Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: THAP3
Assembly: GCA_015732765.1
Location: NC:224550531-224553317[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2.1 60 4.1 0.5 2 13 140 151 139 153 0.87

2 9 0.35 9.9 6.6 3.1 1 20 428 447 428 448 0.95

3 9 0.011 0.32 11.3 0.6 1 23 459 482 459 482 0.93

4 9 6.1e-07 1.7e-05 24.7 1.9 1 23 521 543 521 543 0.98

5 9 0.0076 0.22 11.8 1.5 1 20 551 570 551 572 0.94

6 9 0.00018 0.0051 16.9 1.5 1 23 610 632 610 632 0.97

7 9 2.2e-05 0.00062 19.8 0.5 1 23 638 660 638 660 0.98

8 9 2.3e-05 0.00066 19.7 0.5 1 23 666 689 666 689 0.96

9 9 0.66 19 5.7 0.1 1 17 695 711 695 712 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2.1	60	4.1	0.5	2	13	140	151	139	153	0.87
2	9	0.35	9.9	6.6	3.1	1	20	428	447	428	448	0.95
3	9	0.011	0.32	11.3	0.6	1	23	459	482	459	482	0.93
4	9	6.1e-07	1.7e-05	24.7	1.9	1	23	521	543	521	543	0.98
5	9	0.0076	0.22	11.8	1.5	1	20	551	570	551	572	0.94
6	9	0.00018	0.0051	16.9	1.5	1	23	610	632	610	632	0.97
7	9	2.2e-05	0.00062	19.8	0.5	1	23	638	660	638	660	0.98
8	9	2.3e-05	0.00066	19.7	0.5	1	23	666	689	666	689	0.96
9	9	0.66	19	5.7	0.1	1	17	695	711	695	712	0.85

Sequence Information

Coding Sequence: ATGCCGTCGTCGTGTTCCGTGCCAGATTGCGAACTAAAGTACGCCCATTCGGAAGACGTTTCGTACCATAAATTCCCTCTGAAGAAACCGGAACTACTAAGCGAGTGGGTCAAATTTACCGGACGTGACCCAGCCTGGGTTCCGAGCCGTTGGAGTGCCATCTGCAGTCGGCACTTCAAGCCGTCCGATTTCAAGGATTGCATTTACAGgAAAAATCTGACCATCAACGCCGTTCCTTCCGTTCGAGTGAGACATCACACACCAATTTCGGAATTTATTGCCGGAAAGTGCGATGTCGACGAAGAACCTAAAACTCCTCACGAGGAAACGTTGCACGATACCCATTCGGATCAACCGGATGCGGAGACGGATCAGGATGATTATTCCGGTGGAGAGGAGACAAATCTGCTGGACATTACGTGTCGGCTGTGTGGAATCGTGTTTAGCAAGTGGTGTCAGGGATTGCTGGTGGATTTCCGGCCGCATTCCGTGGTCATTGGAAAGTGTTTGCCGTTCGTCAATTTGGAGCTGGTTCATTTTCCTGCGAAGGTTTGTGGCCACTGCCTGAAGGTCATCAACGGATTTTCTGCGTTTTATGACAGCGTTCAACGGGCTCAGGTTGATTTAGAGCTAAAGTACAACAATCGAGTGGATGAGCATGATCCGGTAGATGAGCATATTCTTGAAGCGCCCAAGATTCGAATCAAGCAGGAACCGATGGTCAACATCAAGGAGGAGGCAATCGAATCAAACATTCGAATCCGGGAGAATCCACTTCCGGAAACTCCGGAAAATACTCTCATAATCAAAAATCCAAACGTTGCCAGTGATAACAACAAAATTCTGGTGTTTAAAAATCAGAGTACTGAAAATCAGAACACGAAGCCAATGCCCAAAAACTGTGAAATTTTGGAGATCGTCAACCTCTACCCTCCAATTGTGGACATCACGAGCGCTACCATTCGGGAAGTTCAACCCTACGAAATCACCCTTCCTTCAATTTCAAATGCTCCATCGTTTCAATCAGCACCTCCCCAAATCATCAACCTTAAAACGGAAAACACAGCAGAGTTCGAAGAAGAATACGAAGACTACTCCGGATATTACGACTTTCAGCTGGCACTGAACACGCTAGATGAGCACAGCTATTCCAAGCTCCCAATCCAAGCAGACGACAACAAGGACGAAATCTTCCCCCATCTTCCGGAACCAATGGATCCCATTCAGCTGGGAGAATCCGGGACGGTTCAAGTCATCCACGTAGAACTTCCAGCGGTAACCTTCTCGTGCAAATCCTGCCATCATATCTTCCCAACCCGACTGAAGCTGCTTCGCCACCGAACCTTCTACTGTCCGTCGCGGAAGCGACCTCACTTCCGGTGCGTCTACTGTGCGAAAAAGTTCCCCATCCGAACCCAACTCCAAATCCATCTGGCCGCCTGCCATCGAAGGACCGCCCGGCGGAAGCATCTGGCCTCCAAGGCGAGTGCCGTCAAAAACGCTGTCCGACAGGCAACCACCAATCAAGCCGAACCGCAATCGACGACCCACCCCAAAACCTACACCTGTGATATGTGCGACCGGACGTACTCGCGGATGTCGAACCTGCGCCGGCACCAGCTCAGCCATCGACCGATGGAGCAGTGGAACCACAAGTGTGGCGTCTGCCAGAAGATCTTCGATAAGCTGTTCGACCTGAAGAAGCACTTTCAGCTGAGCAAGTGCGCTGGCAGTAGTGGCGGGGATGGCGGGTACGTGCTTCCGGTGAGGAGTGGTGAGGAAACGGGGTCGGTTCCGGCGCCGGAAGGCGCACTGGATCGACTGCTGTACGTTTGTTCGACGTGCAATAAGCAGTTCAAGAGTTATAACAGCTTAAAGGTGCACGAAAGTATCCACACGGGACTGAAGGCGTACATCTGCGAGACCTGTGGGAAGCGGTTCGGAGGGCAGATGAACCTGACCCAGCATCGGTTGACGCACACGGAGCTGAGGCAGTTTGCGTGCAAGTTGTGCCCGAAGgttttcaaacggagcGGTGGTCTGAGCCAGCATGTCAAATCGTTCCACATGAAAATCAAGCCGTACCAGTGTCCGGTTTGTTTCCGGGATTTTGCGCTCAAGGCTGATATGACCCGGTGTCGTCACTCGAAGCTGAAGGAGAATGGATAA
Protein Sequence: MPSSCSVPDCELKYAHSEDVSYHKFPLKKPELLSEWVKFTGRDPAWVPSRWSAICSRHFKPSDFKDCIYRKNLTINAVPSVRVRHHTPISEFIAGKCDVDEEPKTPHEETLHDTHSDQPDAETDQDDYSGGEETNLLDITCRLCGIVFSKWCQGLLVDFRPHSVVIGKCLPFVNLELVHFPAKVCGHCLKVINGFSAFYDSVQRAQVDLELKYNNRVDEHDPVDEHILEAPKIRIKQEPMVNIKEEAIESNIRIRENPLPETPENTLIIKNPNVASDNNKILVFKNQSTENQNTKPMPKNCEILEIVNLYPPIVDITSATIREVQPYEITLPSISNAPSFQSAPPQIINLKTENTAEFEEEYEDYSGYYDFQLALNTLDEHSYSKLPIQADDNKDEIFPHLPEPMDPIQLGESGTVQVIHVELPAVTFSCKSCHHIFPTRLKLLRHRTFYCPSRKRPHFRCVYCAKKFPIRTQLQIHLAACHRRTARRKHLASKASAVKNAVRQATTNQAEPQSTTHPKTYTCDMCDRTYSRMSNLRRHQLSHRPMEQWNHKCGVCQKIFDKLFDLKKHFQLSKCAGSSGGDGGYVLPVRSGEETGSVPAPEGALDRLLYVCSTCNKQFKSYNSLKVHESIHTGLKAYICETCGKRFGGQMNLTQHRLTHTELRQFACKLCPKVFKRSGGLSQHVKSFHMKIKPYQCPVCFRDFALKADMTRCRHSKLKENG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401046; iTF_00401758;
90% Identity: iTF_00401046; iTF_00401758;
80% Identity: iTF_00401758;