Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:51430336-51431768[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.5 72 3.9 0.1 1 16 58 73 58 75 0.79

2 7 1.4 39 4.7 0.1 3 23 202 219 200 219 0.73

3 7 3.8e-06 0.00011 22.2 1.1 1 23 225 247 225 247 0.98

4 7 1.6e-05 0.00047 20.2 0.5 1 23 253 275 253 275 0.99

5 7 5.7e-06 0.00016 21.7 0.5 1 23 281 303 281 303 0.99

6 7 0.00032 0.0091 16.2 0.1 2 23 310 331 309 331 0.94

7 7 1.4e-05 0.0004 20.4 0.8 1 23 337 360 337 360 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.5	72	3.9	0.1	1	16	58	73	58	75	0.79
2	7	1.4	39	4.7	0.1	3	23	202	219	200	219	0.73
3	7	3.8e-06	0.00011	22.2	1.1	1	23	225	247	225	247	0.98
4	7	1.6e-05	0.00047	20.2	0.5	1	23	253	275	253	275	0.99
5	7	5.7e-06	0.00016	21.7	0.5	1	23	281	303	281	303	0.99
6	7	0.00032	0.0091	16.2	0.1	2	23	310	331	309	331	0.94
7	7	1.4e-05	0.0004	20.4	0.8	1	23	337	360	337	360	0.97

Sequence Information

Coding Sequence: ATGACTTCGATTTGCTGTCGGCTGTGCCTACTCGACGGACCCGATCTCCGGCCGCTTCTGGGTCTTACGGTCGATTCAAATGGATTCGGCGAACCGGTCACATCGGCCCTGTCCCAACTTATCGCTTGTTACTTGGCGATTGAGCCTCTTATCGCAAGTCCAGCCACGACCTACATCTGCTCCGACTGCGGGAACACGATCGCCAAGTGGCACTGGTTCCGGGAGTCATGTCTCCAGAATGATGGCGTCTACCGGAAGATGGTTCCAGAGCAGATTGGCGAATACCAAGTTGTTGAGGTCAAGCAGGAGATCGACATCGGCGAGCATGAGTACAGCGACAGCCTGATCACGGAACCGCTGGCTTCGTCTTCTAAAGAGAGCCAGGGTTGTCCCGAAAAGGGGATCACTGAGGAGAGCTCTCCAGCTAAGGCGGATCAATGCCACGATGTTGTGGTGAAACAAGAGCAGAAGGATGAGGTTGGCGAGCAAGACTACAGCGAAAACTTGCCCACCGAACCGCTCGATCTTGCTCCGAAGCCGGTGAAGAAAAAGATGGGACGGCCTCGACTTACGGAGGCACAAAGGAATCAAAAGGGACAAATGTGCGCGCAGTGTGGGAAAGTGGTGAATAACCTGTCCGCTCATTTGACAATGCACAACCAGGATAGGTGCTTCCAGTGTCCACATTGCCCGATGAGTTTCTACAGCAAAGCCAACTGGAAAACTCACGTCAACGTGCACACAAAGGAAATCAAATACACCTGCCCGGTGTGCGATAGAATTTTCTGGCGAAACAACACTCTCCAGACGCACATGCAAAGTCACTCGACAGATCAGGCCTACAAATGTCCGCACTGTCCGAAAGTGTACCGGTTGCGAGCCGGGCTGGCAGTCCACCAGAAGAGTCACACCCAGGAGCCGGATGTGCCGTGTGACGGATGCGACAGAAAGTTTTATTCAAAGGCTCAACTGGACAAACACGCCGTCATGCACCGACCGGTTAAACGAttcgtttgtaaaatttgcGAACAAGGATTTACCAAAAAGCCCTACCTAATGAGGCACATGGAGAAAAATCACCCGGATTGCATAGAAATGGAGGAGAAGCCCAATATTGGAGCTGAACTCGGAAGTTTGTGA
Protein Sequence: MTSICCRLCLLDGPDLRPLLGLTVDSNGFGEPVTSALSQLIACYLAIEPLIASPATTYICSDCGNTIAKWHWFRESCLQNDGVYRKMVPEQIGEYQVVEVKQEIDIGEHEYSDSLITEPLASSSKESQGCPEKGITEESSPAKADQCHDVVVKQEQKDEVGEQDYSENLPTEPLDLAPKPVKKKMGRPRLTEAQRNQKGQMCAQCGKVVNNLSAHLTMHNQDRCFQCPHCPMSFYSKANWKTHVNVHTKEIKYTCPVCDRIFWRNNTLQTHMQSHSTDQAYKCPHCPKVYRLRAGLAVHQKSHTQEPDVPCDGCDRKFYSKAQLDKHAVMHRPVKRFVCKICEQGFTKKPYLMRHMEKNHPDCIEMEEKPNIGAELGSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400996;
90% Identity: iTF_00400996;
80% Identity: -