Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:111541271-111543845[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.57 17 6.6 1.4 1 23 281 303 281 303 0.97

2 12 0.061 1.9 9.6 0.7 1 19 307 325 307 328 0.94

3 12 1.3e-05 0.0004 21.2 1.5 1 23 332 355 332 355 0.97

4 12 8.9e-05 0.0027 18.6 0.3 2 21 368 387 368 388 0.94

5 12 0.0011 0.034 15.1 0.4 2 23 433 455 432 455 0.95

6 12 0.11 3.3 8.8 4.4 1 23 463 485 463 485 0.91

7 12 0.012 0.37 11.9 1.7 2 23 505 527 505 527 0.92

8 12 0.00029 0.009 16.9 4.0 1 23 534 557 534 557 0.94

9 12 0.0038 0.12 13.4 3.2 1 23 564 586 564 586 0.97

10 12 0.00027 0.0082 17.1 2.8 1 23 592 614 592 614 0.98

11 12 3e-05 0.00093 20.0 3.5 1 23 620 642 620 642 0.99

12 12 0.0045 0.14 13.2 0.3 6 23 653 671 648 671 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.57	17	6.6	1.4	1	23	281	303	281	303	0.97
2	12	0.061	1.9	9.6	0.7	1	19	307	325	307	328	0.94
3	12	1.3e-05	0.0004	21.2	1.5	1	23	332	355	332	355	0.97
4	12	8.9e-05	0.0027	18.6	0.3	2	21	368	387	368	388	0.94
5	12	0.0011	0.034	15.1	0.4	2	23	433	455	432	455	0.95
6	12	0.11	3.3	8.8	4.4	1	23	463	485	463	485	0.91
7	12	0.012	0.37	11.9	1.7	2	23	505	527	505	527	0.92
8	12	0.00029	0.009	16.9	4.0	1	23	534	557	534	557	0.94
9	12	0.0038	0.12	13.4	3.2	1	23	564	586	564	586	0.97
10	12	0.00027	0.0082	17.1	2.8	1	23	592	614	592	614	0.98
11	12	3e-05	0.00093	20.0	3.5	1	23	620	642	620	642	0.99
12	12	0.0045	0.14	13.2	0.3	6	23	653	671	648	671	0.94

Sequence Information

Coding Sequence: ATGCCGCCCGAGACGACCGCCACCGGCATCGAGCTGACCGATCACACCTGCCGGCTGTGCCTGGCCAACGACCAGGAGATTAGCCCGATGGTGGACGCGCTCAGCCAGGACGAGCTGAAGAATGTCATCGAGGGCTTGCTCAAAATCGAGATGCTCAACAGCGGTCCGTTCCAGAGCGCCTGTTCCAACTGCGTGGTCAAGGTTCGGCTGATCGAGAACATCCGGAACGAGTTCGACAGCAGCAACAAGATATTCGATGTTATGTGGACtcAGTACAAGCGCATTCACTTTCCGGAACCGGTATCGCCTCCGAAGAAGGGACGGCCAAAGGCGGAGAAGTCGAGTCCGAAGGCGCAGAAGATAACGGCGGCGTACATCATCGACGGAATGGTGATTGAGAACACGGAGATTGAGTACGTCCAGGACGAGGCGGCGGAGTTCTTTATCAAGCGCGAAGGTCAGGACAGCATTATTAAGCAGGAGGACGTGGACGATTCGGCTAGCGAGGGCATTCCGGGCGGCGATGATCACGATATGGATGAAACGGTCGAGGAGGAGTACGTGTACGAGGACGTTCCGATGGGCGACGAGGCGAGGATGCAGGTGGAGTATTTGACGGAGGATCCCAAGGAGGGTGGCAAGAAGGACGATGGCGTTGGTGGTGGGGGCGCTGGCGAGCATGAGGAAGAGAAGGATTCCGCTATAAAGGACACGTTCATCGAGGAGGACACCGGCTACTATGACAAGACCATTCCCTGTTGCTACATCTGTCTGGACCGGTTTGACTGCCAGTCTGATGTGGTCACCCACCTGATCGATGTCCACACCGATATGCTGCCTTTCCATTGCGACAAATGTTTGGCTTATTTTGATACGCTGGAGGAAGTCAACAAGCATTACATTTCGCACGTGTACGAGTTCGTTTGCCTTTACTGTCCGCGGAGGTACTGCTCGGAGCAGTACCTGGCCAACCACAACCTGGTCTGCAAGTCGTTCAAGTGCCAGCTGTGCGACGAAACGTTCGAGCTGCAAAGCCACCTAAAGGCGCACCAACGTGCGCTCCACGCGTCCGATGGCCGCACCAACCCGCGCAAACGGAACTCCTGCAACACGTGCGGCAAAGCTTTTGTGCATGCTATCAACTTGATGCGCCATTTGAAGAACAAACGCTGCGTCCGGAACAGCAGCCACGATCTGTTTGACGGCACGGAAATCAAACCCGATCCGGACGCACCGATCGTCGACCTGGAGCTGGACCTGGACGACGACAAGCAGCTCAAAATCCGACCCCCGCTCACCTGCCAAGTTTGCAGCAAGAAACTGGACAGCAACAGCAGCCTGGCGCGCCACATCGAGAAAGAGCATCAAGATTTCAACATCCCGCTGTTTTCGTGCAACATTTGCCCCAAAAAATTCACCACCTTCGAAAAGTGCATCCGCCACCGAGCCTTCCACAAGAAGTCCAAAAAGCCAATGATCCCCCTCATGAAGAAGGACCCAACCGACGACAACACGTGcaaaatctgcaacaaaaaGTTCCGCCTCGACCACATGCTGCTGAAGCATCTCGCCGAAATCCACCAGCTCACGCTGGAACTGTTCCACTGCGATCAGTGCGGCAAAAAGTTCTCGACCGAGCCGAAGCTGCGCAAGCACCAGTACAACACCCATCGCGAGAACAAGAACCTGTACGTGTGCTCGCACTGCGGCCAAAAGTTCGAGAAGAAGCTCACCCTCAAGGACCACGAGACGAAGCACCTGAACGCGCCCGCCTATCAGTGCGACATCTGCCTCAAAACGTTCATCCACAAGCACAGCCTCGATCGCCACGCGCTCGTGCACTCCGACGAGAAGAACTACGAGTGCGAGTTCTGCCACAAGATGTTCAAGCGGAACACCACGCTGGTCATCCACAGACGAATTCACACCGGCGAGAAGCCGTACGAATGCATTCCGTGCGGCACGCGCTTCATCGACTCGAGCACGCTGATCAAGCACCGGCAGCGGATGCACCCGAAGGCGGATTAA
Protein Sequence: MPPETTATGIELTDHTCRLCLANDQEISPMVDALSQDELKNVIEGLLKIEMLNSGPFQSACSNCVVKVRLIENIRNEFDSSNKIFDVMWTQYKRIHFPEPVSPPKKGRPKAEKSSPKAQKITAAYIIDGMVIENTEIEYVQDEAAEFFIKREGQDSIIKQEDVDDSASEGIPGGDDHDMDETVEEEYVYEDVPMGDEARMQVEYLTEDPKEGGKKDDGVGGGGAGEHEEEKDSAIKDTFIEEDTGYYDKTIPCCYICLDRFDCQSDVVTHLIDVHTDMLPFHCDKCLAYFDTLEEVNKHYISHVYEFVCLYCPRRYCSEQYLANHNLVCKSFKCQLCDETFELQSHLKAHQRALHASDGRTNPRKRNSCNTCGKAFVHAINLMRHLKNKRCVRNSSHDLFDGTEIKPDPDAPIVDLELDLDDDKQLKIRPPLTCQVCSKKLDSNSSLARHIEKEHQDFNIPLFSCNICPKKFTTFEKCIRHRAFHKKSKKPMIPLMKKDPTDDNTCKICNKKFRLDHMLLKHLAEIHQLTLELFHCDQCGKKFSTEPKLRKHQYNTHRENKNLYVCSHCGQKFEKKLTLKDHETKHLNAPAYQCDICLKTFIHKHSLDRHALVHSDEKNYECEFCHKMFKRNTTLVIHRRIHTGEKPYECIPCGTRFIDSSTLIKHRQRMHPKAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01471782;
90% Identity: iTF_00402000;
80% Identity: -