Basic Information

Gene Symbol
-
Assembly
GCA_015732765.1
Location
NC:147470225-147625454[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.087 2.5 8.5 0.2 3 21 15 33 13 34 0.92
2 14 0.7 20 5.6 0.6 3 23 303 325 301 325 0.91
3 14 0.26 7.3 7.0 0.8 2 20 518 536 517 537 0.94
4 14 0.051 1.5 9.2 1.8 1 23 558 581 558 581 0.95
5 14 0.047 1.4 9.3 0.3 1 23 586 610 586 610 0.90
6 14 0.48 14 6.2 2.6 2 23 627 649 626 649 0.96
7 14 0.0025 0.072 13.3 0.0 1 21 654 674 654 675 0.96
8 14 0.18 5.1 7.5 0.2 2 23 926 947 925 947 0.92
9 14 0.0019 0.055 13.7 0.3 2 23 960 980 959 980 0.96
10 14 2.4e-05 0.00069 19.7 0.2 1 23 986 1009 986 1009 0.92
11 14 2.1e-05 0.0006 19.9 0.2 1 23 1031 1053 1031 1053 0.98
12 14 0.024 0.67 10.3 0.4 1 23 1093 1117 1093 1117 0.93
13 14 0.0079 0.22 11.8 0.8 1 23 1124 1148 1124 1148 0.98
14 14 0.00096 0.027 14.6 2.8 1 21 1154 1174 1154 1179 0.93

Sequence Information

Coding Sequence
ATGATGCTGCACGAGGAGGTCGAGCTGGACGATACCCACCTTTGCAACAAATGTGGCCGTACCGTGGTGGGGTTGGAGAATTACATCAAGCACAGGAAGGCGAACTGTGTCCAGTCGAAACCGGCAACGGTAATTGCCGGTGGATCTAGTTCGCGGATTGGTTCCGTACATGGTTACGGGTCGTTCGATTTCGGTGAAGGTATTAAGGACACGGATCATCACAAGAAGCTTCCGAACTACAGTTTTAACTATGACTTGGAAGCGCCTCACGCTGATCCGGTGCAGCGACCGGACAGTAAGACCGAGTACAAAAATGAGGTTAATTATGACTACGAATTGGGAGCGGATCTGTTCTTTTCGTCTCTGGAACTGCAAAGTAGCTCGAAAAAGAATCTCAACACATCGGCCTCGAAGATAAGCGTTCCGAGCCGTCCAAAGTCTCGGAAGCCAACAAGCTCGCTGTCCACCACCGATCCCGATCAGGAGCATGAACAAGAAGACGACTGGATCGATCCACACCACGATTCGGACAAGCTCATGAAGGCCGTTAGTGACATCAGTGGTAACAAGCGAGAGGACTCCATCTACACATTCTTCCACCACGAATCGCCGGAACCGTCGGACGAGGAAAGTGATGAAGAGGAAGACTTTGACGCTCCACCGAGGACTCACACCGGTGGTAAGTGGAAGCCGGAGAATCGCCCATCGTCGTCCCAGTGGCGTCACTGGCCGGACCAAGAAGGACAGCTGGATAAATCCATTGAGCACGAGGAAGAGGAGGAGTACAAAAGCTTCTCGCCGCCTCCCGGACACACCAAGGGTAAGTGGGTGCCCGGATCGAAGATTACCCGGTTGGAGTACAAAACTCCTACGGTTCCGAGCAAGAGTTTTGACACGACCTATTGGTGTAGTATCTGTAACAGAAAGCTAGCTTCGAGATTTGTGTACGAACGGCACCTCAAGTCGAATCTTCACATCAAGCGAGCTCAGGAAGAGTCCGAGCTAGAACGTGCCGTCAAGCCGACGCAGTATCCAAACGAGCTGTCGAAGCGCGTTGTCAAGCCTTCCGTCTACCTTGGAGATGATTTCCTCACGACCAGTTTGGCCCCGGAACAGACGTCGACACCAACGAAGCTCAAGCGGAAGCGCAAGTGTTACTACACTAAGTGCGAAATCTGCAAGACACGGCTTCCGACTCACCTTCTCGGGAAGCATCTGATCTCACGATACCACTACCGACGAATGCTGAATCATCCGGGACAGTGCTTTGACGTCATCCTGAAGAACGTTCACCGGATCGTGTTGCAATCTCCGTTCCAGTGTCATCCCTGCAAGTTTTACGCGAACAACCAAGAGCAGTTCATGACCCACTGGAACTCACTTGGTCACGAACAGCAGGTCAGCTCCAGTGGCAAGTTTTGGTGCAGCTTCTGCAAGTTCGAGTGCATTGAGAACTTTCAAATGACCAACCACCTGTTAGCGGACCATCAAGAGGTCATTTCCGTTATCAACCGATCCGTCCCGATCATCATCCGTAAAATCACCCCAATAACCTGCTTCTTCTGTGGCGATGAGTTCCGCTACAACGTCCAACTCCAGAAACACCACGAGTTCTGCAACGAGGGAACCCCCGAAGATACCAACCGGGTCAAGCGGTCCTTTCAAAACGCCTTCTCCTGCGACCTCTGCAAGGCTTCCTTCCACAATAAGATGCTTCTCCTCCAGCACGGTCAAAAGCTGCACCGTCTTACGACCTACTACTGCTCGATCTGCGAACTATCCTTCAATACCCCGGCCGAATCCAAACTACACCGCCAAACCACGGCCCACAAAGTAATGTCCGCGCGCAAACGCAAAACGCTCAACCCATCCGGCAAACGCTGCCACATCTGCAAGCAATACCTCGCCGACATCCTTGAGCTCAAACATCACATCCGGCAGGACCATCCCGAAGTCAAGTACAGCTGCCCCCAGTGCGGTCAAAGTTTCGTGCTAGCCCAAGAACTTGGCAGACACGTACgtgacaaaaattgtacatttttCAATTCGCCAGCACTGCAGCAGCCGGAGACGGAGCCGCTGCCGTTATCATCAACCGCCGCTGCCGGAAAAGCAGTCCCATCAACAGCCCGGGCGCATCTTCCGGGCGAAAATTCAATTATCCTAAATGATTCAATTAAAGTAAATATGAATGATCATAAAATAGGAAAGGAGTCACATCTGTATTCTTCGGCTCCGGTCACGGGCACGATGATGGTGCGGCGGACGGTCCTGGTCGGCGGCCGGACGGAAACCGTTTCGAGAGCACCGACGTTGGTGGAGGCGGTGgaggctggcaacactgctgatGAGTCGTCCGGAGCTCTGTCAACCATGCCGGCAATGACCATGATGGACCATTACACCAACCTTCTGCCGACCATCCCATCTGAACCATCAGAACCAACAACAACTTTGGTGCTATCAACCACAGTCGCAACGGTAGCAGAGAAGCCAGAATCGACACCCGAAATTGAGACCCATCACttggctggcaacactgtcaccaccaccaccaccaccatcacaaCCTTCGACCCAGCATCGTCCTCGACCATGATAACCTCGGCATCAAATTCCACTTGTGATGATAATATTGTCACCACCAGTGTTGGGGCCGTGTCCACGTCAGCAGAAATCTTTTTCGCCATGGCTAATAATGCGTCCGAAAATAATACTGTTTACGTTGATGAAATTGTTGGCACCATCACGGACGACGGCTCCGACATTTCCTGGCAGTGTAAAATATGCCCATTCAgGACCTCATCACAAGCGGAATTTTTGTACCATGGTATTCTGCACTCGTCAAAGGTCGACACGGCCAGTACGGCCAAGATTCCCTGCTCCCTCTGTCGGAAACCCTTTCGGAGGGCCTCCCTCAGGGCACACCTGCGCCAGCACACCAACGAACGGATCTTTCCCTGTGAGCTCTGTCCAATGAGCTTTACGCGGAAGGCGAATCTTAAGAACCACGTGGACAACATTCACGCCGCTGTGAGGTTGGAGTCGGAGATGACCATCGACGATGTGCCCGTGATTGAGCGGAAGTTTTTCGTCTGTGAAACGTGCGGCAAGGCGTTCGGTAACAGCAACCTGCTTCTTCAGCATACCCGCGTCCACCTGAGGGACAGATCGATCAAGGAATTTGCCTGTCAGCACGCCGGCTGCTTCTACGTGGGCCGAAGCGCGGCCGAGGTGCGAACCCATCTGGCCAGCCGCCACTCGGACGAGCGGAACTTTGTCTGCGTCGAGCCAGACTGCGACTACCGGGGGAAAACCATCACTCAGCTGCGACGACACTATCAGCGCCATGGAGACTCCGAGAAAAAGTACAAGTGTAATTTCGCCAGTTGTGACTTTGCGACGCGCGTTCCCGGACATTTGAAAAGACATCTTTTGGTGCACAGCGGAACCAAACCGTACTCCTGCCCACATTGTGATTACAGCTGCAACAACATTGAAAATCTCCGCAAACACGTGATTTCGACATCCAAGCATAAAGGAAAGTATTTGTACGAGTGCAAATTCTGCTCGTTGCACGATGAACAGGGCTCGAACGTGTTCAAATCGAACTTTAGCAAAGACTACAAAGATCATTTGATGGGAGTGCATAAATTCACCTCGGAAAAGGCAACCCAGGTGGCGCGAATTTAA
Protein Sequence
MMLHEEVELDDTHLCNKCGRTVVGLENYIKHRKANCVQSKPATVIAGGSSSRIGSVHGYGSFDFGEGIKDTDHHKKLPNYSFNYDLEAPHADPVQRPDSKTEYKNEVNYDYELGADLFFSSLELQSSSKKNLNTSASKISVPSRPKSRKPTSSLSTTDPDQEHEQEDDWIDPHHDSDKLMKAVSDISGNKREDSIYTFFHHESPEPSDEESDEEEDFDAPPRTHTGGKWKPENRPSSSQWRHWPDQEGQLDKSIEHEEEEEYKSFSPPPGHTKGKWVPGSKITRLEYKTPTVPSKSFDTTYWCSICNRKLASRFVYERHLKSNLHIKRAQEESELERAVKPTQYPNELSKRVVKPSVYLGDDFLTTSLAPEQTSTPTKLKRKRKCYYTKCEICKTRLPTHLLGKHLISRYHYRRMLNHPGQCFDVILKNVHRIVLQSPFQCHPCKFYANNQEQFMTHWNSLGHEQQVSSSGKFWCSFCKFECIENFQMTNHLLADHQEVISVINRSVPIIIRKITPITCFFCGDEFRYNVQLQKHHEFCNEGTPEDTNRVKRSFQNAFSCDLCKASFHNKMLLLQHGQKLHRLTTYYCSICELSFNTPAESKLHRQTTAHKVMSARKRKTLNPSGKRCHICKQYLADILELKHHIRQDHPEVKYSCPQCGQSFVLAQELGRHVRDKNCTFFNSPALQQPETEPLPLSSTAAAGKAVPSTARAHLPGENSIILNDSIKVNMNDHKIGKESHLYSSAPVTGTMMVRRTVLVGGRTETVSRAPTLVEAVEAGNTADESSGALSTMPAMTMMDHYTNLLPTIPSEPSEPTTTLVLSTTVATVAEKPESTPEIETHHLAGNTVTTTTTTITTFDPASSSTMITSASNSTCDDNIVTTSVGAVSTSAEIFFAMANNASENNTVYVDEIVGTITDDGSDISWQCKICPFRTSSQAEFLYHGILHSSKVDTASTAKIPCSLCRKPFRRASLRAHLRQHTNERIFPCELCPMSFTRKANLKNHVDNIHAAVRLESEMTIDDVPVIERKFFVCETCGKAFGNSNLLLQHTRVHLRDRSIKEFACQHAGCFYVGRSAAEVRTHLASRHSDERNFVCVEPDCDYRGKTITQLRRHYQRHGDSEKKYKCNFASCDFATRVPGHLKRHLLVHSGTKPYSCPHCDYSCNNIENLRKHVISTSKHKGKYLYECKFCSLHDEQGSNVFKSNFSKDYKDHLMGVHKFTSEKATQVARI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00401144;
90% Identity
iTF_00401144;
80% Identity
-