Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:15120396-15132594[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0034 0.1 13.6 0.2 2 19 358 375 357 375 0.96

2 12 0.0058 0.18 12.9 3.3 1 21 471 491 471 492 0.94

3 12 0.57 18 6.6 5.1 3 23 567 588 567 588 0.97

4 12 0.4 12 7.1 0.0 2 20 603 621 602 623 0.90

5 12 0.059 1.8 9.7 0.9 1 23 676 699 676 699 0.96

6 12 0.0071 0.22 12.6 2.1 1 20 711 730 711 732 0.94

7 12 0.15 4.4 8.5 0.0 3 23 848 869 846 869 0.94

8 12 0.29 8.9 7.5 0.1 3 23 882 901 880 901 0.94

9 12 0.003 0.092 13.8 0.3 2 23 908 929 907 929 0.94

10 12 0.19 5.7 8.1 0.5 3 23 937 959 936 959 0.91

11 12 0.00055 0.017 16.1 0.3 1 23 967 989 967 989 0.98

12 12 2.6 80 4.5 0.0 1 20 995 1014 995 1016 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0034	0.1	13.6	0.2	2	19	358	375	357	375	0.96
2	12	0.0058	0.18	12.9	3.3	1	21	471	491	471	492	0.94
3	12	0.57	18	6.6	5.1	3	23	567	588	567	588	0.97
4	12	0.4	12	7.1	0.0	2	20	603	621	602	623	0.90
5	12	0.059	1.8	9.7	0.9	1	23	676	699	676	699	0.96
6	12	0.0071	0.22	12.6	2.1	1	20	711	730	711	732	0.94
7	12	0.15	4.4	8.5	0.0	3	23	848	869	846	869	0.94
8	12	0.29	8.9	7.5	0.1	3	23	882	901	880	901	0.94
9	12	0.003	0.092	13.8	0.3	2	23	908	929	907	929	0.94
10	12	0.19	5.7	8.1	0.5	3	23	937	959	936	959	0.91
11	12	0.00055	0.017	16.1	0.3	1	23	967	989	967	989	0.98
12	12	2.6	80	4.5	0.0	1	20	995	1014	995	1016	0.85

Sequence Information

Coding Sequence: ATGGAAGACCTGTGCCGCATTTGCCGCTCCGCCGAGGTGGACGAGCTGATTTCGGTATCCTGCACGGTGGCCTCGCAAAACCGAACCGTCGGCGAAATGATCATCGCCGTGATGGGTTTGCGCTTCAGCCTGACACAGTACGACCGCATGCACCGGGTGCCGGGTCAGCTGTGCGATCGGTGTCTGGCGCGGTTGGACCGCGCGTACGCGATATGGAAACGGTGCCGGTTCGCGAGTGGGTTGGCACGGTGCAAGAAGGGCGAGGAGGACGGGTACTTCCGGTGTCGGATTTGCGCGTCGGGTGACGCCGACGAGCTCATCTCGGTGACGTACGTGTGCAAGGCGTGGAACGTCCAGATCGTGACGATGGTGTACGAGCTGACGGCCATGCGGTACAAGGAGGGTGATGGTCTGCCGGCTTATGTTTGCGCGGAGTGTTTGAAGAGTTTGGGTGTGGCGTACGAGTTTCGGCGGGATGCTTTGGAGTCGGCGAAGGCATTTGAGGGGGCGTCGATTGACAGGTATCCGTGGCAGGCGATGCAGTTTCAGGTGGATCAGCCGGAACGCTTGGTGGTTGATTTGGCGAGTGAAGCCCAGTTGGATATGAAGGGTGGCGTCTATTGTTCGGTTTGCAGGGCGGTGATTGCCGCTGAGGAGTTGGAGAAAACATGCGCAGGATGTATGCTGGAGTTTAGCAATTACGACGCGATTGTTGGGAAAATTGCCAACTATGGCAAGCGTGAGATCAAAACGGAGAAGGGTATGGATGACGGACCGGCTTACGAATCGGTTGATGAAGTCGAAGTTGACGAACAGTCGAAGGCAATCGAGGATGATTTGAGCGAATTCGTACAATTTAAGCAAGAAGATTCGCCGCTGGAGTCCAGTGATGAAGCCTATCTACCAAAGACCATTAAGCCACTTCAGAAGACAAATTTCCACATCGAGAACACGGTAGAATCCGTTTGCTGCGTGATGGGTTGCGTTTGGACCGGATCGCAGGGTGAGCTGCTGTGGCATCGGAAGCACCTGCACTCGGATTTGGCCAAATTAAAGTCGGAAAGCCAACTGATGTGTCGCTACTGTGACAGATCTTTCCCAAGTTTGGGCCAATTGAACAAGCATTGCGACCGGAAGCGGTCCATTTTCAAGTGTCTCTTCAATGAGTGCACGTTTACGGCGAAAAATATGGGCGGAATCGTGCTTCATTACGCGAAACACGGGTCGGATAAACCGGCCATTGGTCCTCCGGTGATTGAAGCCCATCAAGCTGAAAAGCACATCGCGACGGAACACATTACGGAGTACGCATGCTGCGTTACGGATTGTCACCAAACTGGAACCATGGACCAGATACAATCCCACTACAACAGAATTCATCCGGATGGGATGGAGTGCAGAAACGGGTCCTATTACTGTCAGCACTGTGAGCGAACTTTCCCAGATACGGACACTTTGCGGCACCACTTTCAACGGGAATCGACGATGTACAAATGTACCATCGATGGATGTTGCCTTTCGAGCAAGGTGAAGCAAATCCTGATCAATCACTGCACGGGACCACACCAGAAAGTGTTCAAGATCAAGCCGGTCAACACCCTTCGGCCAAAGGTCACTCCCCGTCCCGACTTGAAATGCTTCAAAGTGGTCGGTTGCGTGGACGACTGCATCGACGTGCTCAGCCGGAAGGGCGAATGGTGCTGCACCTGTCACAAACTGTTCGCCTCGGAAGATTATCTGCGCCAACACCGGGACACAACACACCCCGTCCAACCACCGTCGATGTTCGAAGATCAGCACCCTTTCCTGTGCATGCAATGCAACGCTGGTTTCTCCGACGCAAACGCCCTCACGGAACACGTGGCTAAAAATTCTCAACAGAATCACTACTACTGTCGCGGCTGCAAGTACATCCTGTGGGAGGGACGGGAGCTGGTCAAGCATCGCTACCTCGTTCACGGCCAACCTGCGGACGGCGAAGACGACGAAGTAGGCCGGCTGTTCGACGAAGAACCGATGGGGCCGTTCCGGTGCTGTGGCTGTACGTTGATCTTCTACTCGGAAGCGGAACTGATTGAGCACAGGCAGTTGCAGCACGCGACCGTCGAGTCTGTGGCGACGTCGTTTCAGTTCCAGTGTGAGCACTGCCATCGCGTGTTTGACAAACTGGCGTTGTTCCGGGAGCATCAGGACAAGTTCCGGAATTTGCTGTACCGGTGCAAGATCGCCGACTGCAACTTCCGCTCCGAGAAGCGCCTCACCATCAAGGAGCACGTTTCGCCCTTCGTCAGCCACAACCGCGTTCCACCGCCGGCCAACATTAAGCTCTTTCAGTGTTGCGTCGATGGTTGCTTTTTCGACGACGCCTCCTACTGGACCGTAACGAAACACGTGGTCGCATCCCATCCGGAGGTTCGAGCCGCCAACGCTGGCCAGTACCAAGGTTCCAAGTTCAGCTGCCAGGCGTGCGGTATGGGATTTGAGGTGAAGACCGCTCGGGATTACCACGTGAGACGTCGCCGTGACCAGCAGCAGATGGCGTGTGACCAGTGTCCGCGGGTTTTCGGGGGGAAAATTGCCCTTTCGGCGCACAAGATTCGCTACCATGGGAATGCCGCTCGGAAGGCCAACGAGCGGTCGATTTGCAACATTTGTGGCAAGCAGGTTTCGGTGTACAACATGAGGGCCCACTTGGACGTTCACAACGACGTCCGACGGTGGCGTTGCACGGAATGTCCGGCGGCTTTCAACTACAAAACGCTGCTCCAGAAGCATGCCTTTAGCCACAGTGGCTTGAATACGGCGGTTTGTCGGTACGGGTGTGGCAAAGCTTATCGCCAGACTACGGACCGGAATCGGCACGAAAAGTTGGTCCACCAGAGCGATCAACCGTTGCCTTACGCGTGTACCGAGTGCGACGCGTCGTTTGTGCGGGATCGGGACTTGCGGATTCATTCGCGGAAGCACACCGGGTTGAAGCTGTTTCCGTGCGAGCGGTGCGGGGCCAGTTTCGATCTGCTGCGAGAGATTGAGAGCCACCGGGAGGAGTGCGTTGGAGAGCAGCTGGAACCGGATATGGAATACGTTGAGGAGTATGTAGTTGCTGATTAG
Protein Sequence: MEDLCRICRSAEVDELISVSCTVASQNRTVGEMIIAVMGLRFSLTQYDRMHRVPGQLCDRCLARLDRAYAIWKRCRFASGLARCKKGEEDGYFRCRICASGDADELISVTYVCKAWNVQIVTMVYELTAMRYKEGDGLPAYVCAECLKSLGVAYEFRRDALESAKAFEGASIDRYPWQAMQFQVDQPERLVVDLASEAQLDMKGGVYCSVCRAVIAAEELEKTCAGCMLEFSNYDAIVGKIANYGKREIKTEKGMDDGPAYESVDEVEVDEQSKAIEDDLSEFVQFKQEDSPLESSDEAYLPKTIKPLQKTNFHIENTVESVCCVMGCVWTGSQGELLWHRKHLHSDLAKLKSESQLMCRYCDRSFPSLGQLNKHCDRKRSIFKCLFNECTFTAKNMGGIVLHYAKHGSDKPAIGPPVIEAHQAEKHIATEHITEYACCVTDCHQTGTMDQIQSHYNRIHPDGMECRNGSYYCQHCERTFPDTDTLRHHFQRESTMYKCTIDGCCLSSKVKQILINHCTGPHQKVFKIKPVNTLRPKVTPRPDLKCFKVVGCVDDCIDVLSRKGEWCCTCHKLFASEDYLRQHRDTTHPVQPPSMFEDQHPFLCMQCNAGFSDANALTEHVAKNSQQNHYYCRGCKYILWEGRELVKHRYLVHGQPADGEDDEVGRLFDEEPMGPFRCCGCTLIFYSEAELIEHRQLQHATVESVATSFQFQCEHCHRVFDKLALFREHQDKFRNLLYRCKIADCNFRSEKRLTIKEHVSPFVSHNRVPPPANIKLFQCCVDGCFFDDASYWTVTKHVVASHPEVRAANAGQYQGSKFSCQACGMGFEVKTARDYHVRRRRDQQQMACDQCPRVFGGKIALSAHKIRYHGNAARKANERSICNICGKQVSVYNMRAHLDVHNDVRRWRCTECPAAFNYKTLLQKHAFSHSGLNTAVCRYGCGKAYRQTTDRNRHEKLVHQSDQPLPYACTECDASFVRDRDLRIHSRKHTGLKLFPCERCGASFDLLREIESHREECVGEQLEPDMEYVEEYVVAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402319;
90% Identity: iTF_00402319;
80% Identity: -