Cqui005496.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex quinquefasciatus
Gene Symbol
ECU03_0790
Assembly
GCA_015732765.1
Location
NC:71486735-71506267[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00043 0.012 15.7 4.2 1 23 108 130 108 130 0.98
2 16 4.5e-06 0.00013 22.0 1.3 1 23 136 159 136 159 0.97
3 16 0.0003 0.0085 16.2 0.1 1 23 166 189 166 189 0.98
4 16 0.00012 0.0033 17.5 1.6 1 23 224 247 224 247 0.98
5 16 0.068 1.9 8.8 2.8 1 23 253 275 253 275 0.93
6 16 4.6e-08 1.3e-06 28.2 1.4 1 23 364 386 364 386 0.99
7 16 2.7e-06 7.6e-05 22.7 0.8 1 23 392 414 392 414 0.99
8 16 0.0028 0.081 13.2 1.9 1 23 497 519 497 519 0.98
9 16 3.3e-07 9.4e-06 25.5 0.3 1 23 525 547 525 547 0.99
10 16 0.026 0.75 10.1 0.2 1 15 614 628 614 638 0.85
11 16 0.0019 0.056 13.7 2.1 1 22 644 665 644 668 0.89
12 16 7e-07 2e-05 24.5 0.8 1 23 729 751 729 751 0.99
13 16 0.00022 0.0062 16.7 1.3 1 23 757 779 757 779 0.98
14 16 0.0021 0.06 13.6 3.9 1 23 970 992 970 992 0.98
15 16 1.2e-08 3.4e-07 30.1 0.7 1 23 998 1020 998 1020 0.99
16 16 8.3e-05 0.0024 18.0 0.5 2 23 1027 1049 1026 1049 0.97

Sequence Information

Coding Sequence
ATGAACGAGATCGAGGTGAAGCAGGAAAATTTTGCGGACGTGGCCAATGGCCGGCCTTCGTCGGCGCTGCAGCAGGATGAAAATGGGGAAGATGACGGCGAGATGGTCGTCGGAATCGACGCGGACCACATCAACTTTCTCACCAGTATGGCGTCGGACGATTCGCTCGACTGCCCACCGGAAGTTGCCGCGAGAGGTCACGGTGGCCAAGCGGGCGAGTACGGCGAAGAAGACGAGGAGGACGTGATGGCCGCGGCCGAGTCGATTCTGCAGAAAACGGCCAAACGAAGTGGTGGTGGCGCCGCTGGAGCTCAGCAGTTTTATCACTGCCAGTACTGCAACAAGACCTTCACCTGGCTCAAGTCCCTGACGGTGCATCTTCGCACGCACACCAACGTTAAACCGTACAAATGCGAGCTGTGCGATCGTTCCTTCGTGCGGTCCGACTATCTCAAGTATCACATTCTCAAGAGCCACGAAACGACGGAACAGGTTTTCACGTGCGGAGCGTGCGGCGGAGTTTTTGCCACCAACCGCGGCCTCCTCCGACACATCCGCACCGAACACGACGGCCATCCCACCGGCGATGACGAGCTCAACCCAAACGCCAACCCAACCGCCCCAGAATCCGACTCGGAATCAATCCCCGACGCCGACGAGCACGGCAAATTCTCCTGCACGTACTGCGACGAGTGCTACGACACCCGGGAACCGCTCGCCGTCCACATGCGGCGCCGTCACCTCGGCGACAAGCCCTTCCGCTGTGACCTCTGCCCCAAGTCGTTCATCCGGGTGGACTTTCTCCAATGCCATCGCTCGAACCACCTCAAAACCATGGACTATCGCCAAAACGGCGCCAACGCCAAACGACCCCGCATCAGCTTGAAAAAGCTCGAAGATCTGGTCCCGTCGGCGTCCGCATCCCGGGCGGAAtcgagcgacgacgacgacgacggttccGACTCGGACGGGGACAGCAGCTCATCGGACGCGGAAAATCCGCAGCATGATCAGCAGCAGCAAAGTGAGGAGCAGCGCAGTTTGTTGGCGGCGCTGTTGACGCAGGTGTCCCGTACCGAGAACGATCGATATCAGTGTCCGCGCTGCGACAAGACGTTCACGCAGGAGTCGACGCTCAAGGTGCACCTGAGGACGCACACAGGCATCACCCCGTTCAAATGCCCGCTCTGCGATCTGGCATTCATCCGATCTGACTACCTTAAGAACCACCTGAAGAAACACATCGAAGACAACGGCGAGGACCCGGGAGCACCGGGCGCGATCGACCCGTCCACCTTTTCGTATAGCAGTTCAACGTACGCAAGCGGTCCCAGCGTCAGCGGCACTGGCAGTGGTGGTGGTTCGGTGTCCCTGTTGAAACCGCTTGCGGCAAGAACCCAATCGACGGGCATTTCGCTGCTGAAACCTCCGGAGGAGCGAAAACCCCCCGATCAACCCGAGTACTGCATCCGGACGGAGGATGGCAAGTTTATGTGTACGGCGTGCGAGCGCGTGTTTAGCCACCAGCAAACGGTCCGGATCCATTACCGGATACACACCAACGAAAAGCCCTACAAATGCCCGAGCTGTCCGGAGTCGTTTATCCGGTCGGACTATTTGGAGCGGCACATGAAGGTGCACTGGAAGGACGGCGGGCCGCTCGGACCGTTGCCACCGTTGATGGTTCCGACCAAAAGTGGGGGCAGCGCGTTGGCATCGGCTTCCGCTTCGGTGGGTGCCTCGGACAGCAGCGATTCGACGAGTCCGCAAAAGCCGACGATTGGCCGGGCCGGGCTGCTGCCGGAGAATTACCACTTTGTGGAGGCCGGCGATGGTCAGTACGCGTGCAAGATTTGTGATCAAGTATTTTCCCAAAGCGATCAAACGAGCATTCGGAAGCATGCGTTGACGCACACCGAGGAGAAGCCGTTCTTCTGTGATGTGTGCGATCGCTCGTTCAACCGGGTTGACTACCTGAAGGAGCACTTCAAGTCGAAACGGCACCGACAGGCCTTGGCCGAAGCCAGCGGGGACGCAATGGCGATGACAATGGCCGAGGAGGACGACGACTCGATGACGGACACGAGCATCACCGGCAGGATGGCCAAAATCAAGTCCCCCATCAGTCCGATGACGAACGCGATCGCCGACCGGATGGAGTTCCAGCGGACGGAGGACGGCCGGTACAAGTGCACCGACTGCGACAAGACGTTCGTGACGGCCGTTACGCTTAAAATGCACCTCCGGCTGCACACCGGAGAAAAGCCGTACAAATGCTCACGCTGCAGCATGGCCTTTATCCGGTCGGACTACCTGAAGACGCACGAGAAGATCCACCGGCAGGAGGCGTACATGGCCAACCGGCAGCTGTACTCGCGCGACCAGAGCATTGCATCCGGCGATGAGTACGACGACgatggccagcagcagcagcagcagcagcagcaacagtacGAAGAGGGCGAGTACACGGGACTGCCGTCGCAGCTTTATCCTCAGCAGAACCAGCAGGTCAAGCAGGATCCGGAGCTGATCATTGAGGCGTCGGTGGGACTCCACGAGCAGGACGGTGGTCCGATGGTCAAGGAGGAGGAGCAGGATGAGGATGAGGACGATGACGACGAGGACAACGGTGGGGACGAAGAGGAAGAGGACGAGGAGGAGAGTGAGGACGAACAGGTCATTGAGGTGATGGTCAAGGAGGAGGACtcggacgacgacgatgatgaggaGGAGCAAGGAGGTGACGACGACCAGAACGAGGAGGACGAGGAGGGTGGCGACGAGGAGGAGGACGAGCATGAAAACAACAACAGCTACGAAAACGAGGACAGCTCGTCCCGCGTGAGTGGCGGCGTCGGCGGAGTCGGTGCCCACTTGGAACAATCGTCCGGCCCGCGGTCCAAGCACCGGTGTCACCTGTGCAAGAAGGAATTTGCATGGCCAAAGTCGCTCAAGATTCATCTGCGCACGCACACCGGCGAACGGCCGTACGAGTGCGAAATTTGCGGGAAAAGCTTCACCCGGTCGGACAGTTTGAAGGCGCATCGAAACACCCACGGGGACGTTCGGGTGCTGCAGTGCCATCTGTGCGACGCCACCTTCGTCAATGGAAGTGGGCTGATACGGCACCAGAAGACGGAACACGGCGTTGAACCGTTGGACGCGTAA
Protein Sequence
MNEIEVKQENFADVANGRPSSALQQDENGEDDGEMVVGIDADHINFLTSMASDDSLDCPPEVAARGHGGQAGEYGEEDEEDVMAAAESILQKTAKRSGGGAAGAQQFYHCQYCNKTFTWLKSLTVHLRTHTNVKPYKCELCDRSFVRSDYLKYHILKSHETTEQVFTCGACGGVFATNRGLLRHIRTEHDGHPTGDDELNPNANPTAPESDSESIPDADEHGKFSCTYCDECYDTREPLAVHMRRRHLGDKPFRCDLCPKSFIRVDFLQCHRSNHLKTMDYRQNGANAKRPRISLKKLEDLVPSASASRAESSDDDDDGSDSDGDSSSSDAENPQHDQQQQSEEQRSLLAALLTQVSRTENDRYQCPRCDKTFTQESTLKVHLRTHTGITPFKCPLCDLAFIRSDYLKNHLKKHIEDNGEDPGAPGAIDPSTFSYSSSTYASGPSVSGTGSGGGSVSLLKPLAARTQSTGISLLKPPEERKPPDQPEYCIRTEDGKFMCTACERVFSHQQTVRIHYRIHTNEKPYKCPSCPESFIRSDYLERHMKVHWKDGGPLGPLPPLMVPTKSGGSALASASASVGASDSSDSTSPQKPTIGRAGLLPENYHFVEAGDGQYACKICDQVFSQSDQTSIRKHALTHTEEKPFFCDVCDRSFNRVDYLKEHFKSKRHRQALAEASGDAMAMTMAEEDDDSMTDTSITGRMAKIKSPISPMTNAIADRMEFQRTEDGRYKCTDCDKTFVTAVTLKMHLRLHTGEKPYKCSRCSMAFIRSDYLKTHEKIHRQEAYMANRQLYSRDQSIASGDEYDDDGQQQQQQQQQQYEEGEYTGLPSQLYPQQNQQVKQDPELIIEASVGLHEQDGGPMVKEEEQDEDEDDDDEDNGGDEEEEDEEESEDEQVIEVMVKEEDSDDDDDEEEQGGDDDQNEEDEEGGDEEEDEHENNNSYENEDSSSRVSGGVGGVGAHLEQSSGPRSKHRCHLCKKEFAWPKSLKIHLRTHTGERPYECEICGKSFTRSDSLKAHRNTHGDVRVLQCHLCDATFVNGSGLIRHQKTEHGVEPLDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400801;
90% Identity
iTF_00400801;
80% Identity
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