Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:15144886-15153266[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.17 5.2 8.2 2.7 1 23 342 365 342 365 0.93

2 19 0.14 4.4 8.5 0.1 1 20 374 393 374 395 0.94

3 19 0.0039 0.12 13.4 0.1 2 20 458 476 458 477 0.93

4 19 0.0037 0.11 13.5 5.9 1 21 657 677 657 682 0.93

5 19 0.088 2.7 9.1 0.4 1 21 747 767 747 768 0.95

6 19 2 61 4.9 0.9 3 23 880 901 879 901 0.94

7 19 3.9 1.2e+02 3.9 0.6 2 20 944 966 943 967 0.91

8 19 1.4 43 5.3 0.7 1 20 1000 1020 1000 1021 0.85

9 19 9.2 2.8e+02 2.8 2.5 1 23 1079 1103 1079 1103 0.94

10 19 0.0062 0.19 12.8 0.3 3 21 1115 1133 1114 1134 0.94

11 19 2.8 87 4.4 0.5 3 23 1205 1226 1204 1226 0.96

12 19 0.00098 0.03 15.3 0.9 2 21 1236 1255 1235 1256 0.95

13 19 0.48 15 6.8 1.1 2 19 1307 1324 1306 1329 0.91

14 19 8.2 2.5e+02 2.9 0.4 2 21 1451 1470 1450 1471 0.92

15 19 0.012 0.38 11.8 0.2 3 23 1504 1525 1503 1525 0.92

16 19 0.0013 0.041 14.9 0.8 2 23 1562 1584 1561 1584 0.96

17 19 0.62 19 6.5 0.2 1 23 1590 1615 1590 1615 0.92

18 19 6.8e-05 0.0021 18.9 0.1 1 23 1621 1643 1621 1643 0.97

19 19 0.18 5.5 8.2 0.3 1 21 1649 1669 1649 1670 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.17	5.2	8.2	2.7	1	23	342	365	342	365	0.93
2	19	0.14	4.4	8.5	0.1	1	20	374	393	374	395	0.94
3	19	0.0039	0.12	13.4	0.1	2	20	458	476	458	477	0.93
4	19	0.0037	0.11	13.5	5.9	1	21	657	677	657	682	0.93
5	19	0.088	2.7	9.1	0.4	1	21	747	767	747	768	0.95
6	19	2	61	4.9	0.9	3	23	880	901	879	901	0.94
7	19	3.9	1.2e+02	3.9	0.6	2	20	944	966	943	967	0.91
8	19	1.4	43	5.3	0.7	1	20	1000	1020	1000	1021	0.85
9	19	9.2	2.8e+02	2.8	2.5	1	23	1079	1103	1079	1103	0.94
10	19	0.0062	0.19	12.8	0.3	3	21	1115	1133	1114	1134	0.94
11	19	2.8	87	4.4	0.5	3	23	1205	1226	1204	1226	0.96
12	19	0.00098	0.03	15.3	0.9	2	21	1236	1255	1235	1256	0.95
13	19	0.48	15	6.8	1.1	2	19	1307	1324	1306	1329	0.91
14	19	8.2	2.5e+02	2.9	0.4	2	21	1451	1470	1450	1471	0.92
15	19	0.012	0.38	11.8	0.2	3	23	1504	1525	1503	1525	0.92
16	19	0.0013	0.041	14.9	0.8	2	23	1562	1584	1561	1584	0.96
17	19	0.62	19	6.5	0.2	1	23	1590	1615	1590	1615	0.92
18	19	6.8e-05	0.0021	18.9	0.1	1	23	1621	1643	1621	1643	0.97
19	19	0.18	5.5	8.2	0.3	1	21	1649	1669	1649	1670	0.95

Sequence Information

Coding Sequence: ATGGATCAAGATCTCGACTTTTTTGTGCTGGACCCCCGTTGCCGCCTGTGCCGGTCACCGGATGCGACCGGCGGCAGGACGTTCGTGAACGAGAAGGACCACCAGCAGCGCCGGCTCGTGTCGGAAATGATCAGCAGCTGCACGGCGGTCAAGATCTACGACCACGACCGTTTGCCCCAGCACGTTTGCGGCCCGTGTATGGAGAAACTCCGCGAGGCTTACGCGCTGTGGCAGCGGTGTCTGGCGGGCCAAAAGAGCGATTTTCGGTGCCAGGCGGGGAAGGAGGATGAATTCTTGCGGTGTCGGATCTGTCACGCAGAAGAGTGCGATGAGCTGTTTTCGCTCGATTGTCCCGGAATGGGCGAGGAAGTGCCGATTGGCGACATGCTGCAAGATTTTGCGAATGTGATGGTTGTTCCCGGGGACGGACTGGCTGCGTACGTTTGCGACGGTTGTCTGGAGCTGCTGGAGAGGGCGAGGGTGTTCAAGCGGGAGTGTCTGCAGGCGGAAGTTGCGTTTTTGAACGATACCGTTCACGCTTGGGAGAAAATGGAGTTTCAGGAAGGTCAGCCTTCGCATCTGGTGGTGGAGTTGTTTGCGAAACCAATCTTTGAATCGCCCAAGCTGGTTCGATGTTCGGTTTGTAGCTTGAAACGCACCATTCGTCAGATTGCGACGCACTGCGAGGGATGTAAGCTAGATTTTGATGGCCTGGAGCCAAGCAGTGAGTGTGAAACAGATGAGAAGGTTGAACTGCTGGTGGTCGTGGACTCGGGCAACGATGAAGAGAGCGAGGTTCAGGCGAAACGGCCGCGGATGGCAGACAAGAAGCAATCACCGGTCAAACGGGTTGTGCCACAGTCTTCAGCTAAGACCATGCAAAGGAATCAAGAGGATCCAAACGCGGTGCATGCCCGAAGCATTTCCCGAAATTTGACAAAGTTAAACCAGAAGATCGAGGAACACTTCCAGATTGTTTCGAGTCCGCCGGGTGCCACCTACCAGACCATGCGCCTCAAATCGTTCCTATGCTGTGGCTGTAACCGGTTTCTGATTAACCAAGAAGCTTTCCGTAAGCACTTGCGTGAATTTCACCCCAAACCAACGATCCGATCGGAATTCGTCTGCGGCATTTGCAACTCCGCGTTCGGGTCGAAGAAGCTCTTACTGGCGCACAGGGACAAACTGGGCGGTCGGTTGTACAACTACTGTAAAATCTGTGACATCGTTCTGCTGGAGGAGCGCAGCTTCGTGCGGCATCAAATGATGAACCACTTGACCGATCGGCAGTTGAAGGAAATCGAGCAGCAATTCATCAGGAACGTTACGAGCAAGTGCCGATCCGTTGAGTCGGTGCCGGATGGCGACGCAACGTGTGACGATTGTGGAAAGAGCTTCGCCACGGAGGAAGACCTGTCCGGTCATCGGTACGAGAGCTTCCAGTTCACCTGTCAGCAAAAGGGCTGCAGTTACGTGACCAAGAACAGAGAGTTTATGATTGTGCACTGTGTCATCGGTGACCACAGCAAGCAAAAGTCCGAATCAACGACGAGCATCGTCGAAGAGCCTCCAAAAGAACTCGACGAAGAAACTTTCATGGTGGAACTGGAAGATGGCGTCGAGGACGCAGACTCTGACTGGGAGCCCGACCTCATCTACGACACGGAATGGATTCGTCCGGATAGCGTCAAACGCCAGGTAAAGCTTCAATTCCCCAGCAAAAATCCGTCAAAGCCACAGCTGGATGAGGATGCGATCGCAATCTCGTCGTGTCGCGCCAACTTGGAGAAAAGGTCCCTGAAGATGGAGGACGTGTTCGAACTACTCGAGACCAATCCGAGCGGCATTCATCAGTACGTCCGACGGAAGACGCCCTTCTGCTGTGGCTGTAATCGGTTCGTCCTCTCCAACGAAGCATTCCTGAAGCACCTGGAAACGTTCCACCCCAAAAAGCCAACGGATTCCAAATTCGTTTGCCACATCTGCCACACGTCGTTCACGGTGAAGAAGAACTTCAAAGCCCACATAGACAAAAAGGACTGCCACGTGTACAACTACTGCATACCGTGCGATAAAATCGTGCTGGACGAAAAGACCTACGTCAAGCATCAGCTCAGCGTGCACCTGACGAACCGGCAAAAGGCGGAACTCGAGAAGCAAATCGCACCGGTAACCGTAAAACGGTGCACCTACCACTCGCGCATCTCCTTCTCCGGACTCATGGGGAAGCGCACGAACTTCCGGTGCAACTTCTGTCGGCGTTACTTCGCGTCGCAGGCCACCCTGGACGGGCACATGCAGGACGTCGTCGAGTACGCGTGTCTGGCCGAGGGTTGCGAGATCCAGTCGCGCCACCGCCAGAGCATGATCGTGCACTGCAGCCTGGGAGATCACCGCAAGCAGCCGAAGGGCGAGACGAAGCAGTTGAACTTCCGGCAGAGGTCGATGCTGTTCGACGAGGCGCTGCCGGTGGCGGCCGAACGGGTCGAGGACCTGTCTCAAGTGGCCATTCCCATGAAGCAGCTGCGCATATTTTTGAAGGGAAATTCGCTGCAAATGGAAGACATATTCGGGATCGAGAAGGACATCGACAACAAGTACGTGCACTGCATTAAGCTGCTGCGCAAAAAGCCGTTGTGCTGCGCCTGTAACTTGATGTTCATGAGCGAACAGGCGCTGTCCAGCCACATGCAGAGCGAACACACGGAGCGTCCCGAGCCCGGTGTTGACCCGGAGCTGGTTTGCAAGCTTTGCTACACGGTGTTCGGGAAGCGAGCGTTGCTCAAGTTTCACACTGACCGGCTGCAGACGAAGAGCAGTCAGTTCACCTACTGCAAGCTGTGCGATGCGATTGTGCTTGCGAAGAGCTTCACCCGCCACAACTTTAAGCGGCATTTGACGGATGAGAAGATGAGCGAACTCGAGGGCCAATTCACTGCGGTGTCGTCGTACGGCTGTCGAGATGCCGATTCCCTGACGGAAATCGACGAAGGTAGATACAAGTGCGCGTGCAAGTGCGGGAAAAAGTTCGAGTCGATTCTTTCCGCCAGAGCTCACCAGGCCGGAAGTCAGGACGTGATGCTGTACTGTAAAGTCGAGGGCTGCCGGTTCCAGACCAGCAAGAAGATGGAAATATTTGAACACCTTATGGAGGAAGCTCACGAGGTGCCAGCGGACCCCAAAGATCAAGAGGCAGATGATGAGATTTGCTTCTTGGAACGGGATATGGTTTACTTTAAGTGCTGTTTTTCGAGGTGCTTCAGGAAGTTTGCAGCTGAAGATAGTTTGCTCGCACACTTTGCGACACATCCTCCTGCACCGGTGGATCTGGAGCCCAATATATGCCACATCTGTAGAGAGACTTTTTCAAGCGATGACGATTTTCAGGCTCACATGGATCGAAGCTATACCGTCAAAATGTTCCGATGCGTCAATAAACCTTGCAAGTATCAGTCCGAGTTTTTGCCTAACGTCCAGTTGCACTACAAGTCGTGCAAAGGTCTCGTCCTGCGAAAAGCATGGAAATGTCCAAAGGACAAAATTCCGGAACATTTAGTGAAAGCTGGCCAACTGGACGAGATGATAGATATTATCGAAGGCAAAGGACCGTTCTGCTGCGGTTGCCGTCAGGTTCTGGGAAGTGAAGCTGAACTCCAGGAGCATCTGCAACGGGAGCACGCGACCCGTGATCCGTCTCGTCCCTTGCACTGTCCCACGTGCAACAAAGGCTTCAAGCTAAAGAGCTTCCTGGAGAACCACATGAGGGAGTCTGCTGAGCGTAGATATTACCACTGCCGTATTTGCAAAACCCTGCTGTTGAACGAGCTGCAGGTGAAGCATCACAAAACGTACATCCACGCCTTCGAAGACCCGTCCGAGCTCACGGAGTTCTACGACACGATCACGTCGGATTTGCTGCCCTGCTGCGGCTGCGATGCAAAGTTCGCGACACAGGATGAGCTGGCGCTGCACTGCTCACTCGCCCATCCGGCGCCCAGTATCGTAAATCGGCTGCTGTGTCCCAACTGCCACCTGCAGCAGTCAAGTTTGAAGTCGATGACCAGCCACTGCGCCAAGTACGGCAGTAAGACGTACTACAAGTGCAAGattggTGACTGCAGACTGCAAACAAAGATTTTGTCCATAATTCAACGGCACGTGTCGGCGGCGTCGCACGAGGACCAGGGGGGAAGTTACCGAAAATATCTGGAGCACCAGCAAACGTTCTACTGCTGCGTGGTGAATTGTACGTTTTCCAGCGAGTTGTACGATTTGCTCATCGATCACGGTATCGCCGAACACGCGAAGGAACGCGAGCATCTCAGCGCCAAGCGCAGGGATCGACCACTCACGTGTCCCGTGTGCTGCAAAGGTTTCAACGAGGAGAAACAAATGATCAACCACCGAAACGGCGCGATTCTCGTGGCCtgtgaaatttgcaaaaacaaGACGCCAGCACCGGACTTTGCTGCCCACCTGGAAGAGTGCAGGCGAACCTACTCGAAGGCGTGCCCACATTGTCCAGAAGTGTTCGCGACCTATGGCGAATTCGTGAAACATAACAACCAACTCCACGGACACACAAGACCTAAGAAGAAAGTAGTTTGCAGCATTTGCGGAATGCTGGTGGTTGAAAATATACTGGCAGATCACATAGCATCGCACGAGAACAAGCGTGCCTGGAAGTGCAACCAGTGCTCGTTAGCGTTCAACACCAAAACTAATCTGAGCCTGCACGAGCGTCGCGTCCACACCACCGAGCGGAAGTACCGGTGCACGGTTGTGGGCTGCGACAAAACGTACCGCTACGACATTGACCGCGTGCGGCACGAAAATGTGGTACATTTCAACCTGAAGCCGTTCGCGTGCGCCGAATGTCCGGAAGCGTTCGTGCGAAATCGTGACCTGCAGCTGCACATGCGGCTGCACACCGGCCGGAAGCTGTACACCTGCCAGAGGTGCCGGGCCGAGTACGACCGGAAGAGCGAATTTGTGGCGCACCAGGAGCGGTGCGGGGAAGCAAGGTACGACGAGGACGTTTCGGCGTACGAGGAGTACATTGAGGAGGAGATTGTTTGA
Protein Sequence: MDQDLDFFVLDPRCRLCRSPDATGGRTFVNEKDHQQRRLVSEMISSCTAVKIYDHDRLPQHVCGPCMEKLREAYALWQRCLAGQKSDFRCQAGKEDEFLRCRICHAEECDELFSLDCPGMGEEVPIGDMLQDFANVMVVPGDGLAAYVCDGCLELLERARVFKRECLQAEVAFLNDTVHAWEKMEFQEGQPSHLVVELFAKPIFESPKLVRCSVCSLKRTIRQIATHCEGCKLDFDGLEPSSECETDEKVELLVVVDSGNDEESEVQAKRPRMADKKQSPVKRVVPQSSAKTMQRNQEDPNAVHARSISRNLTKLNQKIEEHFQIVSSPPGATYQTMRLKSFLCCGCNRFLINQEAFRKHLREFHPKPTIRSEFVCGICNSAFGSKKLLLAHRDKLGGRLYNYCKICDIVLLEERSFVRHQMMNHLTDRQLKEIEQQFIRNVTSKCRSVESVPDGDATCDDCGKSFATEEDLSGHRYESFQFTCQQKGCSYVTKNREFMIVHCVIGDHSKQKSESTTSIVEEPPKELDEETFMVELEDGVEDADSDWEPDLIYDTEWIRPDSVKRQVKLQFPSKNPSKPQLDEDAIAISSCRANLEKRSLKMEDVFELLETNPSGIHQYVRRKTPFCCGCNRFVLSNEAFLKHLETFHPKKPTDSKFVCHICHTSFTVKKNFKAHIDKKDCHVYNYCIPCDKIVLDEKTYVKHQLSVHLTNRQKAELEKQIAPVTVKRCTYHSRISFSGLMGKRTNFRCNFCRRYFASQATLDGHMQDVVEYACLAEGCEIQSRHRQSMIVHCSLGDHRKQPKGETKQLNFRQRSMLFDEALPVAAERVEDLSQVAIPMKQLRIFLKGNSLQMEDIFGIEKDIDNKYVHCIKLLRKKPLCCACNLMFMSEQALSSHMQSEHTERPEPGVDPELVCKLCYTVFGKRALLKFHTDRLQTKSSQFTYCKLCDAIVLAKSFTRHNFKRHLTDEKMSELEGQFTAVSSYGCRDADSLTEIDEGRYKCACKCGKKFESILSARAHQAGSQDVMLYCKVEGCRFQTSKKMEIFEHLMEEAHEVPADPKDQEADDEICFLERDMVYFKCCFSRCFRKFAAEDSLLAHFATHPPAPVDLEPNICHICRETFSSDDDFQAHMDRSYTVKMFRCVNKPCKYQSEFLPNVQLHYKSCKGLVLRKAWKCPKDKIPEHLVKAGQLDEMIDIIEGKGPFCCGCRQVLGSEAELQEHLQREHATRDPSRPLHCPTCNKGFKLKSFLENHMRESAERRYYHCRICKTLLLNELQVKHHKTYIHAFEDPSELTEFYDTITSDLLPCCGCDAKFATQDELALHCSLAHPAPSIVNRLLCPNCHLQQSSLKSMTSHCAKYGSKTYYKCKIGDCRLQTKILSIIQRHVSAASHEDQGGSYRKYLEHQQTFYCCVVNCTFSSELYDLLIDHGIAEHAKEREHLSAKRRDRPLTCPVCCKGFNEEKQMINHRNGAILVACEICKNKTPAPDFAAHLEECRRTYSKACPHCPEVFATYGEFVKHNNQLHGHTRPKKKVVCSICGMLVVENILADHIASHENKRAWKCNQCSLAFNTKTNLSLHERRVHTTERKYRCTVVGCDKTYRYDIDRVRHENVVHFNLKPFACAECPEAFVRNRDLQLHMRLHTGRKLYTCQRCRAEYDRKSEFVAHQERCGEARYDEDVSAYEEYIEEEIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -