Cpip010498.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:176653928-176658765[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.081 2.5 9.3 0.4 2 19 251 268 250 271 0.91 2 12 0.017 0.52 11.4 0.9 2 23 282 303 281 303 0.97 3 12 0.3 9.1 7.5 0.1 2 23 338 360 338 360 0.96 4 12 9.1e-06 0.00028 21.7 1.7 1 23 366 389 366 389 0.97 5 12 0.005 0.15 13.0 0.1 3 23 399 420 398 420 0.95 6 12 0.00044 0.013 16.4 1.0 2 23 432 454 432 454 0.93 7 12 0.006 0.18 12.8 0.5 1 20 680 699 680 701 0.93 8 12 0.082 2.5 9.2 0.7 3 23 711 731 709 731 0.92 9 12 0.039 1.2 10.2 1.2 2 22 739 760 738 760 0.92 10 12 0.034 1 10.4 2.3 1 23 796 819 796 819 0.95 11 12 0.00092 0.028 15.4 0.0 2 23 827 849 826 849 0.96 12 12 0.0054 0.17 12.9 1.2 1 23 855 878 855 878 0.95
Sequence Information
- Coding Sequence
- ATGGACCAGACGGAACAGCAGTTTAGCCTAACTCTATCGTCGGAGCCGTTCTGCACGTTCTGTCTGCGGGCAAGCCCGCCAAACGTGCAGCTGTACAAGTACATCACGGGTGGGTTCGTCGAGCTGCGGCTGTCGTTTGAGTCGATACTCGGGTACGAGTTCCACCTGGACAGCTTTGCCATCTGTAAGCCGTGCTGGAGCTTAGCACAACTGTTCCAGGACTTCCGAACACGGTGTCAGAGGGCCAACGGGTTGCTGGAGCGGATAGGTCATGGGCTGAGGGGGGAGGGAGATGACGGTTGGTTTGGGGAGCAGAACCTTGCGACCATCGAGGGCATCCAGAAGGTGATTCAGGACCAGTTGGCACAGATTGAGAGGGTTGATGCAAAGGGGGAAGATGTTCGGATGATTAAGACAGAACCGATTGACGTCGAGCAGTGCTCGAGTGATGAGCTGAAGCCAACAGAATCTAGTCAACAGTTGAGTCAGGACAAGAACAAGGACGTTCCTGCACCAGCATTCCATATGGTAGAAATTAAGGTTGAACATCACGATGAAGTGGACTCTGAAGAGAGTGACGAAGCGTCTAAATCTGCAGCGGAACCAAAGGACGAGGTACCAGAGAAAATGGAACAAACAACTCAACCAAGTCCAAATTCGTCAGTTGAATCAGCTAAAGAGGACAAAGAAATGGAAGTTGAACCAGCGGAAGAAGGCAACCCAGAATGTAATGAACCCTCAGAGCTCGTGGAATGTGATAAATGCGGCAGAAAGTTCGACAAATTGAAAAGCATGAAGCTGCACTCTATGAACTGTGATGGAACATTACCGACCCGACTTTTAACTTGCGAGCTGTGTAAAGCCTCATTTCTCGACCGCCGTCTTTTGAACACGCACATGAACAAACATGAAGGCAAAACTCCATTCCCATGTCGCAAGCTCTGCAAAGCGTCCTTCATTTCCGCCCAGATCCGCAACCGGCACGAGCTCACCTGCTGCAACGATCGCCGCAAGTGCACGCTGTGCGAGGAAGTCCTGCCCGACCAGATGCGCCTGTTTGCGCACTACAGGCTCGCGCATCCGGGAGAGCTCCGCTATCCGTGCCCGACCTGCCACAAACGCTTCAAACGCAGAGACGCCCTCGCGTCCCACGAGCGCAGACTCCACTCCGAAAGTCGCCCGAAAACCGAAGCCTGCCAAATCTGCGGCAAGATGTTCGCCGAGCTGAACGATCTCAAGGGGCACGTCAAGCTGATGCACGAGAATCCGGGCGGAACGCGCGCCAAGCCGGCTCAGTGTGAAGTGTGCGGTAAGCGGTGCAGCAAGCAGAACTCGCTGAACATGCACATGGCCGCGGCACATCCGGAGCAGACGACGCATGCAAACCTGGAAGCGTATAGGCGGAGGTGTGTGCTGAATATGGAGCGGAAGCGGAGGAAGAAGTTGGTGGATTCAATTCCCCAGATAATGAACGCCCCATCATTCTGCGCGTTCTGTCTCCGGACAAGAATTTCGCACATGAAGCTGCACAAACAAGTCGCCGGATGTTCGGACGAGCAGCGGCAGTGCTTCGCGCTGATACTCGGATACGACTTCCAGCTGGAGAGCTTTGCCGTCTGCCGACCCTGCTGGAAGCTGATGGAGCTGCTGCAGGACTTCCGGCTGCGCTGCTTGAAAGCAAACAACCTGGTGGAGAGGATCAGCCGAGGGATGCTTCCGGGAATATACGAGGACGATGGTTGGTTTTCGGATAATACTTGGGCCAAAATCGAAAGCTTCCGGGCCGTTATCCAACAGCAGATCGTGCAGATTGAGAAGATGGAGGCGACTGCGGGAGAATCCGATTGCAATGGTGAATCAACGGAAGAGTATGATGAAATAAAGATTGAACCGGTGGAAATTCAAGACGAAGTCGTCGAATCAGATCTGGAATGTGAGGAAACTCTTCAACGCAATAGCGTGATGGAGTTCGAATCCAGTGTTGACAGCAATCTAACTTGTGATGAACCCGCAATAGAAAAGAATTCAACTGGTTTATTCAAATGCAAGAAATGTGACCAGAGTTTCATAACTAACGAAAGGGTAATGCAGCATTTGCTGAACTGTGATGGAACTTTTAATCCCTTAGCTTGCAATTTGTGTGAAGCGACGTTTACAGAACACAAACAACTGATAACTCACTTGGTATTTCATTCTAGAGCCCAAAATGTTGTCAAATGCCGAATTAAATGTGCCAAAACATTTAGTTCAAAATCTAATCGCTTGAGACATGAGAAAACTTGCGACAAAGTTTATCAAAAGTGTCCTCTGTGCGAAGCGCATCTGGATCTCGGACAAGAACCCCTGCACGAGCACTATAGTCTTGTACATCCAGCAGAACTGAAACATCCATGCACGAAATGTGACAAACGCTTTCTAAACCAAGAACAAGTCAAATCTCACGAAAAAGTAACTCACGCCGAGGGGCGCATCAACGTGCCCTGTCCGGAGTGCGGAATCATGTTTGCCGAGGCCAAAGATCTGATCGTACACACCAAGCGAATCCACAGCGAACTGTGGCTCTTTCAGTGTGACCAGTGTGGGAAACGACACCGTGATAAGCAGTCGCTAGTGACGCACATGGCCGAAGATCACGCGAAGCTGGCACCGGAAACAGCGGCGACGCCAACTGTGGTCCGGATGTGTGAACGAAAAGCTAATCCGAAAAGGGCTGTGGATAAGGAATCGGGTGGTTCGAGTGCTTCAAAAGAGCCGCCGTTTAAGGGATTAAAGTTAAGATCTTTTCAAATCATTAGTCCGTGA
- Protein Sequence
- MDQTEQQFSLTLSSEPFCTFCLRASPPNVQLYKYITGGFVELRLSFESILGYEFHLDSFAICKPCWSLAQLFQDFRTRCQRANGLLERIGHGLRGEGDDGWFGEQNLATIEGIQKVIQDQLAQIERVDAKGEDVRMIKTEPIDVEQCSSDELKPTESSQQLSQDKNKDVPAPAFHMVEIKVEHHDEVDSEESDEASKSAAEPKDEVPEKMEQTTQPSPNSSVESAKEDKEMEVEPAEEGNPECNEPSELVECDKCGRKFDKLKSMKLHSMNCDGTLPTRLLTCELCKASFLDRRLLNTHMNKHEGKTPFPCRKLCKASFISAQIRNRHELTCCNDRRKCTLCEEVLPDQMRLFAHYRLAHPGELRYPCPTCHKRFKRRDALASHERRLHSESRPKTEACQICGKMFAELNDLKGHVKLMHENPGGTRAKPAQCEVCGKRCSKQNSLNMHMAAAHPEQTTHANLEAYRRRCVLNMERKRRKKLVDSIPQIMNAPSFCAFCLRTRISHMKLHKQVAGCSDEQRQCFALILGYDFQLESFAVCRPCWKLMELLQDFRLRCLKANNLVERISRGMLPGIYEDDGWFSDNTWAKIESFRAVIQQQIVQIEKMEATAGESDCNGESTEEYDEIKIEPVEIQDEVVESDLECEETLQRNSVMEFESSVDSNLTCDEPAIEKNSTGLFKCKKCDQSFITNERVMQHLLNCDGTFNPLACNLCEATFTEHKQLITHLVFHSRAQNVVKCRIKCAKTFSSKSNRLRHEKTCDKVYQKCPLCEAHLDLGQEPLHEHYSLVHPAELKHPCTKCDKRFLNQEQVKSHEKVTHAEGRINVPCPECGIMFAEAKDLIVHTKRIHSELWLFQCDQCGKRHRDKQSLVTHMAEDHAKLAPETAATPTVVRMCERKANPKRAVDKESGGSSASKEPPFKGLKLRSFQIISP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -