Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:15164263-15167079[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 2.8 85 4.4 0.1 6 23 264 282 264 282 0.89

2 13 0.00015 0.0045 17.9 0.9 2 21 293 312 292 313 0.94

3 13 4.7 1.4e+02 3.7 0.2 1 19 320 338 320 340 0.84

4 13 0.019 0.58 11.2 4.9 1 21 403 423 403 424 0.95

5 13 0.012 0.37 11.8 0.6 1 23 477 501 476 501 0.86

6 13 0.012 0.36 11.9 0.1 1 21 519 539 519 540 0.95

7 13 0.0029 0.09 13.8 1.1 3 23 548 569 546 569 0.93

8 13 0.00021 0.0064 17.4 1.3 1 23 581 604 581 604 0.97

9 13 0.0014 0.043 14.8 1.8 3 23 612 633 611 633 0.92

10 13 2.8e-05 0.00085 20.2 0.4 1 23 639 661 639 661 0.97

11 13 0.00073 0.022 15.7 0.4 1 23 666 689 666 689 0.93

12 13 7.2e-06 0.00022 22.0 1.9 2 23 696 717 696 717 0.98

13 13 0.64 20 6.4 0.0 1 23 723 748 723 748 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	2.8	85	4.4	0.1	6	23	264	282	264	282	0.89
2	13	0.00015	0.0045	17.9	0.9	2	21	293	312	292	313	0.94
3	13	4.7	1.4e+02	3.7	0.2	1	19	320	338	320	340	0.84
4	13	0.019	0.58	11.2	4.9	1	21	403	423	403	424	0.95
5	13	0.012	0.37	11.8	0.6	1	23	477	501	476	501	0.86
6	13	0.012	0.36	11.9	0.1	1	21	519	539	519	540	0.95
7	13	0.0029	0.09	13.8	1.1	3	23	548	569	546	569	0.93
8	13	0.00021	0.0064	17.4	1.3	1	23	581	604	581	604	0.97
9	13	0.0014	0.043	14.8	1.8	3	23	612	633	611	633	0.92
10	13	2.8e-05	0.00085	20.2	0.4	1	23	639	661	639	661	0.97
11	13	0.00073	0.022	15.7	0.4	1	23	666	689	666	689	0.93
12	13	7.2e-06	0.00022	22.0	1.9	2	23	696	717	696	717	0.98
13	13	0.64	20	6.4	0.0	1	23	723	748	723	748	0.90

Sequence Information

Coding Sequence: ATGTTCTTCGAAAACGAATCAGACCCGGAAGAGACGCCACCCTGTCGGCTCTGCTTGGAGACGGAAGTGGACGAGCTGATTTCCCTGTTCGCGCGCTGTTCCTCGCAGCAGAAGCTCGTGTCGGAAATGATCAGCGAGCTCACGAAGCTGTCCCAGTACGAGATGGGCGACATGTCGCAGTACATCTGCGGCCGCTGCCTAGAACAGCTGGATAAGGCGTGCACGTTTCGGAAGCGCTGCCGCGACACCAACCGATTCTTCACCGGGCAGCTGCTGCGGAACAGCTTGAAGAACGTGGACGGATGCTGTCGGCTGTGCGAGGACGACGAACCGGACGAGCTGATTTCGGTGTTTTGCATCTGCGAGGGCAAGCTGATTGCGGAGCTTATCGGACGAACGGTGGGCCTGAAGAAGCCGGTGGAAACGGACGGACTTCCGCAGCACATTTGCGGCCAGTGTTTGGATCAGCTGAGCTGTGCGGCCCAGCTGCGGGAGATGATTTTGGAGAACGATGCGCGGACGCGAGCCTCGCACGTCAAGGTCGAGGAAGATTCGATGAACGCCGAAGAGTTGTTCAACGTGGCCGAGGAGGGATGGTCCGTGCCGGGTGTGACTCCGAAGGTGCGGGTTCAACGCCCGAAGCCACAACCCCCGCCGGAGGAAGAAGTTGATCCGTTTATTTATCTGGACGTTCCGGGTGAGGAAGGGGAAAAATTGCAAGAGGCCTTTGAAACGGTGGCCGAGGGTGAGTTTTACGAACAACTGTTGTTTGGCGGACTTATTTGCTGCTGTGGAAAGCTGTTTGGAAGTGAGAAGGAGCTGCAGACACATCGTGGATTGATGCACGCGAAACAGGAAGTCGCGTGGAGTAGCATCAAGTGTAATGATTGCAAGAAGCGATTCAAGAGCAAGTGGGATTTGGACCGCCATCGTAACGAGCGTGAAAAGAAACAGTTCTATCGCTGTAAGATCTGTAATGTTCTTACGAAGGAGATGACAACGCTGCAGATTCACTTTGAATTTACTCGATTCCATCCGTGGTTGGAGCCGTCCGAGGAGGAACAAACGAAATTCGACAGCGTGGTAGACACCTTGTACGAGATTGATGGCCGATGCTGCGCTTGTGAGGGTGAGTTTGAGGACGCAGAAGCGTTGCTGGAACATGTCAAGGAGGCGCACTACGATGATCGGGATGATGTTCCGATGTTTCAGTGCACCATTTGCTACAGTTGCTTCTCGGACCGTAAAAGTCTTCACCAACATCAGCAAAGCTTCAGCGGTACGAGAACGTACCAGTGTCGTGCAGAGAATTGTACGTTTAAGACCGATCAGCGTGCGGCAATTCGTAAGCACGTGGAATCCGGACTGCACTGTGATCAAGCTGGTTTCCCCGCAAGATACGTCATCAAAGAACTTATTGAGGAATTCTTCTGCTGCATGCGCGATTGTAACGAGGTATTTCCGAGCAGGGAAGAACTGGAGCAGCACAGCTCGGTCGCTCATGAGGAGAAACGCACGGTCAACTATCACTTCAGCAAAGACGCAGACCCAGACTACGTTTGTGACCTGTGCAAGCGTCTCTTTCCATCAGCGGAGGCGTACAAACGCCACGCCCGTTCCATCATCGATCGCAAGGTCATGTGCACGGCGTGCAGCCAGAGATTTTCGACTCGCGAACAGCTGACCCGTCACGAAAAGTACTACCACCTGCCGGCCGACGAGAAGGAGCCCCAGGTCGTGCACCAGTGTCCGCACTGTCCAGCGACACTCCGCACGCCGGTCACTCTGCAGCAGCACATCAAGAGTCAGCACGAAGGCACCGCCGGCGAGCTGTGCAAAACGTGCGGCAAGATCTTCAACACGAAAACACTGCTCAAATCGCACGAAACCAACAGGCACATGAAGATCAAACCGTACCGCTGTAACCAATGTCCGATTAGCTTCGGCTCGAAGTTCCTGCTCCAGCGACACATGATTGGCCACACGGACCAGCGGTACCCGTGCAACTACTGCGGCAAAGAGTACCGCTATCCGAACGACACCAAACGGCACGAGCAGGCGGTCCACTTGAACGAAAAGCCCGAAAAGTGCGAGTACTGCGGCAAGTGCTTCATCCGGGCTCGCGATCTACGTCTGCACATTTCTTCGCACACGGGCGTGAAGCTGTTCCAGTGCATGGTGACGGGATGTGACTATTCGACCAACGTCGCCAAGCAGCTGGCCGCCCACGTCGATGAGCAGCACCAAATGGAGGTGAAGGAGGATTCGGATTAG
Protein Sequence: MFFENESDPEETPPCRLCLETEVDELISLFARCSSQQKLVSEMISELTKLSQYEMGDMSQYICGRCLEQLDKACTFRKRCRDTNRFFTGQLLRNSLKNVDGCCRLCEDDEPDELISVFCICEGKLIAELIGRTVGLKKPVETDGLPQHICGQCLDQLSCAAQLREMILENDARTRASHVKVEEDSMNAEELFNVAEEGWSVPGVTPKVRVQRPKPQPPPEEEVDPFIYLDVPGEEGEKLQEAFETVAEGEFYEQLLFGGLICCCGKLFGSEKELQTHRGLMHAKQEVAWSSIKCNDCKKRFKSKWDLDRHRNEREKKQFYRCKICNVLTKEMTTLQIHFEFTRFHPWLEPSEEEQTKFDSVVDTLYEIDGRCCACEGEFEDAEALLEHVKEAHYDDRDDVPMFQCTICYSCFSDRKSLHQHQQSFSGTRTYQCRAENCTFKTDQRAAIRKHVESGLHCDQAGFPARYVIKELIEEFFCCMRDCNEVFPSREELEQHSSVAHEEKRTVNYHFSKDADPDYVCDLCKRLFPSAEAYKRHARSIIDRKVMCTACSQRFSTREQLTRHEKYYHLPADEKEPQVVHQCPHCPATLRTPVTLQQHIKSQHEGTAGELCKTCGKIFNTKTLLKSHETNRHMKIKPYRCNQCPISFGSKFLLQRHMIGHTDQRYPCNYCGKEYRYPNDTKRHEQAVHLNEKPEKCEYCGKCFIRARDLRLHISSHTGVKLFQCMVTGCDYSTNVAKQLAAHVDEQHQMEVKEDSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401997;
90% Identity: iTF_00401997;
80% Identity: -