Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:189549676-189555716[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00011 0.0032 17.6 0.8 1 23 163 185 163 185 0.95

2 15 0.82 23 5.4 3.4 1 23 191 213 191 213 0.96

3 15 3.9e-05 0.0011 19.0 0.2 1 23 331 353 331 353 0.98

4 15 0.011 0.31 11.3 0.3 1 23 359 382 359 382 0.97

5 15 0.00014 0.0039 17.3 0.6 3 23 433 454 432 454 0.96

6 15 0.031 0.89 9.9 0.0 2 23 513 534 512 534 0.94

7 15 2 57 4.2 1.6 1 23 540 563 540 563 0.79

8 15 1.2 34 4.9 1.3 2 19 571 588 570 589 0.94

9 15 0.0018 0.051 13.8 8.4 1 23 602 624 602 624 0.95

10 15 0.049 1.4 9.3 0.5 2 23 630 651 629 651 0.97

11 15 1e-05 0.00029 20.9 1.3 1 23 657 679 657 679 0.98

12 15 0.0086 0.24 11.7 0.2 3 23 687 707 685 707 0.97

13 15 0.00063 0.018 15.2 0.5 3 23 715 735 713 736 0.95

14 15 0.02 0.57 10.5 0.1 1 23 750 772 750 772 0.97

15 15 0.0053 0.15 12.3 0.0 1 20 1224 1243 1224 1246 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00011	0.0032	17.6	0.8	1	23	163	185	163	185	0.95
2	15	0.82	23	5.4	3.4	1	23	191	213	191	213	0.96
3	15	3.9e-05	0.0011	19.0	0.2	1	23	331	353	331	353	0.98
4	15	0.011	0.31	11.3	0.3	1	23	359	382	359	382	0.97
5	15	0.00014	0.0039	17.3	0.6	3	23	433	454	432	454	0.96
6	15	0.031	0.89	9.9	0.0	2	23	513	534	512	534	0.94
7	15	2	57	4.2	1.6	1	23	540	563	540	563	0.79
8	15	1.2	34	4.9	1.3	2	19	571	588	570	589	0.94
9	15	0.0018	0.051	13.8	8.4	1	23	602	624	602	624	0.95
10	15	0.049	1.4	9.3	0.5	2	23	630	651	629	651	0.97
11	15	1e-05	0.00029	20.9	1.3	1	23	657	679	657	679	0.98
12	15	0.0086	0.24	11.7	0.2	3	23	687	707	685	707	0.97
13	15	0.00063	0.018	15.2	0.5	3	23	715	735	713	736	0.95
14	15	0.02	0.57	10.5	0.1	1	23	750	772	750	772	0.97
15	15	0.0053	0.15	12.3	0.0	1	20	1224	1243	1224	1246	0.93

Sequence Information

Coding Sequence: ATGGACCACACGACGTTCACGATATGGGATCCAACGCAGCCGAACGCCAAGATGAAGATCATCAACATTGCCGGCGAGGCGTCTCAATCTCAGTACATAGAAACTGTCACCACGGCCTCAGCCCAAACCGAACAGATCATTCTGCAGACGCACGACGGCCGGGGCTTTCTGATGAACGAAAACGAAATCAGTCGGATCGATCAGATCCCACCCGAAAACCTGATCTACATGGCCGCCGACGACGGGTCGCTCATCCAGGGCGAGGTGGTCCACGTCCAGCCGGAGGAACAGCACCAAACGACCGAAGAGTACATGGAGTGTGAGGTCACCGAGGAGGTCATCACGGACGACTGGGTGCAAACAGATGGCCAGGAGTGCGTCCAGGTAACGGTCGATCAGCTGGGAGCGACGGCCGTTGTAGGAGCAGAGGACGACATGACGGTTCCGCTGCCCACCGACCAGGACGAATACACGGCTTCGCGACCCTATCCGTGCGATTTCTGCAGCCGACGGTTTCGCAAAAAGGTCAACCTAATGAACCACATGGTGGCCCACTCGAACGATCGGCCGCACATGTGCAACCTGTGCGGAGCCCGCTACTTGCGACGCTGTGACCTGCTCAACCACCTGAAGCTGCACGCGTACGTTCCCGACGACAGCGAGGAACCGATTCGGAGCGATCCGGAGGACGATTACCAGTACGACATGGTGGAACAGCAACCTGGGCCCATCAAGAGGCGGTCGCCTTCCGTGGACGACGAGCCGGGAAGCCTCCTGATTCCGGCACCAGCCCCGTACAAACCACCCAAACCGGCTCGCGCCAAAGCACGACCGAAAGCTTCCCAAAGCAAATCCCACAAGAAATCATCTACCTCTTCAGCGGCCCGTGCTCGCCAGGCTCCACCCCAAACGGAGTCCAAGTTCAACGCGTCAATCGAACCGTTCGTCAACCTTCCGCCCCGGTACCCGGTGATGGACGATCGCAAGCCATTCGTGTGTCAAAAGTGTGGAGTTTCGTTTGCGCGCGAAAAAGCTCTAGCGTCCCACTACCGAATACACGGCGGCGATTCTCAGTACGAGTGTGAAACGTGCGGCGATCGGTTCTGGGATCGTTCACTGCTGCAGGATCACATCCGGCAACGTCATGCGGCCTCGTTGGTGGCAGTTGAACCACCTACGCTGGACAATAGTGTCGTCGGTGGTGGCGGTACAACGATAGTGGAGGAAGTGGCCGCGGATGTTCACGAGGGAGAATTAGTTCAGGAGTCAACGGACGATGGCAAGTGGCACCCGTTTTGTGACAGCTGTGGGATGGTGTTTCAACGCCAGGAACAACTGAAGCGACACATCAAGCAAGCCCACGCAGTTGTCGAGCAGAAGCACGAGCCAATCAGCCAGATTGTCCGCCAGCGGCAGTTGAACCAGCAGAAGCGACTTGCCGAGCAGGACGAGGAAGACGAGAAAACGGAGGACTCCGACAGTGAAACCGACGACGGTGACGAGCAGTACGTGGACGACGCGGAAACTCAGTCGCTGTCGTGTAACGTTTGCGGGGAAAAGTTCGCAGAAGCGCTGGATTTGCTTGCGCACGCGGAAATTCACACCCGATTTGAGCCGCACAAGTGCAACCTGTGCAAGCGATCCTTCCTGGACGAAATCACCATCAAGGAGCACGTCCAGCAGTTTCACAGTCTCGAACTTACCGAAACGTCGTGCGTCGTGTGCGGGAAGCTCTGCAAGAGCCACAACGCACTGCTCAAACACGCCTGGGAACACTCGCGGGAACGGGCCAGCTACGGAACGCACTGCTGCTCCAAGTGTGGCAAATCGTTTCACAACAAGGCACGTCTCAAGCGGCACATGGTCTCACACCGGAACAAAACCGTGAGGTGCGAGGTCTGCTCGGAAGAGTTTCCCGACGGGCGCAGTCTCATGAACCATCGGCACTCGCACACCAAATCGCGCCAGTTCCCGTGTCACGAGTGCGGCAAAACGTTCGGCTCGCGCTCGTCCCAGCAGATCCATCTGAGAATTCACTCCGGCGAGCGACCTTACGGATGCAGATTCTGCTGGAAGGCATTCGCCGACGGGGGGACGCTGCGGAAGCACGAACGTGTCCACACGGGCGAGAAGCCGTACGGATGTTCCGTATGTCCTCGTGCCTTCAACCAACGAGTTGTTCTACGAGAGCACATCCGGTCGCATCACTCGGCGCCCGATCTCAAGCGGGGAACTCAGGCCGAGCCTTACTACTGTTCGGTATGCACCGCCCTGTTTGCCACATCCATGGACCTCATCCAGCACTTGATTCAGCACAGTGACGCGAATACGGCCATGAAGCGCCAGCCGCCAACGTTCCCACGGAAGTACAAACGCCGGAAGAAGATCAAGCAGGACGAGTTGGACAAAGCGGAGCACACTGGCAGCAGCAGGGGCAAGAAGAAGACGTCTGCCAACGAGACGTACGCCGATAGTGATGATCAAGGCGGGGAGGACGATGAAGATTTGCTGAAGAACCCGGCCGAGATTCTGCTCGAGTACGGCGCCGGCAACTCCAACAGGAAGCTGATCGCTTCACCCAAGTTTATCGACTCGTACGAACTGCTCGCCTCAACCGCTCGCGGCAAACCACCCGGGCTGGACGACAGCGGAATCAACCTGTTGAGTAACGTGGTCCTGGTGAACAGCTCCGAGAGCAACAACGTAGAGAAAAAATATAAACCCATCAAGACGGAATCTCCGAAGCGGCGCCACGGAAAACAAACCTCACCAACGGCTGGCCCCGCCCAGTCCGGATCGCGACCACGGATGATACACACGCAGAAAACACGCGTGGCAGCGACGGACGGGAAGCGCAAAACCAAAACCGTCATAACCAAGGACATCAAGAGTCAACCCCTCAACAGTTCCGCCGAGGCGTACCCGGCGTTGGAGTTCAAGCGATCGCGCAATCGTACGGTGCCGACGTACCGGGAAATTCCCTCGGACAAGATTTCCTCCGAAAGCTTCCCCCTGCTGGACGACGGCCAGGACGAAGACGAAGATCCGCAAGATCAGGCTGCGCTGGACGCCCTGTCGAATAGCACCACCCAACGGAACCAGCAGGAGGTTCCTTCGTACGAAGATTTACTCAACCAAAACCTGCTGATGGAGATTTCGCGCAAGGACCGCTACATGGACAAGTTCAACAGCGACATCGTCAACGACCTCGAGGAGATTCTCCGCTCGCCGGTCAAGTCCTCCAACAGCCACGTGCCACCCGCGGACATAATGGCCACACCACGAGCCACTAGTCaatacgacgacgacgccgccgCTAGTTCCTACAGCAAATCAAGTCGCAAGTCGTCCCGCAAGCAACAGTTCAAAAAGACCATCAAAGATGCCTCTCTCACGACGGAACTGCGCAGCCAACGGCTCACCCGCCGCCAGCTGGAGCGCGAAGTCAACTTCCTGCGCGAAGCGTACAACCCGCAGGACTACTCCCAGGTCACCGTCAAGCAGGAAAAGGGCAGCCCGGACAAGCTGTCCGCTATGCTGCTGAACGACATTCAACCGGCGGCTTCGACGTACGTGCCGCCGCTGATTAATCCCAAGCTGGAAAGGGAAACTACACCGGAGCCGGAATCTGAaccggtgctgctgctgccaccgccgccgccgcagctGTTCCAGTGTGAAATGTGCTCGGCCGTGTTTCCAGATCGTTCCCAGCTGTTGCTCCACGTGCCGATACACATTTGA
Protein Sequence: MDHTTFTIWDPTQPNAKMKIINIAGEASQSQYIETVTTASAQTEQIILQTHDGRGFLMNENEISRIDQIPPENLIYMAADDGSLIQGEVVHVQPEEQHQTTEEYMECEVTEEVITDDWVQTDGQECVQVTVDQLGATAVVGAEDDMTVPLPTDQDEYTASRPYPCDFCSRRFRKKVNLMNHMVAHSNDRPHMCNLCGARYLRRCDLLNHLKLHAYVPDDSEEPIRSDPEDDYQYDMVEQQPGPIKRRSPSVDDEPGSLLIPAPAPYKPPKPARAKARPKASQSKSHKKSSTSSAARARQAPPQTESKFNASIEPFVNLPPRYPVMDDRKPFVCQKCGVSFAREKALASHYRIHGGDSQYECETCGDRFWDRSLLQDHIRQRHAASLVAVEPPTLDNSVVGGGGTTIVEEVAADVHEGELVQESTDDGKWHPFCDSCGMVFQRQEQLKRHIKQAHAVVEQKHEPISQIVRQRQLNQQKRLAEQDEEDEKTEDSDSETDDGDEQYVDDAETQSLSCNVCGEKFAEALDLLAHAEIHTRFEPHKCNLCKRSFLDEITIKEHVQQFHSLELTETSCVVCGKLCKSHNALLKHAWEHSRERASYGTHCCSKCGKSFHNKARLKRHMVSHRNKTVRCEVCSEEFPDGRSLMNHRHSHTKSRQFPCHECGKTFGSRSSQQIHLRIHSGERPYGCRFCWKAFADGGTLRKHERVHTGEKPYGCSVCPRAFNQRVVLREHIRSHHSAPDLKRGTQAEPYYCSVCTALFATSMDLIQHLIQHSDANTAMKRQPPTFPRKYKRRKKIKQDELDKAEHTGSSRGKKKTSANETYADSDDQGGEDDEDLLKNPAEILLEYGAGNSNRKLIASPKFIDSYELLASTARGKPPGLDDSGINLLSNVVLVNSSESNNVEKKYKPIKTESPKRRHGKQTSPTAGPAQSGSRPRMIHTQKTRVAATDGKRKTKTVITKDIKSQPLNSSAEAYPALEFKRSRNRTVPTYREIPSDKISSESFPLLDDGQDEDEDPQDQAALDALSNSTTQRNQQEVPSYEDLLNQNLLMEISRKDRYMDKFNSDIVNDLEEILRSPVKSSNSHVPPADIMATPRATSQYDDDAAASSYSKSSRKSSRKQQFKKTIKDASLTTELRSQRLTRRQLEREVNFLREAYNPQDYSQVTVKQEKGSPDKLSAMLLNDIQPAASTYVPPLINPKLERETTPEPESEPVLLLPPPPPQLFQCEMCSAVFPDRSQLLLHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400873;
90% Identity: iTF_00400873;
80% Identity: -