Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:99260889-99267559[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0021 0.065 14.2 0.4 2 23 281 303 280 303 0.96

2 8 0.0017 0.051 14.6 0.6 1 23 311 333 311 333 0.96

3 8 4.9e-05 0.0015 19.4 0.7 1 23 342 365 342 365 0.95

4 8 3.3e-06 0.0001 23.1 0.1 1 23 371 393 371 393 0.98

5 8 0.00069 0.021 15.8 2.5 1 23 399 421 399 421 0.96

6 8 0.00023 0.007 17.3 0.8 1 23 426 448 426 448 0.97

7 8 0.00012 0.0036 18.2 1.3 1 23 454 476 454 476 0.97

8 8 0.0076 0.23 12.5 3.3 1 23 482 505 482 505 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0021	0.065	14.2	0.4	2	23	281	303	280	303	0.96
2	8	0.0017	0.051	14.6	0.6	1	23	311	333	311	333	0.96
3	8	4.9e-05	0.0015	19.4	0.7	1	23	342	365	342	365	0.95
4	8	3.3e-06	0.0001	23.1	0.1	1	23	371	393	371	393	0.98
5	8	0.00069	0.021	15.8	2.5	1	23	399	421	399	421	0.96
6	8	0.00023	0.007	17.3	0.8	1	23	426	448	426	448	0.97
7	8	0.00012	0.0036	18.2	1.3	1	23	454	476	454	476	0.97
8	8	0.0076	0.23	12.5	3.3	1	23	482	505	482	505	0.97

Sequence Information

Coding Sequence: ATGCTCAGCAACTGGCGCAGCTGGTGCCGGCTGTGCGCCAACGAGTGCGCCGTCTACAAGCTGGAATCGCTGGACGAACTGAACGAAATCACGATGAGGCATTTCCACTTTTCGCTGCAGGAGCTGGCGGACGTGTGCAACTGCATCTGCGAGGAGTGCTACAACTTTGTCAACAAGCTGGAGCGGTTCAAGGAGCGCTGCCTGCAGACGAGCAAGATGCTGCTGGAATTTTGCGCCTCCTCCGCCAGCGATGACGCCGAGCTGCTGGACAGTGACATCCAGGATTTGCGGTTCCGGTTTTTGAGCGATTCCATTTTGGCGGCCGTCGAGGAGGCGGACTCGCAGGACGTGAAGGGCTTCACGGTGAGCAGCGTGGTGGAGGGGGCGGTGGATGGAGTGCAGGCGAGTAGTCTGGCTTCCGATCAGGAGGGGGGTGTGGACGCCGGGGAACTTACCGAGCCGGAGCTGGTCCAGCTGAAGATCGAGAAGGTGGCCAACAGGAAGAAGCGGAAATCTTCGGATCGGCTTGTTTCAAATCTGGACGAATCGGTCAAGGAGAGTGATAGCGTCCTGACGAGGTTGACGGTGGACGAGTTTGGCGAGTTCAAGGTGGACGATACGTTGATGTCCAACGAGCCGGAAGGGTTTGACGCGTACGACAACGATTACTTGGATGAAGAAAAGCCAGAGCTGGGAAGCGATCCCGACGAGGAAGAGTTGGACGAGGAGGaagaggaagaggaggaggaagaagagGACGAGGAACAGGAAGAACCGAAACCGGCCGTGTCAAAGCCTCGTTCGAAGGCGCGTTCCAAACCGGACCAGCAGCAGCGCGTTCGCTGCGAAGAGTGCGACAAGTCGTATGCTAGCAGGCAGATGTACGTGCTGCACTTGCAGTCCAAGCATCCGGACTCGCCCGAGTTGCGGTTCCAGTGCGGGATTTGTCCGAAGCGGTTCTCCTCCGAGAAGAAGACCAAACAGCACGAGGCGGTGCATCTGCCGAGCGACCAGAAGATGGTGCATCCGTGCAACtattgtgataaaaaGTTCAGCAAGCTGGTCAACGTGCAGGCCCACATCAAGGCGGTCCACATCGGCGAGCGGCCGTACGTTTGCGAAGAGTGCGGCAAGGCGTTCGGAACCAAGGGCGCCCTCAAGGAGCACCAAGTCACGCACAGCGACGAGAAGCCGTTCCAGTGCTCGCACTGTCCGAAAAAGTTCAAGAATCTGCCGCGCCTCAAAACCCACGAGGACATCCACACCGACACGCTGTACGTGTGCCCCCACTGCGGCCTCCAGCTCAACACCAAGCGAACGCTCAAGATGCACATGGTCGTGCACTCGGACCAGAAGAAATTCAAGTGCCAGTACTGTGGCAACGAGTACAAACGCTCCAAGGCGCTCAAGAACCACCTGATTCTGCACACCGGCCTCCGACCCTACCAGTGTCCATTCTGCGAGAAAACCTTCGCCAACGGGTCCAACTGTCGAAGTCACAAGAAGAAGGCCCACCCCAAGGAACTGGCCGCCCTCGAAGCATCCGGCGGTCAATCCCGCGCCACCAACATCCCCAAGCTGAACCAGCTGCAACCGAAGAGCGCGACCACCACCACCGACCAACCCGCAGACCCAGAAGAACCCTCCGCCATCCCGCTAACCCCCGAAGAGCAGCTGGTCCTAACGCGTGGCGTCCGCCTGGTCACCGCTTACTTCCACTCCACGCCCAGCGAACCACCTCCGCTGAACATCCTGTCAACGGGGGCGCAGACGACGTCAACCACCGGAATCAAGTCCGAGGCGGAGTGTCTGTCGGGGGCGGAGGGTGGCGATGCGGGAGTGGTGATCGCCCAGGTTGGGGAATCGATGCAGGAGCTGGTCGGACTGCCGCCGCTGCAGCTCATCTCGAGTGGCAATTTGTGA
Protein Sequence: MLSNWRSWCRLCANECAVYKLESLDELNEITMRHFHFSLQELADVCNCICEECYNFVNKLERFKERCLQTSKMLLEFCASSASDDAELLDSDIQDLRFRFLSDSILAAVEEADSQDVKGFTVSSVVEGAVDGVQASSLASDQEGGVDAGELTEPELVQLKIEKVANRKKRKSSDRLVSNLDESVKESDSVLTRLTVDEFGEFKVDDTLMSNEPEGFDAYDNDYLDEEKPELGSDPDEEELDEEEEEEEEEEEDEEQEEPKPAVSKPRSKARSKPDQQQRVRCEECDKSYASRQMYVLHLQSKHPDSPELRFQCGICPKRFSSEKKTKQHEAVHLPSDQKMVHPCNYCDKKFSKLVNVQAHIKAVHIGERPYVCEECGKAFGTKGALKEHQVTHSDEKPFQCSHCPKKFKNLPRLKTHEDIHTDTLYVCPHCGLQLNTKRTLKMHMVVHSDQKKFKCQYCGNEYKRSKALKNHLILHTGLRPYQCPFCEKTFANGSNCRSHKKKAHPKELAALEASGGQSRATNIPKLNQLQPKSATTTTDQPADPEEPSAIPLTPEEQLVLTRGVRLVTAYFHSTPSEPPPLNILSTGAQTTSTTGIKSEAECLSGAEGGDAGVVIAQVGESMQELVGLPPLQLISSGNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402063;
90% Identity: iTF_00402063;
80% Identity: -