Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:57440484-57443134[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.47 14 6.8 0.1 2 23 222 244 221 244 0.95

2 13 0.02 0.6 11.2 2.9 1 23 272 295 272 295 0.91

3 13 0.001 0.032 15.2 0.5 1 23 303 325 303 325 0.98

4 13 0.0017 0.051 14.6 3.2 2 23 334 355 333 356 0.94

5 13 0.47 15 6.8 0.9 2 23 423 445 422 445 0.94

6 13 4.1 1.3e+02 3.9 1.3 6 23 455 472 455 472 0.96

7 13 0.012 0.37 11.8 0.5 1 23 478 501 478 501 0.96

8 13 0.074 2.3 9.4 0.8 1 23 509 531 509 531 0.97

9 13 0.005 0.15 13.0 1.1 1 23 539 562 539 562 0.95

10 13 0.31 9.5 7.4 0.1 2 23 569 590 568 590 0.94

11 13 0.0023 0.07 14.1 0.8 2 23 628 650 627 650 0.93

12 13 0.13 3.9 8.6 0.5 1 23 656 678 656 678 0.92

13 13 0.00052 0.016 16.2 3.4 1 23 684 707 684 707 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.47	14	6.8	0.1	2	23	222	244	221	244	0.95
2	13	0.02	0.6	11.2	2.9	1	23	272	295	272	295	0.91
3	13	0.001	0.032	15.2	0.5	1	23	303	325	303	325	0.98
4	13	0.0017	0.051	14.6	3.2	2	23	334	355	333	356	0.94
5	13	0.47	15	6.8	0.9	2	23	423	445	422	445	0.94
6	13	4.1	1.3e+02	3.9	1.3	6	23	455	472	455	472	0.96
7	13	0.012	0.37	11.8	0.5	1	23	478	501	478	501	0.96
8	13	0.074	2.3	9.4	0.8	1	23	509	531	509	531	0.97
9	13	0.005	0.15	13.0	1.1	1	23	539	562	539	562	0.95
10	13	0.31	9.5	7.4	0.1	2	23	569	590	568	590	0.94
11	13	0.0023	0.07	14.1	0.8	2	23	628	650	627	650	0.93
12	13	0.13	3.9	8.6	0.5	1	23	656	678	656	678	0.92
13	13	0.00052	0.016	16.2	3.4	1	23	684	707	684	707	0.97

Sequence Information

Coding Sequence: atgcAAACGGAACTTTCCGACTGCTTCACCTGCTGCCGAAGGACGGACACCTTCCTGCGAATCTGCGACGAGTCCAACACGGAGAATGTGGACCAGATTTTGGCtcgacacttttggttcaaGAGAAGTGACTACGAGCAGTCGGTGTTGTGCACCAGCTGCTGGGAAAAGATTGACGAATTTCACAAGTTTTACTGCGAAGTGGCCAACACGCACCGGGCGGATGTTTTGTTGCAAGGCGACCAAGTGATTCAGGTGAAGGAGGAGGAAATCGACGAAGAATCGGATGAGATATCGGCCGAGGAGGATACTCTTGAGGAACCATCATCGACGCGAGGTCGCAAGCGAAAGAAATCTCCATTGGAGGATGAAGAATTTGAAGCGCCGGTTGACGTGAAACTAGAGGAGGTTCCAGAAGAGTTTGACTCGGAGCAGATCGACGTTGAGCAGCCAAAGCTGGAAGTTGGACTTGGAGATGAGCAGAGCAGTAGCGACAGCGATGAGGAAACCGATGAAGAGGAAGACGACTCAGGTTCGGAATCGTCGCGACCGATAGCGGCACGGAAACGCAAGGCCAGCCAGGCTCGTCGTCGGGGACAGCAAGCCAAAGGAAGTTATTCGGCCGAGAAGGAATCGTTGATTCGGAAGCACTTCCCAAGGTTGCCGTGCGATCAGTGCCCGGAACAGTGGCCTAACTTCAAGCAACTGACGAAGCACGCCCGAAGAGAGCACGACTCACTGCCGACCGTAGTCTGTTGCAAGCAGTCGTATCAGAAACAGATTTTCCTGTTTTATCACCTTTTGAAGCATAAATTTTACTGCAAAGAGTGTGACCGATGCTACAAGACCGTGGACAGTTTTGCCATGCACAACATGCTGAACCACACGCCGGAGGAGGAGAAGAGATTCCGGTGCCATCTGTGCGAGACGGCCTTCGTGTCGGAACCGCTGCTGACTAGTCATCTCAACTGGCACGCGACTGTCGAGCCGAAGAATATCGTTTGTCAAAAGTGTAACAAGTTCTTCTCCAACACAAGAATGCTCGAGGAGCACACAACAACTCATCATCCTGAGTCGCTTGCGCCAGACGGCGTAGGATATCCAGCAAATGTTGACGGAACGGCGTTCTTCGAGCAACAATCGACTCTGGACCACCCGGCGGACAACACAACGGTCAAAAAGTCCCACGAGGGCAAACAGAACCGTCGCAAAACCCCGCAAGATCACGCCCGGGAGGACGAGCTGATTCGCAAGTACTGCGCGCTAAATTGTGAACAGTGCGACTACACGGCGGAAACGTTTAACCAGCTGGAGCTGCACTACAAGCACGCGCACGACGAACGCGGAGGTTACGCCACGTGCTGTGCGCGAAAGTTCACCAAAAAGAGCCGCCTGTACGAGCACGTTTGTGTGCACGAAAACCCGCAACACTTCAAGTGCGCCATCTGCGCGAAAACCTTCCTCAACAGCTTTGGCTTGTCGAACCACATGATGTGGAAGCATACGCCGGACTCGGAGAAGCCGTTCCGGTGTGATGTGTGCGGCAGTCGGTTTTGGAAGGATTATTTACTGAAGCAGCACATGGAGTACCATCTAGCGTTGGAGGAGAAGAAGTTCGCGTGTAAAGAGTGCAATCGATTCTTCGGAACAAACCTGCTTCTAAAATCCCACGAGCAATCCACGCACGGACTCAGCGCCAGCTGGGTGTGCGACGTCTGCGCTAAGGGGTTCGCCATGAAGTCGGCGCTCGAATTTCACCGCCAACAGCACTCCCAGGAGGGCCGGGCCGCGCTAAAGGCCCAGTGCGAACACTGCAAAATATGGCTCAAGAACATCAAGAGTCTGCGCAGCCACGTCAAGCGGTGCAAGTCCGAACCGGTTCCGTGTGACGTGTGCGGAAAGGAGTGCTCGAACGCCATGTCGCTGCGCAGCCATAAGAAGTTTGTCCACACGAACGCGACCACGTACTCGTGCTCGTTTTGCGCGAAACCGTTCAAACGGCTGCTGCGGCTTAAGGAACACGAAGCTGGACACACCGGCGAGCTGCTGTACAAATGCGAGTATTGTCCTCGGACTTGCAATTCCAGCTCGAATATGTACACCCACAAGAAGGTGGCGCATCCGGAGCAGTGGGCCGAGAAGATGTCTCAGCGGCACCAGCGGTAG
Protein Sequence: MQTELSDCFTCCRRTDTFLRICDESNTENVDQILARHFWFKRSDYEQSVLCTSCWEKIDEFHKFYCEVANTHRADVLLQGDQVIQVKEEEIDEESDEISAEEDTLEEPSSTRGRKRKKSPLEDEEFEAPVDVKLEEVPEEFDSEQIDVEQPKLEVGLGDEQSSSDSDEETDEEEDDSGSESSRPIAARKRKASQARRRGQQAKGSYSAEKESLIRKHFPRLPCDQCPEQWPNFKQLTKHARREHDSLPTVVCCKQSYQKQIFLFYHLLKHKFYCKECDRCYKTVDSFAMHNMLNHTPEEEKRFRCHLCETAFVSEPLLTSHLNWHATVEPKNIVCQKCNKFFSNTRMLEEHTTTHHPESLAPDGVGYPANVDGTAFFEQQSTLDHPADNTTVKKSHEGKQNRRKTPQDHAREDELIRKYCALNCEQCDYTAETFNQLELHYKHAHDERGGYATCCARKFTKKSRLYEHVCVHENPQHFKCAICAKTFLNSFGLSNHMMWKHTPDSEKPFRCDVCGSRFWKDYLLKQHMEYHLALEEKKFACKECNRFFGTNLLLKSHEQSTHGLSASWVCDVCAKGFAMKSALEFHRQQHSQEGRAALKAQCEHCKIWLKNIKSLRSHVKRCKSEPVPCDVCGKECSNAMSLRSHKKFVHTNATTYSCSFCAKPFKRLLRLKEHEAGHTGELLYKCEYCPRTCNSSSNMYTHKKVAHPEQWAEKMSQRHQR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402235;
90% Identity: iTF_00402235;
80% Identity: -