Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:14483307-14489883[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.5 1.1e+02 4.1 6.2 1 20 198 217 198 221 0.89
2 15 0.093 2.9 9.1 1.4 1 23 260 282 260 282 0.97
3 15 5.9 1.8e+02 3.4 0.1 2 20 384 402 383 404 0.88
4 15 0.0058 0.18 12.8 0.7 1 22 411 432 411 436 0.93
5 15 0.77 24 6.2 1.8 2 19 524 541 523 546 0.90
6 15 0.57 18 6.6 0.4 1 21 559 579 559 580 0.94
7 15 0.78 24 6.1 0.4 1 23 587 610 587 610 0.94
8 15 0.031 0.95 10.6 0.7 3 19 677 693 676 696 0.93
9 15 0.37 11 7.2 1.5 2 23 706 727 705 727 0.96
10 15 7.2e-05 0.0022 18.9 0.9 1 23 733 755 733 755 0.98
11 15 2.2e-06 6.8e-05 23.6 0.6 1 23 761 783 761 783 0.98
12 15 0.14 4.4 8.5 1.2 2 23 790 811 789 811 0.97
13 15 0.00025 0.0077 17.1 1.8 1 23 817 840 817 840 0.93
14 15 0.00056 0.017 16.0 2.1 1 23 846 868 846 868 0.98
15 15 5.9e-06 0.00018 22.3 0.8 1 23 874 896 874 896 0.98

Sequence Information

Coding Sequence
ATGCCACCCCCGATGGAGAACCTGTGTCGAATTTGCGCCCGCAGCGAAGAGGACCGGCACGCGCCGCTGGTGTGCGTCTTCGGAACGACCATCGAGTTGGACCTGCGTCCCAAGAGTAGCGGTGGCGGCCAGTTGTGGTCGGAGGAAGGCGGCATCCTAGTTCAGACGGTCGCCCAAGCCATGGCCAGCTGCTTGGAGGTCGAGATTAAACACAGTGACCAGCTTCCGCAGCGGATCTGCGCGGAGTGTTTGGCCAAGCTGCGGGAATCGTGGGCGTTGAAGGAGATGTGCAAGGTTAGCGAGAAGCAGCTGCGTCGAATGTTGAACGAGGCCACCAGCGAGGAGGTCAAACGGGAAGATCCGGTGGAAGATGACGACTTTGGTCAGGACGTCTGCTTCGTCGAGGACGATGCGTACGAAGACGAAAAGGTGTTAGAGGAGCTGGTCGAGTTGCTGTCACCTCCCAGGAGGATCAATCCGGAAGATCCGCTCCATTCGGAGCTCGGTTGGCACATGTCGGATCTTCCCAAGGGAAAGTTCCTAACCAGACCTGGAGATGCCGCCAACTGGGACCGGGTTGAGGTCAAAGACTTCCGCTGCTGTGGATGTTACAAGTTTTTCGATTCCAAGGCGGAAATGGTGAAGCACTGCAAGCAGGAACACAAGGAAGAACCAGCCGGGAGGAACAAACGGTACGAGTGCTGCGTCTGCTTGAAACTGTTTGCCTCGACGGATGCGCTCAGCTTTCATGAAAAATTGGCCCGTTCGAGGCTCCTGTTCCACTGCAAACAGTGCGATGTGCTGTCGCCGAGCAAGCGCCAGTTGATGGCCCATTTGAAGTTGCACGCCCAAGGCAAGCTGGACATGGCGCCTGAGACGGTGGCCTCGCCGGTGAAGAAAGAGGAGAGGCCACTCACGCTGGCGAAGAAACCGGAGAAATCGTCGTTGGTGGAACAGAAGACGGTTGTGATAGTTGAGCCGCCTCCGGCGGAGAAATGTCGCGAGGTGAAGAACTTTGTCACGTTTGACTATTACGCCTTTGACGGGTTCTGCTGCTGCGATTGTTGGACGTACTGTGAAACGAAACGGGAGATGAAGCGGCACGGTGAGAAAGAGCACTTTGGGAACCGGGGATTCGAGGAGGACCAGACGTGCTTCGCTTGTTGGAGATCCTTCGCGGACAAGTCCATTTTCGACGCGCACATGGCCCTGCTCGCCACCAAACACCTCTACTACTGCAAACCCTGCCGGCTGCCGTTCCGAACGTCGGACCAGCTGCAGCAGCACCAACAGACCAGCGGCCTGCACGAGGGCTTCATCGAGCTGGAGATGATCGACATCAAGGAGGAGGTGGAAGCGGAACCTCCGTTTGGCGCCGGTTCGTTGGAAGTGGAAGATGTCGATGGCGATGACGACGCGGATTACGATCCGGACGAGGGCGGTTCTAAGAAGAGGGATTTCGTGGAACCGAATGGTCGGAGGCTGTACGCACCGCCGGGGAAAGACAAGCGGAACGATAAAGATGTGGTGGAGGCGTCGGTGGTGGCGATTTCGAACCAGGATGCGGTCCGGTGTTGCGGATGTTACCGGACGTTTATTACGGAGGAGGAGCTGGCGGATCATTGCGCGAGGGAGCATTTGCCGGTGCGGGTGTTTGGCGATAAGCAGTTGCCGTACGAGTGTGAACGGTGCTTTAGGAGGTTCAATTTGGGGACGGCGTTGACGATTCATCAGCAGTTTGCGAGGACGGTTCGAGAGTATGCGTGCAAGTTGTGCGCGGAGAAGTTTAGCTTCCAGACACCGTTTTTGCTGCACGTTAGCAGGGTTCATGAGTTTTTCCACGTTCAGAAGAGGGTAAAACCGGGAGCAAAGGCGGCTGTTCCTGCGGAGAACAACAAGTTCCACTGCTGTTTTATGTTGTGCAAGCAAGCTTACGACGAGTACGGGGATTTGCTCTGCCACGTGGACGAAGTTCATGGACTCAAGAGGAACCAGTTCAAGGACTATCGCGACACGGATGAGAATTGCTGCGAGATATGCTTCCGAAGCTTCAACAACTACGGAGCTTTGCTGCGCCACGCCTCCCAACAGCGCAGGATTCGCCAGACCGTGTGCACCTGCAGCACCTGCGGCTACCAGGCCAAATCGACCGCGGGACTCCGTGACCACGAGAACAAACATCTCGGCCTGCGACCGTACGAATGTGAGCTATGCCAGAAGACGTTCAGCTCGAAAACAATCCTCAAGAACCACATGCTGGTCCACGTGTCGGATCGTCCGTTTAGCTGTGAAATCTGCGGCAAAACGTTCGCCCGCAAGCGCAACTGGAAGGACCACGCGATGACGCACCAGGAGAGCAAACCGTGGGAGTGCGAAGTGTGCAAGATGCAGTTCCGCATCGAGACGCAATTTATGACCCACAAGAAACGCCACACGGGAGTGCGTCCGTATAAATGCACCTACTGCGAGAAGGTGTTTTCCCACGCCACCGACCGGAAGCGGCACGAAATGGCGGCCCACACGGGGGAGAAGCCGCACCAGTGCTCGTTCTGTTCGCTGGCGTTCATTCGGAAGAGGCAACTCATCATCCACGAACGAACACACACCGGTGAAAAGCCGTTCGAGTGTCAGTACTGTTCGCAGGCGTTCATTCAGCAAAGCTATCTGACAAGGCATTTGGCAACGCACAAGATGTAG
Protein Sequence
MPPPMENLCRICARSEEDRHAPLVCVFGTTIELDLRPKSSGGGQLWSEEGGILVQTVAQAMASCLEVEIKHSDQLPQRICAECLAKLRESWALKEMCKVSEKQLRRMLNEATSEEVKREDPVEDDDFGQDVCFVEDDAYEDEKVLEELVELLSPPRRINPEDPLHSELGWHMSDLPKGKFLTRPGDAANWDRVEVKDFRCCGCYKFFDSKAEMVKHCKQEHKEEPAGRNKRYECCVCLKLFASTDALSFHEKLARSRLLFHCKQCDVLSPSKRQLMAHLKLHAQGKLDMAPETVASPVKKEERPLTLAKKPEKSSLVEQKTVVIVEPPPAEKCREVKNFVTFDYYAFDGFCCCDCWTYCETKREMKRHGEKEHFGNRGFEEDQTCFACWRSFADKSIFDAHMALLATKHLYYCKPCRLPFRTSDQLQQHQQTSGLHEGFIELEMIDIKEEVEAEPPFGAGSLEVEDVDGDDDADYDPDEGGSKKRDFVEPNGRRLYAPPGKDKRNDKDVVEASVVAISNQDAVRCCGCYRTFITEEELADHCAREHLPVRVFGDKQLPYECERCFRRFNLGTALTIHQQFARTVREYACKLCAEKFSFQTPFLLHVSRVHEFFHVQKRVKPGAKAAVPAENNKFHCCFMLCKQAYDEYGDLLCHVDEVHGLKRNQFKDYRDTDENCCEICFRSFNNYGALLRHASQQRRIRQTVCTCSTCGYQAKSTAGLRDHENKHLGLRPYECELCQKTFSSKTILKNHMLVHVSDRPFSCEICGKTFARKRNWKDHAMTHQESKPWECEVCKMQFRIETQFMTHKKRHTGVRPYKCTYCEKVFSHATDRKRHEMAAHTGEKPHQCSFCSLAFIRKRQLIIHERTHTGEKPFECQYCSQAFIQQSYLTRHLATHKM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00402090;
90% Identity
iTF_00402090;
80% Identity
-