Cbre013676.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culicoides brevitarsis
Gene Symbol
-
Assembly
GCA_036172545.2
Location
CM070087.1:34918792-34922066[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0023 0.087 13.1 6.7 3 23 74 94 73 94 0.96
2 25 0.018 0.68 10.3 4.0 1 23 100 122 100 122 0.93
3 25 0.00043 0.017 15.4 0.1 1 23 128 152 128 152 0.94
4 25 1.8e-05 0.00069 19.7 2.6 1 23 158 180 158 180 0.99
5 25 2.2e-05 0.00085 19.4 1.0 1 23 186 208 186 208 0.97
6 25 0.007 0.27 11.6 1.4 1 23 214 238 214 238 0.96
7 25 4e-08 1.5e-06 28.1 1.0 1 23 244 266 244 266 0.98
8 25 5.6e-06 0.00021 21.3 4.7 1 23 272 294 272 294 0.97
9 25 1.7e-08 6.7e-07 29.2 0.6 1 23 302 324 302 324 0.95
10 25 0.0019 0.074 13.3 5.8 1 23 330 352 330 352 0.98
11 25 0.028 1.1 9.7 0.6 2 23 368 389 368 389 0.89
12 25 0.00027 0.01 16.0 3.7 1 23 395 417 395 417 0.99
13 25 2e-06 7.8e-05 22.7 1.1 2 23 424 445 423 445 0.96
14 25 0.037 1.4 9.3 1.6 1 23 621 643 621 643 0.97
15 25 0.24 9.3 6.7 0.2 2 23 652 673 651 673 0.96
16 25 6.7e-06 0.00025 21.1 4.3 1 23 682 704 682 704 0.98
17 25 4.4e-06 0.00017 21.7 1.3 1 19 710 728 710 732 0.94
18 25 1.3e-06 4.9e-05 23.4 0.3 1 23 738 760 738 760 0.96
19 25 1.8e-05 0.0007 19.7 2.7 1 23 766 788 766 788 0.99
20 25 1e-06 3.9e-05 23.7 1.1 1 23 794 816 794 816 0.98
21 25 4.3e-07 1.7e-05 24.8 0.9 1 23 822 844 822 844 0.98
22 25 9.9e-07 3.8e-05 23.7 2.3 1 23 850 872 850 872 0.98
23 25 5.8e-05 0.0022 18.1 1.5 1 23 878 900 878 900 0.98
24 25 6.7e-06 0.00026 21.1 3.2 1 23 906 928 906 928 0.99
25 25 1.3e-05 0.0005 20.2 0.5 1 23 934 956 934 956 0.98

Sequence Information

Coding Sequence
ATGTTAAAAGGAAATCTCGTGAAGGAAGAAGACGAAACCTTCAAAAATGCAGATTTCAATGCCGTTTATCTCAAACAAAACACGGAAATCGAAGCCGAAACAGTCAAAAAAGAAGATACCGAAGAAGATGCTTTGTCTCCAGATGAAAATGCAAGACCTCACAACACGCGaaacgcgaaaaaaattaaaaagaaagacGAAACAGAGACAGAAAACATTTGTCGTCACTGCAACAAGACCTTCAAGTATCGCAGTCAACTTTTGCATCACGAATTCACGCACAGCTCCGAACGGGCTTACAAATGCGACAAATGTAACAAGCAATTTTTACGCCCAAACGACTTGAAACATCATTCCTACTTGCATCTCGGCTTAAAACCCTTCAAATGTACCGTTGCCGGGTGCGAAAAAGCCTTTGCTCGTTCAGGCGACTTGAAAACGCATTCAGTTGTTCATACGGGGGAACGAAATTACGTTTGTCCCATTtgttcaaagcaattttttcaatcgtCTCATATGAGATCTCATCTCTTGACACATAACAAAGAGAAAACTTTCATTTGTGAGATTTGCAAAAAAGGATTTCATCGTTCAATTAACTTGAAAATTCACATGATGGGTCATTCGGAGGTGCGAAAGTACGTTTGTAATGTCGAAGgatgtcacaaaaaatttgccaAGCCGAGTATTTTACGGAGACATGCTCATATTCACAAAGGAGATAGGGCTTACATGTGTCAAAGTTGCGGAAAAAGCTTCACCCAAGCGGGAAATTTGAAGAAACACATGTTAACTCACACCGGGGAACGACCTCACGAATGCCACGAATGCGGAAGGAAATTTGCACAACGACATCAGCTTCAAGCGCACATGACAATTCACGCAACGGATagtaacaaaacttttttatgccCGGAATGTGGCAAAACTTTTACGCGACAATCGTCTTTGGAGAAACACATGCTTCTGCATACCGATATTCGTCCCTTCGTATGTGAACTTTGTACGAAAACCTTCGTTTGCCAAAGTCACTTAaacaaacatttgaaaaatcatcCAAGCAAGACGCAAATTTTCGCTGAACGAAAACGCCCCGGACGAGAATGTGAAAAATGTGGAATTGTCTTGAGCTCTTTAAGCAACTACAAGGTTCATTGCTTGATCCATACTGGAGTCCAAATTTACCAATGTAACCAATGTGATAAACTCTGTTCGCGCGAAAATGGcttgaaaaaacatttaaaaagtcaCGCGAAGCAAAAAGATTTGTCTTGTCCCATTTGTAAACGAGAATTCAAGCAATCTTTCAACCTGAAACGACATATTCAGCTTCAtagtacaaataaaatttacagtaCAGGTCTTGTGAGTGAAGAAAAAGACACTATCGAAGAGGAAATGATCGTCGAAGAAGTCATTGAACCTCCTCCGGCAGCTGTGATACAAGAAACAATCGTTGTCGTGCCTCCAAGAAGTTCTCCGAACAAGTCTCAAGCATCAACAGTGAAAGAAGAAGCCCTTTTATATGAAGTTGAAGTGCccaaatccaaaaatatcaCATATGATCAAGTCTATCTCGTACAAAATCCCAAAGATGACACCCAAATCGAGTATACTATTGAACAAGATGACACCCATAACTTTTCCTTTGACGAAGAACGGCTAAAAGATGCGACATCGGAAGCCTTTTATACCGCAAATGATATTTTACAAACGGATTTGGACAACGATAACGTTCAAATTGTCTTCGAAGAGTCCCTTTGTCCTGAATTTAGCACGGATTTCATCACAACTGTTGATAATTCGTCGTTTATGGAAACGCAAGAGGCTCTAAAACCTGAAAAAGTTGAGGAACAAAGTCACATTTGCCAGATTTGCAGTCGTCGCTTTATGAGTGCCTTGATTTTGAAGCGTCATTTGATGACTCATCCCGAAGTGAAtcaaattttactgaaatgtCGTTATTGTAAAGACTCGTTTGCGGATGCTGAAGTGTTTAGAATTCATGTCGAGTCGCATCAGGAGTCGGAAATGGATAATTTGtacttttgtgatttttgtggaaaatgttTCGTTCGAAAATCGGATATCAAGAGTCATTTGAGGACGCATTCGACGTTCAAAggtTACAATTGTGATATTTGCGGCAAAAGCTTCACCCATGCCTCATCTTTGCGAAATCACAAACCTCTTCATACGGGACTTCGTAATTACCTCTGTACGCTTTGTGGAAAAAACTTCGCTCGATCTGGCGACTTGAAAAGTCACATGAACATCCATTCAAATGCTAAAAACTATCAATGTTTATCATGTGATAAGCGATTTACGTTGAAATCCACGTTGAGATCTCATCAAATGACCCATACAGGACTTCGACCATACGAATGTAACATTTGCTTGAAGACTTTTACGCAAAGCAGTTCCTTAAAAAGTCACGTTTTGACGCATTCGAATGCCAAAAGTTATCGTTGCAACGAATGTGGGAAGGTTTTCATGACGCCAGCTTACCTGaagaaacatttatttactcaTTCAGGCATTAAACCGTTCTCGTGTGAGACCTGTGGAAAGACTTTTAGTAAACAAGCGCATTTGAGGACTCATCAGATCGTTCAtacaaaggagaaaaattttacttgcgAGATTTGTTTGCATTCTTTTACGTTGGCGAGCAGTTTAAGAAGGCATATGTTGCTTCATGATGGAATTAAGCCATATAAATGCTCGTTATGTGATAAGAATTTCACTCAAGGGGTTCATTTGAAGAAGCATATGTTGAGTCACAGTgGTGTCAAACCATACTCTTGTAATTTGTGTCAAAAGTCATTTTCGGCAGCAGCTACATTGAAAAAGCATCAGTTAGTTCACACGAAACTCGATGACAAATCTCACGAAGATGCGGAAAAGCTTTATTTGACGGTAGTTCATGACGAAACGAACTCGAGCCATTTGCAACAAATACTTCTCTCGCCCGAATTGAAAGTTTGA
Protein Sequence
MLKGNLVKEEDETFKNADFNAVYLKQNTEIEAETVKKEDTEEDALSPDENARPHNTRNAKKIKKKDETETENICRHCNKTFKYRSQLLHHEFTHSSERAYKCDKCNKQFLRPNDLKHHSYLHLGLKPFKCTVAGCEKAFARSGDLKTHSVVHTGERNYVCPICSKQFFQSSHMRSHLLTHNKEKTFICEICKKGFHRSINLKIHMMGHSEVRKYVCNVEGCHKKFAKPSILRRHAHIHKGDRAYMCQSCGKSFTQAGNLKKHMLTHTGERPHECHECGRKFAQRHQLQAHMTIHATDSNKTFLCPECGKTFTRQSSLEKHMLLHTDIRPFVCELCTKTFVCQSHLNKHLKNHPSKTQIFAERKRPGRECEKCGIVLSSLSNYKVHCLIHTGVQIYQCNQCDKLCSRENGLKKHLKSHAKQKDLSCPICKREFKQSFNLKRHIQLHSTNKIYSTGLVSEEKDTIEEEMIVEEVIEPPPAAVIQETIVVVPPRSSPNKSQASTVKEEALLYEVEVPKSKNITYDQVYLVQNPKDDTQIEYTIEQDDTHNFSFDEERLKDATSEAFYTANDILQTDLDNDNVQIVFEESLCPEFSTDFITTVDNSSFMETQEALKPEKVEEQSHICQICSRRFMSALILKRHLMTHPEVNQILLKCRYCKDSFADAEVFRIHVESHQESEMDNLYFCDFCGKCFVRKSDIKSHLRTHSTFKGYNCDICGKSFTHASSLRNHKPLHTGLRNYLCTLCGKNFARSGDLKSHMNIHSNAKNYQCLSCDKRFTLKSTLRSHQMTHTGLRPYECNICLKTFTQSSSLKSHVLTHSNAKSYRCNECGKVFMTPAYLKKHLFTHSGIKPFSCETCGKTFSKQAHLRTHQIVHTKEKNFTCEICLHSFTLASSLRRHMLLHDGIKPYKCSLCDKNFTQGVHLKKHMLSHSGVKPYSCNLCQKSFSAAATLKKHQLVHTKLDDKSHEDAEKLYLTVVHDETNSSHLQQILLSPELKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-