Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:104213623-104216481[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00084 0.026 15.5 1.4 2 23 325 346 324 346 0.97

2 11 1.1e-05 0.00033 21.5 1.1 2 23 353 374 352 374 0.97

3 11 0.0031 0.096 13.7 0.4 1 23 384 406 384 406 0.97

4 11 0.27 8.2 7.6 0.5 1 15 493 504 493 513 0.76

5 11 0.0067 0.21 12.7 3.2 3 23 527 548 525 548 0.95

6 11 0.015 0.46 11.5 1.1 2 23 554 575 553 575 0.91

7 11 0.00011 0.0035 18.2 0.5 1 23 580 602 580 602 0.92

8 11 0.0047 0.14 13.1 0.1 2 23 611 633 610 633 0.97

9 11 0.00065 0.02 15.8 1.6 3 20 641 658 639 660 0.93

10 11 0.00014 0.0044 17.9 0.7 1 23 671 693 671 693 0.99

11 11 0.0016 0.049 14.6 2.6 1 23 699 722 699 722 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00084	0.026	15.5	1.4	2	23	325	346	324	346	0.97
2	11	1.1e-05	0.00033	21.5	1.1	2	23	353	374	352	374	0.97
3	11	0.0031	0.096	13.7	0.4	1	23	384	406	384	406	0.97
4	11	0.27	8.2	7.6	0.5	1	15	493	504	493	513	0.76
5	11	0.0067	0.21	12.7	3.2	3	23	527	548	525	548	0.95
6	11	0.015	0.46	11.5	1.1	2	23	554	575	553	575	0.91
7	11	0.00011	0.0035	18.2	0.5	1	23	580	602	580	602	0.92
8	11	0.0047	0.14	13.1	0.1	2	23	611	633	610	633	0.97
9	11	0.00065	0.02	15.8	1.6	3	20	641	658	639	660	0.93
10	11	0.00014	0.0044	17.9	0.7	1	23	671	693	671	693	0.99
11	11	0.0016	0.049	14.6	2.6	1	23	699	722	699	722	0.98

Sequence Information

Coding Sequence: ATGGTGAAAACTGAAAGCTGTGCGTTGTGTTTCGCGACAAAGTCAAAATGGTTTTTGGACATATTCTGCGACGAAAATCAGACCGTGAATATTTCCGCGATCATCTCGAAGCATCTTTGGTTCGATTTGAGGCGCTCGGACCAGTGTTATGTTTGTGCCGAATGTTGGAAGAATGTTTACGATTTCCATCTGTTTTACTGCAAGCTTGAGAAGTTACACTTGGAGACGGGCGATGCCGACTCCAAGACGATCCCGATCACGAACCAACCGGCATTCGAGTTTCATCCGATTGATGAGGTCAAGCTTGAACCCCCGGATGAGGATGAATTCGGAGAACCGTCACGGGTTGCTGACACGAGTGGAACCACAAACGTTGCCGATTCGTCGGCAGGTGAGATTGGGGAACCGTCCGTGAAGTTCCGTTCATCTCCGATACCCACGACACGAGTGAAGGCAAGCGATGATGAGCCGACAACATTCAAGACGGAACTGACCGACTCGGATCCGGAAGAAATTGATCCGGATGACTTTCTGGCTGCCGATttcgacgacgacaacgatgACGATGACTACGAGGAAGAGGTGAAAGAGGTAAAGAAACCGGTTCTGACGAAGAATGGAAAGCGCCGTGGAAGGCCACCGAAGAATGCCGCCCTCAAGCAGGAACCGCTGGATGATTTGTCCGCTTTGTTCGCATCGGATGGTGGAGAGTGCTCGAAGGATGTGGTCAAGAAGCGGAAATATAAGCGTAGGATGAAAATTAAGAAGGAAAGCGACAGCGATGACGATTCCgattacgacgacgacgacggagatAGGCGAAAATCGGGAGGAAAACGGTCCCGAGATGAACGTCTGTTTTCGTACATCACGGAGTTTGTGTGCTATCTATGTCCGGATCGGATCGAGTTTGATCGCTTCCATCACGCCAATCTTCACTATAAGGATTTGCACGGTGAACCGGCGTATTTAAAGTGTCCCAAATGTGACCGCAAATGCTTCACGCCTGGGGGCTTTGTAAATCACATGGAAACGCATGAAGATCCGGAGAAGAACAAATGTAAGATTTGCGGCAAAGTCACCGATCAGAAGATCACTCTCAAGAAGCACATGCGTGCTCACCGGGCAGAAATGGAGGAGAAATTCCCGTTCGCCTGTACGCAGTGTCCTCGGCGGTTCGAGTTGGAGCGGGCTCTGACCAAGCACGAGAGATTGCACGGCCGAAAGTTGCACATCGTGAGACGTGAAAAGGGACGCGATGACGAGCTTATTGCATTCTACAAGAAAATCTCGTGCGATATTTGCGACCAGGAGAAGAACGACGGCGTCGAGTATCAAAACTTCTGGGATCTGAAAGTTCACATGTCGGGCGAGCACAACAAGACGCCGTATCTCAAGTGTCCCCTCTGCTCGAAGAAGAACGTGTGTCGCCAGCAGTTGATGGTTCACGTCGACGTGCACGAGAATCCGGATAATTACCGatGCGACATTTGCGGAGAAGTTTTCCAATTTCTTGAGAGACACAAAGTCAAAGCACATGGTCGAGAGCAGGCCGAAAAGAGCGAGAAGAATTATGGTTGTGAGCACTGCGGAAAAATGTTCCGATGTGAGCAGAACCTCAAGAACCACATTGACCGCGTGCACGGCGTTAAGGACGTTACGTGTGACATCTGCCACAAGTCATTCAGCAAGAAGGCCATCAGCGCCCATCGAAAGTCGGCACACACCGATGAGATGTTCATGTGCGAACAGTGTCCCAAAATGTTCAAGACTCGCTCGGGCCTTGAATCGCACAAGGGCGAACACGATGTCGAGCTCCGGAAACCGGTAAAATGTGAACTTTGTGGAAAAGAGATGCGTAGAGGGGCCAGTTTGGCCAAGCACATGAAGGTCATTCATTCCCAGGAGGATCCGGTGAATTGTAATATGTGCGGCAAGCAGTTCCGCACCAAGTTCCACATGATTCGCCACCGGACAAATACCTGCGCGGCCACGATCGACTCGCGACCGTTCAAATGCGAAGTATGCGGAAAAGGCTTTTCCATGAGATTGACGATGACCGAACACATGACCACGCATACCAGGACGAGTTTGTATCAGTGTGCATTCTGTTTCAAAACATTTGGATACATTTCCAACCTATACAAGCACCGCAAGAAGGCCCACCCGGAAGAATGGCAGGAGGTTCAGGCCCGGCCTGAACAGGGCATCGCGACCGTCATTGAGATGAGAAATTAA
Protein Sequence: MVKTESCALCFATKSKWFLDIFCDENQTVNISAIISKHLWFDLRRSDQCYVCAECWKNVYDFHLFYCKLEKLHLETGDADSKTIPITNQPAFEFHPIDEVKLEPPDEDEFGEPSRVADTSGTTNVADSSAGEIGEPSVKFRSSPIPTTRVKASDDEPTTFKTELTDSDPEEIDPDDFLAADFDDDNDDDDYEEEVKEVKKPVLTKNGKRRGRPPKNAALKQEPLDDLSALFASDGGECSKDVVKKRKYKRRMKIKKESDSDDDSDYDDDDGDRRKSGGKRSRDERLFSYITEFVCYLCPDRIEFDRFHHANLHYKDLHGEPAYLKCPKCDRKCFTPGGFVNHMETHEDPEKNKCKICGKVTDQKITLKKHMRAHRAEMEEKFPFACTQCPRRFELERALTKHERLHGRKLHIVRREKGRDDELIAFYKKISCDICDQEKNDGVEYQNFWDLKVHMSGEHNKTPYLKCPLCSKKNVCRQQLMVHVDVHENPDNYRCDICGEVFQFLERHKVKAHGREQAEKSEKNYGCEHCGKMFRCEQNLKNHIDRVHGVKDVTCDICHKSFSKKAISAHRKSAHTDEMFMCEQCPKMFKTRSGLESHKGEHDVELRKPVKCELCGKEMRRGASLAKHMKVIHSQEDPVNCNMCGKQFRTKFHMIRHRTNTCAATIDSRPFKCEVCGKGFSMRLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPEEWQEVQARPEQGIATVIEMRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402100;
90% Identity: iTF_00402100;
80% Identity: -