Cqui014014.1
Basic Information
- Insect
- Culex quinquefasciatus
- Gene Symbol
- -
- Assembly
- GCA_015732765.1
- Location
- NC:175042137-175043583[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.026 0.73 10.2 3.2 3 23 137 158 137 158 0.97 2 10 2 56 4.2 1.0 6 23 167 184 167 184 0.98 3 10 0.0046 0.13 12.5 3.2 1 23 190 213 190 213 0.93 4 10 6.8e-06 0.00019 21.4 0.7 1 23 220 242 220 242 0.99 5 10 0.00035 0.0099 16.0 0.1 2 23 246 268 245 268 0.94 6 10 0.0012 0.034 14.3 1.3 1 23 274 296 274 296 0.96 7 10 0.00054 0.015 15.4 0.7 2 23 306 328 305 328 0.97 8 10 0.0034 0.097 12.9 0.6 3 23 337 358 336 358 0.97 9 10 8.5e-06 0.00024 21.1 1.6 1 23 363 385 363 385 0.97 10 10 0.00036 0.01 16.0 1.2 1 23 391 414 391 414 0.96
Sequence Information
- Coding Sequence
- ATGTCCCAGATCCAGGAAATGTGCCGAATCTGTCTCAATCTCAAGCTGGAACCGGATGACACCGCCGCGATAACGGACGACAAGTTTCAAGCAAAGATTCAAGCAGTTTTTAGCTTTGAGCTTCCAACCGATGATCCACTGCCCTGCCGGATGTGCCGAGCCTGTTGCGTCAAAATTGACGAGTTTTACGCGTTTCACGAGGCGGTCCGGTCCAGCCAGGTTCAGCTGCAGCTGATGCTGAGTAGTGGAGCTGGCGAGGAGGTTGTCAAGCAGGAGCAGGCCGATTCCGACCTCGAGGAGGCAAAGATGACAGGCCACTTAACGGCAGGCAGGGTAAGGTTGGGAAGGGGAGAAAAGCAAAAGTTGGAGGATGAGAACAAGCAGATTAAGGAGTTTTTCAAGCTGGGTTGTGAATCATGTTCGGAGTGTTTCGAATCGTTTGACCGATTGCAGCGGCATACCCGGAAGGCGCACGATGCTCGGGCGAGTATCAAGTGCTGCAATCGAGTGTTTTATAAAAAGTGCAAGATATTGGAGCATATTAATTCGCACATCGATCCGAACCAGTTCCATTGCGATGTTTGCAACAAGAGTTACAATAGCAAATATTATTTGGATCTGCACAACTTGAAGATGCACTCCGACGAGGCGCTTCCGTTCAAATGTGAGAAATGCGGCCGCGGTTTTCCGAAAGAGTATCTGCTGAAGAGTCATTTGGAGACGCACGTGCAGGTTGTTTGCTCGGTATGTAACAAAACGCTGGCTAGTTCGGCAACGTTGCGAAGTCACATGGCCAACATGCACAACGGCGGGACGAAGCATATCTGCGACACCTGTGGCCAGGAATTTCGGACGAAACTCGCGATGGATCGGCACATTAAGCAGCATCTGGGGATCAATCCGATCGAGCGGGTTCAGTGCCACATCTGCAGCAAGTGGGTCAACGGGAAATCTAACTTGAAGATCCACATTCGGACGGTTCACAACGAGGACAACCAGTCGGTAGCTTGCGAGGTTTGCCATCAGATGTATCCGAACGAACGGGCCCTCAGCAGCCACCGGCGGCGTGTCCACGTGGAGGAGAAGTTCGAGTGTGAGTTCTGCGGTAAGAAGTTCAAGCGAAGCATTTATTTGAAGGAACACCGAGCTTCCCACACCGGACAAGCGCTTTACTCCTGTAACGTTTGCGGCATGACCACGAACTCGAACGCGAACCTCTACTCTCACAAGAAGAACAAACACCCGGAACAGTGGCTGGAGGCCAAGAAGAAAGCCATGACCGCGGCTTACGGATGA
- Protein Sequence
- MSQIQEMCRICLNLKLEPDDTAAITDDKFQAKIQAVFSFELPTDDPLPCRMCRACCVKIDEFYAFHEAVRSSQVQLQLMLSSGAGEEVVKQEQADSDLEEAKMTGHLTAGRVRLGRGEKQKLEDENKQIKEFFKLGCESCSECFESFDRLQRHTRKAHDARASIKCCNRVFYKKCKILEHINSHIDPNQFHCDVCNKSYNSKYYLDLHNLKMHSDEALPFKCEKCGRGFPKEYLLKSHLETHVQVVCSVCNKTLASSATLRSHMANMHNGGTKHICDTCGQEFRTKLAMDRHIKQHLGINPIERVQCHICSKWVNGKSNLKIHIRTVHNEDNQSVACEVCHQMYPNERALSSHRRRVHVEEKFECEFCGKKFKRSIYLKEHRASHTGQALYSCNVCGMTTNSNANLYSHKKNKHPEQWLEAKKKAMTAAYG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00401004;
- 90% Identity
- iTF_00401004;
- 80% Identity
- -