Cbre007420.1
Basic Information
- Insect
- Culicoides brevitarsis
- Gene Symbol
- -
- Assembly
- GCA_036172545.2
- Location
- CM070086.1:21555170-21558908[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.00049 0.019 15.2 0.4 3 23 242 262 241 262 0.97 2 18 0.00047 0.018 15.3 0.2 1 23 268 291 268 291 0.96 3 18 0.0038 0.15 12.4 1.8 1 23 298 320 298 320 0.98 4 18 8.7e-05 0.0033 17.6 3.7 1 23 326 348 326 348 0.96 5 18 0.00015 0.0058 16.8 5.3 1 23 354 376 354 376 0.98 6 18 0.0016 0.062 13.6 9.5 1 23 382 404 382 404 0.96 7 18 9.2e-06 0.00035 20.7 4.2 1 23 410 432 410 432 0.97 8 18 8.4e-06 0.00032 20.8 3.6 1 23 438 460 438 460 0.97 9 18 1.2e-05 0.00046 20.3 5.4 1 23 466 488 466 488 0.97 10 18 0.0014 0.052 13.8 6.4 1 23 494 516 494 516 0.98 11 18 1.2e-06 4.6e-05 23.4 3.3 1 23 522 544 522 544 0.98 12 18 2.1e-05 0.0008 19.5 5.9 1 23 550 572 550 572 0.98 13 18 4.9e-05 0.0019 18.4 7.1 1 23 578 600 578 600 0.98 14 18 6.7e-07 2.6e-05 24.2 5.6 1 23 606 628 606 628 0.98 15 18 4.7e-05 0.0018 18.4 6.8 1 23 634 657 634 657 0.95 16 18 3.6e-05 0.0014 18.8 0.8 1 23 663 685 663 685 0.98 17 18 0.017 0.65 10.4 3.0 1 23 695 717 695 717 0.98 18 18 0.00029 0.011 16.0 6.6 1 23 723 745 723 746 0.96
Sequence Information
- Coding Sequence
- ATGAATCCCGATATACACATCAAAACTGAAGTTGTAAGTCATGTAAATGGAGAGGAAGGGCTGATGCACCAGAGTATACAATCGGGCCCCAATCAACCCCCTTCAGTTGACAATCCTGACATCCGGTTCAATCCCGTAACATTCCACAATGTCTCGCAACTAGGCAAGTATTTTGTCTTGACAAACCTCTTTCAACAAGGCTCGAACATATATACATCGATACCAAAGctacaaaatatcaaaagtgaCGCCGGTGATGTCATTTTAAATGGTCAAGCTGTCGGTCCATCTGAGTCGAGTTGCACTGTCATTGGAGAAGAGACGCTGCCAATCCACCTACAGCTCGTAGAGTCAAATGTGCATTCCAACAATGAATCTCACAAcacgcaacaacaacaacaacaaataacaaCTCAATCATATTCAGACACTTATTCTGAATCATTGCAAGTCTTGAAACATGATGTAAAGCCGCAAACGAATTCGATTGATGTTCGAAACAGCACTGCAGACAACGACACTAATACAAAACCATTGGAAATGCTTAAAGTCAATATCGatgattttaatcaatttttgaattatcatGAGGTCTTCGGGAAACTGACAACTGATCCTGTTCCTCCCTCTTCGGGTACTTCGGTCACAACTACACAACAACACTTGAGTGACACGCTAGGCACAACAACAGGCTCTGCGATTGGAGCCATATCAGATAATGCGTGTGATTTGTGCGGCAAGTTATTCCAATACAAGTATCAACTTATCGTCCATAGACGATATCACAACGAACGCAAACCATTCACGTGCCAAGTTTGTGGATTAGCTTTTCAAAATTCGGCCGAATTGACGTTACACGGAAAAAGCAAACATGTTGGCGGGTCCAAGATGTACATTTGCAACGTTTGCTTTCACGTTTTTCCCAATGACACATCCCTTGAACGGCATAGCAAGCGCCACTCATCAGATAAACCGTTCCTTTGTAACATTTGCATGAGAACCTTTAATCGTCGTGAGCACTTGGAAAATCATCAGCGGACTCATACAGGAGATTGTCCTTTTCGgtgtagattttgtggaaaaaatttcacaagaaaaGAACATATGGTGAATCACGAACGAAAGCACACAGGAAATACACCACACCATTGCACCcagtgtaataaattttttacgaggAAGGAGCATTTTTCGAATCATATGATGTGGCATTCTGGGCAAACTCCGCACATTTGCACGATTTGCAACAAGAAATATACTCGCAAAGAACATCTAGCAAACCACTTAAGAATTCACACCCACGAAACACCATTCTCCTGCCAAACTTgcggcaaaaattttactcgaaaggAGCACTTTACAAATCACATACTTTGGCACACAGGTGAAACACCACATCGTTGTGACATTTGTTCAAAAACGTTCACCAGAAAGgaacatttattaaatcatGTCAGGCAACATACAGgCGAATCTCCACATAAATgcgatttttgtgaaaagcTTTTTACGCGACGTGAGCATCTTGTAAATCATCGTCGTCAACATACTGGCGAAACACCATTTAGCTGCACGTATTGTCCCAAGGCCTTCTCTCGAAAGGATCATTTGGTCAACCACACCAGGCAACACACGGGAGAAAGTCCATTCAAGTGTGAATATTGTCAAAAACAATTCACTCGTAAGGAACATTTGGTCAATCATAAAAGGCAGCATACAGGCGATTCACCGCATAAATGCCAGTATTGTCAGAAACAGTTTACAAGACGCGAACATTTGAACAATCATGTTCGTTTACACACCGGCGATTCTCCCCATAAATGCGAGACATGCGGAAAAGCTTTTACACGAAAGGAACACTTGACAAATCATATGAAACAACATAATGGAAGTACGGAGCACTGTTGTAATGTTTGTAACAAGCCATTTACTCGAAAAGAACACTTGATAAATCATATGAGTCGATCTCACACTGGCCAGAGACCTTTCAAGTGTGAAGAATGTGGCAAAACATTTCCGTTGAAGGGTAACTTACTTTTCCACCAAAGAAGCCACAATAAAGGGGTGAACGCAGAACGAGCTTTTCGATGTGACTTGTGTCCAAAGGATTTCATTTGTAAAGGTCACTTGGTGTCGCATCGGCGAGCTCATTTTGGAGAACGTCCTTATAATTGCTCCGAATGTACTAAAAAGTTTTGCGAAAGAGGCAACATGATACGACATATGAAAAAACATCATCCGAATATTCCCCTTCCAATCATACCAAAGACCCATCACTCAAATATCATTAAAGTACAAGTTTCTCAACCAAATACATCTAGCATAGAAAGCACTAGTATTAAGTCAGAACCAGTGCCAATGCAACAAACATCCGTTGTTGTGAACGCATCAATTCCTGTTATTACCTCATCAAACAATATTGATAATAATAGTCATAATCAAACAAGTGATTCAATCACGACACACGCGAGTAATGCCATTCAAACAATTCAATACACGCCACACTCACAAATCCATCATCCTCATCAAATTCCATCGATAGAAACAATCAGGACGTCGCACAACTTATTACAACAACACCATATGCCGTCATTGGTAACATCTCCGCCACACTCAATCTCTACCGTTCCCacatcacaacaacaacagcaaataCATGTGATTCGTGGACCAAATGACGTACTAATTTCATCTACTTCCCAAACTATTGGAAGACATGAGCTAACGATTCCTGTTACAATTATCCAAAGTACATCAAATGAACAAGTTGAGCAAGAACAACGATTGCATAGTAATGAGGTTGtctattaa
- Protein Sequence
- MNPDIHIKTEVVSHVNGEEGLMHQSIQSGPNQPPSVDNPDIRFNPVTFHNVSQLGKYFVLTNLFQQGSNIYTSIPKLQNIKSDAGDVILNGQAVGPSESSCTVIGEETLPIHLQLVESNVHSNNESHNTQQQQQQITTQSYSDTYSESLQVLKHDVKPQTNSIDVRNSTADNDTNTKPLEMLKVNIDDFNQFLNYHEVFGKLTTDPVPPSSGTSVTTTQQHLSDTLGTTTGSAIGAISDNACDLCGKLFQYKYQLIVHRRYHNERKPFTCQVCGLAFQNSAELTLHGKSKHVGGSKMYICNVCFHVFPNDTSLERHSKRHSSDKPFLCNICMRTFNRREHLENHQRTHTGDCPFRCRFCGKNFTRKEHMVNHERKHTGNTPHHCTQCNKFFTRKEHFSNHMMWHSGQTPHICTICNKKYTRKEHLANHLRIHTHETPFSCQTCGKNFTRKEHFTNHILWHTGETPHRCDICSKTFTRKEHLLNHVRQHTGESPHKCDFCEKLFTRREHLVNHRRQHTGETPFSCTYCPKAFSRKDHLVNHTRQHTGESPFKCEYCQKQFTRKEHLVNHKRQHTGDSPHKCQYCQKQFTRREHLNNHVRLHTGDSPHKCETCGKAFTRKEHLTNHMKQHNGSTEHCCNVCNKPFTRKEHLINHMSRSHTGQRPFKCEECGKTFPLKGNLLFHQRSHNKGVNAERAFRCDLCPKDFICKGHLVSHRRAHFGERPYNCSECTKKFCERGNMIRHMKKHHPNIPLPIIPKTHHSNIIKVQVSQPNTSSIESTSIKSEPVPMQQTSVVVNASIPVITSSNNIDNNSHNQTSDSITTHASNAIQTIQYTPHSQIHHPHQIPSIETIRTSHNLLQQHHMPSLVTSPPHSISTVPTSQQQQQIHVIRGPNDVLISSTSQTIGRHELTIPVTIIQSTSNEQVEQEQRLHSNEVVY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -