNQAENSDTKTVKKIKRLVSENKKSVEEVNQSEGKTAQVLPYNPSASYGVTLLSNGTVLMAEIPPNTNVYKIEQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -