Cpip010659.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:181085757-181109779[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0098 0.3 12.1 0.2 1 23 190 212 190 212 0.97 2 8 8.2 2.5e+02 2.9 0.3 1 19 218 238 218 241 0.86 3 8 0.015 0.47 11.5 0.1 2 23 248 269 247 269 0.91 4 8 1.5e-06 4.5e-05 24.2 2.2 2 23 366 387 365 387 0.98 5 8 0.00037 0.011 16.6 0.1 1 23 422 444 422 444 0.97 6 8 0.00019 0.0059 17.5 3.6 2 23 450 471 449 471 0.97 7 8 3.1e-05 0.00095 20.0 0.4 1 23 477 499 477 499 0.98 8 8 0.00017 0.0053 17.7 0.8 1 21 505 525 505 526 0.94
Sequence Information
- Coding Sequence
- ATGGATTCCGACGAATCAGAACTCTGCTTGGAATCGTTCGCACCGTCACCGCAGCCAGATGATATCGAACCGAAACCAGCTTCACCATCCCCGGATCCACTGGACATCAAGGAAGAACCGATAGAGTTCGAACCCAGCCCCCAGTTCCATGTGGCCGCTCCCGATCCGCTGCAGATTCAGGGCTGTCTGTTCTGCTTCCGCGAACTGGCCAACGGACTCGGCGCCGAAGATCCGTCGCTGCCCAAAAAGATCGAGTTCGTGCTGGTGGCCAAGTTCAACTTCCGAAAGGCGCCCTACAAGGTCCCGTGCTGCACCAGCTGCGTGAAGATGTTCAACCTGTTCTACACGTTCAAGCGAAGCTGCCTGACGGCACTGGTCCGGCAGGATGAGCAGCAAAAGGCGAAGGTTTTGGAACCGATCGAGCTGGAAGCGGCAAAAAAGAAACCTGCTGCCGTGCGGGAAAAGGAACCGGAAGCGCTCGCTGAACTTCAACAGTTGCTGCCGGAAGTGACGCTCGTGAAGGTAGCGAAGCCGACGGTGCAACCCAAGAAGCCATCGGTGGCCGTTTTCAATTGTTCGATATGTCCAGCGAACTTCATCAACAAAAACGAATATGGCTATCACATGAACGGGCACAAAGacATAAATCCCTTCAAATGTGGGATCACCACTTGCCAGCAAGCGTTTCCCAGTCCAAAGGCGTGCACTCAGCATGAAGCCATGTGCGCATCAACACCCAAAACTTGCAAAATCTGTTCGTTGGAGTTTCCGACGGCAGCTGAACTTGAAGCTCACAATACTGCCCACATTCCTTCGGTTTGCCCGCGATGTAACGGGATGTTTGCGCTAGCTAAGGACTGCCAGAACCACATGACGGTTTGTCAGAGCGTAGAAAACGATCCTCAGTCAGACACCAGCAGCCAACAATCCAAGAAACCGCACTCCGAGAATAACCCCGAAGGGTCCGAATCCTCCGACCAGGATGAAGCCTCCACCGGTGCGCGTTCCTGCCGCAACTGCGGTCACAAATTCCCACTGGCCGGCGATATTTTGTTCCACCACCAACGCAAGTGTGGAGCGCTGCGGAAGCGTGTCAAGTGCCCACGCTGCGATAAGCATTTTACCCGGAAAGGAACGCTGGAGGCGCACCTCCGGCGACACGACGGCATACGTCCCTTCCAGTGTGGCAAGCCCGGCTGCGCGAAAACTTTCTTCAACCAGGGGGCGTGCGCCAACCACGAGGAAGGCTGCGGAACGCTGGGATTCGTTTGTGACGTGTGCGGAGCTACACTTTCGACGCAAGGTTCGCTCAAGCTGCACCGGGACAAGCACGAGGAACCCAAGATGCAGTGCAATCAGTGCGAGAAGCGGTTCCATGACAAGCGGAGCCTCCTGAAGCACATGTCGGTGCACTCGGACGAGCGCAAGTACGAGTGCAAAGTGTGCGGCAAGCGGTTCAAATCGGGCGAAGCTAACCGCGTCCATCAGCGGATTCATACCCATGAGAAGCCGTACGCATGTCCGGAGTGTGACCAGCGGTTCACGTACAACTGCTCGCTGAAGGCGCACCTGGAGAAGAAGGCGTGCCTGGTGCGATGA
- Protein Sequence
- MDSDESELCLESFAPSPQPDDIEPKPASPSPDPLDIKEEPIEFEPSPQFHVAAPDPLQIQGCLFCFRELANGLGAEDPSLPKKIEFVLVAKFNFRKAPYKVPCCTSCVKMFNLFYTFKRSCLTALVRQDEQQKAKVLEPIELEAAKKKPAAVREKEPEALAELQQLLPEVTLVKVAKPTVQPKKPSVAVFNCSICPANFINKNEYGYHMNGHKDINPFKCGITTCQQAFPSPKACTQHEAMCASTPKTCKICSLEFPTAAELEAHNTAHIPSVCPRCNGMFALAKDCQNHMTVCQSVENDPQSDTSSQQSKKPHSENNPEGSESSDQDEASTGARSCRNCGHKFPLAGDILFHHQRKCGALRKRVKCPRCDKHFTRKGTLEAHLRRHDGIRPFQCGKPGCAKTFFNQGACANHEEGCGTLGFVCDVCGATLSTQGSLKLHRDKHEEPKMQCNQCEKRFHDKRSLLKHMSVHSDERKYECKVCGKRFKSGEANRVHQRIHTHEKPYACPECDQRFTYNCSLKAHLEKKACLVR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00402156;
- 90% Identity
- iTF_00402156;
- 80% Identity
- -