Cpip013860.3
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:49026280-49031594[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00055 0.017 16.1 1.1 2 23 318 339 317 339 0.97 2 10 0.0009 0.028 15.4 0.8 1 23 347 371 347 371 0.97 3 10 2.6 81 4.5 0.2 3 23 376 397 374 397 0.94 4 10 0.00013 0.004 18.1 3.5 2 23 403 425 402 425 0.95 5 10 0.0032 0.098 13.7 1.0 1 23 431 453 431 453 0.96 6 10 3.5e-05 0.0011 19.8 0.7 1 23 459 482 459 482 0.97 7 10 0.0022 0.068 14.2 3.1 2 23 488 510 487 510 0.96 8 10 0.036 1.1 10.3 0.1 1 23 516 538 516 538 0.97 9 10 5.4 1.7e+02 3.5 0.0 2 21 545 564 544 565 0.92 10 10 0.31 9.4 7.4 0.4 2 22 620 640 620 640 0.92
Sequence Information
- Coding Sequence
- ATGTCCATCTTCAAGCTGCGAGCGTACCCCTTCGTGTGCCGGCTGTGCCTGAAGCCGGAACAGCACCGGAAGATGACGTCGCTGGACACCGAGGACGAGTGCTTCGAGGGGGGAACGCTGGAAGACTTTCTGGCCACGATCACGTTCCAGGTTGAGGAGGAAAAGCGCCATCTCTTCCCACGGTCGGTCTGCCCCCAGTGCAAGGAACTGCTCCAAATGTTTGGCCGCTTTCGTACCAAAGTCCGCCACCTGCACCTGTTTATGAACGCACTGGTTGAGCTGCGAGACTTCAACACGGCACCGATTAAGGAGCTATGCAGGACGAAACTAGGCATGGTCCGGACGATGCTCGCCGAGTTGGACCTGTGCCACACGGTTGGCTTCTTTGCGCAAGATTTGATTGATGAATTTCCCCACTGCAAAATTGCTAAACTTCCGGCCACTATGGTGCAGAGTTGTCCTGGTGAGATTGTTCAAATCAAAGTCGAAGAAGATGAACCGCTAGGCGTTGAAGTGTTTAATGCGTTGGAAAAACCAGAGGAGGATGATATTTTCGCTGAGGAATGCTCACCGGAAGAATTAGCTGAGCTGACTAAAGAAATAGTTGCTGATGAAAATGTGACATCCGAGGAAATTATGCAAGATGATGTTGAACAGGAGCAGGAGCCTGACCAAGTTGATGTTGAACAGGAGCAGGAACCTGACCCTGATGTAAGGTGGGAGTGTTTTGATGATAGCGACGAAGAAGTAGAGTTTCCCAACAAACCAACAAAGAGAGAGTTGAGAGCGTTGAAAGCGTCAGAAAGGAAAAAAGCAATGGAAAAGGGCGACATGTGGGACCTTCTCAACGAAAACGAACCAGCAGTGGAACTCACACTGGAAAGAGTGGGCGATTTGGATGCGGCACTAGCCAACAGAAAGTACGGTACTGCGAAAGCAAAAGAGCCGCTGCAGTGTCCCAAGTGTCCGTATACAACCATCTTCAAGTCGAATTTTTACTCACATCAGCTGACCCATCTGAGGCGTGAAAACAAGACTTACCCGTGCAAGGAGCCTGATTGTACGAAAACGTGCGCGTCACTACGGCTGTTACAATCCCACATGGAATCACACTCATCGGTTATCTGCGAGACCTGCGGCGAAAGGATGCCTACCACTACCAGATTGAAGGAACATGTCCTACGTTATCACAGCAACGAGCGCATCACCTGCGAGTACTGCCAGCGAACTTTCAAGACAAAATGTGATCTGCGAAACCATGTCAAAAATATACACCTGTCGGATAGCGTGTTCAAGTGTGAGACGTGTGGGATGGAGTTTCGTCGAAAAACTATTCTTAAATCGCACGAAGCCAGGCATCGCGACGTTTACAACTTTCCGTGCCAGCAGTGTGATAAAAAGTTCAAGATAAAAAACTTACTGCAAAAGCACATTGCTACAGTACATAACGAGGCGTCGCTTGAGTGCGAACACTGTTTCAAGATGTTCCACCGAAGAGCCTTGCTGATGGACCACATCGAGACCAAGCATAAGattcaGATGCGCTTCGTCTGTGATGTGTGCGTGGCCATATTCTACACCCAGGACGATCTGGGGACCCACAAGGCTCGTCacgaaaatcccaaaaatctcgAGTGTGGCCTATGTTTGATAGTGTTTCCCGCGCAGGAACAAATGCAAGATCATTTGTGCATCACGTACAGGGACGATTACACCTGCTGCAAGCGAGATTGGCGACAGCATCAGCAATACAACCGGCACATGTTCCTCAAGCATGGCGTCAAGATAAACGCCCGGGTTAAGCCGGATCCGCACCTTTTGCAGGGCCAAGTTCGTGCCAAGAGAAAACGAGTTGAAAGTTGCTCCAAATGTGAGGCCGTCTTCGCTACAAGAACACTGAAAAAGCAGCACCAGGAAACGTGTACTGCAGAATTGAATACCTAG
- Protein Sequence
- MSIFKLRAYPFVCRLCLKPEQHRKMTSLDTEDECFEGGTLEDFLATITFQVEEEKRHLFPRSVCPQCKELLQMFGRFRTKVRHLHLFMNALVELRDFNTAPIKELCRTKLGMVRTMLAELDLCHTVGFFAQDLIDEFPHCKIAKLPATMVQSCPGEIVQIKVEEDEPLGVEVFNALEKPEEDDIFAEECSPEELAELTKEIVADENVTSEEIMQDDVEQEQEPDQVDVEQEQEPDPDVRWECFDDSDEEVEFPNKPTKRELRALKASERKKAMEKGDMWDLLNENEPAVELTLERVGDLDAALANRKYGTAKAKEPLQCPKCPYTTIFKSNFYSHQLTHLRRENKTYPCKEPDCTKTCASLRLLQSHMESHSSVICETCGERMPTTTRLKEHVLRYHSNERITCEYCQRTFKTKCDLRNHVKNIHLSDSVFKCETCGMEFRRKTILKSHEARHRDVYNFPCQQCDKKFKIKNLLQKHIATVHNEASLECEHCFKMFHRRALLMDHIETKHKIQMRFVCDVCVAIFYTQDDLGTHKARHENPKNLECGLCLIVFPAQEQMQDHLCITYRDDYTCCKRDWRQHQQYNRHMFLKHGVKINARVKPDPHLLQGQVRAKRKRVESCSKCEAVFATRTLKKQHQETCTAELNT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00402142;
- 90% Identity
- iTF_00402142;
- 80% Identity
- -