Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:57431516-57457931[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.2 2.8e+02 2.8 0.1 9 23 187 202 174 202 0.85

2 14 0.054 1.7 9.8 0.4 6 23 211 228 211 228 0.99

3 14 0.0022 0.066 14.2 2.7 3 23 238 259 237 259 0.95

4 14 0.00054 0.016 16.1 0.1 1 23 267 289 267 289 0.97

5 14 0.24 7.4 7.8 3.9 1 23 297 319 297 320 0.92

6 14 0.63 19 6.4 0.2 3 23 360 381 358 381 0.95

7 14 3.3e-05 0.001 19.9 0.5 1 20 414 433 414 433 0.96

8 14 0.0015 0.047 14.7 0.1 1 23 445 467 445 467 0.98

9 14 0.00058 0.018 16.0 0.6 1 23 475 498 475 498 0.96

10 14 0.0003 0.0092 16.9 0.2 2 23 505 526 504 526 0.97

11 14 5.2 1.6e+02 3.6 1.5 2 21 537 556 537 557 0.93

12 14 0.83 25 6.1 1.6 2 23 566 588 566 588 0.95

13 14 0.0019 0.059 14.3 0.8 1 23 594 616 594 616 0.94

14 14 0.0012 0.038 15.0 3.3 1 23 622 645 622 645 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.2	2.8e+02	2.8	0.1	9	23	187	202	174	202	0.85
2	14	0.054	1.7	9.8	0.4	6	23	211	228	211	228	0.99
3	14	0.0022	0.066	14.2	2.7	3	23	238	259	237	259	0.95
4	14	0.00054	0.016	16.1	0.1	1	23	267	289	267	289	0.97
5	14	0.24	7.4	7.8	3.9	1	23	297	319	297	320	0.92
6	14	0.63	19	6.4	0.2	3	23	360	381	358	381	0.95
7	14	3.3e-05	0.001	19.9	0.5	1	20	414	433	414	433	0.96
8	14	0.0015	0.047	14.7	0.1	1	23	445	467	445	467	0.98
9	14	0.00058	0.018	16.0	0.6	1	23	475	498	475	498	0.96
10	14	0.0003	0.0092	16.9	0.2	2	23	505	526	504	526	0.97
11	14	5.2	1.6e+02	3.6	1.5	2	21	537	556	537	557	0.93
12	14	0.83	25	6.1	1.6	2	23	566	588	566	588	0.95
13	14	0.0019	0.059	14.3	0.8	1	23	594	616	594	616	0.94
14	14	0.0012	0.038	15.0	3.3	1	23	622	645	622	645	0.98

Sequence Information

Coding Sequence: ATGGCGTCGGATTCGCTCAAGAGCTGCCTGACCTGCTGCCGGCAGACGGAAAACTTCCTGCGCATCACCGAGAGCGACGAGGCGAGCGAGGAAAACGTCGAAGCTGTTTTCGCCACACACTTTTGGTTTACCAAGGACGAGTGCCATGGTCGCATCGTTTGTACCAGCTGTTGGGAGAAAATTGacgattttcataaattttattgcGACGTGAAGAAGGTACACCATCCGTTGATCAAACAGGAGCAGGACGATGGGTTGGAGGAGCCGGTTTTGGAGAGCAAAGAGGACGTAAAAGGAGCTGATGATCGTCTACTGTATGCTGAGGTTATATGTAAGCTAGAGGAGGAAAACAAATCGGAAATCGCCAGCGAGCCTGAAGCTAACAACCCAAACGATGACGAGTCAACCAGTTCAAGTGAATCGGAATCGAACTCAACGTCCTCGGACTCTGATTCGGACGTTCCACCGGTGAGGCGAACCAAGCGTAAACGGAGAACAAGGACAAACATTGAACTGAACTGCAGCTTGTGCGCGGATGAAGGAACGTACTGCGAGCCGTTCTACACGTGGTACAAGTTGAATGTGCACTTTAAGCAAACCCATGGGCAGAATGGATTCATGTACTGCTGCAGCAAACGATTCGTTACGAAGCCGCTCTATTTGAAGCACATTAAAAGTCATGGACGATCAGCGCTGGAGCAAAAGCACTGCTTGGAGTGTAAGTGTTCGTTCAAAGACGAGAGTGGACTGGCCCGGCACATGATCATTTTCCATACCCCAGAGGAGGAGAAGCAGTTCAAGTGTGATCGCTGCGAGAAAGCATTCCCCGAAGAGGATCTGCTCAAAAGTCACATAAGCTGGCACGATGAGGTAGAGCAGCTGAATCATCACTGTGCGATTTGTAACCGGTACTTTACTGGGGCAGGACTCTTGAGAACTCACAATGAAAATCATCATTCAACGGTGCCAGCGGAAACGGCGACGGAGGCCATGTCTGCAGACAGGCGTAAACGAAGTACGCCGGAAGATATCGCTAAACAAGACGAACTTATCAGCCAGTATGTCACAATGATCTGCTCAAAGTGTGACTTTGTTGGTGCAAACTTTAAAGAACTTTCGTCACACGCTAAAAGTGCGCATAATATGCCCACTTACTCGGTGATTTGTTGTGAACGAAAGTTCAGCAAACGGTTCCGCTTGTACGAGCACTGTCTGAAACATTTGAACCCGGACCACTTCAAGTGCGAACTTTGCGATAAAACGTTCACCGACAGTGACGGTCTGCAAAGTCACCGCTGGTTCATCCACACGCCCGTCTCGGAGCGACCTTTCAAGTGCGATGTATGCGGCGATGCTTACGTTAAAGAGTACTTGCTAAAGGCTCACATGGATCGCCATCTGGACAAGGAACGCAAGACGCACACCTGTGACTCGTGCGGTGTAACGTACACCACGCTGCCTCAGTTGAAGGCCCACCAGCAGAACGTCCACGGTGCGATGAGCGATTGGGTTTGCGacgtgtgcgccaaaggattcgcCCACCGTGCCCTGCTTGAGCGACACCGCCTTACGCACACAGAAGAAGGCCAGAGAAGTCTAAAGGAACAGTGTGAAAAGTGCCACAAATGGCTCATCAACAGGACGTCGTACTTGCGTCACCGGAAGCTCTGCGGAAACAGTACCGGACCGGCCAAGTGCGATCTGTGCGAGCACGTTTCGGTTAACGCTCACGCGTTGTCCGTGCACAAAAAGCTTAACCATACGGATCGTCCCAAGTACGCTTGCCAGTACTGTGGCAAGGAGTTTAAAAAACAGTTGCGATTGAAGGAACACGAAGCAAACCACGCCGGAATCGTGCTGTACAAGTGTCCGTTCTGTCCGCGCGAGTGCAACTCCAGCTCGAATATGTACACCCATAAGAAAACGGCCCACGCGGAACAGTGGGCGGCCGTCGTGGCAGCGAAGCACAGCAAATGA
Protein Sequence: MASDSLKSCLTCCRQTENFLRITESDEASEENVEAVFATHFWFTKDECHGRIVCTSCWEKIDDFHKFYCDVKKVHHPLIKQEQDDGLEEPVLESKEDVKGADDRLLYAEVICKLEEENKSEIASEPEANNPNDDESTSSSESESNSTSSDSDSDVPPVRRTKRKRRTRTNIELNCSLCADEGTYCEPFYTWYKLNVHFKQTHGQNGFMYCCSKRFVTKPLYLKHIKSHGRSALEQKHCLECKCSFKDESGLARHMIIFHTPEEEKQFKCDRCEKAFPEEDLLKSHISWHDEVEQLNHHCAICNRYFTGAGLLRTHNENHHSTVPAETATEAMSADRRKRSTPEDIAKQDELISQYVTMICSKCDFVGANFKELSSHAKSAHNMPTYSVICCERKFSKRFRLYEHCLKHLNPDHFKCELCDKTFTDSDGLQSHRWFIHTPVSERPFKCDVCGDAYVKEYLLKAHMDRHLDKERKTHTCDSCGVTYTTLPQLKAHQQNVHGAMSDWVCDVCAKGFAHRALLERHRLTHTEEGQRSLKEQCEKCHKWLINRTSYLRHRKLCGNSTGPAKCDLCEHVSVNAHALSVHKKLNHTDRPKYACQYCGKEFKKQLRLKEHEANHAGIVLYKCPFCPRECNSSSNMYTHKKTAHAEQWAAVVAAKHSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402079;
90% Identity: iTF_00402079;
80% Identity: -