Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:9550961-9558086[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0006 0.018 16.0 3.4 1 23 85 107 85 107 0.98
2 16 0.22 6.7 7.9 0.1 1 23 115 138 115 138 0.93
3 16 0.0016 0.049 14.6 2.0 1 23 157 179 157 179 0.98
4 16 0.0033 0.1 13.6 0.4 1 23 187 210 187 210 0.93
5 16 0.5 15 6.8 2.0 1 23 221 245 221 245 0.95
6 16 0.00057 0.018 16.0 1.5 1 20 256 275 256 277 0.95
7 16 0.00018 0.0056 17.6 4.2 1 23 294 316 294 316 0.99
8 16 0.84 26 6.0 0.0 1 22 382 403 382 405 0.90
9 16 0.00021 0.0065 17.4 4.4 1 23 424 446 424 446 0.98
10 16 0.0021 0.065 14.2 0.3 1 23 454 477 454 477 0.90
11 16 0.3 9.1 7.5 4.3 1 23 497 519 497 519 0.98
12 16 0.00029 0.0088 17.0 2.0 1 21 527 547 527 548 0.96
13 16 2.4 74 4.6 2.2 1 23 588 610 588 610 0.87
14 16 0.0024 0.075 14.0 0.6 1 23 618 641 618 641 0.91
15 16 0.019 0.57 11.3 3.2 1 23 665 687 665 687 0.98
16 16 0.016 0.49 11.5 0.5 1 23 695 719 695 719 0.97

Sequence Information

Coding Sequence
aTGGAAAGTAAAGAAAACcTTCTTGTCAAAATGTCAGCTCAAATCAAACTAGAAGAAGGGGTCGATTGTCCACAATTCCACACTGAAACAATTGTGAAGGAAGAGCTGATCCTGGAGGATGAGCACCCACACCCGGAACCGACATCCCACGAGAACGTAGTCATCTCGGCATACGGTTACGAAATTACCATCAAAAATgaacctctggaggaggaggagccTCTGGATAAGGTCGTCACGGAAGAACCTGCCTTCAGCTGTGACAAATGCAACAAGCAGTTCACCTCGAAGCGCTCGTATAGCGAGCACCTGCTGAAGCACCGGAACTTGGAGAGCAAGCGATTCATGTGCGCGCCATGCCAGAAACCTTTTGGTACGGCAGGCGCGTTGGACACACACGAACGGCGGATGCACGGAGGTGTAAAAAGTGAGCGACCTTCGGAGGAGGCTGAAAGTGCGCCAAAACGGTTCCGCTGTGACAAGTGCGACAAGCAGTTCGACGTGGCGATCTCGTTCAAGATGCACCGCAAGCGGCACCGGGACCTCGACAGCAAGCGCTTCGTGTGCGCACCGTGCCGGAAAATTTTCGCGACGCGGCGCGAGTTGAACCGACACCAGCAGAACGTTCACGGCGGAGGGATTGGCAAGTTGACGTTGCAGTACAAGTGCCGGTACCGGTCGTGCGATACGGTGTGCGATAACAAGGAGAGCTTTGAGGAGCATTTGGAGGAGCACAGGACAGGGCAGACACCGGACGGAAAGCGGCATCGGTGCAAAAAGTGTGACAAGTTCTTTGCCAATGGAACCTCTTTGAAACGACACTTGGAGCTCAATATTTGCGACTATAGGCCGATAGTGCTGGAGGAGGAAGACGGCACCTTTAAATGTTCCACGTGCAGCAAAACGTTTTCCCAGCAGCACCTGATTGACCAACACATCCGAACGCATCTGGGCCGGCCGGAGTTTCGCTTTGCAACGCTGGATTTTACTGAGAAACAGGCGGAGGAGCTGGGCACGGATCCGATCGTTGTGGAGCAGAACGGAGAAGAGTTTTTCAAGTGTCCTATGTGTTTGAAGCTGATTCAACAACACGACACTTGTGTTCGCCACATAGGCGTGCATATCACAAAAGCACGAGCCACGTTCCAGTGTGAAGCGTGTGGATTGTATGTTGCCGACAACAAGGAGCTCGCGCAGCACGCGGCCGCCAAGCACGGCCGGGTCAAATCCGAACCGACCGAGCTCGGTGAATGTGACGAGCAGGGTCTCTTCAGGTGCACCGAGTGCACAAAAACATTCACGCAACGGCGTTTGGTGATGCGCCACTTTCGCAGGCACGAAGCGATGAAGAAGGGCTCGTTCCAGTGTACAATTTGTGAAAAGTATTTTCCGGAAAATGCCGAGTTGATGAAGCACTCGATTGAGAAACACGGTGAGGAGCCAAAAGCGCCGAAGACGACCAAGCTGGAAAAGGACGCCAGTGGGCGGTTCAAATGCACGCAATGTGAGCAAACATTTGAACATCGTCAGCCGTGCGCAGCACACATTCGTAGGCACCAAATCAAGGACAGTGCGCGGTATCAGTGCAAGAAATGTTTGAAGtgCTTCGTCAAACAAGTCGATTTGCAACGTCATGAACGAGCAGCTACCAAGCTGACGGAGAGTTTCTGCAACAAAAATCTAAAGTCGCGCCAACTAAACAAATCGGAGCTCTTAAAGCAAACCGGCAAACCGTATCAGGTCATCGAGGAAAACGACTTATTTATTTGCTCGTCCTGTGGCAAAGTGTTCCTGCAGCGTCCGTTCTGCGTGAGCCACATCCGGAAGCACATCGACCTGGAGCAGGGCAGGTTCCGGTGTGAAACGTGCGAAACGAACTTTGGCACAAACACGGAACTTCGCCGGCATGCGGCCCTGAAGCATGGCACTAGTGCGGGCGTTGAAAGACCACGGCTGGTTCCGATCAAGCTGGAGCAGGACGAGGACGGATGGTTCAAGTGTCCCGAGTGTCCGGAGCGGTTTCAGCAGCGGGTGACGTGCACCAAGCACGTGAAACGACACGAGAATCTTCGCAGTGGAAAGTATCGGTGCGACTTCGAGTCGTGTGAAATGcgtTTCGGATCGAATTTTGAGCTAAAACGGCACGTGTTAGTGCACACAAATGGCCAACCTGCGAATGAAGCTTCTACGTCGAAGGCACCAACTAATATAAAAAAGGAAATTCCAGAGGAAATCGTTTCCGACGCTAACTaa
Protein Sequence
MESKENLLVKMSAQIKLEEGVDCPQFHTETIVKEELILEDEHPHPEPTSHENVVISAYGYEITIKNEPLEEEEPLDKVVTEEPAFSCDKCNKQFTSKRSYSEHLLKHRNLESKRFMCAPCQKPFGTAGALDTHERRMHGGVKSERPSEEAESAPKRFRCDKCDKQFDVAISFKMHRKRHRDLDSKRFVCAPCRKIFATRRELNRHQQNVHGGGIGKLTLQYKCRYRSCDTVCDNKESFEEHLEEHRTGQTPDGKRHRCKKCDKFFANGTSLKRHLELNICDYRPIVLEEEDGTFKCSTCSKTFSQQHLIDQHIRTHLGRPEFRFATLDFTEKQAEELGTDPIVVEQNGEEFFKCPMCLKLIQQHDTCVRHIGVHITKARATFQCEACGLYVADNKELAQHAAAKHGRVKSEPTELGECDEQGLFRCTECTKTFTQRRLVMRHFRRHEAMKKGSFQCTICEKYFPENAELMKHSIEKHGEEPKAPKTTKLEKDASGRFKCTQCEQTFEHRQPCAAHIRRHQIKDSARYQCKKCLKCFVKQVDLQRHERAATKLTESFCNKNLKSRQLNKSELLKQTGKPYQVIEENDLFICSSCGKVFLQRPFCVSHIRKHIDLEQGRFRCETCETNFGTNTELRRHAALKHGTSAGVERPRLVPIKLEQDEDGWFKCPECPERFQQRVTCTKHVKRHENLRSGKYRCDFESCEMRFGSNFELKRHVLVHTNGQPANEASTSKAPTNIKKEIPEEIVSDAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400904;
90% Identity
iTF_00400904;
80% Identity
iTF_00400904;