Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: -
Assembly: GCA_015732765.1
Location: NC:210492695-210499783[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.0049 0.14 12.4 0.4 2 23 33 54 32 54 0.96

2 19 0.02 0.58 10.5 0.1 3 23 61 82 59 82 0.93

3 19 4.4e-07 1.3e-05 25.1 0.5 1 23 88 110 88 110 0.99

4 19 0.00046 0.013 15.7 0.1 1 19 115 133 115 135 0.95

5 19 0.00014 0.0039 17.3 0.2 3 23 147 168 145 168 0.92

6 19 0.00021 0.0061 16.7 3.7 1 23 173 195 173 195 0.98

7 19 0.0029 0.082 13.1 2.4 1 23 199 222 199 222 0.96

8 19 6.3e-06 0.00018 21.5 2.0 1 23 405 428 405 428 0.95

9 19 1.4 41 4.7 5.7 1 23 442 465 442 465 0.91

10 19 0.02 0.57 10.5 2.4 2 20 476 494 475 500 0.91

11 19 0.00069 0.02 15.1 0.4 1 23 507 529 507 529 0.95

12 19 3.4e-05 0.00097 19.2 0.4 2 23 536 558 535 558 0.96

13 19 0.00019 0.0053 16.9 0.7 1 23 563 585 563 585 0.97

14 19 9.6e-05 0.0027 17.8 1.6 1 23 591 614 591 614 0.96

15 19 0.01 0.29 11.4 0.7 2 23 629 650 628 650 0.97

16 19 0.00015 0.0043 17.2 1.1 1 23 657 679 657 679 0.97

17 19 0.093 2.6 8.4 0.5 1 23 685 708 685 708 0.92

18 19 1.2e-05 0.00035 20.6 1.3 1 23 721 743 721 743 0.94

19 19 0.00026 0.0073 16.4 3.2 2 23 750 771 749 772 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.0049	0.14	12.4	0.4	2	23	33	54	32	54	0.96
2	19	0.02	0.58	10.5	0.1	3	23	61	82	59	82	0.93
3	19	4.4e-07	1.3e-05	25.1	0.5	1	23	88	110	88	110	0.99
4	19	0.00046	0.013	15.7	0.1	1	19	115	133	115	135	0.95
5	19	0.00014	0.0039	17.3	0.2	3	23	147	168	145	168	0.92
6	19	0.00021	0.0061	16.7	3.7	1	23	173	195	173	195	0.98
7	19	0.0029	0.082	13.1	2.4	1	23	199	222	199	222	0.96
8	19	6.3e-06	0.00018	21.5	2.0	1	23	405	428	405	428	0.95
9	19	1.4	41	4.7	5.7	1	23	442	465	442	465	0.91
10	19	0.02	0.57	10.5	2.4	2	20	476	494	475	500	0.91
11	19	0.00069	0.02	15.1	0.4	1	23	507	529	507	529	0.95
12	19	3.4e-05	0.00097	19.2	0.4	2	23	536	558	535	558	0.96
13	19	0.00019	0.0053	16.9	0.7	1	23	563	585	563	585	0.97
14	19	9.6e-05	0.0027	17.8	1.6	1	23	591	614	591	614	0.96
15	19	0.01	0.29	11.4	0.7	2	23	629	650	628	650	0.97
16	19	0.00015	0.0043	17.2	1.1	1	23	657	679	657	679	0.97
17	19	0.093	2.6	8.4	0.5	1	23	685	708	685	708	0.92
18	19	1.2e-05	0.00035	20.6	1.3	1	23	721	743	721	743	0.94
19	19	0.00026	0.0073	16.4	3.2	2	23	750	771	749	772	0.94

Sequence Information

Coding Sequence: ATGAGTGCTTGTGGTGAAGACGCGCCCCCGGAACCGGTCGAAACGATTGCCACTGCAGATGAGCCCGACACCGAGAAACAAACAACGAAGCAGCTCCGGTGCCAGGTTTGTCCGTCCGTGTTCCGCTCGAAGGCAAGCTACCGGGACCACGTGGACAAGCACGCCGGAGTTGTGTTGGCGTGCGGCAAGTGCGACGCCGTGTTCAAAAGCCGCGAAGGTCGCCGGGTGCACATGATCCTCAAGCACGCCGAAGGGGTCACGTATCGGTGCGAGGAATGTCCGATGATCTTCGCGCGGAAGTCGAACCTGCGGCTGCACATGACCACGCACGGCCAGAAGCCGCACGTGTGCAGCGTGTGCGGGAAATCGTTCGCGCGAATCGAGAGTTTAAAGCTCCACGAGGGGTCCTGCGCCAGTGGCGGATCCAAAGGGCTGGCTTGCACCGAGTGTGGCCAACGGTTCCGGAAGCCAGAGCTGCTTGAAAAGCACCGCGAGCAGGGCCACCCCGAGAAGGACCACCAGTGCGGGCACTGTGGCCAGGGCTTCGAGTCCAAGCGAGCGCTCAGCCATCACGTGCGGGTTCACGAGGGCAAGTTCCGGTGTGGCCACTGCCAGCTGCAGTTTGTCACGGAGAAGGCACTGCGGAACCACGAGCGCCAACGTCACTGGGAAGTGTTGGGCCTCGAGCGGGTGCTGGGAAGTCAGGGCAGGAGGAAAGAAGCGGTGGAGCGGCCAAAGGAGCCGAAGGTGCGCGTGCGAAGAAACAAACACAATCCGTTTATTGGGTTGGAACATTTGCTGGACAAGGAGAAAGATGGGAGCGACGGCAAGGTGGCTGTGACCAAGGAAGAACCGGTAAAAGAGAGGAATCAAACGACGGAAATTGTTATACTCTGCGAAAGGGAAGGAGACAAATATCAGGTTCTTTTACCGGAGGAGCCAACATCAAATCATGAATCTTTGCATAACATTACCATCAAAGAAGAGGAAATCAAATCGGAACCGTCCGACGAGGAAGGCAACAGTGATGCCTTCGGTAGTCCCAACCCTGAATCGGACACGGCAAGTGAACGGGACATATTTGAGGATATCGATGATGAAAATGAACAGTCGTCTGAAATCAACGTCGAGCAAACGCGCCCAAAAGTAAAACGCAAATCAAACCCGGCGGTGCGTCGCAAATCCTACGCCAAAAATCCTCGGCCGGCAAACTTTGCTTGCGAGACGTGCGGCAGGACGTTTTCCTACCAATACCACCTGAAGGCGCACCGGGCCAAAGAGCACGGCGACGGAGTCGTCCCGGTGCCGAACAGAATTCGGGCTCATTTTTGCAAACACTGCGAGAGGAACTTTTCCGTATGGAAAACCTTGGTGTGTCATCTGGAGAAAGCTCACGGCGAGCAGATTGACGAAACAAAGTTCGTTCGATGCACGTCGTGTCACCGAAAGTTCGTCAGTGCCGACGATTTGCGGGTGCATTCGTGCATGAAGGGTTCCCACGTCGGCAAAGATCGTCGGTTCGCGTGTGACTTGTGTGAGAAAACATATGTCAGCGCGCATGGGCTGGAGCGGCATCGTTCGGCCCATCCGGAGCATCAAAAGACAAGCTGTGACGAATGCGGGAAGCCTTTCGCTAGCGAGAAAGAGCTCCAACAGCACAAGAAGCGTGTCCACGTGAAGCCAAGCCATGTGTGTGAGATTTGCAACAAAGCGTTCAAAGGACTGCCGCACCTTAGAATCCACGCTCAAATCCACCAGGAGCAGAAGGCATTCTGCTGTGAGTTCTGTGGGAAATCCTTCGCACAACGGAACGGTATGACGGCACACGTGCGAATCTACCACGCCGAACAGGTGGGCGAAGATGCCGTCGCAGAGCGGGAAATAACATGCGAGATTTGTGCGAAAAAGTTAAAAGGTAAAAGAAGCTACAAACTGCACATGAAAGTGCACGACACTAGCGAGCGCAAATTTCCGTGCAGTTTTTGTGACACGAAATTTATCACAAAGCAAGATCTGGTTCGACACGAGCAACGACACACCAAACAATTCCAATTCCGATGTCGCTTCTGCGGTAAGGGATCAACGCGTCGACGGCAAATCGCGCTGCACGAGGCGCGCATCCACAACTGGCCCGCCCCGTTCGACGTCAACTTGCTGCAGCACAAGTGTGGCGAGTGTGGGCGTAGCTTCGTGTCGAAATCGGCCCTCAAAACGCACGAAACGCTGCACGGGGATGGTTTGCCCGTGCCGTGCAAGATGTGCGACAAGcggttcaaaaatgtcaaatacATGACGTACCACATGAAGATGCACCACGCGGACGGAAGTCCGACGATGAAGCCGCGCAAGAAACGGGCGAAGGTAAGggcggcggtggtggtggccgAGGAGACGCAAGAGGAGGTGGAATTTAAGGCGATTGAAATTCACGAAAATCCGTTGCCTCCGCTGGAGGAGGAAGCTGAGGGTGGGGAAACTAGCGGGGATGGCGGCACGGTGGTTTCCACAACGTTGCAGGTTAAGTCCGAGACTAGTTGA
Protein Sequence: MSACGEDAPPEPVETIATADEPDTEKQTTKQLRCQVCPSVFRSKASYRDHVDKHAGVVLACGKCDAVFKSREGRRVHMILKHAEGVTYRCEECPMIFARKSNLRLHMTTHGQKPHVCSVCGKSFARIESLKLHEGSCASGGSKGLACTECGQRFRKPELLEKHREQGHPEKDHQCGHCGQGFESKRALSHHVRVHEGKFRCGHCQLQFVTEKALRNHERQRHWEVLGLERVLGSQGRRKEAVERPKEPKVRVRRNKHNPFIGLEHLLDKEKDGSDGKVAVTKEEPVKERNQTTEIVILCEREGDKYQVLLPEEPTSNHESLHNITIKEEEIKSEPSDEEGNSDAFGSPNPESDTASERDIFEDIDDENEQSSEINVEQTRPKVKRKSNPAVRRKSYAKNPRPANFACETCGRTFSYQYHLKAHRAKEHGDGVVPVPNRIRAHFCKHCERNFSVWKTLVCHLEKAHGEQIDETKFVRCTSCHRKFVSADDLRVHSCMKGSHVGKDRRFACDLCEKTYVSAHGLERHRSAHPEHQKTSCDECGKPFASEKELQQHKKRVHVKPSHVCEICNKAFKGLPHLRIHAQIHQEQKAFCCEFCGKSFAQRNGMTAHVRIYHAEQVGEDAVAEREITCEICAKKLKGKRSYKLHMKVHDTSERKFPCSFCDTKFITKQDLVRHEQRHTKQFQFRCRFCGKGSTRRRQIALHEARIHNWPAPFDVNLLQHKCGECGRSFVSKSALKTHETLHGDGLPVPCKMCDKRFKNVKYMTYHMKMHHADGSPTMKPRKKRAKVRAAVVVAEETQEEVEFKAIEIHENPLPPLEEEAEGGETSGDGGTVVSTTLQVKSETS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400806;
90% Identity: iTF_00400806;
80% Identity: -