Basic Information

Insect: Culicoides brevitarsis
Gene Symbol: ZFX
Assembly: GCA_036172545.2
Location: CM070086.1:12015796-12020424[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 2.8e-05 0.0011 19.1 4.7 2 23 20 41 20 41 0.97

2 13 5.1e-06 0.0002 21.5 1.6 1 23 47 69 47 69 0.98

3 13 1.6e-07 6.3e-06 26.2 1.3 1 23 75 98 75 98 0.98

4 13 0.096 3.7 8.0 2.6 1 23 110 133 110 133 0.95

5 13 9.4e-06 0.00036 20.6 0.3 3 23 222 242 221 242 0.98

6 13 1.8e-05 0.00067 19.8 1.1 1 23 248 270 248 270 0.98

7 13 5e-08 1.9e-06 27.8 2.5 1 23 452 474 452 474 0.99

8 13 0.0013 0.051 13.9 0.7 1 23 480 502 480 502 0.98

9 13 7.9e-05 0.003 17.7 0.3 2 23 510 531 509 531 0.96

10 13 1.4e-06 5.2e-05 23.3 2.3 1 23 537 559 537 559 0.99

11 13 0.00078 0.03 14.6 0.7 2 23 623 646 622 646 0.92

12 13 0.0022 0.085 13.2 0.1 1 23 652 674 652 674 0.97

13 13 0.14 5.4 7.5 3.3 1 14 680 693 680 695 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	2.8e-05	0.0011	19.1	4.7	2	23	20	41	20	41	0.97
2	13	5.1e-06	0.0002	21.5	1.6	1	23	47	69	47	69	0.98
3	13	1.6e-07	6.3e-06	26.2	1.3	1	23	75	98	75	98	0.98
4	13	0.096	3.7	8.0	2.6	1	23	110	133	110	133	0.95
5	13	9.4e-06	0.00036	20.6	0.3	3	23	222	242	221	242	0.98
6	13	1.8e-05	0.00067	19.8	1.1	1	23	248	270	248	270	0.98
7	13	5e-08	1.9e-06	27.8	2.5	1	23	452	474	452	474	0.99
8	13	0.0013	0.051	13.9	0.7	1	23	480	502	480	502	0.98
9	13	7.9e-05	0.003	17.7	0.3	2	23	510	531	509	531	0.96
10	13	1.4e-06	5.2e-05	23.3	2.3	1	23	537	559	537	559	0.99
11	13	0.00078	0.03	14.6	0.7	2	23	623	646	622	646	0.92
12	13	0.0022	0.085	13.2	0.1	1	23	652	674	652	674	0.97
13	13	0.14	5.4	7.5	3.3	1	14	680	693	680	695	0.92

Sequence Information

Coding Sequence: atggaAGAGGAGCCAAGAGATGGAAAAAGCAAAAGTAAAGATGATAAAAGTGATAGAACATGTAGGGATTGTAATAAAGTGTTCAAAACTCGATTTCATCTGAATCGGCATCGATTGATTCACACAGGAGAGAAGCCGTTCGAGTGCGCCAAATGCAACAAAAGATTCATCCAAAAAACCACCTTGAACATTCACATGCTGAAACATCTCGGAAATCGCCCATACCAATGTCGAAAATGCGGTCAACGGTTCTCCCAAAAGGGAAATTTAACTGCTCACATCAAACGTCTTCACAGCAACTTCCTCCGAGAAGGCCAAACTCCAAAATTCAGTTGCAGTCAATGCAcgtgtcaattcaaaaaattagcttCGCTCAACGGACACGTCACACGAGTTCATTCTTTGGTGAAAAAAGTCAAGGAGGACGACGGAGACGAAGTGACGACAGTTCAAAAAGTGTTGGAACAAATAAATGCCTTGAATGACCAACCAAATTTCGTTGTACCTGCTCCGCCGCAAAAACAGCCTTCGGtgacacaagaaaaaattgatgatcgaGTTGTGGTGACAATTCCCGATAATTTTGTCGAAATCACGGATTTTGATGGGAGAAAGTATCGCGTCGAGTATCGTCGAGACGAAAATGGGCGTCGCCTGCTTTTGTGCTACATTTGTGAAAAACCTTTTTATCGACCTTCGGATTTGTTGCGACATCGACGGATTCACACCGATGAACGACCTTTTGTGTGTGAGAAATGTCGAGCGGGGTTCCGAACGAAAAATAGCTTAAAAGCGCATttaaaaactcatgaaaaaaCTCCTCCAGCGACGAAGAATGCCTCGGAAAGGACACAGCCACAACTGAACCAAATCGAAGAAGAGCTGAATTTGCCTCCAACGGAGCCCAGTTTGACTTATAAAGTTGTCGGATACATCTTGGATCAACCAGAACAGCAACAAATAGTGTTCCTTGACTCGCTAGAAAATGCTGAAATCCCGCCGGAAGCATCTCTGATCTATAAACAAGTCGATGATTACATTCCTTCGATGGAAAATTCCGAGCAAGTTTTAATTTGTGACCTTCAAGCGAGTAATTTCATTCAAACGGAGCATTTTCTACCTCAACCGATTGAAGTTTTGACTGAAAATGTGACTCACGAAGTGCCGCAACAACCAAAAGTCTTCACAAATTTGACCCAATTGGCGGAAAATGCGGAAATTCATGTCGAAGGCACAAATTTGACGGTTTGTCAGAAGGAAATTGTCTCCGAACCGCGACTAGAACCTGTAATTaccataaaaaatgttgaaaatgaagcgaaattagatgaaaaaaagagaCCAAGAGCGAATTATACCTGTCAATATTGTTCAAAATCGTTTCGGAGGCCAACGGATCTTCAGCGACATGTTCGCACACACACGAATGAGAAGCCCTATAAATGCACCGAATGTGAAAAAGCCTTTGCATTAAAAGCGACGTTGTTGTTTCATCTAAAAACTCATCAAACAGATCGTGAAAAAGTGTCTTGTCTTATTTGTGATAAGAAATTTACCTCAACGGTAGCGTTGAATGTCCATAAAAGGATTCACAATAATTTGCTTCCTTACAAATGTCAGTATTGCGAGAAACGGGTGAGAAATTCGAGTAATTTAAGGAAACATGAAAGAGTTCATGTTAAAATTGCGGAGAAGACGGGAAAGAGACCTGaagatgttcGTCCTCGTACAACGAAATTTTCTCAACTCCTAAAATACCTTGAAGCATCACAAGTAGTCGAAGGTGTAACGGAAAACAAGAGCAAATCGTATGAAATTGTGATAAGAATGGAATCAGCGAATgacaaaaaggaacaaaagcgGTTTTTATGTCCTTATCAGAACTGTTCGAAGGAATTCTCAAAGCCAAGTTTGTTGGAAAGACACAAATTCGTTCatacaaaagtgaaaaatttcatctgtGATATTTGTGGAAGTAGATTCAATCAAAAAGCCTCAATTGGAGTTCATATGAtatctcaCACGAATTTGTATCAATTTCAATGCAAATATTGTCCACGAAAGTTCAAATTCAAGTCGGGAAGatttGATTCTGTTAAACGTTCTGCGAATAAAAAGCCGGCAATTGTACATGATTTTATTGAGAAACACAAGCAGATTGTCTTTGAGGAACGTTTGAACTAA
Protein Sequence: MEEEPRDGKSKSKDDKSDRTCRDCNKVFKTRFHLNRHRLIHTGEKPFECAKCNKRFIQKTTLNIHMLKHLGNRPYQCRKCGQRFSQKGNLTAHIKRLHSNFLREGQTPKFSCSQCTCQFKKLASLNGHVTRVHSLVKKVKEDDGDEVTTVQKVLEQINALNDQPNFVVPAPPQKQPSVTQEKIDDRVVVTIPDNFVEITDFDGRKYRVEYRRDENGRRLLLCYICEKPFYRPSDLLRHRRIHTDERPFVCEKCRAGFRTKNSLKAHLKTHEKTPPATKNASERTQPQLNQIEEELNLPPTEPSLTYKVVGYILDQPEQQQIVFLDSLENAEIPPEASLIYKQVDDYIPSMENSEQVLICDLQASNFIQTEHFLPQPIEVLTENVTHEVPQQPKVFTNLTQLAENAEIHVEGTNLTVCQKEIVSEPRLEPVITIKNVENEAKLDEKKRPRANYTCQYCSKSFRRPTDLQRHVRTHTNEKPYKCTECEKAFALKATLLFHLKTHQTDREKVSCLICDKKFTSTVALNVHKRIHNNLLPYKCQYCEKRVRNSSNLRKHERVHVKIAEKTGKRPEDVRPRTTKFSQLLKYLEASQVVEGVTENKSKSYEIVIRMESANDKKEQKRFLCPYQNCSKEFSKPSLLERHKFVHTKVKNFICDICGSRFNQKASIGVHMISHTNLYQFQCKYCPRKFKFKSGRFDSVKRSANKKPAIVHDFIEKHKQIVFEERLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -