Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:269231-281117[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 3.4e-05 0.001 19.9 1.5 1 23 447 469 447 469 0.98

2 7 1.8e-05 0.00055 20.8 1.9 1 23 475 497 475 497 0.98

3 7 0.22 6.6 7.9 1.9 2 23 763 784 762 784 0.97

4 7 4.3e-08 1.3e-06 29.0 1.5 1 23 790 812 790 812 0.98

5 7 0.0016 0.05 14.6 3.1 1 23 822 844 822 844 0.98

6 7 0.0067 0.2 12.7 2.1 2 23 1067 1088 1066 1088 0.97

7 7 6.5e-07 2e-05 25.3 1.4 1 23 1094 1116 1094 1116 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	3.4e-05	0.001	19.9	1.5	1	23	447	469	447	469	0.98
2	7	1.8e-05	0.00055	20.8	1.9	1	23	475	497	475	497	0.98
3	7	0.22	6.6	7.9	1.9	2	23	763	784	762	784	0.97
4	7	4.3e-08	1.3e-06	29.0	1.5	1	23	790	812	790	812	0.98
5	7	0.0016	0.05	14.6	3.1	1	23	822	844	822	844	0.98
6	7	0.0067	0.2	12.7	2.1	2	23	1067	1088	1066	1088	0.97
7	7	6.5e-07	2e-05	25.3	1.4	1	23	1094	1116	1094	1116	0.99

Sequence Information

Coding Sequence: ATGATTCAAGTCGACTCTGTTGGATACTCTAGAGTGAACGATAAATCCCAAGCTGATGAAGATATGAAGGAGAATGATAGTTGCGAGCAGGATAATTCAAGCGCAGCACCGTCGGTGAATTTACTAGTAAAAATGTCGGAAGAAATCGCAGAGAAAGATCGCAATAAGCAGGAGCATCTGAACGATAACCACCATAACCATCTTCCGGTCCGACATCATTTGCAGCACGATCGcagtgaaaatgttcaaaatgaggaAAATATGAGCGATGATGATGAAAACAACGACGATAACGGAAGCGGGGTTGGTCGAAATGAGATGGAAAACGACCACGGTAGCAAGAACGATCGAAGCTCCACGCCACACGGCAATTTGTCAGATGAACGACCGGAGGTTAATGCTGCGGCTGTGGCGATGGCAGCTTTGGCAGCGACGAAAAACTCCGCTGGAGGTTCTCCAACGCTACCGAACGAGTTCAATCCCGCTGCATTTTTCCCACAGCCAGGACAAATGTCGATTCAAGCCTTTCAGAATGCGATCGCTCAATTCACGGCAAATGCATTGGCCAACAACATGGACAATGATACAGTTGTGAAAAATTTAGCCATCCTGCAATCGGCACTTTTCACGCTGCAACAGCAACAGTTTCTGCAGTTTCAACTCATACAACATCTGCAGTCGCAACTGGTGAAGAAGCAGGTTACCAAGGAAGAACCATCGAACGATAGTAGTAATAGTTTAGTGTTTCatcataacaataacaataatctTAGTAAGAGAAATGAGCCTCAAGATTTGCGAAAGCAGGAACGGTTAGAAGAAGATGAAGAAGTCGAGGAAGAGGGCATTGAGGATGCCTACAGTAAAAGCTATCAGATGGCGAATATAATGGCCGTTGCAGCTGCTGCCAGTGCGGAAAATCGACCAGTGATACATCCCGTTCCCGAAGAAGAACTAAGGAAACCAAAAGTTTCTGAGCCGTACGTTGAAAAACGGCCAATTGCAGAACCTTCGATCAGTTTGCCTCCGTCGACGGTGGCGGCCAGTGCAAGTTCAAGCCTTCCCACTTCCATCTATTCACATAGTGGAAGGAGCGAAAAGGATGAAATTCTACCATATCAAGACTCGAATTTCTCGTCACTAGCCGCGAATATTATAACGGATCACGCGCCATCGATCCTGGGTGAACCAAATTCACTTGCAATGCTGGAAAAGAAAGCCCAAGAAGTGCTCAATTCAGCTTCGCAAGGCATTCTGTCCAATAATCTGCTTGATGAGCTCGCCTTTGCAAACGATAAATCATCTCCAAATGGTCGAAACGATGCAGCCCTTTTCAAGCACCGATGTCGGTATTGTGGCAAAATTTTCGGATCAGACTCTTCGTTACAAATTCACATCCGATCACACACCGGCGAGAGACCGTACAAGTGCAATGTTTGCGGGAGTCGCTTCACTACCAAGGGCAACCTAAAGGTTCACTTTCAGCGGCACTCTGACAAGTACCCGCACATACCGATGAACCCAAATCCCGTGCCGGAACACTTGGACAAATACTTTCCTCCGTTGATTCCACAGGAAGCTCTCAaagaacagcagcagcagcagcaacaacaacaacaacagcaacagcaaggACCACCACCTCCTTCTTCAATCCCACCCCCTGGTCCACCAGGTCCGTTTCCAGGCATGGAATCGCGAGGTTTCCCGCCAAGGGGATTTTTCCCAGACTTTTACCTGCCGAGGCCTCCTCTGGACATGTTCACGAATCCGCTGAACGAGCCAGCTCGGAATCCGGTTGATTTGTCCCAAGTGAGGAAACCGGAACCACCACGGGAACCTACACCAGAGATGCGGCTCTCGCCGGAAATCATCATCCATGAGCAACCACCCCAAATAAAGCAGGAACCGATGGAAGAGTCGTTGGACCTTTCGGACAAATCCTCGAAAGTTGTTCAAAGAGAAGAAGAGAAAGAAGAAATGGAACAGGACAAAGAGGATAATACGACTCTAAACAACAGCACCAGTGAAAAAGAGTTTCCCTTAAAGTTGAAGAACAACTCCGTGGAAAACCTTGCGACGGTACCCTCGGTATCACCTCCTTCGAGCTCATCGTCAGGGTCACTGTACCAAGACACGGTGTTGGATCCGTCGTTTTACTCTGCACATCTGCCTCGCCCAGACAGCAACGATAGCTCGTGGGaaaactttattgaaatttcgtCAGAAACATCGAAATTGCAAGAGCTTGTCGATAATATCGATAGCAAAACAACGGAACCCAACCAGTGTTTGGTTTGTAAGAAAGTTTTATCTTGCCGAAGTGCACTTCAAATGCATTACCGAGTTCACACCGGTGAGCGTCCATTTCGGTGCAAAATTTGCGGTCGATCGTTTACGACCAAGGGCAATTTGAAAACGCATATGAGTGTTCATAGGATAAAACCTCCGATGAGGACCCTCCACCAGTGCCCGGTGTGCCACCAAAAATTCTCCAACATCTTCGTCCTGCAACAGCACATCCGATTGCACACGGGAGAAATGACGGACCTTACTCCGGATCAAATAAAGGCGGCTGAAATCAAAGAGTACGAAGGGCCCGATATGCGGTTGAATCCGTTTGGAGTGCGGTTGAATGAATTTCCTCCCCAGCAGCACAATCAGAACAAACGCAATTTAGAACATTCAGACGAGGAAAACGAGCACGAGCCAGCGGAAGAAAAATCTCACAAGGTTCCTGTGAATGAGAAAATTAAGGTTAAAACCGGACTTACGTCACCAGCAATTGAAAATCAGGTGGAAGATTTGCGTGCCGTAAATTTACAACGATTGTCGGTTCGATCGTTGCCAAATGAGGAATTTACCCGTGACACGGCTTCGGCCAGCCCAAACTCGACGGACGCCAAAAGGTTACGATCGTCCAGTCCGATCGGGTCGGTATCGTCGGTGATGTCCAACCGGTCTCCCATGTCCACACCACCCACATCCGGCGGTGAACAGATAGGAGCAGGAGCCGCGAGTAGAGCCGCCGTCGCCGCTGCCGCAGCAGCTGCTTTTCCTTACGGACCTCCGTTCCTTGGAATGCCCCAGTTTCCACCGTTCATCAATCGGCCGCCCTTTTTGGGCAATGTTCCGATAGTGCCACCGGGAGCAAACATGCCTCCGTTTGGATTGTTCGGCGTACGTGGAAACACAACAACTTGTAATATTTGCTTTAAAACTTTCGCATGTAATTCCGCGCTCGAAATTCATTATCGAAGCCATACGAAGGAGCGCCCATTCAAATGCACAATTTGCGATCGAGGATTCTCTaccaagGGAAATATGAAGCAGCACATGCTCACACACAAGATCCGTGATATGTTTGGCAGCTCGGGTGGCAATTCCGGGGATGAGTCACGCACACAGACTCCGCCGCAGGACTCCAGTAACGCTGGTTCTGCTGGTGGTGGGCCGAACAGCATGGCCACCAGCAACCGGTTCTCACAGTCGTACTCGCCGGCGCCCATGGACTCCTCGGCCGATGATTACTCCTCTTCGGGGAGACGGAAACGGGAACGTTCCCAATCTGGCAGCTATGACGGTTCCGGCAGAACTTCAGCGGTTCTGGTGAAACAGGAGAGAGAATCTACAATCGATGAAAATGGCTCCAACAGTCTGCACTCGAATGCGTCGGAAAACACCTCCAACAACAATTATCAGGAGTTTATCAACAAAGATGCCGACATCAAAAATTGGTGCCAAAAGCTGAAAGAGATGCCAGAGAATATCGCAGCAAGTTGA
Protein Sequence: MIQVDSVGYSRVNDKSQADEDMKENDSCEQDNSSAAPSVNLLVKMSEEIAEKDRNKQEHLNDNHHNHLPVRHHLQHDRSENVQNEENMSDDDENNDDNGSGVGRNEMENDHGSKNDRSSTPHGNLSDERPEVNAAAVAMAALAATKNSAGGSPTLPNEFNPAAFFPQPGQMSIQAFQNAIAQFTANALANNMDNDTVVKNLAILQSALFTLQQQQFLQFQLIQHLQSQLVKKQVTKEEPSNDSSNSLVFHHNNNNNLSKRNEPQDLRKQERLEEDEEVEEEGIEDAYSKSYQMANIMAVAAAASAENRPVIHPVPEEELRKPKVSEPYVEKRPIAEPSISLPPSTVAASASSSLPTSIYSHSGRSEKDEILPYQDSNFSSLAANIITDHAPSILGEPNSLAMLEKKAQEVLNSASQGILSNNLLDELAFANDKSSPNGRNDAALFKHRCRYCGKIFGSDSSLQIHIRSHTGERPYKCNVCGSRFTTKGNLKVHFQRHSDKYPHIPMNPNPVPEHLDKYFPPLIPQEALKEQQQQQQQQQQQQQQGPPPPSSIPPPGPPGPFPGMESRGFPPRGFFPDFYLPRPPLDMFTNPLNEPARNPVDLSQVRKPEPPREPTPEMRLSPEIIIHEQPPQIKQEPMEESLDLSDKSSKVVQREEEKEEMEQDKEDNTTLNNSTSEKEFPLKLKNNSVENLATVPSVSPPSSSSSGSLYQDTVLDPSFYSAHLPRPDSNDSSWENFIEISSETSKLQELVDNIDSKTTEPNQCLVCKKVLSCRSALQMHYRVHTGERPFRCKICGRSFTTKGNLKTHMSVHRIKPPMRTLHQCPVCHQKFSNIFVLQQHIRLHTGEMTDLTPDQIKAAEIKEYEGPDMRLNPFGVRLNEFPPQQHNQNKRNLEHSDEENEHEPAEEKSHKVPVNEKIKVKTGLTSPAIENQVEDLRAVNLQRLSVRSLPNEEFTRDTASASPNSTDAKRLRSSSPIGSVSSVMSNRSPMSTPPTSGGEQIGAGAASRAAVAAAAAAAFPYGPPFLGMPQFPPFINRPPFLGNVPIVPPGANMPPFGLFGVRGNTTTCNICFKTFACNSALEIHYRSHTKERPFKCTICDRGFSTKGNMKQHMLTHKIRDMFGSSGGNSGDESRTQTPPQDSSNAGSAGGGPNSMATSNRFSQSYSPAPMDSSADDYSSSGRRKRERSQSGSYDGSGRTSAVLVKQERESTIDENGSNSLHSNASENTSNNNYQEFINKDADIKNWCQKLKEMPENIAAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01462507;
90% Identity: -
80% Identity: -